Valor pronóstico del índice PvaCO2/CavO2 y el Lactato en paciente con sepsis en las unidades de cuidado intensivo del Hospital MEDERI, septiembre de 2020- septiembre de 2021

Introducción: La sepsis y el shock séptico constituyen un gran problema de salud, la mortalidad es muy alta, y la principal causa de LRA. La identificación temprana de la hipoperfusión tisular es claves en el tratamiento de pacientes con sepsis. Actualmente el lactato se utiliza para evaluar hipoper...

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Fecha de publicación:
2022
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Universidad del Rosario
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Repositorio EdocUR - U. Rosario
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https://doi.org/10.48713/10336_34655
https://repository.urosario.edu.co/handle/10336/34655
Palabra clave:
PavCo2/CavO2
Sepsis
Shock séptico
Lactato
SOFA
Choque
Septico
APACHE
Lesión renal aguda
Mortalidad
UCI
Ciencias médicas, Medicina
PavCo2/CavO2
Sepsis
Septic shock
Shock
Lactate
SOFA
Septic
APACHE
Acute Kidney Injury
Mortality
ICU
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Atribución-NoComercial-CompartirIgual 2.5 Colombia
id EDOCUR2_1d2fdd3850900aa9c5cf8798b3d11cf4
oai_identifier_str oai:repository.urosario.edu.co:10336/34655
network_acronym_str EDOCUR2
network_name_str Repositorio EdocUR - U. Rosario
repository_id_str
dc.title.es.fl_str_mv Valor pronóstico del índice PvaCO2/CavO2 y el Lactato en paciente con sepsis en las unidades de cuidado intensivo del Hospital MEDERI, septiembre de 2020- septiembre de 2021
dc.title.TranslatedTitle.es.fl_str_mv Prognostic value of the PvaCO2/CavO2 index and Lactate in patients with sepsis in the intensive care units of MEDERI Hospital, September 2020-September 2021
title Valor pronóstico del índice PvaCO2/CavO2 y el Lactato en paciente con sepsis en las unidades de cuidado intensivo del Hospital MEDERI, septiembre de 2020- septiembre de 2021
spellingShingle Valor pronóstico del índice PvaCO2/CavO2 y el Lactato en paciente con sepsis en las unidades de cuidado intensivo del Hospital MEDERI, septiembre de 2020- septiembre de 2021
PavCo2/CavO2
Sepsis
Shock séptico
Lactato
SOFA
Choque
Septico
APACHE
Lesión renal aguda
Mortalidad
UCI
Ciencias médicas, Medicina
PavCo2/CavO2
Sepsis
Septic shock
Shock
Lactate
SOFA
Septic
APACHE
Acute Kidney Injury
Mortality
ICU
title_short Valor pronóstico del índice PvaCO2/CavO2 y el Lactato en paciente con sepsis en las unidades de cuidado intensivo del Hospital MEDERI, septiembre de 2020- septiembre de 2021
title_full Valor pronóstico del índice PvaCO2/CavO2 y el Lactato en paciente con sepsis en las unidades de cuidado intensivo del Hospital MEDERI, septiembre de 2020- septiembre de 2021
title_fullStr Valor pronóstico del índice PvaCO2/CavO2 y el Lactato en paciente con sepsis en las unidades de cuidado intensivo del Hospital MEDERI, septiembre de 2020- septiembre de 2021
title_full_unstemmed Valor pronóstico del índice PvaCO2/CavO2 y el Lactato en paciente con sepsis en las unidades de cuidado intensivo del Hospital MEDERI, septiembre de 2020- septiembre de 2021
title_sort Valor pronóstico del índice PvaCO2/CavO2 y el Lactato en paciente con sepsis en las unidades de cuidado intensivo del Hospital MEDERI, septiembre de 2020- septiembre de 2021
dc.contributor.advisor.none.fl_str_mv Cortés, Camilo Andrés
Hernández Somerson, Mario Andrés
Mercado, Mario Andrés
Pinilla, Dario Isaías
Rodriguez Lima, David Rene
dc.subject.es.fl_str_mv PavCo2/CavO2
Sepsis
Shock séptico
Lactato
SOFA
Choque
Septico
APACHE
Lesión renal aguda
Mortalidad
UCI
topic PavCo2/CavO2
Sepsis
Shock séptico
Lactato
SOFA
Choque
Septico
APACHE
Lesión renal aguda
Mortalidad
UCI
Ciencias médicas, Medicina
PavCo2/CavO2
Sepsis
Septic shock
Shock
Lactate
SOFA
Septic
APACHE
Acute Kidney Injury
Mortality
ICU
dc.subject.ddc.es.fl_str_mv Ciencias médicas, Medicina
dc.subject.keyword.es.fl_str_mv PavCo2/CavO2
Sepsis
Septic shock
Shock
Lactate
SOFA
Septic
APACHE
Acute Kidney Injury
Mortality
ICU
description Introducción: La sepsis y el shock séptico constituyen un gran problema de salud, la mortalidad es muy alta, y la principal causa de LRA. La identificación temprana de la hipoperfusión tisular es claves en el tratamiento de pacientes con sepsis. Actualmente el lactato se utiliza para evaluar hipoperfusión tisular con muchos limitantes, se están explorando marcadores adicionales como PvaCO2/CavO2. Materiales y métodos: Estudio observacional de una cohorte retrospectiva, incluyendo pacientes mayores de 18 años con diagnóstico de sepsis y/o choque séptico atendidos en la UCI durante un año, Se describe el valor pronóstico del lactato e índice PvaCO2/CavO2 al momento del diagnóstico de sepsis y 24 horas, asociado con las variables clínicas de ingreso y a las 48 horas, y su relación con la mortalidad a 28 días. Se realizo un análisis bivariado de las variables de importancia. Resultados: Los pacientes del estudio (207) tenían a altos índices de SOFA (10 puntos) y APACHE (26 puntos), choque séptico el 86%, COVID el 82.6%, y lesión renal aguda al ingreso en el 53% y a las 48 horas el 56% de los pacientes. Antes de las 48 horas fallecieron 23.16% de los pacientes, con una mortalidad a los 28 días del 97,1%. El lactato y PvaCO2/CavO2 en promedio estuvo debajo de los valores de hipoperfusión. Conclusión La lesión renal a las 48 horas se asocia a mayor mortalidad a los 28 días. Los pacientes con COVID tenían mayores alteraciones en el intercambio gaseoso. El Lactato y PCO2/CavO2 no se encontró correlación en los pacientes que tenían sepsis.
publishDate 2022
dc.date.accessioned.none.fl_str_mv 2022-08-02T17:09:44Z
dc.date.available.none.fl_str_mv 2022-08-02T17:09:44Z
dc.date.created.none.fl_str_mv 2022-07-18
dc.type.es.fl_str_mv bachelorThesis
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_7a1f
dc.type.document.es.fl_str_mv Trabajo de grado
dc.type.spa.es.fl_str_mv Trabajo de grado
dc.identifier.doi.none.fl_str_mv https://doi.org/10.48713/10336_34655
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/34655
url https://doi.org/10.48713/10336_34655
https://repository.urosario.edu.co/handle/10336/34655
dc.language.iso.es.fl_str_mv spa
language spa
dc.rights.*.fl_str_mv Atribución-NoComercial-CompartirIgual 2.5 Colombia
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.acceso.es.fl_str_mv Abierto (Texto Completo)
dc.rights.uri.*.fl_str_mv http://creativecommons.org/licenses/by-nc-sa/2.5/co/
rights_invalid_str_mv Atribución-NoComercial-CompartirIgual 2.5 Colombia
Abierto (Texto Completo)
http://creativecommons.org/licenses/by-nc-sa/2.5/co/
http://purl.org/coar/access_right/c_abf2
dc.format.extent.es.fl_str_mv 149 pp
dc.format.mimetype.es.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidad del Rosario
dc.publisher.department.none.fl_str_mv Escuela de Medicina y Ciencias de la Salud
dc.publisher.program.none.fl_str_mv Especialización en Medicina Crítica y Cuidado Intensivo
publisher.none.fl_str_mv Universidad del Rosario
institution Universidad del Rosario
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spelling Cortés, Camilo Andrése65e3014-ea97-4617-9cb9-534aa368a880600Hernández Somerson, Mario Andrés9ae442c1-deba-48ae-8aa7-d2eb84d7383e600Mercado, Mario Andrés5a8b411c-4478-489c-ac61-6ec643a3f957600Pinilla, Dario Isaías50d1fd16-36ee-4398-a9dd-2283d2a6c7fc600Rodriguez Lima, David Reneddeda4bc-05f4-4383-a85b-6615d86b1790600Corrales Cruz, Isis JohannaEspecialista en Medicina Crítica y Cuidado IntensivoMaestríaFull timed806db1d-924c-4785-8181-2c2d6979d4c86002022-08-02T17:09:44Z2022-08-02T17:09:44Z2022-07-18Introducción: La sepsis y el shock séptico constituyen un gran problema de salud, la mortalidad es muy alta, y la principal causa de LRA. La identificación temprana de la hipoperfusión tisular es claves en el tratamiento de pacientes con sepsis. Actualmente el lactato se utiliza para evaluar hipoperfusión tisular con muchos limitantes, se están explorando marcadores adicionales como PvaCO2/CavO2. Materiales y métodos: Estudio observacional de una cohorte retrospectiva, incluyendo pacientes mayores de 18 años con diagnóstico de sepsis y/o choque séptico atendidos en la UCI durante un año, Se describe el valor pronóstico del lactato e índice PvaCO2/CavO2 al momento del diagnóstico de sepsis y 24 horas, asociado con las variables clínicas de ingreso y a las 48 horas, y su relación con la mortalidad a 28 días. Se realizo un análisis bivariado de las variables de importancia. Resultados: Los pacientes del estudio (207) tenían a altos índices de SOFA (10 puntos) y APACHE (26 puntos), choque séptico el 86%, COVID el 82.6%, y lesión renal aguda al ingreso en el 53% y a las 48 horas el 56% de los pacientes. Antes de las 48 horas fallecieron 23.16% de los pacientes, con una mortalidad a los 28 días del 97,1%. El lactato y PvaCO2/CavO2 en promedio estuvo debajo de los valores de hipoperfusión. Conclusión La lesión renal a las 48 horas se asocia a mayor mortalidad a los 28 días. Los pacientes con COVID tenían mayores alteraciones en el intercambio gaseoso. El Lactato y PCO2/CavO2 no se encontró correlación en los pacientes que tenían sepsis.Introduction: Sepsis and septic shock are a major health problem, mortality is very high, and the main cause of AKI. Early identification of tissue hypoperfusion is key in the treatment of patients with sepsis. Lactate is currently used to assess tissue hypoperfusion with many limitations, additional markers such as PvaCO2/CavO2 are being explored. Materials and methods: Observational study of a retrospective cohort, including patients older than 18 years with a diagnosis of sepsis and/or septic shock treated in the ICU for one year. The prognostic value of lactate and PavCo2/CavO2 index at the time of diagnosis is described. of sepsis and 24 hours, associated with the clinical variables of admission and at 48 hours, and its relationship with mortality at 28 days. A bivariate analysis of the variables of importance was performed. Results: The study patients (207) had high rates of SOFA (10 points) and APACHE (26 points), septic shock 86%, COVID 82.6%, and acute kidney injury at admission in 53% and at 48 hours 56% of patients. Within 48 hours, 23.16% of the patients died, with a 28-day mortality of 97.1%. Lactate and PavCo2/CavO2 on average were below hypoperfusion values. Conclusion: Kidney injury at 48 hours is associated with higher mortality at 28 days. COVID patients had greater alterations in gas exchange. Lactate and PavCo2/CavO2 were not found to correlate in patients with sepsis.149 ppapplication/pdfhttps://doi.org/10.48713/10336_34655https://repository.urosario.edu.co/handle/10336/34655spaUniversidad del RosarioEscuela de Medicina y Ciencias de la SaludEspecialización en Medicina Crítica y Cuidado IntensivoAtribución-NoComercial-CompartirIgual 2.5 ColombiaAbierto (Texto Completo)EL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma. PARGRAFO: En caso de presentarse cualquier reclamación o acción por parte de un tercero en cuanto a los derechos de autor sobre la obra en cuestión, EL AUTOR, asumirá toda la responsabilidad, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos la universidad actúa como un tercero de buena fe. 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Disponible en: 10.1097/MCC.0000000000000356.instname:Universidad del Rosarioreponame:Repositorio Institucional EdocURPavCo2/CavO2SepsisShock sépticoLactatoSOFAChoqueSepticoAPACHELesión renal agudaMortalidadUCICiencias médicas, Medicina610600PavCo2/CavO2SepsisSeptic shockShockLactateSOFASepticAPACHEAcute Kidney InjuryMortalityICUValor pronóstico del índice PvaCO2/CavO2 y el Lactato en paciente con sepsis en las unidades de cuidado intensivo del Hospital MEDERI, septiembre de 2020- septiembre de 2021Prognostic value of the PvaCO2/CavO2 index and Lactate in patients with sepsis in the intensive care units of MEDERI Hospital, September 2020-September 2021bachelorThesisTrabajo de gradoTrabajo de gradohttp://purl.org/coar/resource_type/c_7a1fORIGINALValor pronóstico del índice Pv-aCo2Ca-vO2 y el Lactato en paciente con diagnóstico de sepsis en la unidad de cuidado intensivo del Hospital Universitario Mayor-MEDERI, en el periodo de Septiembre de 2020 a Septi.pdfValor pronóstico del índice Pv-aCo2Ca-vO2 y el Lactato en paciente con diagnóstico de sepsis en la unidad de cuidado intensivo del Hospital Universitario Mayor-MEDERI, en el periodo de Septiembre de 2020 a Septi.pdfDocumento principalapplication/pdf2753631https://repository.urosario.edu.co/bitstreams/5083eef2-f8b8-4193-8526-edf59aaf1e7e/download06d1053415c8e8942ec252e29ffef175MD51bibliografia.risbibliografia.risBibliografíaapplication/octet-stream122809https://repository.urosario.edu.co/bitstreams/1b365c73-924a-4e00-a33e-965c7dc67f0d/downloadf8ba1e04a3368bbf459b5461542a7cbdMD54CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; 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