Virus-Induced Anterior Uveitis (VIAU) in Immunocompromised Patients

Purpose: To describe the clinical characteristics, diagnosis, and treatment of VIAU in immunocompromised patients. Methods: A critical review of literature was performed. Results: Diagnosis and treatment of VIAU in immunocompromised patients may be a challenge due to atypical clinical-courses, sever...

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Autores:
Tipo de recurso:
Fecha de publicación:
2018
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/22716
Acceso en línea:
https://doi.org/10.1080/09273948.2018.1483519
https://repository.urosario.edu.co/handle/10336/22716
Palabra clave:
Aciclovir
Azathioprine
Cd4 antigen
Cyclophosphamide
Cyclosporine
Dexamethasone
Ganciclovir
Infliximab
Methotrexate
Valaciclovir
Valganciclovir
Antiviral therapy
Aqueous humor
Cd4 lymphocyte count
Cochrane library
Cytomegalovirus infection
Cytomegalovirus retinitis
Differential diagnosis
Disease course
Disease severity
Dry eye
Early diagnosis
Embase
Eye examination
Highly active antiretroviral therapy
Human
Immunocompromised patient
Iridocyclitis
Loading drug dose
Medline
Recurrent disease
Review
Systematic review
Virus induced anterior uveitis
Immunology
Innate immunity
Iridocyclitis
Viral eye infection
Virology
Aqueous humor
Humans
Immunocompromised host
Anterior uveitis
Cmv
Differential diagnosis
Ebv
Hiv
Hsv
Immunocompromised
Therapy
Virus
Vzv
innate
viral
anterior
Eye infections
Immunity
Uveitis
Rights
License
Abierto (Texto Completo)
id EDOCUR2_0ed78edcd83573cc66129a99b6dd4943
oai_identifier_str oai:repository.urosario.edu.co:10336/22716
network_acronym_str EDOCUR2
network_name_str Repositorio EdocUR - U. Rosario
repository_id_str
spelling 517013556002020-05-25T23:57:39Z2020-05-25T23:57:39Z2018Purpose: To describe the clinical characteristics, diagnosis, and treatment of VIAU in immunocompromised patients. Methods: A critical review of literature was performed. Results: Diagnosis and treatment of VIAU in immunocompromised patients may be a challenge due to atypical clinical-courses, severe presentations, and more frequent recurrences. A conclusive diagnosis can be made by aqueous-humour PCR-analysis. Visual prognosis depends on early diagnosis and prompt treatment. Frequent ocular examinations are recommended in HIV patients with CD-4-counts below 100 in order to rule out opportunistic ocular coinfections. It is essential to bear in mind the potential side-effects of therapeutic interventions and consider the possibility of Immune Recovery Uveitis (IRU) in eyes with treated viral retinitis after the initiation of HAART. Conclusions: Early diagnosis and treatment of VIAU in immunocompromised patients can be achieved with high suspicion, recognizing clinical features, and obtaining specimens for molecular diagnostic testing in order to avoid usually severe ocular morbidity. ©, © Taylor and Francis Group, LLC.application/pdfhttps://doi.org/10.1080/09273948.2018.14835199273948https://repository.urosario.edu.co/handle/10336/22716engTaylor and Francis Ltd817No. 5807Ocular Immunology and InflammationVol. 26Ocular Immunology and Inflammation, ISSN:9273948, Vol.26, No.5 (2018); pp. 807-817https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049496582&doi=10.1080%2f09273948.2018.1483519&partnerID=40&md5=049054e79dd5ef5e7918dcbe773652ecAbierto (Texto Completo)http://purl.org/coar/access_right/c_abf2instname:Universidad del Rosarioreponame:Repositorio Institucional EdocURAciclovirAzathioprineCd4 antigenCyclophosphamideCyclosporineDexamethasoneGanciclovirInfliximabMethotrexateValaciclovirValganciclovirAntiviral therapyAqueous humorCd4 lymphocyte countCochrane libraryCytomegalovirus infectionCytomegalovirus retinitisDifferential diagnosisDisease courseDisease severityDry eyeEarly diagnosisEmbaseEye examinationHighly active antiretroviral therapyHumanImmunocompromised patientIridocyclitisLoading drug doseMedlineRecurrent diseaseReviewSystematic reviewVirus induced anterior uveitisImmunologyInnate immunityIridocyclitisViral eye infectionVirologyAqueous humorHumansImmunocompromised hostAnterior uveitisCmvDifferential diagnosisEbvHivHsvImmunocompromisedTherapyVirusVzvinnateviralanteriorEye infectionsImmunityUveitisVirus-Induced Anterior Uveitis (VIAU) in Immunocompromised PatientsarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501de-la-Torre, Alejandra10336/22716oai:repository.urosario.edu.co:10336/227162022-05-02 07:37:15.927096https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co
dc.title.spa.fl_str_mv Virus-Induced Anterior Uveitis (VIAU) in Immunocompromised Patients
title Virus-Induced Anterior Uveitis (VIAU) in Immunocompromised Patients
spellingShingle Virus-Induced Anterior Uveitis (VIAU) in Immunocompromised Patients
Aciclovir
Azathioprine
Cd4 antigen
Cyclophosphamide
Cyclosporine
Dexamethasone
Ganciclovir
Infliximab
Methotrexate
Valaciclovir
Valganciclovir
Antiviral therapy
Aqueous humor
Cd4 lymphocyte count
Cochrane library
Cytomegalovirus infection
Cytomegalovirus retinitis
Differential diagnosis
Disease course
Disease severity
Dry eye
Early diagnosis
Embase
Eye examination
Highly active antiretroviral therapy
Human
Immunocompromised patient
Iridocyclitis
Loading drug dose
Medline
Recurrent disease
Review
Systematic review
Virus induced anterior uveitis
Immunology
Innate immunity
Iridocyclitis
Viral eye infection
Virology
Aqueous humor
Humans
Immunocompromised host
Anterior uveitis
Cmv
Differential diagnosis
Ebv
Hiv
Hsv
Immunocompromised
Therapy
Virus
Vzv
innate
viral
anterior
Eye infections
Immunity
Uveitis
title_short Virus-Induced Anterior Uveitis (VIAU) in Immunocompromised Patients
title_full Virus-Induced Anterior Uveitis (VIAU) in Immunocompromised Patients
title_fullStr Virus-Induced Anterior Uveitis (VIAU) in Immunocompromised Patients
title_full_unstemmed Virus-Induced Anterior Uveitis (VIAU) in Immunocompromised Patients
title_sort Virus-Induced Anterior Uveitis (VIAU) in Immunocompromised Patients
dc.subject.keyword.spa.fl_str_mv Aciclovir
Azathioprine
Cd4 antigen
Cyclophosphamide
Cyclosporine
Dexamethasone
Ganciclovir
Infliximab
Methotrexate
Valaciclovir
Valganciclovir
Antiviral therapy
Aqueous humor
Cd4 lymphocyte count
Cochrane library
Cytomegalovirus infection
Cytomegalovirus retinitis
Differential diagnosis
Disease course
Disease severity
Dry eye
Early diagnosis
Embase
Eye examination
Highly active antiretroviral therapy
Human
Immunocompromised patient
Iridocyclitis
Loading drug dose
Medline
Recurrent disease
Review
Systematic review
Virus induced anterior uveitis
Immunology
Innate immunity
Iridocyclitis
Viral eye infection
Virology
Aqueous humor
Humans
Immunocompromised host
Anterior uveitis
Cmv
Differential diagnosis
Ebv
Hiv
Hsv
Immunocompromised
Therapy
Virus
Vzv
topic Aciclovir
Azathioprine
Cd4 antigen
Cyclophosphamide
Cyclosporine
Dexamethasone
Ganciclovir
Infliximab
Methotrexate
Valaciclovir
Valganciclovir
Antiviral therapy
Aqueous humor
Cd4 lymphocyte count
Cochrane library
Cytomegalovirus infection
Cytomegalovirus retinitis
Differential diagnosis
Disease course
Disease severity
Dry eye
Early diagnosis
Embase
Eye examination
Highly active antiretroviral therapy
Human
Immunocompromised patient
Iridocyclitis
Loading drug dose
Medline
Recurrent disease
Review
Systematic review
Virus induced anterior uveitis
Immunology
Innate immunity
Iridocyclitis
Viral eye infection
Virology
Aqueous humor
Humans
Immunocompromised host
Anterior uveitis
Cmv
Differential diagnosis
Ebv
Hiv
Hsv
Immunocompromised
Therapy
Virus
Vzv
innate
viral
anterior
Eye infections
Immunity
Uveitis
dc.subject.keyword.eng.fl_str_mv innate
viral
anterior
Eye infections
Immunity
Uveitis
description Purpose: To describe the clinical characteristics, diagnosis, and treatment of VIAU in immunocompromised patients. Methods: A critical review of literature was performed. Results: Diagnosis and treatment of VIAU in immunocompromised patients may be a challenge due to atypical clinical-courses, severe presentations, and more frequent recurrences. A conclusive diagnosis can be made by aqueous-humour PCR-analysis. Visual prognosis depends on early diagnosis and prompt treatment. Frequent ocular examinations are recommended in HIV patients with CD-4-counts below 100 in order to rule out opportunistic ocular coinfections. It is essential to bear in mind the potential side-effects of therapeutic interventions and consider the possibility of Immune Recovery Uveitis (IRU) in eyes with treated viral retinitis after the initiation of HAART. Conclusions: Early diagnosis and treatment of VIAU in immunocompromised patients can be achieved with high suspicion, recognizing clinical features, and obtaining specimens for molecular diagnostic testing in order to avoid usually severe ocular morbidity. ©, © Taylor and Francis Group, LLC.
publishDate 2018
dc.date.created.spa.fl_str_mv 2018
dc.date.accessioned.none.fl_str_mv 2020-05-25T23:57:39Z
dc.date.available.none.fl_str_mv 2020-05-25T23:57:39Z
dc.type.eng.fl_str_mv article
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.spa.spa.fl_str_mv Artículo
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1080/09273948.2018.1483519
dc.identifier.issn.none.fl_str_mv 9273948
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/22716
url https://doi.org/10.1080/09273948.2018.1483519
https://repository.urosario.edu.co/handle/10336/22716
identifier_str_mv 9273948
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.citationEndPage.none.fl_str_mv 817
dc.relation.citationIssue.none.fl_str_mv No. 5
dc.relation.citationStartPage.none.fl_str_mv 807
dc.relation.citationTitle.none.fl_str_mv Ocular Immunology and Inflammation
dc.relation.citationVolume.none.fl_str_mv Vol. 26
dc.relation.ispartof.spa.fl_str_mv Ocular Immunology and Inflammation, ISSN:9273948, Vol.26, No.5 (2018); pp. 807-817
dc.relation.uri.spa.fl_str_mv https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049496582&doi=10.1080%2f09273948.2018.1483519&partnerID=40&md5=049054e79dd5ef5e7918dcbe773652ec
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.acceso.spa.fl_str_mv Abierto (Texto Completo)
rights_invalid_str_mv Abierto (Texto Completo)
http://purl.org/coar/access_right/c_abf2
dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Taylor and Francis Ltd
institution Universidad del Rosario
dc.source.instname.spa.fl_str_mv instname:Universidad del Rosario
dc.source.reponame.spa.fl_str_mv reponame:Repositorio Institucional EdocUR
repository.name.fl_str_mv Repositorio institucional EdocUR
repository.mail.fl_str_mv edocur@urosario.edu.co
_version_ 1814167550859149312

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