The eukaryotic genome, its reads, and the unfinished assembly

In recent years, readily affordable short read sequences provided by next-generation sequencing (NGS) have become longer and more accurate. This has led to a jump in interest in the utility of NGS-only approaches for exploring eukaryotic genomes. The concept of a static, 'finished' genome...

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Autores:
Tipo de recurso:
Fecha de publicación:
2013
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/24056
Acceso en línea:
https://doi.org/10.1016/j.febslet.2013.05.048
https://repository.urosario.edu.co/handle/10336/24056
Palabra clave:
Accuracy
Algorithm
Article
Bioinformatics
Fungal genome
Fungal strain
Genome analysis
Human
Information processing
Information retrieval
Next generation sequencing
Nonhuman
Priority journal
Reliability
Reproducibility
Sequence analysis
Animals
Base sequence
Chromosome mapping
Eukaryota
Genomics
High-throughput nucleotide sequencing
Humans
Molecular sequence annotation
Eukaryota
Assembly-free genome analysis
Eukaryotic genomics
Microbial strain collection
Next generation sequencing
Object-view separation
dna
human
Genome
Sequence analysis
Rights
License
Abierto (Texto Completo)
id EDOCUR2_0e140ccf5cf93aaa7948649713df3dcc
oai_identifier_str oai:repository.urosario.edu.co:10336/24056
network_acronym_str EDOCUR2
network_name_str Repositorio EdocUR - U. Rosario
repository_id_str
spelling 7dcaba27-e80f-4f46-a0c0-98010bce926a-18d2fbe92-da8c-46a5-ab8d-8b5ea2cd1d5f-1f2a7edfb-a2ef-461e-8062-812cd0c2123b-182ae7fd9-7890-4c2d-8135-9ad6c4018b45-1830c46ff-6a7a-4623-a65e-dc868e2c265b-12020-05-26T00:08:06Z2020-05-26T00:08:06Z2013In recent years, readily affordable short read sequences provided by next-generation sequencing (NGS) have become longer and more accurate. This has led to a jump in interest in the utility of NGS-only approaches for exploring eukaryotic genomes. The concept of a static, 'finished' genome assembly, which still appears to be a faraway goal for many eukaryotes, is yielding to new paradigms. We here motivate an object-view concept where the raw reads are the main, fixed object, and assemblies with their annotations take a role of dynamically changing and modifiable views of that object. © 2013 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.application/pdfhttps://doi.org/10.1016/j.febslet.2013.05.048145793https://repository.urosario.edu.co/handle/10336/24056eng2093No. 142090FEBS LettersVol. 587FEBS Letters, ISSN:145793, Vol.587, No.14 (2013); pp. 2090-2093https://www.scopus.com/inward/record.uri?eid=2-s2.0-84879691390&doi=10.1016%2fj.febslet.2013.05.048&partnerID=40&md5=7ccab6f6de34c006493aef54c8e5936cAbierto (Texto Completo)http://purl.org/coar/access_right/c_abf2instname:Universidad del Rosarioreponame:Repositorio Institucional EdocURAccuracyAlgorithmArticleBioinformaticsFungal genomeFungal strainGenome analysisHumanInformation processingInformation retrievalNext generation sequencingNonhumanPriority journalReliabilityReproducibilitySequence analysisAnimalsBase sequenceChromosome mappingEukaryotaGenomicsHigh-throughput nucleotide sequencingHumansMolecular sequence annotationEukaryotaAssembly-free genome analysisEukaryotic genomicsMicrobial strain collectionNext generation sequencingObject-view separationdnahumanGenomeSequence analysisThe eukaryotic genome, its reads, and the unfinished assemblyarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501Muñoz, José FernandoGallo, Juan EstebanMisas, ElizabethMcEwen, Juan GuillermoClay, Oliver Keatinge10336/24056oai:repository.urosario.edu.co:10336/240562022-05-02 07:37:21.37944https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co
dc.title.spa.fl_str_mv The eukaryotic genome, its reads, and the unfinished assembly
title The eukaryotic genome, its reads, and the unfinished assembly
spellingShingle The eukaryotic genome, its reads, and the unfinished assembly
Accuracy
Algorithm
Article
Bioinformatics
Fungal genome
Fungal strain
Genome analysis
Human
Information processing
Information retrieval
Next generation sequencing
Nonhuman
Priority journal
Reliability
Reproducibility
Sequence analysis
Animals
Base sequence
Chromosome mapping
Eukaryota
Genomics
High-throughput nucleotide sequencing
Humans
Molecular sequence annotation
Eukaryota
Assembly-free genome analysis
Eukaryotic genomics
Microbial strain collection
Next generation sequencing
Object-view separation
dna
human
Genome
Sequence analysis
title_short The eukaryotic genome, its reads, and the unfinished assembly
title_full The eukaryotic genome, its reads, and the unfinished assembly
title_fullStr The eukaryotic genome, its reads, and the unfinished assembly
title_full_unstemmed The eukaryotic genome, its reads, and the unfinished assembly
title_sort The eukaryotic genome, its reads, and the unfinished assembly
dc.subject.keyword.spa.fl_str_mv Accuracy
Algorithm
Article
Bioinformatics
Fungal genome
Fungal strain
Genome analysis
Human
Information processing
Information retrieval
Next generation sequencing
Nonhuman
Priority journal
Reliability
Reproducibility
Sequence analysis
Animals
Base sequence
Chromosome mapping
Eukaryota
Genomics
High-throughput nucleotide sequencing
Humans
Molecular sequence annotation
Eukaryota
Assembly-free genome analysis
Eukaryotic genomics
Microbial strain collection
Next generation sequencing
Object-view separation
topic Accuracy
Algorithm
Article
Bioinformatics
Fungal genome
Fungal strain
Genome analysis
Human
Information processing
Information retrieval
Next generation sequencing
Nonhuman
Priority journal
Reliability
Reproducibility
Sequence analysis
Animals
Base sequence
Chromosome mapping
Eukaryota
Genomics
High-throughput nucleotide sequencing
Humans
Molecular sequence annotation
Eukaryota
Assembly-free genome analysis
Eukaryotic genomics
Microbial strain collection
Next generation sequencing
Object-view separation
dna
human
Genome
Sequence analysis
dc.subject.keyword.eng.fl_str_mv dna
human
Genome
Sequence analysis
description In recent years, readily affordable short read sequences provided by next-generation sequencing (NGS) have become longer and more accurate. This has led to a jump in interest in the utility of NGS-only approaches for exploring eukaryotic genomes. The concept of a static, 'finished' genome assembly, which still appears to be a faraway goal for many eukaryotes, is yielding to new paradigms. We here motivate an object-view concept where the raw reads are the main, fixed object, and assemblies with their annotations take a role of dynamically changing and modifiable views of that object. © 2013 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
publishDate 2013
dc.date.created.spa.fl_str_mv 2013
dc.date.accessioned.none.fl_str_mv 2020-05-26T00:08:06Z
dc.date.available.none.fl_str_mv 2020-05-26T00:08:06Z
dc.type.eng.fl_str_mv article
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.spa.spa.fl_str_mv Artículo
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1016/j.febslet.2013.05.048
dc.identifier.issn.none.fl_str_mv 145793
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/24056
url https://doi.org/10.1016/j.febslet.2013.05.048
https://repository.urosario.edu.co/handle/10336/24056
identifier_str_mv 145793
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.citationEndPage.none.fl_str_mv 2093
dc.relation.citationIssue.none.fl_str_mv No. 14
dc.relation.citationStartPage.none.fl_str_mv 2090
dc.relation.citationTitle.none.fl_str_mv FEBS Letters
dc.relation.citationVolume.none.fl_str_mv Vol. 587
dc.relation.ispartof.spa.fl_str_mv FEBS Letters, ISSN:145793, Vol.587, No.14 (2013); pp. 2090-2093
dc.relation.uri.spa.fl_str_mv https://www.scopus.com/inward/record.uri?eid=2-s2.0-84879691390&doi=10.1016%2fj.febslet.2013.05.048&partnerID=40&md5=7ccab6f6de34c006493aef54c8e5936c
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.acceso.spa.fl_str_mv Abierto (Texto Completo)
rights_invalid_str_mv Abierto (Texto Completo)
http://purl.org/coar/access_right/c_abf2
dc.format.mimetype.none.fl_str_mv application/pdf
institution Universidad del Rosario
dc.source.instname.spa.fl_str_mv instname:Universidad del Rosario
dc.source.reponame.spa.fl_str_mv reponame:Repositorio Institucional EdocUR
repository.name.fl_str_mv Repositorio institucional EdocUR
repository.mail.fl_str_mv edocur@urosario.edu.co
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