Antiviral role of phenolic compounds against dengue virus: a review
Phenolic compounds have been related to multiple biological activities, and the antiviral effect of these compounds has been demonstrated in several viral models of public health concern. In this review, we show the antiviral role of phenolic compounds against dengue virus (DENV), the most widesprea...
- Autores:
-
Loaiza Cano, Vanessa
Monsalve Escudero, Laura Milena
Martínez Gutierrez, Marlen
de Souza, Damião Pergentin
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2021
- Institución:
- Universidad Cooperativa de Colombia
- Repositorio:
- Repositorio UCC
- Idioma:
- OAI Identifier:
- oai:repository.ucc.edu.co:20.500.12494/32927
- Acceso en línea:
- https://hdl.handle.net/20.500.12494/32927
- Palabra clave:
- Natural products
Flavonoids
Tannins
Phenol
Medicinal plants
Mosquitoes
Dengue virus
Viruses
- Rights
- openAccess
- License
- Atribución – No comercial – Compartir igual
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Antiviral role of phenolic compounds against dengue virus: a review |
| title |
Antiviral role of phenolic compounds against dengue virus: a review |
| spellingShingle |
Antiviral role of phenolic compounds against dengue virus: a review Natural products Flavonoids Tannins Phenol Medicinal plants Mosquitoes Dengue virus Viruses |
| title_short |
Antiviral role of phenolic compounds against dengue virus: a review |
| title_full |
Antiviral role of phenolic compounds against dengue virus: a review |
| title_fullStr |
Antiviral role of phenolic compounds against dengue virus: a review |
| title_full_unstemmed |
Antiviral role of phenolic compounds against dengue virus: a review |
| title_sort |
Antiviral role of phenolic compounds against dengue virus: a review |
| dc.creator.fl_str_mv |
Loaiza Cano, Vanessa Monsalve Escudero, Laura Milena Martínez Gutierrez, Marlen de Souza, Damião Pergentin |
| dc.contributor.author.none.fl_str_mv |
Loaiza Cano, Vanessa Monsalve Escudero, Laura Milena Martínez Gutierrez, Marlen de Souza, Damião Pergentin |
| dc.subject.spa.fl_str_mv |
Natural products Flavonoids Tannins Phenol Medicinal plants Mosquitoes Dengue virus Viruses |
| topic |
Natural products Flavonoids Tannins Phenol Medicinal plants Mosquitoes Dengue virus Viruses |
| description |
Phenolic compounds have been related to multiple biological activities, and the antiviral effect of these compounds has been demonstrated in several viral models of public health concern. In this review, we show the antiviral role of phenolic compounds against dengue virus (DENV), the most widespread arbovirus globally that, after its re-emergence, has caused multiple epidemic outbreaks, especially in the last two years. Twenty phenolic compounds with anti-DENV activity are discussed, including the multiple mechanisms of action, such as those directed against viral particles or viral proteins, host proteins or pathways related to the productive replication viral cycle and the spread of the infection. |
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2021-01 |
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Artículos Científicos |
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Loaiza-Cano, Vanessa; Monsalve-Escudero, Laura M.; Filho, Carlos d.S.M.B.; Martinez-Gutierrez, Marlen; Sousa, Damião P.d. 2021. "Antiviral Role of Phenolic Compounds against Dengue Virus: A Review" Biomolecules 11, no. 1: 11. https://doi.org/10.3390/biom11010011 |
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2218-273X doi.org/10.3390/biom11010011 Loaiza-Cano, Vanessa; Monsalve-Escudero, Laura M.; Filho, Carlos d.S.M.B.; Martinez-Gutierrez, Marlen; Sousa, Damião P.d. 2021. "Antiviral Role of Phenolic Compounds against Dengue Virus: A Review" Biomolecules 11, no. 1: 11. https://doi.org/10.3390/biom11010011 |
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Biomolecules |
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Uno, N.; Ross, T.M. Dengue virus and the host innate immune response. Emerg. Microbes Infect. 2018, 7, 1–11 Martina, B.E.E.; Koraka, P.; Osterhaus, A.D.M.E. Dengue virus pathogenesis: An integrated view. Clin. Microbiol. Rev. 2009, 22, 564–581 Sandoval, E.; Téllez, Y.; Harris, E.; Videa, E.; Amador, J.J.; Gonzalez, A.; Pérez, L.; Campo, L.A.; Pérez, M.L.; Cuadra, R.; et al. Clinical, epidemiologic, and virologic features of dengue in the 1998 epidemic in Nicaragua. Am. J. Trop. Med. Hyg. 2000, 63, 5–11 Screaton, G.; Mongkolsapaya, J.; Yacoub, S.; Roberts, C. New insights into the immunopathology and control of dengue virus infection. Nat. Rev. Immunol. 2015, 15, 745–759 Rodríguez-Pérez, C.; Segura-Carretero, A.; del Mar Contreras, M. Phenolic compounds as natural and multifunctional anti-obesity agents: A review. Crit. Rev. Food Sci. Nutr. 2019, 59, 1212–1229. Thitilertdecha, N.; Teerawutgulrag, A.; Kilburn, J.D.; Rakariyatham, N. Identification of major Phenolic compounds from Nephelium lappaceum L. and their antioxidant activities. Molecules 2010, 15, 1453–1465. Sáez, V.; Pastene, E.; Vergara, C.; Mardones, C.; Hermosín-Gutiérrez, I.; Gómez-Alonso, S.; Gómez, M.V.; Theoduloz, C.; Riquelme, S.; von Baer, D. Oligostilbenoids in Vitis vinifera L. Pinot Noir grape cane extract: Isolation, characterization, in vitro antioxidant capacity and anti-proliferative effect on cancer cells. Food Chem. 2018, 265, 101–110. Batallán, G.; Torre, R.; Flores, F.; Konigheim, B.; Ludueña-Almeida, F.; Tonn, C.; Contigiani, M.; Almirón, W. Larvicidal activity of crude extracts from Larrea cuneifolia (Zygophyllaceae) and of its metabolite nordihydroguaiaretic acid against the vector Culex quinquefasciatus (Diptera: Culicidae). Rev. Soc. Bras. Med. Trop. 2013, 46, 84–87 Wolff, T.; Berrueta, L.A.; Valente, L.M.M.; Barboza, R.S.; Neris, R.L.S.; Guimarães-Andrade, I.P.; Assunção-Miranda, I.; Nascimento, A.C.; Gomes, M.; Gallo, B.; et al. Comprehensive characterisation of polyphenols in leaves and stems of three anti-dengue virus type-2 active Brazilian Faramea species (Rubiaceae) by HPLC-DAD-ESI-MS/MS. Phytochem. Anal. 2019, 30, 62–72 Barbieri, M.; Heard, C.M. Isolation of punicalagin from Punica granatum rind extract using mass-directed semi-preparative ESI-AP single quadrupole LC-MS. J. Pharm. Biomed. Anal. 2019, 166, 90–94 Çevik, D.; Kan, Y.; Kırmızıbekmez, H. Mechanisms of action of cytotoxic phenolic compounds from Glycyrrhiza iconica roots. Phytomedicine 2019, 58, 152872 Cianciosi, D.; Forbes-Hernández, T.; Afrin, S.; Gasparrini, M.; Reboredo-Rodriguez, P.; Manna, P.; Zhang, J.; Bravo Lamas, L.; Martínez Flórez, S.; Agudo Toyos, P.; et al. Phenolic compounds in honey and their associated health benefits: A review. Molecules 2018, 23, 2322. Xiang, J.; Apea-Bah, F.B.; Ndolo, V.U.; Katundu, M.C.; Beta, T. Profile of phenolic compounds and antioxidant activity of finger millet varieties. Food Chem. 2019, 275, 361–368 Rice-Evans, C.A.; Miller, N.J. Antioxidant activities of flavonoids as bioactive components of food. Biochem. Soc. Trans. 1996, 24, 790–795. Saud, S.M.; Li, W.; Morris, N.L.; Matter, M.S.; Colburn, N.H.; Kim, Y.S.; Young, M.R. Resveratrol prevents tumorigenesis in mouse model of Kras activated sporadic colorectal cancer by suppressing oncogenic Kras expression. Carcinogenesis 2014, 35, 2778–2786 Boakye, Y.D.; Agyare, C.; Abotsi, W.K.M.; Ayande, P.G.; Ossei, P.P.S. Anti-inflammatory activity of aqueous leaf extract of Phyllanthus muellerianus (Kuntze) Exell. and its major constituent, geraniin. J. Ethnopharmacol. 2016, 187, 17–27. Izui, S.; Sekine, S.; Maeda, K.; Kuboniwa, M.; Takada, A.; Amano, A.; Nagata, H. Antibacterial activity of curcumin against Periodontopathic bacteria. J. Periodontol. 2016, 87, 83–90 Andrade, J.T.; Fantini de Figueiredo, G.; Cruz, L.F.; Eliza de Morais, S.; Souza, C.D.F.; Pinto, F.C.H.; Ferreira, J.M.S.; de Freitas Araújo, M.G. Efficacy of curcumin in the treatment of experimental vulvovaginal candidiasis. Rev. Iberoam. Micol. 2019, 36, 192–199. Zhang, X.-L.; Guo, Y.-S.; Wang, C.-H.; Li, G.-Q.; Xu, J.-J.; Chung, H.Y.; Ye, W.-C.; Li, Y.-L.; Wang, G.-C. Phenolic compounds from Origanum vulgare and their antioxidant and antiviral activities. Food Chem. 2014, 152, 300–306. |
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Loaiza Cano, VanessaMonsalve Escudero, Laura MilenaMartínez Gutierrez, Marlende Souza, Damião Pergentin11(1)2021-01-28T16:42:35Z2021-01-28T16:42:35Z2021-012021-012218-273Xdoi.org/10.3390/biom11010011https://hdl.handle.net/20.500.12494/32927Loaiza-Cano, Vanessa; Monsalve-Escudero, Laura M.; Filho, Carlos d.S.M.B.; Martinez-Gutierrez, Marlen; Sousa, Damião P.d. 2021. "Antiviral Role of Phenolic Compounds against Dengue Virus: A Review" Biomolecules 11, no. 1: 11. https://doi.org/10.3390/biom11010011Phenolic compounds have been related to multiple biological activities, and the antiviral effect of these compounds has been demonstrated in several viral models of public health concern. In this review, we show the antiviral role of phenolic compounds against dengue virus (DENV), the most widespread arbovirus globally that, after its re-emergence, has caused multiple epidemic outbreaks, especially in the last two years. Twenty phenolic compounds with anti-DENV activity are discussed, including the multiple mechanisms of action, such as those directed against viral particles or viral proteins, host proteins or pathways related to the productive replication viral cycle and the spread of the infection.https://scienti.colciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0000213748https://orcid.org/0000-0002-9429-0058https://scienti.minciencias.gov.co/gruplac/jsp/visualiza/visualizagr.jsp?nro=00000000000695Marlen.martinezg@campucucc.edu.cohttps://scholar.google.es/citations?user=flSrsSIAAAAJ&hl=es1 p. MDPIUniversidad Cooperativa de Colombia, Facultad de Ciencias de la Salud, Medicina Veterinaría y Zootecnia, BucaramangaMedicina veterinaria y zootecniaBucaramangahttps://www.mdpi.com/2218-273X/11/1/11BiomoleculesUno, N.; Ross, T.M. Dengue virus and the host innate immune response. Emerg. Microbes Infect. 2018, 7, 1–11Martina, B.E.E.; Koraka, P.; Osterhaus, A.D.M.E. Dengue virus pathogenesis: An integrated view. Clin. Microbiol. Rev. 2009, 22, 564–581Sandoval, E.; Téllez, Y.; Harris, E.; Videa, E.; Amador, J.J.; Gonzalez, A.; Pérez, L.; Campo, L.A.; Pérez, M.L.; Cuadra, R.; et al. Clinical, epidemiologic, and virologic features of dengue in the 1998 epidemic in Nicaragua. Am. J. Trop. Med. Hyg. 2000, 63, 5–11Screaton, G.; Mongkolsapaya, J.; Yacoub, S.; Roberts, C. New insights into the immunopathology and control of dengue virus infection. Nat. Rev. Immunol. 2015, 15, 745–759Rodríguez-Pérez, C.; Segura-Carretero, A.; del Mar Contreras, M. Phenolic compounds as natural and multifunctional anti-obesity agents: A review. Crit. Rev. Food Sci. Nutr. 2019, 59, 1212–1229.Thitilertdecha, N.; Teerawutgulrag, A.; Kilburn, J.D.; Rakariyatham, N. Identification of major Phenolic compounds from Nephelium lappaceum L. and their antioxidant activities. Molecules 2010, 15, 1453–1465.Sáez, V.; Pastene, E.; Vergara, C.; Mardones, C.; Hermosín-Gutiérrez, I.; Gómez-Alonso, S.; Gómez, M.V.; Theoduloz, C.; Riquelme, S.; von Baer, D. Oligostilbenoids in Vitis vinifera L. Pinot Noir grape cane extract: Isolation, characterization, in vitro antioxidant capacity and anti-proliferative effect on cancer cells. Food Chem. 2018, 265, 101–110.Batallán, G.; Torre, R.; Flores, F.; Konigheim, B.; Ludueña-Almeida, F.; Tonn, C.; Contigiani, M.; Almirón, W. Larvicidal activity of crude extracts from Larrea cuneifolia (Zygophyllaceae) and of its metabolite nordihydroguaiaretic acid against the vector Culex quinquefasciatus (Diptera: Culicidae). Rev. Soc. Bras. Med. Trop. 2013, 46, 84–87Wolff, T.; Berrueta, L.A.; Valente, L.M.M.; Barboza, R.S.; Neris, R.L.S.; Guimarães-Andrade, I.P.; Assunção-Miranda, I.; Nascimento, A.C.; Gomes, M.; Gallo, B.; et al. Comprehensive characterisation of polyphenols in leaves and stems of three anti-dengue virus type-2 active Brazilian Faramea species (Rubiaceae) by HPLC-DAD-ESI-MS/MS. Phytochem. Anal. 2019, 30, 62–72Barbieri, M.; Heard, C.M. Isolation of punicalagin from Punica granatum rind extract using mass-directed semi-preparative ESI-AP single quadrupole LC-MS. J. Pharm. Biomed. Anal. 2019, 166, 90–94Çevik, D.; Kan, Y.; Kırmızıbekmez, H. Mechanisms of action of cytotoxic phenolic compounds from Glycyrrhiza iconica roots. Phytomedicine 2019, 58, 152872Cianciosi, D.; Forbes-Hernández, T.; Afrin, S.; Gasparrini, M.; Reboredo-Rodriguez, P.; Manna, P.; Zhang, J.; Bravo Lamas, L.; Martínez Flórez, S.; Agudo Toyos, P.; et al. Phenolic compounds in honey and their associated health benefits: A review. Molecules 2018, 23, 2322.Xiang, J.; Apea-Bah, F.B.; Ndolo, V.U.; Katundu, M.C.; Beta, T. Profile of phenolic compounds and antioxidant activity of finger millet varieties. Food Chem. 2019, 275, 361–368Rice-Evans, C.A.; Miller, N.J. Antioxidant activities of flavonoids as bioactive components of food. Biochem. Soc. Trans. 1996, 24, 790–795.Saud, S.M.; Li, W.; Morris, N.L.; Matter, M.S.; Colburn, N.H.; Kim, Y.S.; Young, M.R. Resveratrol prevents tumorigenesis in mouse model of Kras activated sporadic colorectal cancer by suppressing oncogenic Kras expression. Carcinogenesis 2014, 35, 2778–2786Boakye, Y.D.; Agyare, C.; Abotsi, W.K.M.; Ayande, P.G.; Ossei, P.P.S. Anti-inflammatory activity of aqueous leaf extract of Phyllanthus muellerianus (Kuntze) Exell. and its major constituent, geraniin. J. Ethnopharmacol. 2016, 187, 17–27.Izui, S.; Sekine, S.; Maeda, K.; Kuboniwa, M.; Takada, A.; Amano, A.; Nagata, H. Antibacterial activity of curcumin against Periodontopathic bacteria. J. Periodontol. 2016, 87, 83–90Andrade, J.T.; Fantini de Figueiredo, G.; Cruz, L.F.; Eliza de Morais, S.; Souza, C.D.F.; Pinto, F.C.H.; Ferreira, J.M.S.; de Freitas Araújo, M.G. Efficacy of curcumin in the treatment of experimental vulvovaginal candidiasis. Rev. Iberoam. Micol. 2019, 36, 192–199.Zhang, X.-L.; Guo, Y.-S.; Wang, C.-H.; Li, G.-Q.; Xu, J.-J.; Chung, H.Y.; Ye, W.-C.; Li, Y.-L.; Wang, G.-C. Phenolic compounds from Origanum vulgare and their antioxidant and antiviral activities. 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