Inflamação e resposta imune inata: Participação das lipoproteínas de altadensidade] [Inflamación y respuesta inmune innata: Participación de las lipoproteínas de alta densidad
The main function of high-density lipoproteins (HDL) is to transport the excess of cholesterol from tissues to the liver, where it is excreted, thus decreasing the risk of atherosclerotic plaques development and cardiovascular diseases establishment. Besides, HDL participates in different processes...
- Autores:
-
Marin Palma, Leidy damariz
Taborda, N. A.
Urcuqui Inchima, S.
Hernández López, Juan Carlos
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2023
- Institución:
- Universidad Cooperativa de Colombia
- Repositorio:
- Repositorio UCC
- Idioma:
- OAI Identifier:
- oai:repository.ucc.edu.co:20.500.12494/49622
- Acceso en línea:
- https://doi.org/10.17533/udea.iatreia.v30n4a06
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85030705478&doi=10.17533%2fudea.iatreia.v30n4a06&partnerID=40&md5=da0620db7ecbbdc7e43430be0acc72fd
https://hdl.handle.net/20.500.12494/49622
- Palabra clave:
- CHOLESTEROL
HDL
IMMUNE RESPONSE
IMMUNOMODULATION
- Rights
- openAccess
- License
- http://purl.org/coar/access_right/c_abf2
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Marin Palma, Leidy damarizTaborda, N. A.Urcuqui Inchima, S.Hernández López, Juan Carlos 2023-05-24T16:21:34Z2023-05-24T16:21:34Z01/10/2017https://doi.org/10.17533/udea.iatreia.v30n4a06https://www.scopus.com/inward/record.uri?eid=2-s2.0-85030705478&doi=10.17533%2fudea.iatreia.v30n4a06&partnerID=40&md5=da0620db7ecbbdc7e43430be0acc72fd01210793https://hdl.handle.net/20.500.12494/49622Marin Palma Leidy damariz,Taborda N.A.,Urcuqui-Inchima S.,Hernandez Lopez Juan carlos.Inflamação e resposta imune inata: Participação das lipoproteínas de altadensidade] [Inflamación y respuesta inmune innata: Participación de las lipoproteínas de alta densidad.Iatreia. 2017. 30. (4):p. 423-435The main function of high-density lipoproteins (HDL) is to transport the excess of cholesterol from tissues to the liver, where it is excreted, thus decreasing the risk of atherosclerotic plaques development and cardiovascular diseases establishment. Besides, HDL participates in different processes of the immune response, as its components have anti-inflammatory, anti-oxidative and anti-apoptotic activities, among others. At cellular level, these lipoproteins have the ability to modify lipid rafts, critical micro-domains that participate in signaling pathways in response to pathogens. Likewise, it has been reported that HDL have a great impact in sepsis, as they eliminate the excess of LPS in blood and transport it to the liver for its elimination, and downregulate the expression of TLR4, main receptor of this molecule. Also, HDL can modulate humoral innate immune responses through regulating the activation of the complement pathway and the expression of pentraxin 3, resulting in the modulation of inflammatory processes. In fact, it has been reported that in several infectious diseases, atherosclerosis and sepsis, the level and function of HDL are altered, which associates with the progress of the diseases. © 2017, Universidad de Antioquia. All rights reserved.0000-0002-9200-5698juanc.hernandezl@campusucc.edu.co423-435Universidad de AntioquiaCHOLESTEROLHDLIMMUNE RESPONSEIMMUNOMODULATIONInflamação e resposta imune inata: Participação das lipoproteínas de altadensidade] [Inflamación y respuesta inmune innata: Participación de las lipoproteínas de alta densidadArtículohttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionIatreiainfo:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Publication20.500.12494/49622oai:repository.ucc.edu.co:20.500.12494/496222024-08-20 16:22:39.706metadata.onlyhttps://repository.ucc.edu.coRepositorio Institucional Universidad Cooperativa de Colombiabdigital@metabiblioteca.com |
dc.title.spa.fl_str_mv |
Inflamação e resposta imune inata: Participação das lipoproteínas de altadensidade] [Inflamación y respuesta inmune innata: Participación de las lipoproteínas de alta densidad |
title |
Inflamação e resposta imune inata: Participação das lipoproteínas de altadensidade] [Inflamación y respuesta inmune innata: Participación de las lipoproteínas de alta densidad |
spellingShingle |
Inflamação e resposta imune inata: Participação das lipoproteínas de altadensidade] [Inflamación y respuesta inmune innata: Participación de las lipoproteínas de alta densidad CHOLESTEROL HDL IMMUNE RESPONSE IMMUNOMODULATION |
title_short |
Inflamação e resposta imune inata: Participação das lipoproteínas de altadensidade] [Inflamación y respuesta inmune innata: Participación de las lipoproteínas de alta densidad |
title_full |
Inflamação e resposta imune inata: Participação das lipoproteínas de altadensidade] [Inflamación y respuesta inmune innata: Participación de las lipoproteínas de alta densidad |
title_fullStr |
Inflamação e resposta imune inata: Participação das lipoproteínas de altadensidade] [Inflamación y respuesta inmune innata: Participación de las lipoproteínas de alta densidad |
title_full_unstemmed |
Inflamação e resposta imune inata: Participação das lipoproteínas de altadensidade] [Inflamación y respuesta inmune innata: Participación de las lipoproteínas de alta densidad |
title_sort |
Inflamação e resposta imune inata: Participação das lipoproteínas de altadensidade] [Inflamación y respuesta inmune innata: Participación de las lipoproteínas de alta densidad |
dc.creator.fl_str_mv |
Marin Palma, Leidy damariz Taborda, N. A. Urcuqui Inchima, S. Hernández López, Juan Carlos |
dc.contributor.author.none.fl_str_mv |
Marin Palma, Leidy damariz Taborda, N. A. Urcuqui Inchima, S. Hernández López, Juan Carlos |
dc.subject.spa.fl_str_mv |
CHOLESTEROL HDL IMMUNE RESPONSE IMMUNOMODULATION |
topic |
CHOLESTEROL HDL IMMUNE RESPONSE IMMUNOMODULATION |
description |
The main function of high-density lipoproteins (HDL) is to transport the excess of cholesterol from tissues to the liver, where it is excreted, thus decreasing the risk of atherosclerotic plaques development and cardiovascular diseases establishment. Besides, HDL participates in different processes of the immune response, as its components have anti-inflammatory, anti-oxidative and anti-apoptotic activities, among others. At cellular level, these lipoproteins have the ability to modify lipid rafts, critical micro-domains that participate in signaling pathways in response to pathogens. Likewise, it has been reported that HDL have a great impact in sepsis, as they eliminate the excess of LPS in blood and transport it to the liver for its elimination, and downregulate the expression of TLR4, main receptor of this molecule. Also, HDL can modulate humoral innate immune responses through regulating the activation of the complement pathway and the expression of pentraxin 3, resulting in the modulation of inflammatory processes. In fact, it has been reported that in several infectious diseases, atherosclerosis and sepsis, the level and function of HDL are altered, which associates with the progress of the diseases. © 2017, Universidad de Antioquia. All rights reserved. |
publishDate |
2023 |
dc.date.issued.none.fl_str_mv |
01/10/2017 |
dc.date.accessioned.none.fl_str_mv |
2023-05-24T16:21:34Z |
dc.date.available.none.fl_str_mv |
2023-05-24T16:21:34Z |
dc.type.none.fl_str_mv |
Artículo |
dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
dc.type.coar.none.fl_str_mv |
http://purl.org/coar/resource_type/c_6501 |
dc.type.coarversion.none.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
dc.type.driver.none.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.redcol.none.fl_str_mv |
http://purl.org/redcol/resource_type/ART |
dc.type.version.none.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
http://purl.org/coar/resource_type/c_6501 |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
https://doi.org/10.17533/udea.iatreia.v30n4a06 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85030705478&doi=10.17533%2fudea.iatreia.v30n4a06&partnerID=40&md5=da0620db7ecbbdc7e43430be0acc72fd |
dc.identifier.issn.spa.fl_str_mv |
01210793 |
dc.identifier.uri.none.fl_str_mv |
https://hdl.handle.net/20.500.12494/49622 |
dc.identifier.bibliographicCitation.spa.fl_str_mv |
Marin Palma Leidy damariz,Taborda N.A.,Urcuqui-Inchima S.,Hernandez Lopez Juan carlos.Inflamação e resposta imune inata: Participação das lipoproteínas de altadensidade] [Inflamación y respuesta inmune innata: Participación de las lipoproteínas de alta densidad.Iatreia. 2017. 30. (4):p. 423-435 |
url |
https://doi.org/10.17533/udea.iatreia.v30n4a06 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85030705478&doi=10.17533%2fudea.iatreia.v30n4a06&partnerID=40&md5=da0620db7ecbbdc7e43430be0acc72fd https://hdl.handle.net/20.500.12494/49622 |
identifier_str_mv |
01210793 Marin Palma Leidy damariz,Taborda N.A.,Urcuqui-Inchima S.,Hernandez Lopez Juan carlos.Inflamação e resposta imune inata: Participação das lipoproteínas de altadensidade] [Inflamación y respuesta inmune innata: Participación de las lipoproteínas de alta densidad.Iatreia. 2017. 30. (4):p. 423-435 |
dc.relation.ispartofjournal.spa.fl_str_mv |
Iatreia |
dc.rights.accessrights.none.fl_str_mv |
info:eu-repo/semantics/openAccess |
dc.rights.coar.none.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
http://purl.org/coar/access_right/c_abf2 |
dc.format.extent.spa.fl_str_mv |
423-435 |
dc.publisher.spa.fl_str_mv |
Universidad de Antioquia |
institution |
Universidad Cooperativa de Colombia |
repository.name.fl_str_mv |
Repositorio Institucional Universidad Cooperativa de Colombia |
repository.mail.fl_str_mv |
bdigital@metabiblioteca.com |
_version_ |
1814247275257397248 |