Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy

We validated an antigen capture enzyme-linked immunosorbent assay (ELISA) in Colombian persons with AIDS and proven histoplasmosis and evaluated the correlation between antigenuria and clinical improvement during follow-up. The sensitivity of the Histoplasma capsulatum ELISA was 86%, and the overall...

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Tipo de recurso:
Fecha de publicación:
2014
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/23675
Acceso en línea:
https://doi.org/10.1128/CVI.00101-14
https://repository.urosario.edu.co/handle/10336/23675
Palabra clave:
Amphotericin B deoxycholate
Fungus antigen
Histoplasma capsulatum antigen
Itraconazole
Unclassified drug
Fungus antigen
Acquired immune deficiency syndrome
Antigen detection
Article
Colombia
Enzyme linked immunosorbent assay
Follow up
Histoplasma capsulatum
Histoplasmosis
Human
Major clinical study
Nonhuman
Priority journal
Sensitivity and specificity
Treatment response
Urinalysis
Validation process
AIDS-Related Opportunistic Infections
Cohort analysis
Diagnostic procedure
Drug monitoring
Enzyme linked immunosorbent assay
Histoplasma
Histoplasmosis
Immunology
Procedures
Prospective study
Urine
Validation study
AIDS-Related Opportunistic Infections
Clinical Laboratory Techniques
Cohort Studies
Colombia
Drug Monitoring
Enzyme-Linked Immunosorbent Assay
Histoplasma
Histoplasmosis
Humans
Prospective Studies
Sensitivity and Specificity
Fungal
Antigens
Rights
License
Abierto (Texto Completo)
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dc.title.spa.fl_str_mv Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy
title Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy
spellingShingle Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy
Amphotericin B deoxycholate
Fungus antigen
Histoplasma capsulatum antigen
Itraconazole
Unclassified drug
Fungus antigen
Acquired immune deficiency syndrome
Antigen detection
Article
Colombia
Enzyme linked immunosorbent assay
Follow up
Histoplasma capsulatum
Histoplasmosis
Human
Major clinical study
Nonhuman
Priority journal
Sensitivity and specificity
Treatment response
Urinalysis
Validation process
AIDS-Related Opportunistic Infections
Cohort analysis
Diagnostic procedure
Drug monitoring
Enzyme linked immunosorbent assay
Histoplasma
Histoplasmosis
Immunology
Procedures
Prospective study
Urine
Validation study
AIDS-Related Opportunistic Infections
Clinical Laboratory Techniques
Cohort Studies
Colombia
Drug Monitoring
Enzyme-Linked Immunosorbent Assay
Histoplasma
Histoplasmosis
Humans
Prospective Studies
Sensitivity and Specificity
Fungal
Antigens
title_short Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy
title_full Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy
title_fullStr Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy
title_full_unstemmed Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy
title_sort Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy
dc.subject.keyword.spa.fl_str_mv Amphotericin B deoxycholate
Fungus antigen
Histoplasma capsulatum antigen
Itraconazole
Unclassified drug
Fungus antigen
Acquired immune deficiency syndrome
Antigen detection
Article
Colombia
Enzyme linked immunosorbent assay
Follow up
Histoplasma capsulatum
Histoplasmosis
Human
Major clinical study
Nonhuman
Priority journal
Sensitivity and specificity
Treatment response
Urinalysis
Validation process
AIDS-Related Opportunistic Infections
Cohort analysis
Diagnostic procedure
Drug monitoring
Enzyme linked immunosorbent assay
Histoplasma
Histoplasmosis
Immunology
Procedures
Prospective study
Urine
Validation study
AIDS-Related Opportunistic Infections
Clinical Laboratory Techniques
Cohort Studies
Colombia
Drug Monitoring
Enzyme-Linked Immunosorbent Assay
Histoplasma
Histoplasmosis
Humans
Prospective Studies
Sensitivity and Specificity
topic Amphotericin B deoxycholate
Fungus antigen
Histoplasma capsulatum antigen
Itraconazole
Unclassified drug
Fungus antigen
Acquired immune deficiency syndrome
Antigen detection
Article
Colombia
Enzyme linked immunosorbent assay
Follow up
Histoplasma capsulatum
Histoplasmosis
Human
Major clinical study
Nonhuman
Priority journal
Sensitivity and specificity
Treatment response
Urinalysis
Validation process
AIDS-Related Opportunistic Infections
Cohort analysis
Diagnostic procedure
Drug monitoring
Enzyme linked immunosorbent assay
Histoplasma
Histoplasmosis
Immunology
Procedures
Prospective study
Urine
Validation study
AIDS-Related Opportunistic Infections
Clinical Laboratory Techniques
Cohort Studies
Colombia
Drug Monitoring
Enzyme-Linked Immunosorbent Assay
Histoplasma
Histoplasmosis
Humans
Prospective Studies
Sensitivity and Specificity
Fungal
Antigens
dc.subject.keyword.eng.fl_str_mv Fungal
Antigens
description We validated an antigen capture enzyme-linked immunosorbent assay (ELISA) in Colombian persons with AIDS and proven histoplasmosis and evaluated the correlation between antigenuria and clinical improvement during follow-up. The sensitivity of the Histoplasma capsulatum ELISA was 86%, and the overall specificity was 94%. The antigen test successfully monitored the response to therapy. Copyright © 2014, American Society for Microbiology. All Rights Reserved.
publishDate 2014
dc.date.created.spa.fl_str_mv 2014
dc.date.accessioned.none.fl_str_mv 2020-05-26T00:04:19Z
dc.date.available.none.fl_str_mv 2020-05-26T00:04:19Z
dc.type.eng.fl_str_mv article
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.spa.spa.fl_str_mv Artículo
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1128/CVI.00101-14
dc.identifier.issn.none.fl_str_mv 1556679X
15566811
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/23675
url https://doi.org/10.1128/CVI.00101-14
https://repository.urosario.edu.co/handle/10336/23675
identifier_str_mv 1556679X
15566811
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.citationEndPage.none.fl_str_mv 1368
dc.relation.citationIssue.none.fl_str_mv No. 9
dc.relation.citationStartPage.none.fl_str_mv 1364
dc.relation.citationTitle.none.fl_str_mv Clinical and Vaccine Immunology
dc.relation.citationVolume.none.fl_str_mv Vol. 21
dc.relation.ispartof.spa.fl_str_mv Clinical and Vaccine Immunology, ISSN:1556679X, 15566811, Vol.21, No.9 (2014); pp. 1364-1368
dc.relation.uri.spa.fl_str_mv https://www.scopus.com/inward/record.uri?eid=2-s2.0-84940299660&doi=10.1128%2fCVI.00101-14&partnerID=40&md5=4a48ee98c81ae83b719ad81e0609b108
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rights_invalid_str_mv Abierto (Texto Completo)
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