Títulos de anticuerpos con vacunas recombinantes vectorizadas para la bursitis infecciosa en pollo de engorde

La presente revisión de literatura tuvo como objetivo describir la respuesta inmune humoral y determinar los títulos de anticuerpos específicos con el uso de las vacunas recombinantes contra bursitis infecciosa en pollo de engorde. Esta revisión recopiló información de 60 artículos, libros, y revist...

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Autores:
Diaz Carvajal, Silvia Carolina
Tipo de recurso:
Trabajo de grado de pregrado
Fecha de publicación:
2024
Institución:
Universidad Cooperativa de Colombia
Repositorio:
Repositorio UCC
Idioma:
spa
OAI Identifier:
oai:repository.ucc.edu.co:20.500.12494/56464
Acceso en línea:
https://hdl.handle.net/20.500.12494/56464
Palabra clave:
vacunación
ELISA
Herpesvirus aviar
Proteína VP2
Anticuerpos
Antibodies
Avian herpesvirus
VP2 protein
Rights
openAccess
License
http://creativecommons.org/licenses/by-nd/4.0/
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network_name_str Repositorio UCC
repository_id_str
dc.title.spa.fl_str_mv Títulos de anticuerpos con vacunas recombinantes vectorizadas para la bursitis infecciosa en pollo de engorde
title Títulos de anticuerpos con vacunas recombinantes vectorizadas para la bursitis infecciosa en pollo de engorde
spellingShingle Títulos de anticuerpos con vacunas recombinantes vectorizadas para la bursitis infecciosa en pollo de engorde
vacunación
ELISA
Herpesvirus aviar
Proteína VP2
Anticuerpos
Antibodies
Avian herpesvirus
VP2 protein
title_short Títulos de anticuerpos con vacunas recombinantes vectorizadas para la bursitis infecciosa en pollo de engorde
title_full Títulos de anticuerpos con vacunas recombinantes vectorizadas para la bursitis infecciosa en pollo de engorde
title_fullStr Títulos de anticuerpos con vacunas recombinantes vectorizadas para la bursitis infecciosa en pollo de engorde
title_full_unstemmed Títulos de anticuerpos con vacunas recombinantes vectorizadas para la bursitis infecciosa en pollo de engorde
title_sort Títulos de anticuerpos con vacunas recombinantes vectorizadas para la bursitis infecciosa en pollo de engorde
dc.creator.fl_str_mv Diaz Carvajal, Silvia Carolina
dc.contributor.advisor.none.fl_str_mv Jimenez Leaño, Ángela Patricia
dc.contributor.author.none.fl_str_mv Diaz Carvajal, Silvia Carolina
dc.subject.proposal.spa.fl_str_mv vacunación
ELISA
Herpesvirus aviar
Proteína VP2
Anticuerpos
topic vacunación
ELISA
Herpesvirus aviar
Proteína VP2
Anticuerpos
Antibodies
Avian herpesvirus
VP2 protein
dc.subject.proposal.eng.fl_str_mv Antibodies
Avian herpesvirus
VP2 protein
description La presente revisión de literatura tuvo como objetivo describir la respuesta inmune humoral y determinar los títulos de anticuerpos específicos con el uso de las vacunas recombinantes contra bursitis infecciosa en pollo de engorde. Esta revisión recopiló información de 60 artículos, libros, y revistas científicas bajo los criterios de inclusión y exclusión. Los títulos de anticuerpos se reportaron por medio de las técnicas más utilizada en serología, el ELISA indirecto (Enzyme-Linked ImmunoSorbent Assay) y seroneutralización. Los resultados se organizaron en tablas, y figuras según el tipo de prueba utilizadas con sus respectivos anticuerpos obtenidos en las diferentes semanas muestreadas. De acuerdo con los resultados obtenidos en las pruebas ELISA y de neutralización que utilizaron el vector Herpesvirus (HVT), se evidenció descenso de anticuerpos en los primeros 10 días, con posterior respuesta de anticuerpos específicos solo hasta los 14 días pos vacunación, con fuerte aumento en las siguientes 3 semanas, con una seroconversión notoria; lo contrario fue reportado por varios autores al evidenciar una respuesta de anticuerpos demorada e ineficaz, en las vacunas que emplearon otro tipo de vector. En conclusión, la respuesta inmune adaptativa es efectiva y duradera al emplear vacunas recombinantes vectorizadas, siendo más evidente con el vector HVT al insertar la proteína de la capside vp2, estimulando la producción de anticuerpos específicos frente a las diferentes cepas de campo; de igual manera interpretar las variaciones en los títulos de anticuerpos con los distintos kits ELISA es clave para comprensión del estado sanitario de las aves.
publishDate 2024
dc.date.accessioned.none.fl_str_mv 2024-07-23T13:32:17Z
dc.date.available.none.fl_str_mv 2024-07-23T13:32:17Z
dc.date.issued.none.fl_str_mv 2024-06-05
dc.type.none.fl_str_mv Trabajo de grado - Pregrado
dc.type.coar.none.fl_str_mv http://purl.org/coar/resource_type/c_7a1f
dc.type.content.none.fl_str_mv Text
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dc.identifier.citation.none.fl_str_mv Diaz Carvajal, S. C. (2024). Títulos de anticuerpos con vacunas recombinantes vectorizadas para la bursitis infecciosa en pollo de engorde. [Tesis de pregrado, Universidad Cooperativa de Colombia]. Repositorio Institucional Universidad Cooperativa de Colombia. https://hdl.handle.net/20.500.12494/56464
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12494/56464
identifier_str_mv Diaz Carvajal, S. C. (2024). Títulos de anticuerpos con vacunas recombinantes vectorizadas para la bursitis infecciosa en pollo de engorde. [Tesis de pregrado, Universidad Cooperativa de Colombia]. Repositorio Institucional Universidad Cooperativa de Colombia. https://hdl.handle.net/20.500.12494/56464
url https://hdl.handle.net/20.500.12494/56464
dc.language.iso.none.fl_str_mv spa
language spa
dc.relation.references.none.fl_str_mv Rehman ZU, Meng C, Umar S, Munir M, Ding C. Interaction of infectious bursal disease virus with the immune system of poultry. Vol. 72, World’s Poultry Science Journal. Cambridge University Press; 2016. p. 805–20.
Müller H, Mundt E, Eterradossi N, Islam MR. Current status of vaccines against infectious bursal disease. Avian Pathol. 2012;41(2).
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Boudaoud A, Mamache B, Tombari W, Ghram A. Virus mutations and their impact on vaccination against infectious bursal disease (Gumboro disease). OIE Rev Sci Tech. 2016;35(3).
Jackwood DJ. Advances in vaccine research against economically important viral diseases of food animals: Infectious bursal disease virus. Vet Microbiol. 2017;206.
Dey S, Pathak D, Ramamurthy N, Maity HK, Chellappa MM. Infectious bursal disease virus in chickens: prevalence, impact, and management strategies. Vet Med Res Reports. 2019 Aug;Volume 10:85–97.
Zachar T, Popowich S, Goodhope B, Knezacek T, Ojkic D, Willson P, et al. A 5-year study of the incidence and economic impact of variant infectious bursal disease viruses on broiler production in Saskatchewan, Canada. Can J Vet Res. 2016;80(4).
Cubas-Gaona LL, Courtillon C, Briand FX, Cotta H, Bougeard S, Hirchaud E, et al. High antigenic diversity of serotype 1 infectious bursal disease virus revealed by antigenic cartography. Virus Res. 2023;323.
Gómez Ramírez AP, Beltrán León MY, Álvarez Mira DM, Ramírez Nieto GC. Identificación de genogrupos del virus de la Enfermedad de Gumboro en granjas avícolas en Colombia. Acta Biológica Colomb. 2019;24(3).
Ingrao F, Rauw F, Lambrecht B, Van den Berg T. Infectious Bursal Disease: A complex host-pathogen interaction. Dev Comp Immunol. 2013;41(3).
Dunn JR, Dimitrov KM, Miller PJ, Garcia M, Turner-Alston K, Brown A, et al. Evaluation of Protective Efficacy When Combining Turkey Herpesvirus–Vector Vaccines. Avian Dis. 2019;63(1).
Ge J, An Q, Song S, Gao D, Ping W. Construction of recombinant baculoviruses expressing infectious bursal disease virus main protective antigen and their immune effects on chickens. PLoS One. 2015;10(7).
Andoh K, Yamazaki K, Honda Y, Honda T. Turkey herpesvirus with an insertion in the UL3-4 region displays an appropriate balance between growth activity and antibody-eliciting capacity and is suitable for the establishment of a recombinant vaccine. Arch Virol. 2017;162(4).
Kurukulasuriya S, Ahmed KA, Ojkic D, Gunawardana T, Goonewardene K, Gupta A, et al. Modified live infectious bursal disease virus (IBDV) vaccine delays infection of neonatal broiler chickens with variant IBDV compared to turkey herpesvirus (HVT)-IBDV vectored vaccine. Vaccine. 2017;35(6).
Muniz EC, Verdi R, Jackwood DJ, Kuchpel D, Resende MS, Mattos JCQ, et al. Molecular epidemiologic survey of infectious bursal disease viruses in broiler farms raised under different vaccination programs1. Muniz EC, Verdi R, Jackwood DJ, Kuchpel D, Resende MS, Mattos JCQ, et al. Molecular epidemiologic survey of infectious bursa. J Appl Poult Res. 2018 Jun 1;27(2):253–61.
Zhang S, Zheng S. Host Combats IBDV Infection at Both Protein and RNA Levels. Vol. 14, Viruses. 2022.
Liang J, Yin Y, Qin T, Yang Q. Chicken bone marrow-derived dendritic cells maturation in response to infectious bursal disease virus. Vet Immunol Immunopathol. 2015;164(1–2).
Mosley YYC, Wu CC, Lin TL. Avian viral vector vaccines for infectious bursal disease. Taiwan Vet J. 2015;41(03).
Tang N, Zhang Y, Pedrera M, Chang P, Baigent S, Moffat K, et al. A simple and rapid approach to develop recombinant avian herpesvirus vectored vaccines using CRISPR/Cas9 system. Vaccine. 2018;36(5).
Peebles ED. In ovo applications in poultry: A review. Vol. 97, Poultry Science. 2018.
Journal O, Adino GW, Bayu MD. VETERINARY MEDICINE Article information Review of Diagnostic and Vaccination Approaches of Infectious Bursal Disease of Poultry. Vet Med Open J. 2022;7(1):22–8.
Gallo AMC, Moreno GLX. Evaluación comparativa de dos test de ELISA para la enfermedad de gumboro en aves vacunadas con una vacuna recombinante. Univ Coop Colomb. 2018;
Yepes-Nuñez JJ, Urrútia G, Romero-García M, Alonso-Fernández S. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. Rev Esp Cardiol. 2021;74(9):790–9.
Abdul-Cader MS, Palomino-Tapia V, Amarasinghe A, Ahmed-Hassan H, De Silva Senapathi U, Abdul-Careem MF. Hatchery Vaccination Against Poultry Viral Diseases: Potential Mechanisms and Limitations. Viral Immunol. 2018;31(1):23–33.
Allison Collett Boone. The Effect of In Ovo Vaccination with Herpesvirus of Turkey (HVT) on the Ability to Hasten Immunocompetence in Meat-Type Chickens. [North Carolina]: dissertation submitted to the Graduate Faculty of North Carolina State University; 2023.
Gewaily MS, El-Khyat F, Tahoon AE, Al-Rasheed M, Abdo SE, Gado A, et al. Cytokines, Serological, and Histopathological Assessment of Recombinant Vaccination Strategies for Combatting Infectious Bursal Disease in Broiler Chickens. Vaccines. 2024 Jan 1;12(1).
Ebrahimi MM, Shahsavandi S, Shayan P, Goudarzi H, Masoudi S. Recombinant VP2 expressed in baculovirus and adjuvanted with TIR-TLR7: a vaccine candidate against infectious bursal disease virus. Comp Clin Path. 2018;27(4).
Lemiere S, Perozo F, de Saint-Vis B, Diasparra J, Carlotti A, Morillon P, et al. Hatchery Vaccination Quality Control of Herpesvirus of Turkey-Infectious Bursal Disease HVT-IBD viral vector vaccine application by specific qPCR. Int J Poult Sci. 2012;11(9).
Ingrao F, Rauw F, van den Berg T, Lambrecht B. Characterization of two recombinant HVT-IBD vaccines by VP2 insert detection and cell-mediated immunity after vaccination of specific pathogen-free chickens. Avian Pathol. 2017;46(3).
Richetta M, Gómez E, Lucero MS, Chimeno Zoth S, Gravisaco MJ, Calamante G, et al. Comparison of homologous and heterologous prime-boost immunizations combining MVA-vectored and plant-derived VP2 as a strategy against IBDV. Vaccine. 2017;35(1).
Li K, Liu Y, Liu C, Gao L, Gao Y, Zhang Y, et al. Evaluation of two strains of Marek’s disease virus serotype 1 for the development of recombinant vaccines against very virulent infectious bursal disease virus. Antiviral Res. 2017;139.
Li K, Liu Y, Zhang Y, Gao L, Liu C, Cui H, et al. Protective efficacy of a novel recombinant Marek’s disease virus vector vaccine against infectious bursal disease in chickens with or without maternal antibodies. Vet Immunol Immunopathol. 2017;186.
Ge J, Wang X, Tian M, Wen Z, Feng Q, Qi X, et al. Novel in-ovo chimeric recombinant Newcastle disease vaccine protects against both Newcastle disease and infectious bursal disease. Vaccine. 2014;32(13).
Dey S, Chellappa MM, Pathak DC, Gaikwad S, Yadav K, Ramakrishnan S, et al. Newcastle disease virus vectored bivalent vaccine against virulent infectious bursal disease and Newcastle disease of chickens. Vaccines. 2017;5(4).
Camilotti E, Moraes LB, Furian TQ, Borges KA, Moraes HLS, Salle CTP. Infectious bursal disease: Pathogenicity and immunogenicity of vaccines. Rev Bras Cienc Avic / Brazilian J Poult Sci. 2016;18(2).
Presentado G, Caballero JG, Álvarez FL, Vergara OD, Álvarez R. Niveles de anticuerpos vacunales contra enfermedad de Gumboro en pollitos parrilleros a los 21 y 28 días post-nacimiento. Rev Vet. 2018;29(2).
Sedeik ME, El-Shall NA, Awad AM, Abd El-Hack ME, Alowaimer AN, Swelum AA. Comparative evaluation of HVT-IBD vector, immune complex, and live IBD vaccines against vvIBDV in commercial broiler chickens with high maternally derived antibodies. Animals. 2019;9(3).
Ishihara Y, Esaki M, Saitoh S, Yasuda A. Combination of Two Marek’s Disease Virus Vectors Shows Effective Vaccination Against Marek’s Disease, Infectious Bursal Disease, and Newcastle Disease. Avian Dis. 2016;60(2).
Gao H, Li K, Gao L, Qi X, Gao Y, Qin L, et al. DNA prime-protein boost vaccination enhances protective immunity against infectious bursal disease virus in chickens. Vet Microbiol. 2013;164(1–2).
Lemiere S, Gauthier JC, Kodjo A, Vinit L, Delvecchio A, Prandini F. Evaluation of the Protection against Infectious Bursal Disease (IBD) Challenge in Progeny Born to Parents Having Received a Vaccination Program Using a Herpesvirus of Turkey-Infectious Bursal Disease (HVT-IBD) Vector Vaccine. World J Vaccines. 2013;03(02).
Sultan H, Hussein HA, Abd El-Razik AG, El-Balall S, Talaat SM, Shehata AA. Efficacy of HVT-IBDV vector vaccine against recent Egyptian vvIBDV in commercial broiler chickens. Int J Poult Sci. 2012;11(11).
Fan L, Wu T, Wang Y, Hussain A, Jiang N, Gao L, et al. Novel variants of infectious bursal disease virus can severely damage the bursa of fabricius of immunized chickens. Vet Microbiol. 2020;240.
Pradhan SN, Prince PR, Madhumathi J, Arunkumar C, Roy P, Narayanan RB, et al. DNA vaccination with VP2 gene fragment confers protection against Infectious Bursal Disease Virus in Chickens. Vet Microbiol. 2014;171(1–2).
Fan L, Wang Y, Jiang N, Gao L, Li K, Gao Y, et al. A reassortment vaccine candidate of the novel variant infectious bursal disease virus. Vet Microbiol. 2020;251.
Sadigh Y, Powers C, Spiro S, Pedrera M, Broadbent A, Nair V. Gallid herpesvirus 3 SB-1 strain as a recombinant viral vector for poultry vaccination. npj Vaccines. 2018;3(1).
Okura T, Otomo H, Suzuki S, Ono Y, Taneno A, Oishi E. Efficacy of a novel in ovo-attenuated live vaccine and recombinant vaccine against a very virulent infectious bursal disease virus in chickens. J Vet Med Sci. 2021;83(11).
Pastyria AS, Budzanivska IG, Polischuk VP. Characterization of vaccine and field IBDV strains in Ukraine for proper vaccine selection for disease prevention. Biopolym Cell. 2018;34(1).
Li K, Liu Y, Liu C, Gao L, Zhang Y, Cui H, et al. Recombinant Marek’s disease virus type 1 provides full protection against very virulent Marek’s and infectious bursal disease viruses in chickens. Sci Rep. 2016;6.
van Hulten MCW, Cruz-Coy J, Gergen L, Pouwels H, ten Dam GB, Verstegen I, et al. Efficacy of a turkey herpesvirus double construct vaccine (HVT-ND-IBD) against challenge with different strains of Newcastle disease, infectious bursal disease and Marek’s disease viruses. Avian Pathol. 2021;50(1).
Qiao Q, Song M, Song C, Zhang Y, Wang X, Huang Q, et al. Single-dose vaccination of recombinant chimeric newcastle disease virus (NDV) LaSota vaccine strain expressing infectious bursal disease virus (IBDV) VP2 gene provides full protection against genotype VII NDV and IBDV challenge. Vaccines. 2021;9(12).
Rashid M, Luo H, Akhter J, Islam M, Islam M, Rahman M, et al. Protection Effect of Vaxxitek HVT + IBD Vaccine Against Infectious Bursal Disease in Broiler Chickens. Progress Agric. 2014;24(1–2).
Lemiere S. Q&A on the Paper of Kurukulasuriya et al. (2017) on IBD Vaccine Efficacy Against a Canadian Variant IBDV Strain in Broiler Chickens. J Clin Exp Immunol. 2018;3(1):14–7.
Shah AU, Wang Z, Zheng Y, Guo R, Chen S, Xu M, et al. Construction of a Novel Infectious Clone of Recombinant Herpesvirus of Turkey Fc-126 Expressing VP2 of IBDV. 2022;(Md).
Roh JH, Kang M, Wei B, Yoon RH, Seo HS, Bahng JY, et al. Efficacy of HVT-IBD vector vaccine compared to attenuated live vaccine using in-ovo vaccination against a Korean very virulent IBDV in commercial broiler chickens. Poult Sci. 2016;95(5).
Gelb J, Jackwood DJ, Brannick EM, Ladman BS. Efficacy of Recombinant HVT-IBD Vaccines Administered to Broiler Chicks from a Single Breeder Flock at 30 and 60 Weeks of Age. Avian Dis. 2016;60(3).
Dobner M, Auerbach M, Mundt E, Preisinger R, Icken W, Rautenschlein S. Immune responses upon in ovo HVT-IBD vaccination vary between different chicken lines. Dev Comp Immunol. 2019;100.
Shrestha A, Sadeyen JR, Iqbal M. Enhancing protective efficacy of poultry vaccines through targeted delivery of antigens to antigen-presenting cells. Vol. 6, Vaccines. 2018.
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spelling Jimenez Leaño, Ángela PatriciaDiaz Carvajal, Silvia Carolina2024-07-23T13:32:17Z2024-07-23T13:32:17Z2024-06-05Diaz Carvajal, S. C. (2024). Títulos de anticuerpos con vacunas recombinantes vectorizadas para la bursitis infecciosa en pollo de engorde. [Tesis de pregrado, Universidad Cooperativa de Colombia]. Repositorio Institucional Universidad Cooperativa de Colombia. https://hdl.handle.net/20.500.12494/56464https://hdl.handle.net/20.500.12494/56464La presente revisión de literatura tuvo como objetivo describir la respuesta inmune humoral y determinar los títulos de anticuerpos específicos con el uso de las vacunas recombinantes contra bursitis infecciosa en pollo de engorde. Esta revisión recopiló información de 60 artículos, libros, y revistas científicas bajo los criterios de inclusión y exclusión. Los títulos de anticuerpos se reportaron por medio de las técnicas más utilizada en serología, el ELISA indirecto (Enzyme-Linked ImmunoSorbent Assay) y seroneutralización. Los resultados se organizaron en tablas, y figuras según el tipo de prueba utilizadas con sus respectivos anticuerpos obtenidos en las diferentes semanas muestreadas. De acuerdo con los resultados obtenidos en las pruebas ELISA y de neutralización que utilizaron el vector Herpesvirus (HVT), se evidenció descenso de anticuerpos en los primeros 10 días, con posterior respuesta de anticuerpos específicos solo hasta los 14 días pos vacunación, con fuerte aumento en las siguientes 3 semanas, con una seroconversión notoria; lo contrario fue reportado por varios autores al evidenciar una respuesta de anticuerpos demorada e ineficaz, en las vacunas que emplearon otro tipo de vector. En conclusión, la respuesta inmune adaptativa es efectiva y duradera al emplear vacunas recombinantes vectorizadas, siendo más evidente con el vector HVT al insertar la proteína de la capside vp2, estimulando la producción de anticuerpos específicos frente a las diferentes cepas de campo; de igual manera interpretar las variaciones en los títulos de anticuerpos con los distintos kits ELISA es clave para comprensión del estado sanitario de las aves.The objective of this literature review was to describe the humoral immune response and to determine the specific antibody titers with the use of recombinant vaccines against infectious bursitis in broilers. This review collected information from 60 articles, books, and scientific journals under inclusion and exclusion criteria. Antibody titers were reported by means of the most commonly used technique in serology, the indirect ELISA (Enzyme-Linked ImmunoSorbent Assay), and serum neutralization. The results were organized in tables and figures according to the type of test used with their respective antibodies obtained in the different weeks sampled. According to the results obtained in the Elisa and neutralization tests that used the HVT vector, there was a decrease of antibodies in the first 10 days, with a subsequent response of specific antibodies only up to 14 days post vaccination, with a strong increase in the following 3 weeks, with a notorious seroconversion; the opposite was reported by several authors when using the vector serotype 1 of marek's virus. In conclusion, the adaptive immune response is effective and long lasting when using recombinant vectored vaccines, being more evident with the HVT vector when inserting the vp2 capside protein, stimulating the production of specific antibodies against the different field strains; in the same way, interpreting the variations in antibody titers the different ELISA kits is key to understand the health status of the birds. Key words: vaccination, ELISA, avian herpesvirus, VP2.1. Lista de tablas. -- 2. Lista de figuras. -- 3. Resumen. -- 4. Abstract. -- 5. Introducción. -- 6. Planteamiento de problema. -- 7. Justificación. -- 8. Objetivos. -- 8.1. Objetivo General. -- 9. Marco conceptual. -- 9.1 Patogenia. -- 9.2 Respuesta Inmune humoral. -- 9.3. Anticuerpos específicos con vacunas recombinantes. -- 10. Metodología. -- 10.1. Estrategia de búsqueda. -- 11. Resultados. -- 12. Discusión. -- 13. Conclusiones. -- 14. Recomendación. -- 15. Referencias. -- 16. Agradecimiento.PregradoMedico veterinario y zootecnista59 p.application/pdfspaUniversidad Cooperativa de Colombia, Facultad de Ciencias de la Salud, Medicina Veterinaría y Zootecnia, BucaramangaMedicina veterinaria y zootecniaCiencias de la SaludBucaramangaBucaramangahttp://creativecommons.org/licenses/by-nd/4.0/info:eu-repo/semantics/openAccessAttribution-NoDerivatives 4.0 Internationalhttp://purl.org/coar/access_right/c_abf2Títulos de anticuerpos con vacunas recombinantes vectorizadas para la bursitis infecciosa en pollo de engordeTrabajo de grado - Pregradohttp://purl.org/coar/resource_type/c_7a1fTextinfo:eu-repo/semantics/bachelorThesishttp://purl.org/redcol/resource_type/TPinfo:eu-repo/semantics/acceptedVersionRehman ZU, Meng C, Umar S, Munir M, Ding C. Interaction of infectious bursal disease virus with the immune system of poultry. Vol. 72, World’s Poultry Science Journal. Cambridge University Press; 2016. p. 805–20.Müller H, Mundt E, Eterradossi N, Islam MR. 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