Mutations of the CHEK2 gene in patients with cancer and their presence in the Latin American population
Background: CHEK2 (Checkpoint Kinase 2) encodes CHK2, a serine/threonine kinase involved in maintaining the G1/S and G2/M checkpoints and repair of double-strand DNA breaks via homologous recombination. Functions of CHK2 include the prevention of damaged
- Autores:
-
Guauque Olarte, Sandra milena
Cifuentes Cardona, Laura Fernanda
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2023
- Institución:
- Universidad Cooperativa de Colombia
- Repositorio:
- Repositorio UCC
- Idioma:
- OAI Identifier:
- oai:repository.ucc.edu.co:20.500.12494/50238
- Acceso en línea:
- https://doi.org/10.12688/f1000research.9932.1
https://hdl.handle.net/20.500.12494/50238
- Palabra clave:
- CANCER
CHEK2
CHEK2*1100DELC
CHK2
DATABASES
GENOMICS.
LATIN AMERICA
MUTATIONS
- Rights
- openAccess
- License
- http://purl.org/coar/access_right/c_abf2
| Summary: | Background: CHEK2 (Checkpoint Kinase 2) encodes CHK2, a serine/threonine kinase involved in maintaining the G1/S and G2/M checkpoints and repair of double-strand DNA breaks via homologous recombination. Functions of CHK2 include the prevention of damaged |
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