In vitro and in silico anti-dengue activity of compounds obtained from Psidium guajava through bioprospecting.

For decades, bioprospecting has proven to be useful for the identification of compounds with pharmacological potential. Considering the great diversity of Colombian plants and the serious worldwide public health problem of dengue-a disease caused by the dengue virus (DENV)-in the present study, we evaluated the anti-DENV effects of 12 ethanolic extracts derived from plants collected in the Colombian Caribbean coast, and 5 fractions and 5 compounds derived from Psidium guajava.

• Autores: Trujillo-Correa AI; Quintero-Gil DC; Diaz-Castillo F; Quiñones W; Robledo SM; Martínez Gutiérrez, Marlén
• Tipo de recurso: Article of journal
• Fecha de publicación: 2023
• Institución: Universidad Cooperativa de Colombia
• Repositorio: Repositorio UCC
• OAI Identifier: oai:repository.ucc.edu.co:20.500.12494/50903
• Acceso en línea: https://doi.org/10.1186/s12906-019-2695-1; https://www.scopus.com/inward/record.uri?eid=2-s2.0-85074696870&doi=10.1186%2fs12906-019-2695-1&partnerID=40&md5=fd414f467a6af8c5fd3d7235a8a05a02; https://hdl.handle.net/20.500.12494/50903
• Palabra clave: ANTIVIRAL; BIOPROSPECTING; CATECHIN; DENGUE VIRUS; GALLIC ACID; PSIDIUM GUAJAVA; QUERCETIN
• Rights: openAccess
• License: http://purl.org/coar/access_right/c_abf2