The eukaryotic genome, its reads, and the unfinished assembly
In recent years, readily affordable short read sequences provided by next-generation sequencing (NGS) have become longer and more accurate. This has led to a jump in interest in the utility of NGS-only approaches for exploring eukaryotic genomes. The concept of a static, 'finished' genome...
- Autores:
- Tipo de recurso:
- Fecha de publicación:
- 2013
- Institución:
- Universidad del Rosario
- Repositorio:
- Repositorio EdocUR - U. Rosario
- Idioma:
- eng
- OAI Identifier:
- oai:repository.urosario.edu.co:10336/24056
- Acceso en línea:
- https://doi.org/10.1016/j.febslet.2013.05.048
https://repository.urosario.edu.co/handle/10336/24056
- Palabra clave:
- Accuracy
Algorithm
Article
Bioinformatics
Fungal genome
Fungal strain
Genome analysis
Human
Information processing
Information retrieval
Next generation sequencing
Nonhuman
Priority journal
Reliability
Reproducibility
Sequence analysis
Animals
Base sequence
Chromosome mapping
Eukaryota
Genomics
High-throughput nucleotide sequencing
Humans
Molecular sequence annotation
Eukaryota
Assembly-free genome analysis
Eukaryotic genomics
Microbial strain collection
Next generation sequencing
Object-view separation
dna
human
Genome
Sequence analysis
- Rights
- License
- Abierto (Texto Completo)
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oai:repository.urosario.edu.co:10336/24056 |
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Repositorio EdocUR - U. Rosario |
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7dcaba27-e80f-4f46-a0c0-98010bce926a-18d2fbe92-da8c-46a5-ab8d-8b5ea2cd1d5f-1f2a7edfb-a2ef-461e-8062-812cd0c2123b-182ae7fd9-7890-4c2d-8135-9ad6c4018b45-1830c46ff-6a7a-4623-a65e-dc868e2c265b-12020-05-26T00:08:06Z2020-05-26T00:08:06Z2013In recent years, readily affordable short read sequences provided by next-generation sequencing (NGS) have become longer and more accurate. This has led to a jump in interest in the utility of NGS-only approaches for exploring eukaryotic genomes. The concept of a static, 'finished' genome assembly, which still appears to be a faraway goal for many eukaryotes, is yielding to new paradigms. We here motivate an object-view concept where the raw reads are the main, fixed object, and assemblies with their annotations take a role of dynamically changing and modifiable views of that object. © 2013 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.application/pdfhttps://doi.org/10.1016/j.febslet.2013.05.048145793https://repository.urosario.edu.co/handle/10336/24056eng2093No. 142090FEBS LettersVol. 587FEBS Letters, ISSN:145793, Vol.587, No.14 (2013); pp. 2090-2093https://www.scopus.com/inward/record.uri?eid=2-s2.0-84879691390&doi=10.1016%2fj.febslet.2013.05.048&partnerID=40&md5=7ccab6f6de34c006493aef54c8e5936cAbierto (Texto Completo)http://purl.org/coar/access_right/c_abf2instname:Universidad del Rosarioreponame:Repositorio Institucional EdocURAccuracyAlgorithmArticleBioinformaticsFungal genomeFungal strainGenome analysisHumanInformation processingInformation retrievalNext generation sequencingNonhumanPriority journalReliabilityReproducibilitySequence analysisAnimalsBase sequenceChromosome mappingEukaryotaGenomicsHigh-throughput nucleotide sequencingHumansMolecular sequence annotationEukaryotaAssembly-free genome analysisEukaryotic genomicsMicrobial strain collectionNext generation sequencingObject-view separationdnahumanGenomeSequence analysisThe eukaryotic genome, its reads, and the unfinished assemblyarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501Muñoz, José FernandoGallo, Juan EstebanMisas, ElizabethMcEwen, Juan GuillermoClay, Oliver Keatinge10336/24056oai:repository.urosario.edu.co:10336/240562022-05-02 07:37:21.37944https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co |
dc.title.spa.fl_str_mv |
The eukaryotic genome, its reads, and the unfinished assembly |
title |
The eukaryotic genome, its reads, and the unfinished assembly |
spellingShingle |
The eukaryotic genome, its reads, and the unfinished assembly Accuracy Algorithm Article Bioinformatics Fungal genome Fungal strain Genome analysis Human Information processing Information retrieval Next generation sequencing Nonhuman Priority journal Reliability Reproducibility Sequence analysis Animals Base sequence Chromosome mapping Eukaryota Genomics High-throughput nucleotide sequencing Humans Molecular sequence annotation Eukaryota Assembly-free genome analysis Eukaryotic genomics Microbial strain collection Next generation sequencing Object-view separation dna human Genome Sequence analysis |
title_short |
The eukaryotic genome, its reads, and the unfinished assembly |
title_full |
The eukaryotic genome, its reads, and the unfinished assembly |
title_fullStr |
The eukaryotic genome, its reads, and the unfinished assembly |
title_full_unstemmed |
The eukaryotic genome, its reads, and the unfinished assembly |
title_sort |
The eukaryotic genome, its reads, and the unfinished assembly |
dc.subject.keyword.spa.fl_str_mv |
Accuracy Algorithm Article Bioinformatics Fungal genome Fungal strain Genome analysis Human Information processing Information retrieval Next generation sequencing Nonhuman Priority journal Reliability Reproducibility Sequence analysis Animals Base sequence Chromosome mapping Eukaryota Genomics High-throughput nucleotide sequencing Humans Molecular sequence annotation Eukaryota Assembly-free genome analysis Eukaryotic genomics Microbial strain collection Next generation sequencing Object-view separation |
topic |
Accuracy Algorithm Article Bioinformatics Fungal genome Fungal strain Genome analysis Human Information processing Information retrieval Next generation sequencing Nonhuman Priority journal Reliability Reproducibility Sequence analysis Animals Base sequence Chromosome mapping Eukaryota Genomics High-throughput nucleotide sequencing Humans Molecular sequence annotation Eukaryota Assembly-free genome analysis Eukaryotic genomics Microbial strain collection Next generation sequencing Object-view separation dna human Genome Sequence analysis |
dc.subject.keyword.eng.fl_str_mv |
dna human Genome Sequence analysis |
description |
In recent years, readily affordable short read sequences provided by next-generation sequencing (NGS) have become longer and more accurate. This has led to a jump in interest in the utility of NGS-only approaches for exploring eukaryotic genomes. The concept of a static, 'finished' genome assembly, which still appears to be a faraway goal for many eukaryotes, is yielding to new paradigms. We here motivate an object-view concept where the raw reads are the main, fixed object, and assemblies with their annotations take a role of dynamically changing and modifiable views of that object. © 2013 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved. |
publishDate |
2013 |
dc.date.created.spa.fl_str_mv |
2013 |
dc.date.accessioned.none.fl_str_mv |
2020-05-26T00:08:06Z |
dc.date.available.none.fl_str_mv |
2020-05-26T00:08:06Z |
dc.type.eng.fl_str_mv |
article |
dc.type.coarversion.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_6501 |
dc.type.spa.spa.fl_str_mv |
Artículo |
dc.identifier.doi.none.fl_str_mv |
https://doi.org/10.1016/j.febslet.2013.05.048 |
dc.identifier.issn.none.fl_str_mv |
145793 |
dc.identifier.uri.none.fl_str_mv |
https://repository.urosario.edu.co/handle/10336/24056 |
url |
https://doi.org/10.1016/j.febslet.2013.05.048 https://repository.urosario.edu.co/handle/10336/24056 |
identifier_str_mv |
145793 |
dc.language.iso.spa.fl_str_mv |
eng |
language |
eng |
dc.relation.citationEndPage.none.fl_str_mv |
2093 |
dc.relation.citationIssue.none.fl_str_mv |
No. 14 |
dc.relation.citationStartPage.none.fl_str_mv |
2090 |
dc.relation.citationTitle.none.fl_str_mv |
FEBS Letters |
dc.relation.citationVolume.none.fl_str_mv |
Vol. 587 |
dc.relation.ispartof.spa.fl_str_mv |
FEBS Letters, ISSN:145793, Vol.587, No.14 (2013); pp. 2090-2093 |
dc.relation.uri.spa.fl_str_mv |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84879691390&doi=10.1016%2fj.febslet.2013.05.048&partnerID=40&md5=7ccab6f6de34c006493aef54c8e5936c |
dc.rights.coar.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
dc.rights.acceso.spa.fl_str_mv |
Abierto (Texto Completo) |
rights_invalid_str_mv |
Abierto (Texto Completo) http://purl.org/coar/access_right/c_abf2 |
dc.format.mimetype.none.fl_str_mv |
application/pdf |
institution |
Universidad del Rosario |
dc.source.instname.spa.fl_str_mv |
instname:Universidad del Rosario |
dc.source.reponame.spa.fl_str_mv |
reponame:Repositorio Institucional EdocUR |
repository.name.fl_str_mv |
Repositorio institucional EdocUR |
repository.mail.fl_str_mv |
edocur@urosario.edu.co |
_version_ |
1814167706228752384 |