Geometrical study of astrocytomas through fractals and scaling analysis
The tumor growth is a complex process characterized by the proliferation of uncontrollable cells which invade neighbor tissues. The understanding process of this type of phenomena is very relevant in order to establish diagnosis and proper therapy strategies and to start the valorization of its comp...
- Autores:
-
Torres Hoyos, Francisco José
Baena Navarro, Rubén Enrique
Vergara Villadiego, Juan
Guerrero Martelo, Manuel Francisco
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2023
- Institución:
- Universidad Cooperativa de Colombia
- Repositorio:
- Repositorio UCC
- Idioma:
- OAI Identifier:
- oai:repository.ucc.edu.co:20.500.12494/50338
- Acceso en línea:
- https://doi.org/10.1016/j.apradiso.2018.05.020
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85047446276&doi=10.1016%2fj.apradiso.2018.05.020&partnerID=40&md5=43c14530aad2510338909c41ee0a7beb
https://hdl.handle.net/20.500.12494/50338
- Palabra clave:
- ANAPLASTIC
ARTICLE
ASTROCYTOMA
BRAIN RADIATION
BRAIN RADIOTHERAPY
BRAIN SIZE
CANCER GROWTH
CANCER STAGING
CLINICAL ARTICLE
COMPLEX PROCESSES
CONTRAST ENHANCEMENT
CONTROLLED STUDY
DIAGNOSIS
DIFFUSE
DIFFUSE ASTROCYTOMA
FRACTAL ANALYSIS
FRACTAL DIMENSION
FRACTALS
GADOLINIUM
GEOMETRY
GLIOBLASTOMA
HUMAN
IMAGE ANALYSIS
IMAGE PROCESSING
IMAGE SEGMENTATION
IN VIVO STUDY
MAGNETIC RESONANCE
MATHEMATICAL ANALYSIS
MATHEMATICAL COMPUTING
NUCLEAR MAGNETIC RESONANCE IMAGING
PILOCYTIC
PILOCYTIC ASTROCYTOMA
PRIORITY JOURNAL
RADIOSURGERY
RADIOTHERAPY
SCALING ANALYSIS
STANDARD PROTOCOLS
THERAPY STRATEGIES
THREE DIMENSIONAL IMAGING
TUMORS
WORLD HEALTH ORGANIZATION
- Rights
- openAccess
- License
- http://purl.org/coar/access_right/c_abf2
| Summary: | The tumor growth is a complex process characterized by the proliferation of uncontrollable cells which invade neighbor tissues. The understanding process of this type of phenomena is very relevant in order to establish diagnosis and proper therapy strategies and to start the valorization of its complexity with proper descriptors produced by the scaling analysis, which define the tumor growth geometry. In this work, obtained results through the scaling analysis for pilocytic astrocytomas, anaplastic and diffuse, are shown, which tumors of primary origin are. On them, it is calculated the fractal dimension and critical exponents of local roughness to characterize in vivo 3-D tumor growth. The acquisition of the images for this type of injuries was carried out according to the standard protocol used for brain radiotherapy and radiosurgery, i.e., axial, coronal and sagittal magnetic resonance T1 weighted images and comprising the brain volume for image registration. Image segmentation was performed by the application the k-means procedure upon contrasted images. The results show significant variations of the parameters depending on the tumor stage and its histological origin. © 2018 |
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