First Girgensohnine Analogs Prepared Through InCl3-catalyzed Strecker Reaction and their Bioprospection

An efficient preparation of the girgensohnine and its close analogs with α-aminonitrile structure, and their spectral characterization were reported for the first time. The piperidine α-aminonitriles were obtained through 5 mol% InCl3-catalyzed one-pot Strecker reaction and tested for antioxidant ac...

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Autores:
Tipo de recurso:
Fecha de publicación:
2013
Institución:
Ministerio de Ciencia Tecnología e Innovación
Repositorio:
Repositorio Institucional de Minciencias
Idioma:
eng
OAI Identifier:
oai:repositorio.minciencias.gov.co:20.500.14143/34174
Acceso en línea:
http://repositorio.colciencias.gov.co/handle/11146/34174
Palabra clave:
Biología vegetal
Productos químicos
Aceites vegetales
AChE inhibitory activity
Alkaloids
α-Aminonitriles
Antioxidant capacity
Girgensohnine
Strecker reaction
Aceites esenciales
Bioquímica vegetal
Biotecnología
Catalizadores
Rights
License
http://purl.org/coar/access_right/c_f1cf
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oai_identifier_str oai:repositorio.minciencias.gov.co:20.500.14143/34174
network_acronym_str E-ANAQUEL2
network_name_str Repositorio Institucional de Minciencias
repository_id_str
spelling First Girgensohnine Analogs Prepared Through InCl3-catalyzed Strecker Reaction and their BioprospectionBiología vegetalProductos químicosAceites vegetalesAChE inhibitory activityAlkaloidsα-AminonitrilesAntioxidant capacityGirgensohnineStrecker reactionAceites esencialesBioquímica vegetalBiotecnologíaCatalizadoresAn efficient preparation of the girgensohnine and its close analogs with α-aminonitrile structure, and their spectral characterization were reported for the first time. The piperidine α-aminonitriles were obtained through 5 mol% InCl3-catalyzed one-pot Strecker reaction and tested for antioxidant activity and AChE inhibitory properties. It was found that girgensohnine possesses a moderate AChE inhibitory property while its spiroanalog shows good antioxidant capacityDepartamento Administrativo de Ciencia, Tecnología e Innovación [CO] Colciencias5507-543-31904Programa: Bioprospección y desarrollo de ingredientes naturales para las industrias cosmética, farmacéutica y de productos de aseo con base en la biodiversidad colombianano2019-04-01T02:42:46Z2019-04-01T02:42:46Z2013info:eu-repo/date/embargoEnd/2024-01-31Artículo científicoinfo:eu-repo/semantics/articlehttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_2df8fbb1pdf5 páginasapplication/pdf1875-6271http://repositorio.colciencias.gov.co/handle/11146/34174Contiene 26 referencias bibliográficas. Véase documento adjuntoCurrent Organic Synthesis, 2013, 10, 969-973engPrograma: Bioprospección y desarrollo de ingredientes naturales para las industrias cosmética, farmacéutica y de productos de aseo con base en la biodiversidad colombiana. La publicación completa está disponible en : <a href="http://repositorio.colciencias.gov.co/handle/11146/34163" target="blank">http://repositorio.colciencias.gov.co/handle/11146/34163</a>Colombiahttp://purl.org/coar/access_right/c_f1cfVargas Méndez, Leonor YamileKouznetsov, Vladimir V.oai:repositorio.minciencias.gov.co:20.500.14143/341742023-11-29T17:46:38Z
dc.title.none.fl_str_mv First Girgensohnine Analogs Prepared Through InCl3-catalyzed Strecker Reaction and their Bioprospection
title First Girgensohnine Analogs Prepared Through InCl3-catalyzed Strecker Reaction and their Bioprospection
spellingShingle First Girgensohnine Analogs Prepared Through InCl3-catalyzed Strecker Reaction and their Bioprospection
Biología vegetal
Productos químicos
Aceites vegetales
AChE inhibitory activity
Alkaloids
α-Aminonitriles
Antioxidant capacity
Girgensohnine
Strecker reaction
Aceites esenciales
Bioquímica vegetal
Biotecnología
Catalizadores
title_short First Girgensohnine Analogs Prepared Through InCl3-catalyzed Strecker Reaction and their Bioprospection
title_full First Girgensohnine Analogs Prepared Through InCl3-catalyzed Strecker Reaction and their Bioprospection
title_fullStr First Girgensohnine Analogs Prepared Through InCl3-catalyzed Strecker Reaction and their Bioprospection
title_full_unstemmed First Girgensohnine Analogs Prepared Through InCl3-catalyzed Strecker Reaction and their Bioprospection
title_sort First Girgensohnine Analogs Prepared Through InCl3-catalyzed Strecker Reaction and their Bioprospection
dc.subject.none.fl_str_mv Biología vegetal
Productos químicos
Aceites vegetales
AChE inhibitory activity
Alkaloids
α-Aminonitriles
Antioxidant capacity
Girgensohnine
Strecker reaction
Aceites esenciales
Bioquímica vegetal
Biotecnología
Catalizadores
topic Biología vegetal
Productos químicos
Aceites vegetales
AChE inhibitory activity
Alkaloids
α-Aminonitriles
Antioxidant capacity
Girgensohnine
Strecker reaction
Aceites esenciales
Bioquímica vegetal
Biotecnología
Catalizadores
description An efficient preparation of the girgensohnine and its close analogs with α-aminonitrile structure, and their spectral characterization were reported for the first time. The piperidine α-aminonitriles were obtained through 5 mol% InCl3-catalyzed one-pot Strecker reaction and tested for antioxidant activity and AChE inhibitory properties. It was found that girgensohnine possesses a moderate AChE inhibitory property while its spiroanalog shows good antioxidant capacity
publishDate 2013
dc.date.none.fl_str_mv 2013
2019-04-01T02:42:46Z
2019-04-01T02:42:46Z
info:eu-repo/date/embargoEnd/2024-01-31
dc.type.none.fl_str_mv Artículo científico
info:eu-repo/semantics/article
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
dc.identifier.none.fl_str_mv 1875-6271
http://repositorio.colciencias.gov.co/handle/11146/34174
Contiene 26 referencias bibliográficas. Véase documento adjunto
identifier_str_mv 1875-6271
Contiene 26 referencias bibliográficas. Véase documento adjunto
url http://repositorio.colciencias.gov.co/handle/11146/34174
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Programa: Bioprospección y desarrollo de ingredientes naturales para las industrias cosmética, farmacéutica y de productos de aseo con base en la biodiversidad colombiana. La publicación completa está disponible en : <a href="http://repositorio.colciencias.gov.co/handle/11146/34163" target="blank">http://repositorio.colciencias.gov.co/handle/11146/34163</a>
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_f1cf
rights_invalid_str_mv http://purl.org/coar/access_right/c_f1cf
dc.format.none.fl_str_mv pdf
5 páginas
application/pdf
dc.coverage.none.fl_str_mv Colombia
dc.source.none.fl_str_mv Current Organic Synthesis, 2013, 10, 969-973
institution Ministerio de Ciencia Tecnología e Innovación
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1860676510633951232

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