Inflamação e resposta imune inata: Partici­pação das lipoproteínas de altadensidade] [Inflamación y respuesta inmune innata: Participación de las lipoproteínas de alta densidad

The main function of high-density lipoproteins (HDL) is to transport the excess of cholesterol from tissues to the liver, where it is excreted, thus decreasing the risk of atherosclerotic plaques development and cardiovascular diseases establishment. Besides, HDL participates in different processes...

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Autores:
Marin Palma, Leidy damariz
Taborda, N. A.
Urcuqui Inchima, S.
Hernández López, Juan Carlos
Tipo de recurso:
Article of journal
Fecha de publicación:
2023
Institución:
Universidad Cooperativa de Colombia
Repositorio:
Repositorio UCC
Idioma:
OAI Identifier:
oai:repository.ucc.edu.co:20.500.12494/49622
Acceso en línea:
https://doi.org/10.17533/udea.iatreia.v30n4a06
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85030705478&doi=10.17533%2fudea.iatreia.v30n4a06&partnerID=40&md5=da0620db7ecbbdc7e43430be0acc72fd
https://hdl.handle.net/20.500.12494/49622
Palabra clave:
CHOLESTEROL
HDL
IMMUNE RES­PONSE
IMMUNOMODULATION
Rights
openAccess
License
http://purl.org/coar/access_right/c_abf2
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repository_id_str
spelling Marin Palma, Leidy damarizTaborda, N. A.Urcuqui Inchima, S.Hernández López, Juan Carlos 2023-05-24T16:21:34Z2023-05-24T16:21:34Z01/10/2017https://doi.org/10.17533/udea.iatreia.v30n4a06https://www.scopus.com/inward/record.uri?eid=2-s2.0-85030705478&doi=10.17533%2fudea.iatreia.v30n4a06&partnerID=40&md5=da0620db7ecbbdc7e43430be0acc72fd01210793https://hdl.handle.net/20.500.12494/49622Marin Palma Leidy damariz,Taborda N.A.,Urcuqui-Inchima S.,Hernandez Lopez Juan carlos.Inflamação e resposta imune inata: Partici­pação das lipoproteínas de altadensidade] [Inflamación y respuesta inmune innata: Participación de las lipoproteínas de alta densidad.Iatreia. 2017. 30. (4):p. 423-435The main function of high-density lipoproteins (HDL) is to transport the excess of cholesterol from tissues to the liver, where it is excreted, thus decreasing the risk of atherosclerotic plaques development and cardiovascular diseases establishment. Besides, HDL participates in different processes of the immune response, as its components have anti-inflammatory, anti-oxidative and anti-apoptotic activities, among others. At cellular level, these lipoproteins have the ability to modify lipid rafts, critical micro-domains that participate in signaling pathways in response to pathogens. Likewise, it has been reported that HDL have a great impact in sepsis, as they eliminate the excess of LPS in blood and transport it to the liver for its elimination, and downregulate the expression of TLR4, main receptor of this molecule. Also, HDL can modulate humoral innate immune responses through regulating the activation of the complement pathway and the expression of pentraxin 3, resulting in the modulation of inflammatory processes. In fact, it has been reported that in several infectious diseases, atherosclerosis and sepsis, the level and function of HDL are altered, which associates with the progress of the diseases. © 2017, Universidad de Antioquia. All rights reserved.0000-0002-9200-5698juanc.hernandezl@campusucc.edu.co423-435Universidad de AntioquiaCHOLESTEROLHDLIMMUNE RES­PONSEIMMUNOMODULATIONInflamação e resposta imune inata: Partici­pação das lipoproteínas de altadensidade] [Inflamación y respuesta inmune innata: Participación de las lipoproteínas de alta densidadArtículohttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionIatreiainfo:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Publication20.500.12494/49622oai:repository.ucc.edu.co:20.500.12494/496222024-08-20 16:22:39.706metadata.onlyhttps://repository.ucc.edu.coRepositorio Institucional Universidad Cooperativa de Colombiabdigital@metabiblioteca.com
dc.title.spa.fl_str_mv Inflamação e resposta imune inata: Partici­pação das lipoproteínas de altadensidade] [Inflamación y respuesta inmune innata: Participación de las lipoproteínas de alta densidad
title Inflamação e resposta imune inata: Partici­pação das lipoproteínas de altadensidade] [Inflamación y respuesta inmune innata: Participación de las lipoproteínas de alta densidad
spellingShingle Inflamação e resposta imune inata: Partici­pação das lipoproteínas de altadensidade] [Inflamación y respuesta inmune innata: Participación de las lipoproteínas de alta densidad
CHOLESTEROL
HDL
IMMUNE RES­PONSE
IMMUNOMODULATION
title_short Inflamação e resposta imune inata: Partici­pação das lipoproteínas de altadensidade] [Inflamación y respuesta inmune innata: Participación de las lipoproteínas de alta densidad
title_full Inflamação e resposta imune inata: Partici­pação das lipoproteínas de altadensidade] [Inflamación y respuesta inmune innata: Participación de las lipoproteínas de alta densidad
title_fullStr Inflamação e resposta imune inata: Partici­pação das lipoproteínas de altadensidade] [Inflamación y respuesta inmune innata: Participación de las lipoproteínas de alta densidad
title_full_unstemmed Inflamação e resposta imune inata: Partici­pação das lipoproteínas de altadensidade] [Inflamación y respuesta inmune innata: Participación de las lipoproteínas de alta densidad
title_sort Inflamação e resposta imune inata: Partici­pação das lipoproteínas de altadensidade] [Inflamación y respuesta inmune innata: Participación de las lipoproteínas de alta densidad
dc.creator.fl_str_mv Marin Palma, Leidy damariz
Taborda, N. A.
Urcuqui Inchima, S.
Hernández López, Juan Carlos
dc.contributor.author.none.fl_str_mv Marin Palma, Leidy damariz
Taborda, N. A.
Urcuqui Inchima, S.
Hernández López, Juan Carlos
dc.subject.spa.fl_str_mv CHOLESTEROL
HDL
IMMUNE RES­PONSE
IMMUNOMODULATION
topic CHOLESTEROL
HDL
IMMUNE RES­PONSE
IMMUNOMODULATION
description The main function of high-density lipoproteins (HDL) is to transport the excess of cholesterol from tissues to the liver, where it is excreted, thus decreasing the risk of atherosclerotic plaques development and cardiovascular diseases establishment. Besides, HDL participates in different processes of the immune response, as its components have anti-inflammatory, anti-oxidative and anti-apoptotic activities, among others. At cellular level, these lipoproteins have the ability to modify lipid rafts, critical micro-domains that participate in signaling pathways in response to pathogens. Likewise, it has been reported that HDL have a great impact in sepsis, as they eliminate the excess of LPS in blood and transport it to the liver for its elimination, and downregulate the expression of TLR4, main receptor of this molecule. Also, HDL can modulate humoral innate immune responses through regulating the activation of the complement pathway and the expression of pentraxin 3, resulting in the modulation of inflammatory processes. In fact, it has been reported that in several infectious diseases, atherosclerosis and sepsis, the level and function of HDL are altered, which associates with the progress of the diseases. © 2017, Universidad de Antioquia. All rights reserved.
publishDate 2023
dc.date.issued.none.fl_str_mv 01/10/2017
dc.date.accessioned.none.fl_str_mv 2023-05-24T16:21:34Z
dc.date.available.none.fl_str_mv 2023-05-24T16:21:34Z
dc.type.none.fl_str_mv Artículo
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.coar.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.coarversion.none.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.driver.none.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.none.fl_str_mv https://doi.org/10.17533/udea.iatreia.v30n4a06
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85030705478&doi=10.17533%2fudea.iatreia.v30n4a06&partnerID=40&md5=da0620db7ecbbdc7e43430be0acc72fd
dc.identifier.issn.spa.fl_str_mv 01210793
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12494/49622
dc.identifier.bibliographicCitation.spa.fl_str_mv Marin Palma Leidy damariz,Taborda N.A.,Urcuqui-Inchima S.,Hernandez Lopez Juan carlos.Inflamação e resposta imune inata: Partici­pação das lipoproteínas de altadensidade] [Inflamación y respuesta inmune innata: Participación de las lipoproteínas de alta densidad.Iatreia. 2017. 30. (4):p. 423-435
url https://doi.org/10.17533/udea.iatreia.v30n4a06
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85030705478&doi=10.17533%2fudea.iatreia.v30n4a06&partnerID=40&md5=da0620db7ecbbdc7e43430be0acc72fd
https://hdl.handle.net/20.500.12494/49622
identifier_str_mv 01210793
Marin Palma Leidy damariz,Taborda N.A.,Urcuqui-Inchima S.,Hernandez Lopez Juan carlos.Inflamação e resposta imune inata: Partici­pação das lipoproteínas de altadensidade] [Inflamación y respuesta inmune innata: Participación de las lipoproteínas de alta densidad.Iatreia. 2017. 30. (4):p. 423-435
dc.relation.ispartofjournal.spa.fl_str_mv Iatreia
dc.rights.accessrights.none.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.coar.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
rights_invalid_str_mv http://purl.org/coar/access_right/c_abf2
dc.format.extent.spa.fl_str_mv 423-435
dc.publisher.spa.fl_str_mv Universidad de Antioquia
institution Universidad Cooperativa de Colombia
repository.name.fl_str_mv Repositorio Institucional Universidad Cooperativa de Colombia
repository.mail.fl_str_mv bdigital@metabiblioteca.com
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