Stimulation of TLRs, Nod-like receptors and Dectin-1 in neutrophils induces the production of proinflammatory cytokines
We observed that neutrophils express diverse patterns recognition receptors and adaptor molecules. Stimulation of TLR4, TLR5 and TLR7/8 induces the production of IL-1ß and IL-6, and activation of Dectin-1 leads to secretion of high levels of TNF.
- Autores:
-
Martínez Moreno J.A.
Hernández López, Juan Carlos
Urcuqui-Inchima S.
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2014
- Institución:
- Universidad Cooperativa de Colombia
- Repositorio:
- Repositorio UCC
- Idioma:
- OAI Identifier:
- oai:repository.ucc.edu.co:20.500.12494/42677
- Acceso en línea:
- https://www.scopus.com/inward/record.uri?eid=2-s2.0-84897442406&partnerID=40&md5=48fee5191acec37388ab521d6a714b0e
https://hdl.handle.net/20.500.12494/42677
- Palabra clave:
- C-type Lectin Receptors
Neutrophils
NOD-Like Receptors
Pattern Recognition Receptors
Pro-Inflammatory Cytokines
RIG-I-Like Receptors
Toll-Like Receptors
- Rights
- closedAccess
- License
- http://purl.org/coar/access_right/c_14cb
| Summary: | We observed that neutrophils express diverse patterns recognition receptors and adaptor molecules. Stimulation of TLR4, TLR5 and TLR7/8 induces the production of IL-1ß and IL-6, and activation of Dectin-1 leads to secretion of high levels of TNF. |
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