Thermodynamic analysis of the solubility of propranolol-HCl in ethanol + water mixtures

Propranolol-HCl (PPN-HCl) is a non selective ?-adrenergic blocker widely used in therapeutics. Nevertheless, their physicochemical properties in aqueous media have not been adequately studied. In this context, by using the van't Hoff and Gibbs equations t

Autores:
Delgado, Daniel Ricardo
Martínez Rodríguez, Fleming
Tipo de recurso:
Article of journal
Fecha de publicación:
2010
Institución:
Universidad Cooperativa de Colombia
Repositorio:
Repositorio UCC
Idioma:
OAI Identifier:
oai:repository.ucc.edu.co:20.500.12494/42981
Acceso en línea:
https://sedici.unlp.edu.ar/handle/10915/8105
https://hdl.handle.net/20.500.12494/42981
Palabra clave:
Solubilidad
cosolvency
ethanol
solubility
solution thermodynamics
propranolol-HCl
Alcoholes
Termodinámica
Rights
closedAccess
License
http://purl.org/coar/access_right/c_14cb
Description
Summary:Propranolol-HCl (PPN-HCl) is a non selective ?-adrenergic blocker widely used in therapeutics. Nevertheless, their physicochemical properties in aqueous media have not been adequately studied. In this context, by using the van't Hoff and Gibbs equations t