Inferring Plasmodium vivax protein biology by using omics data

Deciphering Plasmodium vivax biology has long been a challenge for groups working on this parasite, mainly due to the complications involved in propagating it in vitro. However, adapting P. vivax strains in non-human primates and the arrival of high-performance analysis methods has led to increased knowledge regarding parasite protein composition and the ability of some molecules to trigger an immune response or participate in protein-protein interactions. This review describes the state of the art concerning proteomics-, immunomics- and interatomics-related P. vivax omic studies, discussing their potential use in developing disease control methods. © 2020 The Authors

• Fecha de publicación: 2020
• Institución: Universidad del Rosario
• Repositorio: Repositorio EdocUR - U. Rosario
• Idioma: eng
• OAI Identifier: oai:repository.urosario.edu.co:10336/22440
• Acceso en línea: https://doi.org/10.1016/j.jprot.2020.103719; https://repository.urosario.edu.co/handle/10336/22440
• Palabra clave: Microorganism protein; Disease control; Immunomics; Interactomics; Nonhuman; Omics; Plasmodium vivax; Priority journal; Protein analysis; Protein protein interaction; Proteomics; Review; Control methods; Immunomics; Interactomics; Plasmodium vivax; Proteomics
• License: Abierto (Texto Completo)