Autoimmune rheumatic diseases in the intensive care unit: experience from a tertiary referral hospital and review of the literature

Autoimmune rheumatic diseases (AIRD) are not uncommon in the general population and up to one third of hospitalized patients with AIRD may need admission to intensive care unit (ICU). This paper describes the causes of admission, the clinical features and outcome of 24 AIRD patients admitted to a me...

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Fecha de publicación:
2005
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/27269
Acceso en línea:
https://doi.org/10.1191/0961203305lu2082oa
https://repository.urosario.edu.co/handle/10336/27269
Palabra clave:
Intensive care units
Mortality
Rheumatic diseases
Rheumatoid arthritis
Systemic lupus erythematosus
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id EDOCUR2_1d9660d331bf66a777c3ffa018ca31a2
oai_identifier_str oai:repository.urosario.edu.co:10336/27269
network_acronym_str EDOCUR2
network_name_str Repositorio EdocUR - U. Rosario
repository_id_str
spelling e038806a-b13c-46c8-a3df-a975e89a1de036ed2b00-d40a-4c0c-a888-f4c645cd52f6e9d219aa-4a06-4f19-88a2-aca830750ccf11904006-ff4b-4811-9d4b-a6dcfaab1da17bbc464a-47d8-4f02-ab5c-e9525c5143e219474778600414186056002020-08-19T14:41:33Z2020-08-19T14:41:33Z2005-04-01Autoimmune rheumatic diseases (AIRD) are not uncommon in the general population and up to one third of hospitalized patients with AIRD may need admission to intensive care unit (ICU). This paper describes the causes of admission, the clinical features and outcome of 24 AIRD patients admitted to a medical ICU from a third level hospital. Thirteen patients had systemic lupus erythematosus (54.2%), three rheumatoid arthritis (12.5%), three pulmonary renal syndrome (12.5%), two dermatopolymyositis (8.3%), two scleroderma (8.3%) and one antiphospholipid syndrome (4.2%). The main causes for ICU admission were rheumatic disease flare-up (37.5%), infection (37.5%) and complications derived from rheumatic disease (29.1%). Mortality during ICU stay was 16.7% (four patients). Excluding shock requiring vasopressor support, no statistical difference was found between survivors and nonsurvivors; although there was a trend to higher test severity scores (APACHE II, ODIN) in nonsurvivors. Our results reveal a lower mortality rate in AIRD patients admitted to the ICU than reported previously. Severity scores such as APACHE II are predictors of mortality in patients with AIRD in the ICU.application/pdfhttps://doi.org/10.1191/0961203305lu2082oaISSN: 0961-2033EISSN: 1477-0962https://repository.urosario.edu.co/handle/10336/27269engSAGE Publications320No. 4315LupusVol. 14Lupus, ISSN: 0961-2033;EISSN: 1477-0962, Vol 14, No.4 (2005); pp. 315-320https://journals.sagepub.com/doi/10.1191/0961203305lu2082oaRestringido (Acceso a grupos específicos)http://purl.org/coar/access_right/c_16ecLupusinstname:Universidad del Rosarioreponame:Repositorio Institucional EdocURIntensive care unitsMortalityRheumatic diseasesRheumatoid arthritisSystemic lupus erythematosusAutoimmune rheumatic diseases in the intensive care unit: experience from a tertiary referral hospital and review of the literatureEnfermedades reumáticas autoinmunes en la unidad de cuidados intensivos: experiencia de un hospital terciario de referencia y revisión de la literaturaarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501Camargo, J FTobón, G JFonseca, NDiaz, J LMolina, FAnaya, Juan-ManuelUribe Alarcon, Maria Victoria10336/27269oai:repository.urosario.edu.co:10336/272692022-05-02 07:37:13.478457https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co
dc.title.spa.fl_str_mv Autoimmune rheumatic diseases in the intensive care unit: experience from a tertiary referral hospital and review of the literature
dc.title.TranslatedTitle.spa.fl_str_mv Enfermedades reumáticas autoinmunes en la unidad de cuidados intensivos: experiencia de un hospital terciario de referencia y revisión de la literatura
title Autoimmune rheumatic diseases in the intensive care unit: experience from a tertiary referral hospital and review of the literature
spellingShingle Autoimmune rheumatic diseases in the intensive care unit: experience from a tertiary referral hospital and review of the literature
Intensive care units
Mortality
Rheumatic diseases
Rheumatoid arthritis
Systemic lupus erythematosus
title_short Autoimmune rheumatic diseases in the intensive care unit: experience from a tertiary referral hospital and review of the literature
title_full Autoimmune rheumatic diseases in the intensive care unit: experience from a tertiary referral hospital and review of the literature
title_fullStr Autoimmune rheumatic diseases in the intensive care unit: experience from a tertiary referral hospital and review of the literature
title_full_unstemmed Autoimmune rheumatic diseases in the intensive care unit: experience from a tertiary referral hospital and review of the literature
title_sort Autoimmune rheumatic diseases in the intensive care unit: experience from a tertiary referral hospital and review of the literature
dc.subject.keyword.spa.fl_str_mv Intensive care units
Mortality
Rheumatic diseases
Rheumatoid arthritis
Systemic lupus erythematosus
topic Intensive care units
Mortality
Rheumatic diseases
Rheumatoid arthritis
Systemic lupus erythematosus
description Autoimmune rheumatic diseases (AIRD) are not uncommon in the general population and up to one third of hospitalized patients with AIRD may need admission to intensive care unit (ICU). This paper describes the causes of admission, the clinical features and outcome of 24 AIRD patients admitted to a medical ICU from a third level hospital. Thirteen patients had systemic lupus erythematosus (54.2%), three rheumatoid arthritis (12.5%), three pulmonary renal syndrome (12.5%), two dermatopolymyositis (8.3%), two scleroderma (8.3%) and one antiphospholipid syndrome (4.2%). The main causes for ICU admission were rheumatic disease flare-up (37.5%), infection (37.5%) and complications derived from rheumatic disease (29.1%). Mortality during ICU stay was 16.7% (four patients). Excluding shock requiring vasopressor support, no statistical difference was found between survivors and nonsurvivors; although there was a trend to higher test severity scores (APACHE II, ODIN) in nonsurvivors. Our results reveal a lower mortality rate in AIRD patients admitted to the ICU than reported previously. Severity scores such as APACHE II are predictors of mortality in patients with AIRD in the ICU.
publishDate 2005
dc.date.created.spa.fl_str_mv 2005-04-01
dc.date.accessioned.none.fl_str_mv 2020-08-19T14:41:33Z
dc.date.available.none.fl_str_mv 2020-08-19T14:41:33Z
dc.type.eng.fl_str_mv article
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.spa.spa.fl_str_mv Artículo
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1191/0961203305lu2082oa
dc.identifier.issn.none.fl_str_mv ISSN: 0961-2033
EISSN: 1477-0962
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/27269
url https://doi.org/10.1191/0961203305lu2082oa
https://repository.urosario.edu.co/handle/10336/27269
identifier_str_mv ISSN: 0961-2033
EISSN: 1477-0962
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.citationEndPage.none.fl_str_mv 320
dc.relation.citationIssue.none.fl_str_mv No. 4
dc.relation.citationStartPage.none.fl_str_mv 315
dc.relation.citationTitle.none.fl_str_mv Lupus
dc.relation.citationVolume.none.fl_str_mv Vol. 14
dc.relation.ispartof.spa.fl_str_mv Lupus, ISSN: 0961-2033;EISSN: 1477-0962, Vol 14, No.4 (2005); pp. 315-320
dc.relation.uri.spa.fl_str_mv https://journals.sagepub.com/doi/10.1191/0961203305lu2082oa
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_16ec
dc.rights.acceso.spa.fl_str_mv Restringido (Acceso a grupos específicos)
rights_invalid_str_mv Restringido (Acceso a grupos específicos)
http://purl.org/coar/access_right/c_16ec
dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv SAGE Publications
dc.source.spa.fl_str_mv Lupus
institution Universidad del Rosario
dc.source.instname.none.fl_str_mv instname:Universidad del Rosario
dc.source.reponame.none.fl_str_mv reponame:Repositorio Institucional EdocUR
repository.name.fl_str_mv Repositorio institucional EdocUR
repository.mail.fl_str_mv edocur@urosario.edu.co
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