An antibody profile of systemic lupus erythematosus detected by antigen microarray

Patients with systemic lupus erythematosus (SLE) produce antibodies to many different self-antigens. Here, we investigated antibodies in SLE sera using an antigen microarray containing many hundreds of antigens, mostly self-antigens. The aim was to detect sets of antibody reactivities characteristic of SLE patients in each of various clinical states – SLE patients with acute lupus nephritis, SLE patients in renal remission, and SLE patients who had never had renal involvement

• Fecha de publicación: 2010
• Institución: Universidad del Rosario
• Repositorio: Repositorio EdocUR - U. Rosario
• Idioma: eng
• OAI Identifier: oai:repository.urosario.edu.co:10336/26025
• Acceso en línea: https://doi.org/10.1111/j.1365-2567.2010.03245.x; https://repository.urosario.edu.co/handle/10336/26025
• Palabra clave: 12E7 Antigen; Adult; Antibodies; Anticardiolipin; Antibodies; Antinuclear; Antigens; CD; Autoantibodies; Cell Adhesion Molecules; Collagen Type III; Down-Regulation; Female; Herpesvirus 4; Human; Humans; Hyaluronic Acid; Immunoglobulin G; Immunoglobulin M; Insulin-Like Growth Factor Binding Protein 1; Lupus Erythematosus; Systemic; Lupus Nephritis; Male; Middle Aged; Peroxidase; Protein Array Analysis; Sensitivity and Specificity; Up-Regulation
• License: Abierto (Texto Completo)