Is primary hyperparathyroidism a pathogenic factor in some conditions mediated by B lymphocytes hyperactivity?
Several clinical cases have shown the association of primary hyperparathyroidism and immune conditions related to B-cell hyperactivity. In some of these cases the treatment of hyperparathyroidism led to the resolution of the autoimmune phenomena. Thus, this paper hypothesizes that high levels of par...
- Autores:
- Tipo de recurso:
- Fecha de publicación:
- 2013
- Institución:
- Universidad del Rosario
- Repositorio:
- Repositorio EdocUR - U. Rosario
- Idioma:
- eng
- OAI Identifier:
- oai:repository.urosario.edu.co:10336/22570
- Acceso en línea:
- https://doi.org/10.1016/j.mehy.2013.03.044
https://repository.urosario.edu.co/handle/10336/22570
- Palabra clave:
- Interleukin 6
Parathyroid hormone
Article
Autoimmunity
B lymphocyte
Disease association
Hematopoietic system
Hormone action
Human
Hypothesis
Interferon production
Kidney failure
Leukocyte disorder
Lymphocyte function
Parathyroidectomy
Primary hyperparathyroidism
B-lymphocytes
Humans
Parathyroid hormone
primary
theoretical
Hyperparathyroidism
Models
- Rights
- License
- Abierto (Texto Completo)
| Summary: | Several clinical cases have shown the association of primary hyperparathyroidism and immune conditions related to B-cell hyperactivity. In some of these cases the treatment of hyperparathyroidism led to the resolution of the autoimmune phenomena. Thus, this paper hypothesizes that high levels of parathyroid hormone (PTH) may modify B lymphocytes function and induce the development of autoimmunity mediated by B-cell hyperactivity. © 2013 Elsevier Ltd. |
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