Antiviral role of phenolic compounds against dengue virus: a review
Phenolic compounds have been related to multiple biological activities, and the antiviral effect of these compounds has been demonstrated in several viral models of public health concern. In this review, we show the antiviral role of phenolic compounds against dengue virus (DENV), the most widesprea...
- Autores:
-
Loaiza Cano, Vanessa
Monsalve Escudero, Laura Milena
Martínez Gutierrez, Marlen
de Souza, Damião Pergentin
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2021
- Institución:
- Universidad Cooperativa de Colombia
- Repositorio:
- Repositorio UCC
- Idioma:
- OAI Identifier:
- oai:repository.ucc.edu.co:20.500.12494/32927
- Acceso en línea:
- https://hdl.handle.net/20.500.12494/32927
- Palabra clave:
- Natural products
Flavonoids
Tannins
Phenol
Medicinal plants
Mosquitoes
Dengue virus
Viruses
- Rights
- openAccess
- License
- Atribución – No comercial – Compartir igual
| Summary: | Phenolic compounds have been related to multiple biological activities, and the antiviral effect of these compounds has been demonstrated in several viral models of public health concern. In this review, we show the antiviral role of phenolic compounds against dengue virus (DENV), the most widespread arbovirus globally that, after its re-emergence, has caused multiple epidemic outbreaks, especially in the last two years. Twenty phenolic compounds with anti-DENV activity are discussed, including the multiple mechanisms of action, such as those directed against viral particles or viral proteins, host proteins or pathways related to the productive replication viral cycle and the spread of the infection. |
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