Canonical Correlation Analysis in the Study of Cerebral and Peripheral Haemodynamics Interrelations with Systemic Variables in Neonates Supported on ECMO

Neonates supported on extracorporeal membrane oxygenation (ECMO) are at high risk of brain injury due to haemodynamic instability. In order to monitor cerebral and peripheral (muscle) haemodynamic and oxygenation changes in this population we used a dual-channel near-infrared spectroscopy (NIRS) sys...

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Fecha de publicación:
2012
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/28878
Acceso en línea:
https://doi.org/10.1007/978-1-4614-4989-8_4
https://repository.urosario.edu.co/handle/10336/28878
Palabra clave:
ECMO
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id EDOCUR2_16c96c77ad20e7630ea4063104eeaf74
oai_identifier_str oai:repository.urosario.edu.co:10336/28878
network_acronym_str EDOCUR2
network_name_str Repositorio EdocUR - U. Rosario
repository_id_str
spelling 1413951260078cce348-ab39-4c8a-a871-5b29f2dc2126-13234bcff-b74f-4306-9574-2439b6f2c157-1e7b116bc-40a2-478c-91ed-ecf43c6e208b-1f96fd8b0-d3f4-44ec-abe2-9ffa304c31dc-1373c77e3-5093-43fd-831b-0db88cefa50d-12020-08-28T15:49:59Z2020-08-28T15:49:59Z2012-07-21Neonates supported on extracorporeal membrane oxygenation (ECMO) are at high risk of brain injury due to haemodynamic instability. In order to monitor cerebral and peripheral (muscle) haemodynamic and oxygenation changes in this population we used a dual-channel near-infrared spectroscopy (NIRS) system. In addition, to assess interrelations between NIRS and systemic variables, collected simultaneously, canonical correlation analysis (CCA) was employed. CCA can quantify the relationship between a set of variables and assess levels of dependency. In four out of five patients, systemic variables were found to be less inter-related with cerebral rather than peripheral NIRS measurements. Moreover, during ECMO flow manipulations, we found that the interrelation between the systemic and the NIRS cerebral/peripheral variables changed. The CCA method presented here can be used to assess differences between NIRS cerebral and NIRS peripheral responses due to systemic variations which may be indicative of physiological differences in the mechanisms that regulate oxygenation and/or haemodynamics of the brain and the muscle.application/pdfhttps://doi.org/10.1007/978-1-4614-4989-8_4ISBN: 978-1-4614-4771-9https://repository.urosario.edu.co/handle/10336/28878engSpringer Nature2923Advances in Experimental Medicine and BiologyVol. 765Advances in Experimental Medicine and Biology, ISBN: 978-1-4614-4771-9, Vol.765 (2012); pp. 23-29https://link.springer.com/chapter/10.1007/978-1-4614-4989-8_4Restringido (Acceso a grupos específicos)http://purl.org/coar/access_right/c_16ecAdvances in Experimental Medicine and Biologyinstname:Universidad del Rosarioreponame:Repositorio Institucional EdocURECMOCanonical Correlation Analysis in the Study of Cerebral and Peripheral Haemodynamics Interrelations with Systemic Variables in Neonates Supported on ECMOAnálisis de correlación canónica en el estudio de las interrelaciones de la hemodinámica cerebral y periférica con variables sistémicas en recién nacidos admitidos en ECMObookPartParte de librohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_3248Caicedo Dorado, AlexanderElwell, Clare EHoskote, AparnaElliott, Martin JPapademetriou, Maria DVan Huffel, Sabine10336/28878oai:repository.urosario.edu.co:10336/288782021-06-03 00:49:42.567https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co
dc.title.spa.fl_str_mv Canonical Correlation Analysis in the Study of Cerebral and Peripheral Haemodynamics Interrelations with Systemic Variables in Neonates Supported on ECMO
dc.title.TranslatedTitle.spa.fl_str_mv Análisis de correlación canónica en el estudio de las interrelaciones de la hemodinámica cerebral y periférica con variables sistémicas en recién nacidos admitidos en ECMO
title Canonical Correlation Analysis in the Study of Cerebral and Peripheral Haemodynamics Interrelations with Systemic Variables in Neonates Supported on ECMO
spellingShingle Canonical Correlation Analysis in the Study of Cerebral and Peripheral Haemodynamics Interrelations with Systemic Variables in Neonates Supported on ECMO
ECMO
title_short Canonical Correlation Analysis in the Study of Cerebral and Peripheral Haemodynamics Interrelations with Systemic Variables in Neonates Supported on ECMO
title_full Canonical Correlation Analysis in the Study of Cerebral and Peripheral Haemodynamics Interrelations with Systemic Variables in Neonates Supported on ECMO
title_fullStr Canonical Correlation Analysis in the Study of Cerebral and Peripheral Haemodynamics Interrelations with Systemic Variables in Neonates Supported on ECMO
title_full_unstemmed Canonical Correlation Analysis in the Study of Cerebral and Peripheral Haemodynamics Interrelations with Systemic Variables in Neonates Supported on ECMO
title_sort Canonical Correlation Analysis in the Study of Cerebral and Peripheral Haemodynamics Interrelations with Systemic Variables in Neonates Supported on ECMO
dc.subject.keyword.spa.fl_str_mv ECMO
topic ECMO
description Neonates supported on extracorporeal membrane oxygenation (ECMO) are at high risk of brain injury due to haemodynamic instability. In order to monitor cerebral and peripheral (muscle) haemodynamic and oxygenation changes in this population we used a dual-channel near-infrared spectroscopy (NIRS) system. In addition, to assess interrelations between NIRS and systemic variables, collected simultaneously, canonical correlation analysis (CCA) was employed. CCA can quantify the relationship between a set of variables and assess levels of dependency. In four out of five patients, systemic variables were found to be less inter-related with cerebral rather than peripheral NIRS measurements. Moreover, during ECMO flow manipulations, we found that the interrelation between the systemic and the NIRS cerebral/peripheral variables changed. The CCA method presented here can be used to assess differences between NIRS cerebral and NIRS peripheral responses due to systemic variations which may be indicative of physiological differences in the mechanisms that regulate oxygenation and/or haemodynamics of the brain and the muscle.
publishDate 2012
dc.date.created.spa.fl_str_mv 2012-07-21
dc.date.accessioned.none.fl_str_mv 2020-08-28T15:49:59Z
dc.date.available.none.fl_str_mv 2020-08-28T15:49:59Z
dc.type.eng.fl_str_mv bookPart
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_3248
dc.type.spa.spa.fl_str_mv Parte de libro
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1007/978-1-4614-4989-8_4
dc.identifier.issn.none.fl_str_mv ISBN: 978-1-4614-4771-9
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/28878
url https://doi.org/10.1007/978-1-4614-4989-8_4
https://repository.urosario.edu.co/handle/10336/28878
identifier_str_mv ISBN: 978-1-4614-4771-9
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.citationEndPage.none.fl_str_mv 29
dc.relation.citationStartPage.none.fl_str_mv 23
dc.relation.citationTitle.none.fl_str_mv Advances in Experimental Medicine and Biology
dc.relation.citationVolume.none.fl_str_mv Vol. 765
dc.relation.ispartof.spa.fl_str_mv Advances in Experimental Medicine and Biology, ISBN: 978-1-4614-4771-9, Vol.765 (2012); pp. 23-29
dc.relation.uri.spa.fl_str_mv https://link.springer.com/chapter/10.1007/978-1-4614-4989-8_4
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_16ec
dc.rights.acceso.spa.fl_str_mv Restringido (Acceso a grupos específicos)
rights_invalid_str_mv Restringido (Acceso a grupos específicos)
http://purl.org/coar/access_right/c_16ec
dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Springer Nature
dc.source.spa.fl_str_mv Advances in Experimental Medicine and Biology
institution Universidad del Rosario
dc.source.instname.none.fl_str_mv instname:Universidad del Rosario
dc.source.reponame.none.fl_str_mv reponame:Repositorio Institucional EdocUR
repository.name.fl_str_mv Repositorio institucional EdocUR
repository.mail.fl_str_mv edocur@urosario.edu.co
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