Uso de Amigdalina en pacientes con cáncer: revisión sistemática de alcance

Antecedentes: El cáncer es una de las enfermedades crónicas con mayor morbimortalidad a nivel mundial. Se ha incrementado la preferencia de terapias alternativas en pacientes con cáncer como es la Amigdalina, pero se desconoce la extensión y naturaleza de la literatura respecto de ésta. Objetivo: De...

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Autores:
Tipo de recurso:
Fecha de publicación:
2019
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
spa
OAI Identifier:
oai:repository.urosario.edu.co:10336/20396
Acceso en línea:
https://doi.org/10.48713/10336_20396
https://repository.urosario.edu.co/handle/10336/20396
Palabra clave:
Laetrile
Amigdalina
Amigdalosida
Neoplasia
Efectividad
Ciencias médicas, Medicina
Laetrile
Amygdalin
Amygdaloside
Neoplasm
Effectiveness
Medicina
Epidemiología
Rights
License
Atribución-SinDerivadas 2.5 Colombia
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oai_identifier_str oai:repository.urosario.edu.co:10336/20396
network_acronym_str EDOCUR2
network_name_str Repositorio EdocUR - U. Rosario
repository_id_str
dc.title.spa.fl_str_mv Uso de Amigdalina en pacientes con cáncer: revisión sistemática de alcance
title Uso de Amigdalina en pacientes con cáncer: revisión sistemática de alcance
spellingShingle Uso de Amigdalina en pacientes con cáncer: revisión sistemática de alcance
Laetrile
Amigdalina
Amigdalosida
Neoplasia
Efectividad
Ciencias médicas, Medicina
Laetrile
Amygdalin
Amygdaloside
Neoplasm
Effectiveness
Medicina
Epidemiología
title_short Uso de Amigdalina en pacientes con cáncer: revisión sistemática de alcance
title_full Uso de Amigdalina en pacientes con cáncer: revisión sistemática de alcance
title_fullStr Uso de Amigdalina en pacientes con cáncer: revisión sistemática de alcance
title_full_unstemmed Uso de Amigdalina en pacientes con cáncer: revisión sistemática de alcance
title_sort Uso de Amigdalina en pacientes con cáncer: revisión sistemática de alcance
dc.contributor.advisor.none.fl_str_mv Ondo Méndez, Alejandro Oyono
Barragán González, Ana María
dc.subject.spa.fl_str_mv Laetrile
Amigdalina
Amigdalosida
Neoplasia
Efectividad
topic Laetrile
Amigdalina
Amigdalosida
Neoplasia
Efectividad
Ciencias médicas, Medicina
Laetrile
Amygdalin
Amygdaloside
Neoplasm
Effectiveness
Medicina
Epidemiología
dc.subject.ddc.spa.fl_str_mv Ciencias médicas, Medicina
dc.subject.keyword.spa.fl_str_mv Laetrile
Amygdalin
Amygdaloside
Neoplasm
Effectiveness
dc.subject.lemb.spa.fl_str_mv Medicina
Epidemiología
description Antecedentes: El cáncer es una de las enfermedades crónicas con mayor morbimortalidad a nivel mundial. Se ha incrementado la preferencia de terapias alternativas en pacientes con cáncer como es la Amigdalina, pero se desconoce la extensión y naturaleza de la literatura respecto de ésta. Objetivo: Describir la naturaleza, variedad y extensión de la literatura alrededor del uso de Amigdalina en pacientes con cáncer. Metodología: Revisión sistemática de literatura de alcance. Se consultaron las bases MEDLINE a través de PUBMED, EMBASE, LILACS y literatura gris en google scholar. Se incluyeron estudios en humanos o tejido humano (in vitro) con cualquier tipo de cáncer, toda presentación y vías de administración de la Amigdalina. Tres revisores (SM, NC y BV) independientemente, tamizaron y extrajeron datos. Se sintetizó en: autores, año de publicación, país, tipo de estudio, tamaño de muestra, población y tipo de intervención. Resultados: De 2.402 referencias se removieron duplicados. En el tamizaje de título y resumen se excluyen 399 artículos. De 216 artículos completos se incluyeron 35 en la síntesis. Se reportaron revisiones narrativas (n = 15), estudios experimentales in vitro (n=12), reportes de casos (n=4), revisiones sistemáticas (n=2) y observacionales (n=2). El principal país en publicar fue Estados Unidos, seguido por Alemania. Discusión: No se recuperó toda la evidencia alrededor del uso de Amigdalina. Esto hace mas compleja la interpretación y el análisis de los datos recolectados. Conclusión: No hubo discrepancia entre los autores para no recomendar el uso de Amigdalina como tratamiento para pacientes con cáncer.
publishDate 2019
dc.date.accessioned.none.fl_str_mv 2019-10-07T12:07:32Z
dc.date.available.none.fl_str_mv 2019-10-07T12:07:32Z
dc.date.created.none.fl_str_mv 2019-09-06
dc.type.eng.fl_str_mv bachelorThesis
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_7a1f
dc.type.document.spa.fl_str_mv Revisión sistemática
dc.type.spa.spa.fl_str_mv Trabajo de grado
dc.identifier.doi.none.fl_str_mv https://doi.org/10.48713/10336_20396
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/20396
url https://doi.org/10.48713/10336_20396
https://repository.urosario.edu.co/handle/10336/20396
dc.language.iso.spa.fl_str_mv spa
language spa
dc.rights.spa.fl_str_mv Atribución-SinDerivadas 2.5 Colombia
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.acceso.spa.fl_str_mv Abierto (Texto Completo)
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rights_invalid_str_mv Atribución-SinDerivadas 2.5 Colombia
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dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Universidad del Rosario
dc.publisher.department.spa.fl_str_mv Facultad de medicina
institution Universidad del Rosario
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spelling Ondo Méndez, Alejandro Oyono79831981600Barragán González, Ana María52666902600Milanés Escobar, Sonia AlejandraCuadrado Velásquez, Nelia PatriciaDel Valle Zapata, Brenda MilenaEspecialista en Epidemiología (en Convenio con el CES)Full time5cdb3863-8f47-4828-86c1-4eae972d2b8960001733f36-1a60-49b0-9c1b-2ecd51d554a2600e3db1791-d2ee-4880-9b72-96e8951255256002019-10-07T12:07:32Z2019-10-07T12:07:32Z2019-09-06Antecedentes: El cáncer es una de las enfermedades crónicas con mayor morbimortalidad a nivel mundial. Se ha incrementado la preferencia de terapias alternativas en pacientes con cáncer como es la Amigdalina, pero se desconoce la extensión y naturaleza de la literatura respecto de ésta. Objetivo: Describir la naturaleza, variedad y extensión de la literatura alrededor del uso de Amigdalina en pacientes con cáncer. Metodología: Revisión sistemática de literatura de alcance. Se consultaron las bases MEDLINE a través de PUBMED, EMBASE, LILACS y literatura gris en google scholar. Se incluyeron estudios en humanos o tejido humano (in vitro) con cualquier tipo de cáncer, toda presentación y vías de administración de la Amigdalina. Tres revisores (SM, NC y BV) independientemente, tamizaron y extrajeron datos. Se sintetizó en: autores, año de publicación, país, tipo de estudio, tamaño de muestra, población y tipo de intervención. Resultados: De 2.402 referencias se removieron duplicados. En el tamizaje de título y resumen se excluyen 399 artículos. De 216 artículos completos se incluyeron 35 en la síntesis. Se reportaron revisiones narrativas (n = 15), estudios experimentales in vitro (n=12), reportes de casos (n=4), revisiones sistemáticas (n=2) y observacionales (n=2). El principal país en publicar fue Estados Unidos, seguido por Alemania. Discusión: No se recuperó toda la evidencia alrededor del uso de Amigdalina. Esto hace mas compleja la interpretación y el análisis de los datos recolectados. Conclusión: No hubo discrepancia entre los autores para no recomendar el uso de Amigdalina como tratamiento para pacientes con cáncer.Background: Cancer is one of the chronic diseases with the highest morbidity and mortality worldwide. The preference of alternative therapies in patients with cancer such as Amygdalin has increased, but the extent and nature of the literature regarding this is unknown. Objective: Describe the nature, variety and extent of the literature surrounding the use of Amygdalin in cancer patients. Methodology: Systematic review of scope literature. The MEDLINE bases were consulted through PUBMED, EMBASE, LILACS and gray literature in google scholar. Studies in human or human tissue (in vitro) with any type of cancer, all presentation and routes of administration of Amygdalin were included. Three reviewers (SM, NC and BV) independently screened and extracted data. It was synthesized in: authors, year of publication, country, type of study, sample size, population and type of intervention. Results: Duplicates were removed from 2,402 references. 399 articles are excluded in title and summary screening. Of 216 full articles, 35 were included in the synthesis. Narrative reviews (n=15), experimental in vitro studies (n=12), case reports (n=4), systematic reviews (n=2) and observational (n=2) were reported. The main country to publish was the United States, followed by Germany. Discussion: All evidence surrounding the use of Amygdalin was not recovered. This makes the interpretation and analysis of the data collected more complex. Conclusion: There was no discrepancy among the authors for not recommending the use of Amygdalin as a treatment for cancer patients.2019-10-07 07:15:01: Script de automatizacion de embargos. 7 de octubre El autor selecciona el tipo de acceso restringido, se asigna embargo por dos años. Se ha realizado la publicación de su documento "Uso de Amigdalina en pacientes con cáncer: revisión sistemática de alcance" en el Repositorio Institucional EdocUR de la Universidad del Rosario. Usted escogió la opción "Restringido (Temporalmente bloqueado)", por lo que el documento ha quedado con embargo hasta el 8 de octubre de 2021, en concordancia con las Políticas de Acceso Abierto de la Universidad. Si usted desea dejarlo con acceso abierto antes de finalizar dicho periodo o si por el contrario desea extender el embargo al finalizar este tiempo, puede enviar un correo a esta misma dirección realizando la solicitud. Tenga en cuenta que los documentos en acceso abierto propician una mayor visibilidad de su producción académica y científica. Se le envía correo 7 de octubre 2019 informando el tiempo de embargo del documento.2021-10-08 01:01:01: Script de automatizacion de embargos. info:eu-repo/date/embargoEnd/2021-10-07application/pdfhttps://doi.org/10.48713/10336_20396 https://repository.urosario.edu.co/handle/10336/20396spaUniversidad del RosarioFacultad de medicinaAtribución-SinDerivadas 2.5 ColombiaAbierto (Texto Completo)EL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma. PARGRAFO: En caso de presentarse cualquier reclamación o acción por parte de un tercero en cuanto a los derechos de autor sobre la obra en cuestión, EL AUTOR, asumirá toda la responsabilidad, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos la universidad actúa como un tercero de buena fe. EL AUTOR, autoriza a LA UNIVERSIDAD DEL ROSARIO, para que en los términos establecidos en la Ley 23 de 1982, Ley 44 de 1993, Decisión andina 351 de 1993, Decreto 460 de 1995 y demás normas generales sobre la materia, utilice y use la obra objeto de la presente autorización. -------------------------------------- POLITICA DE TRATAMIENTO DE DATOS PERSONALES. Declaro que autorizo previa y de forma informada el tratamiento de mis datos personales por parte de LA UNIVERSIDAD DEL ROSARIO para fines académicos y en aplicación de convenios con terceros o servicios conexos con actividades propias de la academia, con estricto cumplimiento de los principios de ley. 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Available from: http://dx.doi.org/10.1007/s00520-006-0168-9instname:Universidad del Rosarioreponame:Repositorio Institucional EdocURLaetrileAmigdalinaAmigdalosidaNeoplasiaEfectividadCiencias médicas, Medicina610600LaetrileAmygdalinAmygdalosideNeoplasmEffectivenessMedicinaEpidemiologíaUso de Amigdalina en pacientes con cáncer: revisión sistemática de alcancebachelorThesisRevisión sistemáticaTrabajo de gradohttp://purl.org/coar/resource_type/c_7a1fORIGINALMilanes Sonia, Cuadrado Nelia, Del Valle Brenda.pdfMilanes Sonia, Cuadrado Nelia, Del Valle Brenda.pdfapplication/pdf603628https://repository.urosario.edu.co/bitstreams/d7bc69c6-74ce-4100-b98e-33e7e6ecd23f/download04d44ff3c29263e32c948a5124eb273aMD51LICENSElicense.txtlicense.txttext/plain1475https://repository.urosario.edu.co/bitstreams/59323b4c-3edb-4d45-af0e-48c15a91d31c/downloadfab9d9ed61d64f6ac005dee3306ae77eMD52CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8805https://repository.urosario.edu.co/bitstreams/78203d2e-053d-4f80-89c4-3931aa097be7/downloaddab767be7a093b539031785b3bf95490MD53TEXTMilanes Sonia, Cuadrado Nelia, Del Valle Brenda.pdf.txtMilanes Sonia, Cuadrado Nelia, Del Valle Brenda.pdf.txtExtracted texttext/plain87458https://repository.urosario.edu.co/bitstreams/4cd6da77-f745-46db-918b-bcf077f19948/downloadef3b134a9412d420c877dfbb7901907aMD54THUMBNAILMilanes Sonia, Cuadrado Nelia, Del Valle Brenda.pdf.jpgMilanes Sonia, Cuadrado Nelia, Del Valle Brenda.pdf.jpgGenerated Thumbnailimage/jpeg2443https://repository.urosario.edu.co/bitstreams/11c6957b-9472-43fc-ac77-38498f5107c2/downloada68a616b1a13baa7daac2c3f0b306963MD5510336/20396oai:repository.urosario.edu.co:10336/203962021-10-08 01:01:02.116614http://creativecommons.org/licenses/by-nd/2.5/co/Atribución-SinDerivadas 2.5 Colombiahttps://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.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