Canonical Correlation Analysis in the Study of Cerebral and Peripheral Haemodynamics Interrelations with Systemic Variables in Neonates Supported on ECMO
Neonates supported on extracorporeal membrane oxygenation (ECMO) are at high risk of brain injury due to haemodynamic instability. In order to monitor cerebral and peripheral (muscle) haemodynamic and oxygenation changes in this population we used a dual-channel near-infrared spectroscopy (NIRS) sys...
- Autores:
- Tipo de recurso:
- Fecha de publicación:
- 2012
- Institución:
- Universidad del Rosario
- Repositorio:
- Repositorio EdocUR - U. Rosario
- Idioma:
- eng
- OAI Identifier:
- oai:repository.urosario.edu.co:10336/28878
- Acceso en línea:
- https://doi.org/10.1007/978-1-4614-4989-8_4
https://repository.urosario.edu.co/handle/10336/28878
- Palabra clave:
- ECMO
- Rights
- License
- Restringido (Acceso a grupos específicos)
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1413951260078cce348-ab39-4c8a-a871-5b29f2dc2126-13234bcff-b74f-4306-9574-2439b6f2c157-1e7b116bc-40a2-478c-91ed-ecf43c6e208b-1f96fd8b0-d3f4-44ec-abe2-9ffa304c31dc-1373c77e3-5093-43fd-831b-0db88cefa50d-12020-08-28T15:49:59Z2020-08-28T15:49:59Z2012-07-21Neonates supported on extracorporeal membrane oxygenation (ECMO) are at high risk of brain injury due to haemodynamic instability. In order to monitor cerebral and peripheral (muscle) haemodynamic and oxygenation changes in this population we used a dual-channel near-infrared spectroscopy (NIRS) system. In addition, to assess interrelations between NIRS and systemic variables, collected simultaneously, canonical correlation analysis (CCA) was employed. CCA can quantify the relationship between a set of variables and assess levels of dependency. In four out of five patients, systemic variables were found to be less inter-related with cerebral rather than peripheral NIRS measurements. Moreover, during ECMO flow manipulations, we found that the interrelation between the systemic and the NIRS cerebral/peripheral variables changed. The CCA method presented here can be used to assess differences between NIRS cerebral and NIRS peripheral responses due to systemic variations which may be indicative of physiological differences in the mechanisms that regulate oxygenation and/or haemodynamics of the brain and the muscle.application/pdfhttps://doi.org/10.1007/978-1-4614-4989-8_4ISBN: 978-1-4614-4771-9https://repository.urosario.edu.co/handle/10336/28878engSpringer Nature2923Advances in Experimental Medicine and BiologyVol. 765Advances in Experimental Medicine and Biology, ISBN: 978-1-4614-4771-9, Vol.765 (2012); pp. 23-29https://link.springer.com/chapter/10.1007/978-1-4614-4989-8_4Restringido (Acceso a grupos específicos)http://purl.org/coar/access_right/c_16ecAdvances in Experimental Medicine and Biologyinstname:Universidad del Rosarioreponame:Repositorio Institucional EdocURECMOCanonical Correlation Analysis in the Study of Cerebral and Peripheral Haemodynamics Interrelations with Systemic Variables in Neonates Supported on ECMOAnálisis de correlación canónica en el estudio de las interrelaciones de la hemodinámica cerebral y periférica con variables sistémicas en recién nacidos admitidos en ECMObookPartParte de librohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_3248Caicedo Dorado, AlexanderElwell, Clare EHoskote, AparnaElliott, Martin JPapademetriou, Maria DVan Huffel, Sabine10336/28878oai:repository.urosario.edu.co:10336/288782021-06-03 00:49:42.567https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co |
dc.title.spa.fl_str_mv |
Canonical Correlation Analysis in the Study of Cerebral and Peripheral Haemodynamics Interrelations with Systemic Variables in Neonates Supported on ECMO |
dc.title.TranslatedTitle.spa.fl_str_mv |
Análisis de correlación canónica en el estudio de las interrelaciones de la hemodinámica cerebral y periférica con variables sistémicas en recién nacidos admitidos en ECMO |
title |
Canonical Correlation Analysis in the Study of Cerebral and Peripheral Haemodynamics Interrelations with Systemic Variables in Neonates Supported on ECMO |
spellingShingle |
Canonical Correlation Analysis in the Study of Cerebral and Peripheral Haemodynamics Interrelations with Systemic Variables in Neonates Supported on ECMO ECMO |
title_short |
Canonical Correlation Analysis in the Study of Cerebral and Peripheral Haemodynamics Interrelations with Systemic Variables in Neonates Supported on ECMO |
title_full |
Canonical Correlation Analysis in the Study of Cerebral and Peripheral Haemodynamics Interrelations with Systemic Variables in Neonates Supported on ECMO |
title_fullStr |
Canonical Correlation Analysis in the Study of Cerebral and Peripheral Haemodynamics Interrelations with Systemic Variables in Neonates Supported on ECMO |
title_full_unstemmed |
Canonical Correlation Analysis in the Study of Cerebral and Peripheral Haemodynamics Interrelations with Systemic Variables in Neonates Supported on ECMO |
title_sort |
Canonical Correlation Analysis in the Study of Cerebral and Peripheral Haemodynamics Interrelations with Systemic Variables in Neonates Supported on ECMO |
dc.subject.keyword.spa.fl_str_mv |
ECMO |
topic |
ECMO |
description |
Neonates supported on extracorporeal membrane oxygenation (ECMO) are at high risk of brain injury due to haemodynamic instability. In order to monitor cerebral and peripheral (muscle) haemodynamic and oxygenation changes in this population we used a dual-channel near-infrared spectroscopy (NIRS) system. In addition, to assess interrelations between NIRS and systemic variables, collected simultaneously, canonical correlation analysis (CCA) was employed. CCA can quantify the relationship between a set of variables and assess levels of dependency. In four out of five patients, systemic variables were found to be less inter-related with cerebral rather than peripheral NIRS measurements. Moreover, during ECMO flow manipulations, we found that the interrelation between the systemic and the NIRS cerebral/peripheral variables changed. The CCA method presented here can be used to assess differences between NIRS cerebral and NIRS peripheral responses due to systemic variations which may be indicative of physiological differences in the mechanisms that regulate oxygenation and/or haemodynamics of the brain and the muscle. |
publishDate |
2012 |
dc.date.created.spa.fl_str_mv |
2012-07-21 |
dc.date.accessioned.none.fl_str_mv |
2020-08-28T15:49:59Z |
dc.date.available.none.fl_str_mv |
2020-08-28T15:49:59Z |
dc.type.eng.fl_str_mv |
bookPart |
dc.type.coarversion.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_3248 |
dc.type.spa.spa.fl_str_mv |
Parte de libro |
dc.identifier.doi.none.fl_str_mv |
https://doi.org/10.1007/978-1-4614-4989-8_4 |
dc.identifier.issn.none.fl_str_mv |
ISBN: 978-1-4614-4771-9 |
dc.identifier.uri.none.fl_str_mv |
https://repository.urosario.edu.co/handle/10336/28878 |
url |
https://doi.org/10.1007/978-1-4614-4989-8_4 https://repository.urosario.edu.co/handle/10336/28878 |
identifier_str_mv |
ISBN: 978-1-4614-4771-9 |
dc.language.iso.spa.fl_str_mv |
eng |
language |
eng |
dc.relation.citationEndPage.none.fl_str_mv |
29 |
dc.relation.citationStartPage.none.fl_str_mv |
23 |
dc.relation.citationTitle.none.fl_str_mv |
Advances in Experimental Medicine and Biology |
dc.relation.citationVolume.none.fl_str_mv |
Vol. 765 |
dc.relation.ispartof.spa.fl_str_mv |
Advances in Experimental Medicine and Biology, ISBN: 978-1-4614-4771-9, Vol.765 (2012); pp. 23-29 |
dc.relation.uri.spa.fl_str_mv |
https://link.springer.com/chapter/10.1007/978-1-4614-4989-8_4 |
dc.rights.coar.fl_str_mv |
http://purl.org/coar/access_right/c_16ec |
dc.rights.acceso.spa.fl_str_mv |
Restringido (Acceso a grupos específicos) |
rights_invalid_str_mv |
Restringido (Acceso a grupos específicos) http://purl.org/coar/access_right/c_16ec |
dc.format.mimetype.none.fl_str_mv |
application/pdf |
dc.publisher.spa.fl_str_mv |
Springer Nature |
dc.source.spa.fl_str_mv |
Advances in Experimental Medicine and Biology |
institution |
Universidad del Rosario |
dc.source.instname.none.fl_str_mv |
instname:Universidad del Rosario |
dc.source.reponame.none.fl_str_mv |
reponame:Repositorio Institucional EdocUR |
repository.name.fl_str_mv |
Repositorio institucional EdocUR |
repository.mail.fl_str_mv |
edocur@urosario.edu.co |
_version_ |
1814167629853622272 |