Teratogenic effects of organophosphate insecticides in the etiology of cleft lip palate: literature review
Objective: Evaluate the scientific evidence about the associated relation between the individuals exposure to organophosphates insecticides with the prevalence of non syndromic cleft lip and palate. Material and Methods: The search of scientific articles was held in the data base of PubMed, Science...
- Autores:
-
Ortega-Miller, Jesús Gabriel
Yezioro-Rubinsky, Salomón
Benavides-Pinto, Berta Cecilia
Báez-Quintero, Liliana Carolina
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2017
- Institución:
- Universidad Cooperativa de Colombia
- Repositorio:
- Repositorio UCC
- Idioma:
- spa
- OAI Identifier:
- oai:repository.ucc.edu.co:20.500.12494/9728
- Acceso en línea:
- https://revistas.ucc.edu.co/index.php/od/article/view/1658
https://hdl.handle.net/20.500.12494/9728
- Palabra clave:
- Rights
- openAccess
- License
- Derechos de autor 2017 Revista Nacional de Odontología
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| dc.title.eng.fl_str_mv |
Teratogenic effects of organophosphate insecticides in the etiology of cleft lip palate: literature review |
| dc.title.spa.fl_str_mv |
Efectos teratogénicos de insecticidas organofosforados en la etiología de labio y paladar hendido: revisión de literatura |
| dc.title.por.fl_str_mv |
Efeitos teratogênicos de inseticidas organofosforados na etiologia de lábio e palato fendidos: revisão de literatura |
| title |
Teratogenic effects of organophosphate insecticides in the etiology of cleft lip palate: literature review |
| spellingShingle |
Teratogenic effects of organophosphate insecticides in the etiology of cleft lip palate: literature review |
| title_short |
Teratogenic effects of organophosphate insecticides in the etiology of cleft lip palate: literature review |
| title_full |
Teratogenic effects of organophosphate insecticides in the etiology of cleft lip palate: literature review |
| title_fullStr |
Teratogenic effects of organophosphate insecticides in the etiology of cleft lip palate: literature review |
| title_full_unstemmed |
Teratogenic effects of organophosphate insecticides in the etiology of cleft lip palate: literature review |
| title_sort |
Teratogenic effects of organophosphate insecticides in the etiology of cleft lip palate: literature review |
| dc.creator.fl_str_mv |
Ortega-Miller, Jesús Gabriel Yezioro-Rubinsky, Salomón Benavides-Pinto, Berta Cecilia Báez-Quintero, Liliana Carolina |
| dc.contributor.author.none.fl_str_mv |
Ortega-Miller, Jesús Gabriel Yezioro-Rubinsky, Salomón Benavides-Pinto, Berta Cecilia Báez-Quintero, Liliana Carolina |
| description |
Objective: Evaluate the scientific evidence about the associated relation between the individuals exposure to organophosphates insecticides with the prevalence of non syndromic cleft lip and palate. Material and Methods: The search of scientific articles was held in the data base of PubMed, Science Direct, Academic Google, Medline, Cochrane and Scielo, published between year 2.000 and 2015, and a series of interviews were held to professionals with a Doctor or Master degree In Toxicology, Public Health, Genetics and Biochemistry that were knowledge about this subject. 25 articles of insecticides were reviewed and 5 semi structural interviews. Results: A statistical number of studies stablish an association between the exposure to pesticides with teratogenic effects related with the cleft lip and palate; in vivo experimental studies in animals correlate the exposure the organophosphates insecticide Clorpilifos, with the higher prevalence of cleft palate. Conclusion: some studies found associated relation between the exposure to organophosphates insecticides with increased the incidence of birth abnormalities. |
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2017 |
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2019-05-14T21:13:03Z |
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2019-05-14T21:13:03Z |
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2017-02-06 |
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Artículo |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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https://revistas.ucc.edu.co/index.php/od/article/view/1658 10.16925/od.v12i24.1658 |
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https://hdl.handle.net/20.500.12494/9728 |
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https://revistas.ucc.edu.co/index.php/od/article/view/1658 https://hdl.handle.net/20.500.12494/9728 |
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10.16925/od.v12i24.1658 |
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spa |
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https://revistas.ucc.edu.co/index.php/od/article/view/1658/2020 |
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Derechos de autor 2017 Revista Nacional de Odontología http://creativecommons.org/licenses/by-nc-nd/4.0 |
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info:eu-repo/semantics/openAccess |
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application/pdf |
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Universidad Cooperativa de Colombia |
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Revista Nacional de Odontología; Vol 13 No 24 (2017) |
| dc.source.spa.fl_str_mv |
Revista Nacional de Odontología; Vol. 13 Núm. 24 (2017) |
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Revista Nacional de Odontología; v. 13 n. 24 (2017) |
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2357-4607 1900-3080 |
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Universidad Cooperativa de Colombia |
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Repositorio Institucional Universidad Cooperativa de Colombia |
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Ortega-Miller, Jesús GabrielYezioro-Rubinsky, SalomónBenavides-Pinto, Berta CeciliaBáez-Quintero, Liliana Carolina2017-02-062019-05-14T21:13:03Z2019-05-14T21:13:03Zhttps://revistas.ucc.edu.co/index.php/od/article/view/165810.16925/od.v12i24.1658https://hdl.handle.net/20.500.12494/9728Objective: Evaluate the scientific evidence about the associated relation between the individuals exposure to organophosphates insecticides with the prevalence of non syndromic cleft lip and palate. Material and Methods: The search of scientific articles was held in the data base of PubMed, Science Direct, Academic Google, Medline, Cochrane and Scielo, published between year 2.000 and 2015, and a series of interviews were held to professionals with a Doctor or Master degree In Toxicology, Public Health, Genetics and Biochemistry that were knowledge about this subject. 25 articles of insecticides were reviewed and 5 semi structural interviews. Results: A statistical number of studies stablish an association between the exposure to pesticides with teratogenic effects related with the cleft lip and palate; in vivo experimental studies in animals correlate the exposure the organophosphates insecticide Clorpilifos, with the higher prevalence of cleft palate. Conclusion: some studies found associated relation between the exposure to organophosphates insecticides with increased the incidence of birth abnormalities.Introducción:el objetivo fue revisar la evidencia científica sobre la asociación entre la exposición de individuos a insecticidas organofosforados, con la prevalencia de labio y paladar fisurado no sindrómico. Materiales y Métodos: se realizaron búsquedas de artículos científicos en las bases de datos Pubmed, Science Direct, Google Académico, Medline, Cochrane y Scielo, publicados entre los años 2000 a 2015. Se buscaron artículos teniendo en cuenta los términos MESH, incluyendo estudios de revisión de literatura, metanalisis, casos y controles, y experimentales in vivo, excluyéndose estudios experimentales in vitro, encontrándose 25 artículos que cumplieron con los criterios de inclusión. Resultados: un significativo número de estudios establecieron una asociación entre la exposición a insecticidas órganofosforados con efectos teratogénicos relacionados con la formación del labio y paladar hendido; estudios experimentales in vivo en animales relacionaron la exposición al Insecticida Organofosforado Clorpirifos, con mayor prevalencia de paladar hendido.Conclusión:Los resultados de la presente revisión de literatura no encontró asociación entre la exposición a Insecticidas Organofosforados y efectos teratogénicos relacionados con la formación del labio y paladar hendido.Introdução: o objetivo foi revisar a evidência científica sobre a associação entrea exposição de indivíduos a inseticidas organofosforados, com a prevalência de lábio e palato fissurados não sindrômicos. Métodos: foram realizadas pesquisas de artigos científicos nas bases de dados Pubmed, Science Direct, Google Acadêmico, Medline, Cochrane e Scielo, publicados entre 2000 e 2015. Buscaram-se artigos levando em consideração os termos mesh, incluindo estudos de revisão de literatura, meta-análise, casos e controles, e experimentais in vivo, excluindo estudos experimentais in vitro. Foram encontrados 25 artigos que cumpriram com os critérios de inclusão. Resultados: um número significativo de estudos estabeleceu uma associação entre a exposição a inseticidas organofosforados com efeitos teratogênicos relacionados com a formação do lábio e palato fendidos; estudos experimentais in vivo em animais relacionaram a exposição ao inseticida organofosforado clorpirifós com maior prevalência de palato fendido. Conclusões: os resultados da presente revisão de literatura não estabelecem associação entre a exposição a inseticidas organofosforados e efeitos teratogênicos relacionados com a formação de lábio e palato fendidos.application/pdfspaUniversidad Cooperativa de Colombiahttps://revistas.ucc.edu.co/index.php/od/article/view/1658/2020Derechos de autor 2017 Revista Nacional de Odontologíahttp://creativecommons.org/licenses/by-nc-nd/4.0info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Revista Nacional de Odontología; Vol 13 No 24 (2017)Revista Nacional de Odontología; Vol. 13 Núm. 24 (2017)Revista Nacional de Odontología; v. 13 n. 24 (2017)2357-46071900-3080Teratogenic effects of organophosphate insecticides in the etiology of cleft lip palate: literature reviewEfectos teratogénicos de insecticidas organofosforados en la etiología de labio y paladar hendido: revisión de literaturaEfeitos teratogênicos de inseticidas organofosforados na etiologia de lábio e palato fendidos: revisão de literaturaArtículohttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionPublication20.500.12494/9728oai:repository.ucc.edu.co:20.500.12494/97282024-07-16 13:25:22.321metadata.onlyhttps://repository.ucc.edu.coRepositorio Institucional Universidad Cooperativa de Colombiabdigital@metabiblioteca.com |