Características clínicas y diferencias de tamaño donante-receptor en trasplante cardíaco de adultos

Introducción: El trasplante de corazón (TC) es una opción bastante sustentada en la evidencia que debe considerarse en los pacientes con falla cardíaca avanzada el adecuado emparejamiento del donante y receptor se ha asociado con menores tasas de mortalidad y disfunción del injerto, en la actualidad...

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Fecha de publicación:
2024
Institución:
Universidad del Rosario
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Repositorio EdocUR - U. Rosario
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spa
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oai:repository.urosario.edu.co:10336/42225
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https://repository.urosario.edu.co/handle/10336/42225
Palabra clave:
Trasplante de corazón
Insuficiencia cardíaca
Mortalidad
Rechazo de injerto
Heart transplantation
Heart failure
Mortality
Graft rejection
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id EDOCUR2_085b58c1032e611f924c4a766a7a7f5f
oai_identifier_str oai:repository.urosario.edu.co:10336/42225
network_acronym_str EDOCUR2
network_name_str Repositorio EdocUR - U. Rosario
repository_id_str
dc.title.none.fl_str_mv Características clínicas y diferencias de tamaño donante-receptor en trasplante cardíaco de adultos
title Características clínicas y diferencias de tamaño donante-receptor en trasplante cardíaco de adultos
spellingShingle Características clínicas y diferencias de tamaño donante-receptor en trasplante cardíaco de adultos
Trasplante de corazón
Insuficiencia cardíaca
Mortalidad
Rechazo de injerto
Heart transplantation
Heart failure
Mortality
Graft rejection
title_short Características clínicas y diferencias de tamaño donante-receptor en trasplante cardíaco de adultos
title_full Características clínicas y diferencias de tamaño donante-receptor en trasplante cardíaco de adultos
title_fullStr Características clínicas y diferencias de tamaño donante-receptor en trasplante cardíaco de adultos
title_full_unstemmed Características clínicas y diferencias de tamaño donante-receptor en trasplante cardíaco de adultos
title_sort Características clínicas y diferencias de tamaño donante-receptor en trasplante cardíaco de adultos
dc.contributor.advisor.none.fl_str_mv Rodríguez González, María Juliana
Cruz Reyes, Danna Lesley
dc.contributor.none.fl_str_mv Tamayo, Maria Fernanda
dc.subject.none.fl_str_mv Trasplante de corazón
Insuficiencia cardíaca
Mortalidad
Rechazo de injerto
topic Trasplante de corazón
Insuficiencia cardíaca
Mortalidad
Rechazo de injerto
Heart transplantation
Heart failure
Mortality
Graft rejection
dc.subject.keyword.none.fl_str_mv Heart transplantation
Heart failure
Mortality
Graft rejection
description Introducción: El trasplante de corazón (TC) es una opción bastante sustentada en la evidencia que debe considerarse en los pacientes con falla cardíaca avanzada el adecuado emparejamiento del donante y receptor se ha asociado con menores tasas de mortalidad y disfunción del injerto, en la actualidad el estándar para definir en emparejamiento es el peso se considera que la valoración por masa cardiaca predicha podría tener un mayor impacto en el emparejamiento para los trasplantes cardiacos. Objetivo: Determinar las características clínicas de la población llevada a primer trasplante cardíaco la Fundación CardioInfantil durante el período de 2005-2022 y evaluar si hay diferencia porcentual en el tamaño predicho de masa ventricular entre donante y receptor de trasplante cardíaco en comparación con la diferencia porcentual de peso corporal entre estos mismos grupos. Métodos: Será un estudio observacional de corte transversal analítico. Resultados esperados: Determinar las características de la población llevada a TC en la Fundación CardioInfantil – Instituto de Cardiología para compartir la experiencia institucional. Conclusión esperada: detectar si existen algunas diferencias entre el emparejamiento del donante receptor por peso corporal frente al emparejamiento por masa cardíaca predicha.
publishDate 2024
dc.date.accessioned.none.fl_str_mv 2024-02-12T13:29:06Z
dc.date.available.none.fl_str_mv 2024-02-12T13:29:06Z
dc.date.created.none.fl_str_mv 2024-02-06
dc.type.none.fl_str_mv bachelorThesis
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_7a1f
dc.type.document.none.fl_str_mv Trabajo de grado
dc.type.spa.none.fl_str_mv Descriptivo observacional retrospectivo
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/42225
url https://repository.urosario.edu.co/handle/10336/42225
dc.language.iso.none.fl_str_mv spa
language spa
dc.rights.*.fl_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.acceso.none.fl_str_mv Abierto (Texto Completo)
dc.rights.uri.*.fl_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
rights_invalid_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
Abierto (Texto Completo)
http://creativecommons.org/licenses/by-nc-nd/4.0/
http://purl.org/coar/access_right/c_abf2
dc.format.extent.none.fl_str_mv 53 pp
dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidad del Rosario
dc.publisher.department.none.fl_str_mv Escuela de Medicina y Ciencias de la Salud
dc.publisher.program.none.fl_str_mv Especialización en Cardiología
publisher.none.fl_str_mv Universidad del Rosario
institution Universidad del Rosario
dc.source.bibliographicCitation.none.fl_str_mv Martinod E, Soubrane O, van Glabeke E, Drouin S, Barrou B, Zarzavadjian Le Bihan A, et al. History of first transplantations: Nothing is ever written. Part II. J Visc Surg. 2021;158(5). 2. Stehlik J, Kobashigawa J, Hunt SA, Reichenspurner H, Kirklin JK. Honoring 50 Years of Clinical Heart Transplantation in Circulation . Circulation. 2018;137(1). 3. McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Böhm M, et al. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Vol. 42, European Heart Journal. 2021. 4. Nino-Murcia A, Pinto Ramirez JL, Nino-Torres L. Organ transplantation in Colombia. Transplantation. 2018;102(11). 5. Velleca A, Shullo MA, Dhital K, Lyster H, Zdenka R. The international Society for Heart and Lung Transplantation (ISHLT) guidelines for the care of heart transplant recipients. J Hear Lung Transplant. 2022;42(5):E1–141. 6. Guglin M, Zucker MJ, Borlaug BA, Breen E, Cleveland J, Johnson MR, et al. Evaluation for Heart Transplantation and LVAD Implantation: JACC Council Perspectives. Vol. 75, Journal of the American College of Cardiology. 2020. 7. Nunoda S. Impact of pretransplant antibodies on outcomes after heart transplantation. Vol. 24, Current Opinion in Organ Transplantation. 2019. 8. Zhu Y, Shudo Y, Lingala B, Joseph Woo Y. The impact of donor sex on heart transplantation outcomes—a study of over 60,000 patients in the United States. J Hear Lung Transplant. 2021;40(8). 9. Jawitz OK, Fudim M, Raman V, Bryner BS, DeVore AD, Mentz RJ, et al. Reassessing Recipient Mortality Under the New Heart Allocation System: An Updated UNOS Registry Analysis. JACC Hear Fail. 2020;8(7). 10. Hsich EM. Matching the market for heart transplantation. Circ Hear Fail. 2016;9(4). 11. Khush KK, Zaroff JG, Nguyen J, Menza R, Goldstein BA. National decline in donor heart utilization with regional variability: 1995-2010. Vol. 15, American Journal of Transplantation. 2015. 12. Wever Pinzon O, Stoddard G, Drakos SG, Gilbert EM, Nativi JN, Budge D, et al. Impact of donor left ventricular hypertrophy on survival after heart transplant. Am J Transplant. 2011;11(12). 13. Wood KJ, Bushell A, Hester J. Regulatory immune cells in transplantation. Vol. 12, Nature Reviews Immunology. 2012. 14. Furiasse N, Kobashigawa JA. Immunosuppression and adult heart transplantation: emerging therapies and opportunities. Vol. 15, Expert Review of Cardiovascular Therapy. 2017. 15. Virani SS, Alonso A, Benjamin EJ, Bittencourt MS, Callaway CW, Carson AP, et al. Heart disease and stroke statistics—2020 update a report from the American Heart Association. Circulation. 2020;141(9). 16. Chambers DC, Perch M, Zuckermann A, Cherikh WS, Harhay MO, HayesJr D, et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-eighth adult lung transplantation report — 2021; Focus on recipient characteristics. J Hear Lung Transplant. 2021;40(10):1060–72. 17. Samman-Tahhan A, Hedley JS, McCue AA, Bjork JB, Georgiopoulou V V., Morris AA, et al. INTERMACS Profiles and Outcomes Among Non–Inotrope-Dependent Outpatients With Heart Failure and Reduced Ejection Fraction. JACC Hear Fail. 2018;6(9). 18. Tackmann E, Dettmer S. Health-related quality of life in adult heart-transplant recipients—a systematic review. Herz. 2020;45(5). 19. Foroutan F, Alba AC, Guyatt G, Duero Posada J, Ng Fat Hing N, Arseneau E, et al. Predictors of 1-year mortality in heart transplant recipients: a systematic review and meta-analysis. Heart. 2018 Jan;104(2):151–60. 20. Alyaydin E, Welp H, Reinecke H, Tuleta I. Predisposing factors for late mortality in heart transplant patients. Cardiol J. 2021 Sep;28(5):746–57. 21. Coniglio AC, Patel CB, Kittleson M, Schlendorf K, Schroder JN, DeVore AD. Innovations in Heart Transplantation: A Review. J Card Fail. 2022 Mar;28(3):467–76. 22. Lo BD, Suarez-Pierre A, Zhou X, Lui C, Hunt MF, Whitman GJ, et al. Matchmaking Just Got Easier: Impact of Phenotypic Donor-Recipient Likeness in Heart Transplantation. Ann Thorac Surg. 2020 Jan;109(1):102–9. 23. Costanzo MR, Costanzo MR, Dipchand A, Starling R, Anderson A, Chan M, et al. The International Society of Heart and Lung Transplantation Guidelines for the care of heart transplant recipients. J Hear Lung Transplant. 2010 Aug;29(8):914–56. 24. Patel ND, Weiss ES, Nwakanma LU, Russell SD, Baumgartner WA, Shah AS, et al. Impact of Donor-to-Recipient Weight Ratio on Survival After Heart Transplantation. Circulation. 2008 Sep;118(14_suppl_1). 25. Bergenfeldt H, Lund LH, Stehlik J, Andersson B, Höglund P, Nilsson J. Time-dependent prognostic effects of recipient and donor age in adult heart transplantation. J Hear Lung Transplant. 2019;38(2):174–83. 26. Lechiancole A, Vendramin I, Sponga S, Guzzi G, Ferrara V, Nalli C, et al. Donor‐recipient age interaction and the impact on clinical results after heart transplantation. Clin Transplant. 2020 Oct;34(10). 27. Ayesta A, Urrútia G, Madrid E, Vernooij RWM, Vicent L, Martínez-Sellés M. Sex-mismatch influence on survival after heart transplantation: A systematic review and meta-analysis of observational studies. Clin Transplant. 2019;33(12). 28. Weiss ES, Allen JG, Patel ND, Russell SD, Baumgartner WA, Shah AS, et al. The Impact of Donor-Recipient Sex Matching on Survival After Orthotopic Heart Transplantation. Circ Hear Fail. 2009 Sep;2(5):401–8. 29. Bergenfeldt H, Stehlik J, Höglund P, Andersson B, Nilsson J. Donor–recipient size matching and mortality in heart transplantation: Influence of body mass index and gender. J Hear Lung Transplant [Internet]. 2017;36(9):940–7. Available from: http://dx.doi.org/10.1016/j.healun.2017.02.002 30. Rudasill SE, Sanaiha Y, Mardock AL, Xing H, Khoury H, Kwon M, et al. Height mismatch: An overlooked component of adult heart transplant outcomes. Clin Transplant. 2020 Jun;34(6). 31. Bluemke DA, Kronmal RA, Lima JAC, Liu K, Olson J, Burke GL, et al. The Relationship of Left Ventricular Mass and Geometry to Incident Cardiovascular Events. J Am Coll Cardiol. 2008 Dec;52(25):2148–55. 32. Kawut SM, Lima JAC, Barr RG, Chahal H, Jain A, Tandri H, et al. Sex and Race Differences in Right Ventricular Structure and Function. Circulation. 2011 Jun;123(22):2542–51. 33. Cheshire C, Quigley R, Claydon S, Von Joel S, Osman M, Kaul P, et al. Validation of predicted heart mass equations by measurement of donor heart mass at time of heart transplantation. Clin Transplant. 2022 Aug;36(8):1–4. 34. Kransdorf EP, Kittleson MM, Benck LR, Patel JK, Chung JS, Esmailian F, et al. Predicted heart mass is the optimal metric for size match in heart transplantation. J Hear Lung Transplant [Internet]. 2019;38(2):156–65. Available from: https://doi.org/10.1016/j.healun.2018.09.017 35. Cheshire C, Kydd A, Nerlekar N, Catarino P, Brown A, Parameshwar J, et al. Size matching in heart transplantation: Is predicted heart mass the optimal method in a United Kingdom cohort? Clin Transplant. 2021;35(3):1–10. 36. Miller RJH, Hedman K, Amsallem M, Tulu Z, Kent W, Fatehi-Hassanabad A, et al. Donor and Recipient Size Matching in Heart Transplantation With Predicted Heart and Lean Body Mass. Semin Thorac Cardiovasc Surg. 2022;34(1):158–67. 37. Santabárbara, J., López, R., Aranda, E. R., Lobo, E., & Aragüés GM. Calculo del tamaño de la muestra e estudios biomédicos. 2015. 38. Colvin M, Smith JM, Ahn Y, Skeans MA, Messick E, Bradbrook K, et al. OPTN/SRTR 2020 Annual Data Report: Heart. Am J Transplant [Internet]. 2022;22(S2):350–437. Available from: https://doi.org/10.1111/ajt.16977 39. Reed RM, Netzer G, Hunsicker L, Mitchell BD, Rajagopal K, Scharf S, et al. Cardiac Size and Sex Matching in Heart Transplantation: Size Matters in Matters of Sex and the Heart. 2014; 40. Khush KK, Cherikh WS, Chambers DC, Harhay MO, Hayes D, Hsich E, et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-sixth adult heart transplantation report — 2019; focus theme: Donor and recipient size match. J Hear Lung Transplant [Internet]. 2019;38(10):1056–66. Available from: https://doi.org/10.1016/j.healun.2019.08.004 41. Ródenas-Alesina E, Foroutan F, Fan CP, Stehlik J, Bartlett I, Tremblay-Gravel M, et al. Predicted Heart Mass: A Tale of 2 Ventricles. Circ Hear Fail. 2023;16(9). 42. Yoon M, Oh J, Lee CJ, Park JJ, Cho HJ, Choi JO, et al. Impact of predicted heart mass-based size matching on survival after heart transplantation in Korea: Analysis of the Korean Organ Transplant Registry. J Hear Lung Transplant. 2022;41(12). 43. Fukushima N, Gundry SR, Razzouk AJ, Bailey LL. Growth of oversized grafts in neonatal heart transplantation. Ann Thorac Surg. 1995;60(6). 44. Kanani M, Hoskote A, Carter C, Burch M, Tsang V, Kostolny M. Increasing donor-recipient weight mismatch in pediatric orthotopic heart transplantation does not adversely affect outcome. Eur J Cardio-thoracic Surg. 2012;41(2). 45. Jayarajan SN, Taghavi S, Komaroff E, Mangi AA. Impact of low donor to recipient weight ratios on cardiac transplantation. J Thorac Cardiovasc Surg. 2013;146(6). 46. Goldstein BA, Thomas L, Zaroff JG, Nguyen J, Menza R, Khush KK. Assessment of heart transplant waitlist time and pre- and post-transplant failure: A mixed methods approach. Epidemiology. 2016;27(4).
Stehlik J, Kobashigawa J, Hunt SA, Reichenspurner H, Kirklin JK. Honoring 50 Years of Clinical Heart Transplantation in Circulation . Circulation. 2018;137(1).
McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Böhm M, et al. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Vol. 42, European Heart Journal. 2021.
McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Böhm M, et al. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Vol. 42, European Heart Journal. 2021.
Velleca A, Shullo MA, Dhital K, Lyster H, Zdenka R. The international Society for Heart and Lung Transplantation (ISHLT) guidelines for the care of heart transplant recipients. J Hear Lung Transplant. 2022;42(5):E1–141.
Guglin M, Zucker MJ, Borlaug BA, Breen E, Cleveland J, Johnson MR, et al. Evaluation for Heart Transplantation and LVAD Implantation: JACC Council Perspectives. Vol. 75, Journal of the American College of Cardiology. 2020.
Nunoda S. Impact of pretransplant antibodies on outcomes after heart transplantation. Vol. 24, Current Opinion in Organ Transplantation. 2019.
Zhu Y, Shudo Y, Lingala B, Joseph Woo Y. The impact of donor sex on heart transplantation outcomes—a study of over 60,000 patients in the United States. J Hear Lung Transplant. 2021;40(8).
Jawitz OK, Fudim M, Raman V, Bryner BS, DeVore AD, Mentz RJ, et al. Reassessing Recipient Mortality Under the New Heart Allocation System: An Updated UNOS Registry Analysis. JACC Hear Fail. 2020;8(7).
Hsich EM. Matching the market for heart transplantation. Circ Hear Fail. 2016;9(4).
Khush KK, Zaroff JG, Nguyen J, Menza R, Goldstein BA. National decline in donor heart utilization with regional variability: 1995-2010. Vol. 15, American Journal of Transplantation. 2015.
Wever Pinzon O, Stoddard G, Drakos SG, Gilbert EM, Nativi JN, Budge D, et al. Impact of donor left ventricular hypertrophy on survival after heart transplant. Am J Transplant. 2011;11(12).
Wood KJ, Bushell A, Hester J. Regulatory immune cells in transplantation. Vol. 12, Nature Reviews Immunology. 2012.
Furiasse N, Kobashigawa JA. Immunosuppression and adult heart transplantation: emerging therapies and opportunities. Vol. 15, Expert Review of Cardiovascular Therapy. 2017.
Virani SS, Alonso A, Benjamin EJ, Bittencourt MS, Callaway CW, Carson AP, et al. Heart disease and stroke statistics—2020 update a report from the American Heart Association. Circulation. 2020;141(9).
Chambers DC, Perch M, Zuckermann A, Cherikh WS, Harhay MO, HayesJr D, et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-eighth adult lung transplantation report — 2021; Focus on recipient characteristics. J Hear Lung Transplant. 2021;40(10):1060–72.
Samman-Tahhan A, Hedley JS, McCue AA, Bjork JB, Georgiopoulou V V., Morris AA, et al. INTERMACS Profiles and Outcomes Among Non–Inotrope-Dependent Outpatients With Heart Failure and Reduced Ejection Fraction. JACC Hear Fail. 2018;6(9).
Tackmann E, Dettmer S. Health-related quality of life in adult heart-transplant recipients—a systematic review. Herz. 2020;45(5).
Foroutan F, Alba AC, Guyatt G, Duero Posada J, Ng Fat Hing N, Arseneau E, et al. Predictors of 1-year mortality in heart transplant recipients: a systematic review and meta-analysis. Heart. 2018 Jan;104(2):151–60.
Alyaydin E, Welp H, Reinecke H, Tuleta I. Predisposing factors for late mortality in heart transplant patients. Cardiol J. 2021 Sep;28(5):746–57.
Coniglio AC, Patel CB, Kittleson M, Schlendorf K, Schroder JN, DeVore AD. Innovations in Heart Transplantation: A Review. J Card Fail. 2022 Mar;28(3):467–76.
Lo BD, Suarez-Pierre A, Zhou X, Lui C, Hunt MF, Whitman GJ, et al. Matchmaking Just Got Easier: Impact of Phenotypic Donor-Recipient Likeness in Heart Transplantation. Ann Thorac Surg. 2020 Jan;109(1):102–9.
Costanzo MR, Costanzo MR, Dipchand A, Starling R, Anderson A, Chan M, et al. The International Society of Heart and Lung Transplantation Guidelines for the care of heart transplant recipients. J Hear Lung Transplant. 2010 Aug;29(8):914–56.
Patel ND, Weiss ES, Nwakanma LU, Russell SD, Baumgartner WA, Shah AS, et al. Impact of Donor-to-Recipient Weight Ratio on Survival After Heart Transplantation. Circulation. 2008 Sep;118(14_suppl_1).
Bergenfeldt H, Lund LH, Stehlik J, Andersson B, Höglund P, Nilsson J. Time-dependent prognostic effects of recipient and donor age in adult heart transplantation. J Hear Lung Transplant. 2019;38(2):174–83.
Lechiancole A, Vendramin I, Sponga S, Guzzi G, Ferrara V, Nalli C, et al. Donor‐recipient age interaction and the impact on clinical results after heart transplantation. Clin Transplant. 2020 Oct;34(10).
Ayesta A, Urrútia G, Madrid E, Vernooij RWM, Vicent L, Martínez-Sellés M. Sex-mismatch influence on survival after heart transplantation: A systematic review and meta-analysis of observational studies. Clin Transplant. 2019;33(12).
Weiss ES, Allen JG, Patel ND, Russell SD, Baumgartner WA, Shah AS, et al. The Impact of Donor-Recipient Sex Matching on Survival After Orthotopic Heart Transplantation. Circ Hear Fail. 2009 Sep;2(5):401–8.
Bergenfeldt H, Stehlik J, Höglund P, Andersson B, Nilsson J. Donor–recipient size matching and mortality in heart transplantation: Influence of body mass index and gender. J Hear Lung Transplant [Internet]. 2017;36(9):940–7. Available from: http://dx.doi.org/10.1016/j.healun.2017.02.002
Rudasill SE, Sanaiha Y, Mardock AL, Xing H, Khoury H, Kwon M, et al. Height mismatch: An overlooked component of adult heart transplant outcomes. Clin Transplant. 2020 Jun;34(6).
Bluemke DA, Kronmal RA, Lima JAC, Liu K, Olson J, Burke GL, et al. The Relationship of Left Ventricular Mass and Geometry to Incident Cardiovascular Events. J Am Coll Cardiol. 2008 Dec;52(25):2148–55.
Kawut SM, Lima JAC, Barr RG, Chahal H, Jain A, Tandri H, et al. Sex and Race Differences in Right Ventricular Structure and Function. Circulation. 2011 Jun;123(22):2542–51.
Cheshire C, Quigley R, Claydon S, Von Joel S, Osman M, Kaul P, et al. Validation of predicted heart mass equations by measurement of donor heart mass at time of heart transplantation. Clin Transplant. 2022 Aug;36(8):1–4.
Kransdorf EP, Kittleson MM, Benck LR, Patel JK, Chung JS, Esmailian F, et al. Predicted heart mass is the optimal metric for size match in heart transplantation. J Hear Lung Transplant [Internet]. 2019;38(2):156–65. Available from: https://doi.org/10.1016/j.healun.2018.09.017
Cheshire C, Kydd A, Nerlekar N, Catarino P, Brown A, Parameshwar J, et al. Size matching in heart transplantation: Is predicted heart mass the optimal method in a United Kingdom cohort? Clin Transplant. 2021;35(3):1–10.
Miller RJH, Hedman K, Amsallem M, Tulu Z, Kent W, Fatehi-Hassanabad A, et al. Donor and Recipient Size Matching in Heart Transplantation With Predicted Heart and Lean Body Mass. Semin Thorac Cardiovasc Surg. 2022;34(1):158–67.
Santabárbara, J., López, R., Aranda, E. R., Lobo, E., & Aragüés GM. Calculo del tamaño de la muestra e estudios biomédicos. 2015.
Colvin M, Smith JM, Ahn Y, Skeans MA, Messick E, Bradbrook K, et al. OPTN/SRTR 2020 Annual Data Report: Heart. Am J Transplant [Internet]. 2022;22(S2):350–437. Available from: https://doi.org/10.1111/ajt.16977
Reed RM, Netzer G, Hunsicker L, Mitchell BD, Rajagopal K, Scharf S, et al. Cardiac Size and Sex Matching in Heart Transplantation: Size Matters in Matters of Sex and the Heart. 2014;
Khush KK, Cherikh WS, Chambers DC, Harhay MO, Hayes D, Hsich E, et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-sixth adult heart transplantation report — 2019; focus theme: Donor and recipient size match. J Hear Lung Transplant [Internet]. 2019;38(10):1056–66. Available from: https://doi.org/10.1016/j.healun.2019.08.004
Ródenas-Alesina E, Foroutan F, Fan CP, Stehlik J, Bartlett I, Tremblay-Gravel M, et al. Predicted Heart Mass: A Tale of 2 Ventricles. Circ Hear Fail. 2023;16(9).
Yoon M, Oh J, Lee CJ, Park JJ, Cho HJ, Choi JO, et al. Impact of predicted heart mass-based size matching on survival after heart transplantation in Korea: Analysis of the Korean Organ Transplant Registry. J Hear Lung Transplant. 2022;41(12).
Fukushima N, Gundry SR, Razzouk AJ, Bailey LL. Growth of oversized grafts in neonatal heart transplantation. Ann Thorac Surg. 1995;60(6).
Kanani M, Hoskote A, Carter C, Burch M, Tsang V, Kostolny M. Increasing donor-recipient weight mismatch in pediatric orthotopic heart transplantation does not adversely affect outcome. Eur J Cardio-thoracic Surg. 2012;41(2).
Jayarajan SN, Taghavi S, Komaroff E, Mangi AA. Impact of low donor to recipient weight ratios on cardiac transplantation. J Thorac Cardiovasc Surg. 2013;146(6).
Martinod E, Soubrane O, van Glabeke E, Drouin S, Barrou B, Zarzavadjian Le Bihan A, et al. History of first transplantations: Nothing is ever written. Part II. J Visc Surg. 2021;158(5). 2. Stehlik J, Kobashigawa J, Hunt SA, Reichenspurner H, Kirklin JK. Honoring 50 Years of Clinical Heart Transplantation in Circulation . Circulation. 2018;137(1). 3. McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Böhm M, et al. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Vol. 42, European Heart Journal. 2021. 4. Nino-Murcia A, Pinto Ramirez JL, Nino-Torres L. Organ transplantation in Colombia. Transplantation. 2018;102(11). 5. Velleca A, Shullo MA, Dhital K, Lyster H, Zdenka R. The international Society for Heart and Lung Transplantation (ISHLT) guidelines for the care of heart transplant recipients. J Hear Lung Transplant. 2022;42(5):E1–141. 6. Guglin M, Zucker MJ, Borlaug BA, Breen E, Cleveland J, Johnson MR, et al. Evaluation for Heart Transplantation and LVAD Implantation: JACC Council Perspectives. Vol. 75, Journal of the American College of Cardiology. 2020. 7. Nunoda S. Impact of pretransplant antibodies on outcomes after heart transplantation. Vol. 24, Current Opinion in Organ Transplantation. 2019. 8. Zhu Y, Shudo Y, Lingala B, Joseph Woo Y. The impact of donor sex on heart transplantation outcomes—a study of over 60,000 patients in the United States. J Hear Lung Transplant. 2021;40(8). 9. Jawitz OK, Fudim M, Raman V, Bryner BS, DeVore AD, Mentz RJ, et al. Reassessing Recipient Mortality Under the New Heart Allocation System: An Updated UNOS Registry Analysis. JACC Hear Fail. 2020;8(7). 10. Hsich EM. Matching the market for heart transplantation. Circ Hear Fail. 2016;9(4). 11. Khush KK, Zaroff JG, Nguyen J, Menza R, Goldstein BA. National decline in donor heart utilization with regional variability: 1995-2010. Vol. 15, American Journal of Transplantation. 2015. 12. Wever Pinzon O, Stoddard G, Drakos SG, Gilbert EM, Nativi JN, Budge D, et al. Impact of donor left ventricular hypertrophy on survival after heart transplant. Am J Transplant. 2011;11(12). 13. Wood KJ, Bushell A, Hester J. Regulatory immune cells in transplantation. Vol. 12, Nature Reviews Immunology. 2012. 14. Furiasse N, Kobashigawa JA. Immunosuppression and adult heart transplantation: emerging therapies and opportunities. Vol. 15, Expert Review of Cardiovascular Therapy. 2017. 15. Virani SS, Alonso A, Benjamin EJ, Bittencourt MS, Callaway CW, Carson AP, et al. Heart disease and stroke statistics—2020 update a report from the American Heart Association. Circulation. 2020;141(9). 16. Chambers DC, Perch M, Zuckermann A, Cherikh WS, Harhay MO, HayesJr D, et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-eighth adult lung transplantation report — 2021; Focus on recipient characteristics. J Hear Lung Transplant. 2021;40(10):1060–72. 17. Samman-Tahhan A, Hedley JS, McCue AA, Bjork JB, Georgiopoulou V V., Morris AA, et al. INTERMACS Profiles and Outcomes Among Non–Inotrope-Dependent Outpatients With Heart Failure and Reduced Ejection Fraction. JACC Hear Fail. 2018;6(9). 18. Tackmann E, Dettmer S. Health-related quality of life in adult heart-transplant recipients—a systematic review. Herz. 2020;45(5). 19. Foroutan F, Alba AC, Guyatt G, Duero Posada J, Ng Fat Hing N, Arseneau E, et al. Predictors of 1-year mortality in heart transplant recipients: a systematic review and meta-analysis. Heart. 2018 Jan;104(2):151–60. 20. Alyaydin E, Welp H, Reinecke H, Tuleta I. Predisposing factors for late mortality in heart transplant patients. Cardiol J. 2021 Sep;28(5):746–57. 21. Coniglio AC, Patel CB, Kittleson M, Schlendorf K, Schroder JN, DeVore AD. Innovations in Heart Transplantation: A Review. J Card Fail. 2022 Mar;28(3):467–76. 22. Lo BD, Suarez-Pierre A, Zhou X, Lui C, Hunt MF, Whitman GJ, et al. Matchmaking Just Got Easier: Impact of Phenotypic Donor-Recipient Likeness in Heart Transplantation. Ann Thorac Surg. 2020 Jan;109(1):102–9. 23. Costanzo MR, Costanzo MR, Dipchand A, Starling R, Anderson A, Chan M, et al. The International Society of Heart and Lung Transplantation Guidelines for the care of heart transplant recipients. J Hear Lung Transplant. 2010 Aug;29(8):914–56. 24. Patel ND, Weiss ES, Nwakanma LU, Russell SD, Baumgartner WA, Shah AS, et al. Impact of Donor-to-Recipient Weight Ratio on Survival After Heart Transplantation. Circulation. 2008 Sep;118(14_suppl_1). 25. Bergenfeldt H, Lund LH, Stehlik J, Andersson B, Höglund P, Nilsson J. Time-dependent prognostic effects of recipient and donor age in adult heart transplantation. J Hear Lung Transplant. 2019;38(2):174–83. 26. Lechiancole A, Vendramin I, Sponga S, Guzzi G, Ferrara V, Nalli C, et al. Donor‐recipient age interaction and the impact on clinical results after heart transplantation. Clin Transplant. 2020 Oct;34(10). 27. Ayesta A, Urrútia G, Madrid E, Vernooij RWM, Vicent L, Martínez-Sellés M. Sex-mismatch influence on survival after heart transplantation: A systematic review and meta-analysis of observational studies. Clin Transplant. 2019;33(12). 28. Weiss ES, Allen JG, Patel ND, Russell SD, Baumgartner WA, Shah AS, et al. The Impact of Donor-Recipient Sex Matching on Survival After Orthotopic Heart Transplantation. Circ Hear Fail. 2009 Sep;2(5):401–8. 29. Bergenfeldt H, Stehlik J, Höglund P, Andersson B, Nilsson J. Donor–recipient size matching and mortality in heart transplantation: Influence of body mass index and gender. J Hear Lung Transplant [Internet]. 2017;36(9):940–7. Available from: http://dx.doi.org/10.1016/j.healun.2017.02.002 30. Rudasill SE, Sanaiha Y, Mardock AL, Xing H, Khoury H, Kwon M, et al. Height mismatch: An overlooked component of adult heart transplant outcomes. Clin Transplant. 2020 Jun;34(6). 31. Bluemke DA, Kronmal RA, Lima JAC, Liu K, Olson J, Burke GL, et al. The Relationship of Left Ventricular Mass and Geometry to Incident Cardiovascular Events. J Am Coll Cardiol. 2008 Dec;52(25):2148–55. 32. Kawut SM, Lima JAC, Barr RG, Chahal H, Jain A, Tandri H, et al. Sex and Race Differences in Right Ventricular Structure and Function. Circulation. 2011 Jun;123(22):2542–51. 33. Cheshire C, Quigley R, Claydon S, Von Joel S, Osman M, Kaul P, et al. Validation of predicted heart mass equations by measurement of donor heart mass at time of heart transplantation. Clin Transplant. 2022 Aug;36(8):1–4. 34. Kransdorf EP, Kittleson MM, Benck LR, Patel JK, Chung JS, Esmailian F, et al. Predicted heart mass is the optimal metric for size match in heart transplantation. J Hear Lung Transplant [Internet]. 2019;38(2):156–65. Available from: https://doi.org/10.1016/j.healun.2018.09.017 35. Cheshire C, Kydd A, Nerlekar N, Catarino P, Brown A, Parameshwar J, et al. Size matching in heart transplantation: Is predicted heart mass the optimal method in a United Kingdom cohort? Clin Transplant. 2021;35(3):1–10. 36. Miller RJH, Hedman K, Amsallem M, Tulu Z, Kent W, Fatehi-Hassanabad A, et al. Donor and Recipient Size Matching in Heart Transplantation With Predicted Heart and Lean Body Mass. Semin Thorac Cardiovasc Surg. 2022;34(1):158–67. 37. Santabárbara, J., López, R., Aranda, E. R., Lobo, E., & Aragüés GM. Calculo del tamaño de la muestra e estudios biomédicos. 2015. 38. Colvin M, Smith JM, Ahn Y, Skeans MA, Messick E, Bradbrook K, et al. OPTN/SRTR 2020 Annual Data Report: Heart. Am J Transplant [Internet]. 2022;22(S2):350–437. Available from: https://doi.org/10.1111/ajt.16977 39. Reed RM, Netzer G, Hunsicker L, Mitchell BD, Rajagopal K, Scharf S, et al. Cardiac Size and Sex Matching in Heart Transplantation: Size Matters in Matters of Sex and the Heart. 2014; 40. Khush KK, Cherikh WS, Chambers DC, Harhay MO, Hayes D, Hsich E, et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-sixth adult heart transplantation report — 2019; focus theme: Donor and recipient size match. J Hear Lung Transplant [Internet]. 2019;38(10):1056–66. Available from: https://doi.org/10.1016/j.healun.2019.08.004 41. Ródenas-Alesina E, Foroutan F, Fan CP, Stehlik J, Bartlett I, Tremblay-Gravel M, et al. Predicted Heart Mass: A Tale of 2 Ventricles. Circ Hear Fail. 2023;16(9). 42. Yoon M, Oh J, Lee CJ, Park JJ, Cho HJ, Choi JO, et al. Impact of predicted heart mass-based size matching on survival after heart transplantation in Korea: Analysis of the Korean Organ Transplant Registry. J Hear Lung Transplant. 2022;41(12). 43. Fukushima N, Gundry SR, Razzouk AJ, Bailey LL. Growth of oversized grafts in neonatal heart transplantation. Ann Thorac Surg. 1995;60(6). 44. Kanani M, Hoskote A, Carter C, Burch M, Tsang V, Kostolny M. Increasing donor-recipient weight mismatch in pediatric orthotopic heart transplantation does not adversely affect outcome. Eur J Cardio-thoracic Surg. 2012;41(2). 45. Jayarajan SN, Taghavi S, Komaroff E, Mangi AA. Impact of low donor to recipient weight ratios on cardiac transplantation. J Thorac Cardiovasc Surg. 2013;146(6). 46. Goldstein BA, Thomas L, Zaroff JG, Nguyen J, Menza R, Khush KK. Assessment of heart transplant waitlist time and pre- and post-transplant failure: A mixed methods approach. Epidemiology. 2016;27(4).
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spelling Tamayo, Maria FernandaRodríguez González, María Julianac8ead788-f83e-44f9-9b23-8e40b9cc1b4d-1Cruz Reyes, Danna Lesley1032415315600Parra Puerto, Jaime AndrésRangel Rivera, Diego AlejandroEspecialista en CardiologíaMaestríaFull time5fe62403-cad9-47fc-8912-40404381cec8-1a34a21fa-6f18-4460-bcd3-0c5e66e92c24-12024-02-12T13:29:06Z2024-02-12T13:29:06Z2024-02-06Introducción: El trasplante de corazón (TC) es una opción bastante sustentada en la evidencia que debe considerarse en los pacientes con falla cardíaca avanzada el adecuado emparejamiento del donante y receptor se ha asociado con menores tasas de mortalidad y disfunción del injerto, en la actualidad el estándar para definir en emparejamiento es el peso se considera que la valoración por masa cardiaca predicha podría tener un mayor impacto en el emparejamiento para los trasplantes cardiacos. Objetivo: Determinar las características clínicas de la población llevada a primer trasplante cardíaco la Fundación CardioInfantil durante el período de 2005-2022 y evaluar si hay diferencia porcentual en el tamaño predicho de masa ventricular entre donante y receptor de trasplante cardíaco en comparación con la diferencia porcentual de peso corporal entre estos mismos grupos. Métodos: Será un estudio observacional de corte transversal analítico. Resultados esperados: Determinar las características de la población llevada a TC en la Fundación CardioInfantil – Instituto de Cardiología para compartir la experiencia institucional. Conclusión esperada: detectar si existen algunas diferencias entre el emparejamiento del donante receptor por peso corporal frente al emparejamiento por masa cardíaca predicha.Introduction: Heart transplantation is an option that is well supported by evidence to consider in patients with advanced heart failure. Objective: To determine the clinical characteristics of the population that underwent the first heart transplant at the Fundación CardioInfantil during the period 2005-2022 and to evaluate whether there is a difference in percentage for the predicted size of ventricular mass between donor and recipient of heart transplant compared to the percentual difference in body weight between these same groups. Methods: This will be an observational, cross-sectional, analytical study. Results: Between 2005-2022, information was collected from 92 patients receiving a CT scan along with the respective donor data, with a median follow-up of 38.8 months, with an all-cause mortality rate of 17.4%. Weight-matching was documented in 20.6% of patients with a median age of 44 years and weight of 64.7 kg. Most of these patients were men and had a mortality at one-year follow-up of 15.8%. According to predicted heart mass matching, the distribution found was paired 13.0% lower than the recipient, 65.2% greater than the recipient, the matched group had an average matching of 17.3% and the one-year mortality rate was much lower than the other two groups, at 1%.53 ppapplication/pdfhttps://repository.urosario.edu.co/handle/10336/42225spaUniversidad del RosarioEscuela de Medicina y Ciencias de la SaludEspecialización en CardiologíaAttribution-NonCommercial-NoDerivatives 4.0 InternationalAbierto (Texto Completo)EL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma. PARGRAFO: En caso de presentarse cualquier reclamación o acción por parte de un tercero en cuanto a los derechos de autor sobre la obra en cuestión, EL AUTOR, asumirá toda la responsabilidad, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos la universidad actúa como un tercero de buena fe. EL AUTOR, autoriza a LA UNIVERSIDAD DEL ROSARIO, para que en los términos establecidos en la Ley 23 de 1982, Ley 44 de 1993, Decisión andina 351 de 1993, Decreto 460 de 1995 y demás normas generales sobre la materia, utilice y use la obra objeto de la presente autorización. -------------------------------------- POLITICA DE TRATAMIENTO DE DATOS PERSONALES. Declaro que autorizo previa y de forma informada el tratamiento de mis datos personales por parte de LA UNIVERSIDAD DEL ROSARIO para fines académicos y en aplicación de convenios con terceros o servicios conexos con actividades propias de la academia, con estricto cumplimiento de los principios de ley. Para el correcto ejercicio de mi derecho de habeas data cuento con la cuenta de correo habeasdata@urosario.edu.co, donde previa identificación podré solicitar la consulta, corrección y supresión de mis datos.http://creativecommons.org/licenses/by-nc-nd/4.0/http://purl.org/coar/access_right/c_abf2Martinod E, Soubrane O, van Glabeke E, Drouin S, Barrou B, Zarzavadjian Le Bihan A, et al. History of first transplantations: Nothing is ever written. Part II. J Visc Surg. 2021;158(5). 2. Stehlik J, Kobashigawa J, Hunt SA, Reichenspurner H, Kirklin JK. Honoring 50 Years of Clinical Heart Transplantation in Circulation . Circulation. 2018;137(1). 3. McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Böhm M, et al. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Vol. 42, European Heart Journal. 2021. 4. Nino-Murcia A, Pinto Ramirez JL, Nino-Torres L. Organ transplantation in Colombia. Transplantation. 2018;102(11). 5. Velleca A, Shullo MA, Dhital K, Lyster H, Zdenka R. The international Society for Heart and Lung Transplantation (ISHLT) guidelines for the care of heart transplant recipients. J Hear Lung Transplant. 2022;42(5):E1–141. 6. Guglin M, Zucker MJ, Borlaug BA, Breen E, Cleveland J, Johnson MR, et al. Evaluation for Heart Transplantation and LVAD Implantation: JACC Council Perspectives. Vol. 75, Journal of the American College of Cardiology. 2020. 7. Nunoda S. Impact of pretransplant antibodies on outcomes after heart transplantation. Vol. 24, Current Opinion in Organ Transplantation. 2019. 8. Zhu Y, Shudo Y, Lingala B, Joseph Woo Y. The impact of donor sex on heart transplantation outcomes—a study of over 60,000 patients in the United States. J Hear Lung Transplant. 2021;40(8). 9. Jawitz OK, Fudim M, Raman V, Bryner BS, DeVore AD, Mentz RJ, et al. Reassessing Recipient Mortality Under the New Heart Allocation System: An Updated UNOS Registry Analysis. JACC Hear Fail. 2020;8(7). 10. Hsich EM. Matching the market for heart transplantation. Circ Hear Fail. 2016;9(4). 11. Khush KK, Zaroff JG, Nguyen J, Menza R, Goldstein BA. National decline in donor heart utilization with regional variability: 1995-2010. Vol. 15, American Journal of Transplantation. 2015. 12. Wever Pinzon O, Stoddard G, Drakos SG, Gilbert EM, Nativi JN, Budge D, et al. Impact of donor left ventricular hypertrophy on survival after heart transplant. Am J Transplant. 2011;11(12). 13. Wood KJ, Bushell A, Hester J. Regulatory immune cells in transplantation. Vol. 12, Nature Reviews Immunology. 2012. 14. Furiasse N, Kobashigawa JA. Immunosuppression and adult heart transplantation: emerging therapies and opportunities. Vol. 15, Expert Review of Cardiovascular Therapy. 2017. 15. Virani SS, Alonso A, Benjamin EJ, Bittencourt MS, Callaway CW, Carson AP, et al. Heart disease and stroke statistics—2020 update a report from the American Heart Association. Circulation. 2020;141(9). 16. Chambers DC, Perch M, Zuckermann A, Cherikh WS, Harhay MO, HayesJr D, et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-eighth adult lung transplantation report — 2021; Focus on recipient characteristics. J Hear Lung Transplant. 2021;40(10):1060–72. 17. Samman-Tahhan A, Hedley JS, McCue AA, Bjork JB, Georgiopoulou V V., Morris AA, et al. INTERMACS Profiles and Outcomes Among Non–Inotrope-Dependent Outpatients With Heart Failure and Reduced Ejection Fraction. JACC Hear Fail. 2018;6(9). 18. Tackmann E, Dettmer S. Health-related quality of life in adult heart-transplant recipients—a systematic review. Herz. 2020;45(5). 19. Foroutan F, Alba AC, Guyatt G, Duero Posada J, Ng Fat Hing N, Arseneau E, et al. Predictors of 1-year mortality in heart transplant recipients: a systematic review and meta-analysis. Heart. 2018 Jan;104(2):151–60. 20. Alyaydin E, Welp H, Reinecke H, Tuleta I. Predisposing factors for late mortality in heart transplant patients. Cardiol J. 2021 Sep;28(5):746–57. 21. Coniglio AC, Patel CB, Kittleson M, Schlendorf K, Schroder JN, DeVore AD. Innovations in Heart Transplantation: A Review. J Card Fail. 2022 Mar;28(3):467–76. 22. Lo BD, Suarez-Pierre A, Zhou X, Lui C, Hunt MF, Whitman GJ, et al. Matchmaking Just Got Easier: Impact of Phenotypic Donor-Recipient Likeness in Heart Transplantation. Ann Thorac Surg. 2020 Jan;109(1):102–9. 23. Costanzo MR, Costanzo MR, Dipchand A, Starling R, Anderson A, Chan M, et al. The International Society of Heart and Lung Transplantation Guidelines for the care of heart transplant recipients. J Hear Lung Transplant. 2010 Aug;29(8):914–56. 24. Patel ND, Weiss ES, Nwakanma LU, Russell SD, Baumgartner WA, Shah AS, et al. Impact of Donor-to-Recipient Weight Ratio on Survival After Heart Transplantation. Circulation. 2008 Sep;118(14_suppl_1). 25. Bergenfeldt H, Lund LH, Stehlik J, Andersson B, Höglund P, Nilsson J. Time-dependent prognostic effects of recipient and donor age in adult heart transplantation. J Hear Lung Transplant. 2019;38(2):174–83. 26. Lechiancole A, Vendramin I, Sponga S, Guzzi G, Ferrara V, Nalli C, et al. Donor‐recipient age interaction and the impact on clinical results after heart transplantation. Clin Transplant. 2020 Oct;34(10). 27. Ayesta A, Urrútia G, Madrid E, Vernooij RWM, Vicent L, Martínez-Sellés M. Sex-mismatch influence on survival after heart transplantation: A systematic review and meta-analysis of observational studies. Clin Transplant. 2019;33(12). 28. Weiss ES, Allen JG, Patel ND, Russell SD, Baumgartner WA, Shah AS, et al. The Impact of Donor-Recipient Sex Matching on Survival After Orthotopic Heart Transplantation. Circ Hear Fail. 2009 Sep;2(5):401–8. 29. Bergenfeldt H, Stehlik J, Höglund P, Andersson B, Nilsson J. Donor–recipient size matching and mortality in heart transplantation: Influence of body mass index and gender. J Hear Lung Transplant [Internet]. 2017;36(9):940–7. Available from: http://dx.doi.org/10.1016/j.healun.2017.02.002 30. Rudasill SE, Sanaiha Y, Mardock AL, Xing H, Khoury H, Kwon M, et al. Height mismatch: An overlooked component of adult heart transplant outcomes. Clin Transplant. 2020 Jun;34(6). 31. Bluemke DA, Kronmal RA, Lima JAC, Liu K, Olson J, Burke GL, et al. The Relationship of Left Ventricular Mass and Geometry to Incident Cardiovascular Events. J Am Coll Cardiol. 2008 Dec;52(25):2148–55. 32. Kawut SM, Lima JAC, Barr RG, Chahal H, Jain A, Tandri H, et al. Sex and Race Differences in Right Ventricular Structure and Function. Circulation. 2011 Jun;123(22):2542–51. 33. Cheshire C, Quigley R, Claydon S, Von Joel S, Osman M, Kaul P, et al. Validation of predicted heart mass equations by measurement of donor heart mass at time of heart transplantation. Clin Transplant. 2022 Aug;36(8):1–4. 34. Kransdorf EP, Kittleson MM, Benck LR, Patel JK, Chung JS, Esmailian F, et al. Predicted heart mass is the optimal metric for size match in heart transplantation. J Hear Lung Transplant [Internet]. 2019;38(2):156–65. Available from: https://doi.org/10.1016/j.healun.2018.09.017 35. Cheshire C, Kydd A, Nerlekar N, Catarino P, Brown A, Parameshwar J, et al. Size matching in heart transplantation: Is predicted heart mass the optimal method in a United Kingdom cohort? Clin Transplant. 2021;35(3):1–10. 36. Miller RJH, Hedman K, Amsallem M, Tulu Z, Kent W, Fatehi-Hassanabad A, et al. Donor and Recipient Size Matching in Heart Transplantation With Predicted Heart and Lean Body Mass. Semin Thorac Cardiovasc Surg. 2022;34(1):158–67. 37. Santabárbara, J., López, R., Aranda, E. R., Lobo, E., & Aragüés GM. Calculo del tamaño de la muestra e estudios biomédicos. 2015. 38. Colvin M, Smith JM, Ahn Y, Skeans MA, Messick E, Bradbrook K, et al. OPTN/SRTR 2020 Annual Data Report: Heart. Am J Transplant [Internet]. 2022;22(S2):350–437. Available from: https://doi.org/10.1111/ajt.16977 39. Reed RM, Netzer G, Hunsicker L, Mitchell BD, Rajagopal K, Scharf S, et al. Cardiac Size and Sex Matching in Heart Transplantation: Size Matters in Matters of Sex and the Heart. 2014; 40. Khush KK, Cherikh WS, Chambers DC, Harhay MO, Hayes D, Hsich E, et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-sixth adult heart transplantation report — 2019; focus theme: Donor and recipient size match. J Hear Lung Transplant [Internet]. 2019;38(10):1056–66. Available from: https://doi.org/10.1016/j.healun.2019.08.004 41. Ródenas-Alesina E, Foroutan F, Fan CP, Stehlik J, Bartlett I, Tremblay-Gravel M, et al. Predicted Heart Mass: A Tale of 2 Ventricles. Circ Hear Fail. 2023;16(9). 42. Yoon M, Oh J, Lee CJ, Park JJ, Cho HJ, Choi JO, et al. Impact of predicted heart mass-based size matching on survival after heart transplantation in Korea: Analysis of the Korean Organ Transplant Registry. J Hear Lung Transplant. 2022;41(12). 43. Fukushima N, Gundry SR, Razzouk AJ, Bailey LL. Growth of oversized grafts in neonatal heart transplantation. Ann Thorac Surg. 1995;60(6). 44. Kanani M, Hoskote A, Carter C, Burch M, Tsang V, Kostolny M. Increasing donor-recipient weight mismatch in pediatric orthotopic heart transplantation does not adversely affect outcome. Eur J Cardio-thoracic Surg. 2012;41(2). 45. Jayarajan SN, Taghavi S, Komaroff E, Mangi AA. Impact of low donor to recipient weight ratios on cardiac transplantation. J Thorac Cardiovasc Surg. 2013;146(6). 46. Goldstein BA, Thomas L, Zaroff JG, Nguyen J, Menza R, Khush KK. Assessment of heart transplant waitlist time and pre- and post-transplant failure: A mixed methods approach. Epidemiology. 2016;27(4).Stehlik J, Kobashigawa J, Hunt SA, Reichenspurner H, Kirklin JK. Honoring 50 Years of Clinical Heart Transplantation in Circulation . Circulation. 2018;137(1).McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Böhm M, et al. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Vol. 42, European Heart Journal. 2021.McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Böhm M, et al. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Vol. 42, European Heart Journal. 2021.Velleca A, Shullo MA, Dhital K, Lyster H, Zdenka R. The international Society for Heart and Lung Transplantation (ISHLT) guidelines for the care of heart transplant recipients. J Hear Lung Transplant. 2022;42(5):E1–141.Guglin M, Zucker MJ, Borlaug BA, Breen E, Cleveland J, Johnson MR, et al. Evaluation for Heart Transplantation and LVAD Implantation: JACC Council Perspectives. Vol. 75, Journal of the American College of Cardiology. 2020.Nunoda S. Impact of pretransplant antibodies on outcomes after heart transplantation. Vol. 24, Current Opinion in Organ Transplantation. 2019.Zhu Y, Shudo Y, Lingala B, Joseph Woo Y. The impact of donor sex on heart transplantation outcomes—a study of over 60,000 patients in the United States. J Hear Lung Transplant. 2021;40(8).Jawitz OK, Fudim M, Raman V, Bryner BS, DeVore AD, Mentz RJ, et al. Reassessing Recipient Mortality Under the New Heart Allocation System: An Updated UNOS Registry Analysis. JACC Hear Fail. 2020;8(7).Hsich EM. Matching the market for heart transplantation. Circ Hear Fail. 2016;9(4).Khush KK, Zaroff JG, Nguyen J, Menza R, Goldstein BA. National decline in donor heart utilization with regional variability: 1995-2010. Vol. 15, American Journal of Transplantation. 2015.Wever Pinzon O, Stoddard G, Drakos SG, Gilbert EM, Nativi JN, Budge D, et al. Impact of donor left ventricular hypertrophy on survival after heart transplant. Am J Transplant. 2011;11(12).Wood KJ, Bushell A, Hester J. Regulatory immune cells in transplantation. Vol. 12, Nature Reviews Immunology. 2012.Furiasse N, Kobashigawa JA. Immunosuppression and adult heart transplantation: emerging therapies and opportunities. Vol. 15, Expert Review of Cardiovascular Therapy. 2017.Virani SS, Alonso A, Benjamin EJ, Bittencourt MS, Callaway CW, Carson AP, et al. Heart disease and stroke statistics—2020 update a report from the American Heart Association. Circulation. 2020;141(9).Chambers DC, Perch M, Zuckermann A, Cherikh WS, Harhay MO, HayesJr D, et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-eighth adult lung transplantation report — 2021; Focus on recipient characteristics. J Hear Lung Transplant. 2021;40(10):1060–72.Samman-Tahhan A, Hedley JS, McCue AA, Bjork JB, Georgiopoulou V V., Morris AA, et al. INTERMACS Profiles and Outcomes Among Non–Inotrope-Dependent Outpatients With Heart Failure and Reduced Ejection Fraction. JACC Hear Fail. 2018;6(9).Tackmann E, Dettmer S. Health-related quality of life in adult heart-transplant recipients—a systematic review. Herz. 2020;45(5).Foroutan F, Alba AC, Guyatt G, Duero Posada J, Ng Fat Hing N, Arseneau E, et al. Predictors of 1-year mortality in heart transplant recipients: a systematic review and meta-analysis. Heart. 2018 Jan;104(2):151–60.Alyaydin E, Welp H, Reinecke H, Tuleta I. Predisposing factors for late mortality in heart transplant patients. Cardiol J. 2021 Sep;28(5):746–57.Coniglio AC, Patel CB, Kittleson M, Schlendorf K, Schroder JN, DeVore AD. Innovations in Heart Transplantation: A Review. J Card Fail. 2022 Mar;28(3):467–76.Lo BD, Suarez-Pierre A, Zhou X, Lui C, Hunt MF, Whitman GJ, et al. Matchmaking Just Got Easier: Impact of Phenotypic Donor-Recipient Likeness in Heart Transplantation. Ann Thorac Surg. 2020 Jan;109(1):102–9.Costanzo MR, Costanzo MR, Dipchand A, Starling R, Anderson A, Chan M, et al. The International Society of Heart and Lung Transplantation Guidelines for the care of heart transplant recipients. J Hear Lung Transplant. 2010 Aug;29(8):914–56.Patel ND, Weiss ES, Nwakanma LU, Russell SD, Baumgartner WA, Shah AS, et al. Impact of Donor-to-Recipient Weight Ratio on Survival After Heart Transplantation. Circulation. 2008 Sep;118(14_suppl_1).Bergenfeldt H, Lund LH, Stehlik J, Andersson B, Höglund P, Nilsson J. Time-dependent prognostic effects of recipient and donor age in adult heart transplantation. J Hear Lung Transplant. 2019;38(2):174–83.Lechiancole A, Vendramin I, Sponga S, Guzzi G, Ferrara V, Nalli C, et al. Donor‐recipient age interaction and the impact on clinical results after heart transplantation. Clin Transplant. 2020 Oct;34(10).Ayesta A, Urrútia G, Madrid E, Vernooij RWM, Vicent L, Martínez-Sellés M. Sex-mismatch influence on survival after heart transplantation: A systematic review and meta-analysis of observational studies. Clin Transplant. 2019;33(12).Weiss ES, Allen JG, Patel ND, Russell SD, Baumgartner WA, Shah AS, et al. The Impact of Donor-Recipient Sex Matching on Survival After Orthotopic Heart Transplantation. Circ Hear Fail. 2009 Sep;2(5):401–8.Bergenfeldt H, Stehlik J, Höglund P, Andersson B, Nilsson J. Donor–recipient size matching and mortality in heart transplantation: Influence of body mass index and gender. J Hear Lung Transplant [Internet]. 2017;36(9):940–7. Available from: http://dx.doi.org/10.1016/j.healun.2017.02.002Rudasill SE, Sanaiha Y, Mardock AL, Xing H, Khoury H, Kwon M, et al. Height mismatch: An overlooked component of adult heart transplant outcomes. Clin Transplant. 2020 Jun;34(6).Bluemke DA, Kronmal RA, Lima JAC, Liu K, Olson J, Burke GL, et al. The Relationship of Left Ventricular Mass and Geometry to Incident Cardiovascular Events. J Am Coll Cardiol. 2008 Dec;52(25):2148–55.Kawut SM, Lima JAC, Barr RG, Chahal H, Jain A, Tandri H, et al. Sex and Race Differences in Right Ventricular Structure and Function. Circulation. 2011 Jun;123(22):2542–51.Cheshire C, Quigley R, Claydon S, Von Joel S, Osman M, Kaul P, et al. Validation of predicted heart mass equations by measurement of donor heart mass at time of heart transplantation. Clin Transplant. 2022 Aug;36(8):1–4.Kransdorf EP, Kittleson MM, Benck LR, Patel JK, Chung JS, Esmailian F, et al. Predicted heart mass is the optimal metric for size match in heart transplantation. J Hear Lung Transplant [Internet]. 2019;38(2):156–65. Available from: https://doi.org/10.1016/j.healun.2018.09.017Cheshire C, Kydd A, Nerlekar N, Catarino P, Brown A, Parameshwar J, et al. Size matching in heart transplantation: Is predicted heart mass the optimal method in a United Kingdom cohort? Clin Transplant. 2021;35(3):1–10.Miller RJH, Hedman K, Amsallem M, Tulu Z, Kent W, Fatehi-Hassanabad A, et al. Donor and Recipient Size Matching in Heart Transplantation With Predicted Heart and Lean Body Mass. Semin Thorac Cardiovasc Surg. 2022;34(1):158–67.Santabárbara, J., López, R., Aranda, E. R., Lobo, E., & Aragüés GM. Calculo del tamaño de la muestra e estudios biomédicos. 2015.Colvin M, Smith JM, Ahn Y, Skeans MA, Messick E, Bradbrook K, et al. OPTN/SRTR 2020 Annual Data Report: Heart. Am J Transplant [Internet]. 2022;22(S2):350–437. Available from: https://doi.org/10.1111/ajt.16977Reed RM, Netzer G, Hunsicker L, Mitchell BD, Rajagopal K, Scharf S, et al. Cardiac Size and Sex Matching in Heart Transplantation: Size Matters in Matters of Sex and the Heart. 2014;Khush KK, Cherikh WS, Chambers DC, Harhay MO, Hayes D, Hsich E, et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-sixth adult heart transplantation report — 2019; focus theme: Donor and recipient size match. J Hear Lung Transplant [Internet]. 2019;38(10):1056–66. Available from: https://doi.org/10.1016/j.healun.2019.08.004Ródenas-Alesina E, Foroutan F, Fan CP, Stehlik J, Bartlett I, Tremblay-Gravel M, et al. Predicted Heart Mass: A Tale of 2 Ventricles. Circ Hear Fail. 2023;16(9).Yoon M, Oh J, Lee CJ, Park JJ, Cho HJ, Choi JO, et al. Impact of predicted heart mass-based size matching on survival after heart transplantation in Korea: Analysis of the Korean Organ Transplant Registry. J Hear Lung Transplant. 2022;41(12).Fukushima N, Gundry SR, Razzouk AJ, Bailey LL. Growth of oversized grafts in neonatal heart transplantation. Ann Thorac Surg. 1995;60(6).Kanani M, Hoskote A, Carter C, Burch M, Tsang V, Kostolny M. Increasing donor-recipient weight mismatch in pediatric orthotopic heart transplantation does not adversely affect outcome. Eur J Cardio-thoracic Surg. 2012;41(2).Jayarajan SN, Taghavi S, Komaroff E, Mangi AA. Impact of low donor to recipient weight ratios on cardiac transplantation. J Thorac Cardiovasc Surg. 2013;146(6).Martinod E, Soubrane O, van Glabeke E, Drouin S, Barrou B, Zarzavadjian Le Bihan A, et al. History of first transplantations: Nothing is ever written. Part II. J Visc Surg. 2021;158(5). 2. Stehlik J, Kobashigawa J, Hunt SA, Reichenspurner H, Kirklin JK. Honoring 50 Years of Clinical Heart Transplantation in Circulation . Circulation. 2018;137(1). 3. McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Böhm M, et al. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Vol. 42, European Heart Journal. 2021. 4. Nino-Murcia A, Pinto Ramirez JL, Nino-Torres L. Organ transplantation in Colombia. Transplantation. 2018;102(11). 5. Velleca A, Shullo MA, Dhital K, Lyster H, Zdenka R. The international Society for Heart and Lung Transplantation (ISHLT) guidelines for the care of heart transplant recipients. J Hear Lung Transplant. 2022;42(5):E1–141. 6. Guglin M, Zucker MJ, Borlaug BA, Breen E, Cleveland J, Johnson MR, et al. Evaluation for Heart Transplantation and LVAD Implantation: JACC Council Perspectives. Vol. 75, Journal of the American College of Cardiology. 2020. 7. Nunoda S. Impact of pretransplant antibodies on outcomes after heart transplantation. Vol. 24, Current Opinion in Organ Transplantation. 2019. 8. Zhu Y, Shudo Y, Lingala B, Joseph Woo Y. The impact of donor sex on heart transplantation outcomes—a study of over 60,000 patients in the United States. J Hear Lung Transplant. 2021;40(8). 9. Jawitz OK, Fudim M, Raman V, Bryner BS, DeVore AD, Mentz RJ, et al. Reassessing Recipient Mortality Under the New Heart Allocation System: An Updated UNOS Registry Analysis. JACC Hear Fail. 2020;8(7). 10. Hsich EM. Matching the market for heart transplantation. Circ Hear Fail. 2016;9(4). 11. Khush KK, Zaroff JG, Nguyen J, Menza R, Goldstein BA. National decline in donor heart utilization with regional variability: 1995-2010. Vol. 15, American Journal of Transplantation. 2015. 12. Wever Pinzon O, Stoddard G, Drakos SG, Gilbert EM, Nativi JN, Budge D, et al. Impact of donor left ventricular hypertrophy on survival after heart transplant. Am J Transplant. 2011;11(12). 13. Wood KJ, Bushell A, Hester J. Regulatory immune cells in transplantation. Vol. 12, Nature Reviews Immunology. 2012. 14. Furiasse N, Kobashigawa JA. Immunosuppression and adult heart transplantation: emerging therapies and opportunities. Vol. 15, Expert Review of Cardiovascular Therapy. 2017. 15. Virani SS, Alonso A, Benjamin EJ, Bittencourt MS, Callaway CW, Carson AP, et al. Heart disease and stroke statistics—2020 update a report from the American Heart Association. Circulation. 2020;141(9). 16. Chambers DC, Perch M, Zuckermann A, Cherikh WS, Harhay MO, HayesJr D, et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-eighth adult lung transplantation report — 2021; Focus on recipient characteristics. J Hear Lung Transplant. 2021;40(10):1060–72. 17. Samman-Tahhan A, Hedley JS, McCue AA, Bjork JB, Georgiopoulou V V., Morris AA, et al. INTERMACS Profiles and Outcomes Among Non–Inotrope-Dependent Outpatients With Heart Failure and Reduced Ejection Fraction. JACC Hear Fail. 2018;6(9). 18. Tackmann E, Dettmer S. Health-related quality of life in adult heart-transplant recipients—a systematic review. Herz. 2020;45(5). 19. Foroutan F, Alba AC, Guyatt G, Duero Posada J, Ng Fat Hing N, Arseneau E, et al. Predictors of 1-year mortality in heart transplant recipients: a systematic review and meta-analysis. Heart. 2018 Jan;104(2):151–60. 20. Alyaydin E, Welp H, Reinecke H, Tuleta I. Predisposing factors for late mortality in heart transplant patients. Cardiol J. 2021 Sep;28(5):746–57. 21. Coniglio AC, Patel CB, Kittleson M, Schlendorf K, Schroder JN, DeVore AD. Innovations in Heart Transplantation: A Review. J Card Fail. 2022 Mar;28(3):467–76. 22. Lo BD, Suarez-Pierre A, Zhou X, Lui C, Hunt MF, Whitman GJ, et al. Matchmaking Just Got Easier: Impact of Phenotypic Donor-Recipient Likeness in Heart Transplantation. Ann Thorac Surg. 2020 Jan;109(1):102–9. 23. Costanzo MR, Costanzo MR, Dipchand A, Starling R, Anderson A, Chan M, et al. The International Society of Heart and Lung Transplantation Guidelines for the care of heart transplant recipients. J Hear Lung Transplant. 2010 Aug;29(8):914–56. 24. Patel ND, Weiss ES, Nwakanma LU, Russell SD, Baumgartner WA, Shah AS, et al. Impact of Donor-to-Recipient Weight Ratio on Survival After Heart Transplantation. Circulation. 2008 Sep;118(14_suppl_1). 25. Bergenfeldt H, Lund LH, Stehlik J, Andersson B, Höglund P, Nilsson J. Time-dependent prognostic effects of recipient and donor age in adult heart transplantation. J Hear Lung Transplant. 2019;38(2):174–83. 26. Lechiancole A, Vendramin I, Sponga S, Guzzi G, Ferrara V, Nalli C, et al. Donor‐recipient age interaction and the impact on clinical results after heart transplantation. Clin Transplant. 2020 Oct;34(10). 27. Ayesta A, Urrútia G, Madrid E, Vernooij RWM, Vicent L, Martínez-Sellés M. Sex-mismatch influence on survival after heart transplantation: A systematic review and meta-analysis of observational studies. Clin Transplant. 2019;33(12). 28. Weiss ES, Allen JG, Patel ND, Russell SD, Baumgartner WA, Shah AS, et al. The Impact of Donor-Recipient Sex Matching on Survival After Orthotopic Heart Transplantation. Circ Hear Fail. 2009 Sep;2(5):401–8. 29. Bergenfeldt H, Stehlik J, Höglund P, Andersson B, Nilsson J. Donor–recipient size matching and mortality in heart transplantation: Influence of body mass index and gender. J Hear Lung Transplant [Internet]. 2017;36(9):940–7. Available from: http://dx.doi.org/10.1016/j.healun.2017.02.002 30. Rudasill SE, Sanaiha Y, Mardock AL, Xing H, Khoury H, Kwon M, et al. Height mismatch: An overlooked component of adult heart transplant outcomes. Clin Transplant. 2020 Jun;34(6). 31. Bluemke DA, Kronmal RA, Lima JAC, Liu K, Olson J, Burke GL, et al. The Relationship of Left Ventricular Mass and Geometry to Incident Cardiovascular Events. J Am Coll Cardiol. 2008 Dec;52(25):2148–55. 32. Kawut SM, Lima JAC, Barr RG, Chahal H, Jain A, Tandri H, et al. Sex and Race Differences in Right Ventricular Structure and Function. Circulation. 2011 Jun;123(22):2542–51. 33. Cheshire C, Quigley R, Claydon S, Von Joel S, Osman M, Kaul P, et al. Validation of predicted heart mass equations by measurement of donor heart mass at time of heart transplantation. Clin Transplant. 2022 Aug;36(8):1–4. 34. Kransdorf EP, Kittleson MM, Benck LR, Patel JK, Chung JS, Esmailian F, et al. Predicted heart mass is the optimal metric for size match in heart transplantation. J Hear Lung Transplant [Internet]. 2019;38(2):156–65. Available from: https://doi.org/10.1016/j.healun.2018.09.017 35. Cheshire C, Kydd A, Nerlekar N, Catarino P, Brown A, Parameshwar J, et al. Size matching in heart transplantation: Is predicted heart mass the optimal method in a United Kingdom cohort? Clin Transplant. 2021;35(3):1–10. 36. Miller RJH, Hedman K, Amsallem M, Tulu Z, Kent W, Fatehi-Hassanabad A, et al. Donor and Recipient Size Matching in Heart Transplantation With Predicted Heart and Lean Body Mass. Semin Thorac Cardiovasc Surg. 2022;34(1):158–67. 37. Santabárbara, J., López, R., Aranda, E. R., Lobo, E., & Aragüés GM. Calculo del tamaño de la muestra e estudios biomédicos. 2015. 38. Colvin M, Smith JM, Ahn Y, Skeans MA, Messick E, Bradbrook K, et al. OPTN/SRTR 2020 Annual Data Report: Heart. Am J Transplant [Internet]. 2022;22(S2):350–437. Available from: https://doi.org/10.1111/ajt.16977 39. Reed RM, Netzer G, Hunsicker L, Mitchell BD, Rajagopal K, Scharf S, et al. Cardiac Size and Sex Matching in Heart Transplantation: Size Matters in Matters of Sex and the Heart. 2014; 40. Khush KK, Cherikh WS, Chambers DC, Harhay MO, Hayes D, Hsich E, et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-sixth adult heart transplantation report — 2019; focus theme: Donor and recipient size match. J Hear Lung Transplant [Internet]. 2019;38(10):1056–66. Available from: https://doi.org/10.1016/j.healun.2019.08.004 41. Ródenas-Alesina E, Foroutan F, Fan CP, Stehlik J, Bartlett I, Tremblay-Gravel M, et al. Predicted Heart Mass: A Tale of 2 Ventricles. Circ Hear Fail. 2023;16(9). 42. Yoon M, Oh J, Lee CJ, Park JJ, Cho HJ, Choi JO, et al. Impact of predicted heart mass-based size matching on survival after heart transplantation in Korea: Analysis of the Korean Organ Transplant Registry. J Hear Lung Transplant. 2022;41(12). 43. Fukushima N, Gundry SR, Razzouk AJ, Bailey LL. Growth of oversized grafts in neonatal heart transplantation. Ann Thorac Surg. 1995;60(6). 44. Kanani M, Hoskote A, Carter C, Burch M, Tsang V, Kostolny M. Increasing donor-recipient weight mismatch in pediatric orthotopic heart transplantation does not adversely affect outcome. Eur J Cardio-thoracic Surg. 2012;41(2). 45. Jayarajan SN, Taghavi S, Komaroff E, Mangi AA. Impact of low donor to recipient weight ratios on cardiac transplantation. J Thorac Cardiovasc Surg. 2013;146(6). 46. Goldstein BA, Thomas L, Zaroff JG, Nguyen J, Menza R, Khush KK. Assessment of heart transplant waitlist time and pre- and post-transplant failure: A mixed methods approach. 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