Extended Hildebrand solubility approach applied to some structurally related sulfonamides in ethanol + water mixtures

Extended Hildebrand Solubility Approach (EHSA) was applied to evaluate the solubility of sulfadiazine, sulfamerazine, and sulfamethazine in some ethanol + water mixtures at 298.15 K. Reported experimental equilibrium solubilities and some fusion properties of these drugs were used for the calculatio...

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Autores:
Delgado, Daniel Ricardo
Peña M.Á.
Martínez F.
Tipo de recurso:
Article of journal
Fecha de publicación:
2016
Institución:
Universidad Cooperativa de Colombia
Repositorio:
Repositorio UCC
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OAI Identifier:
oai:repository.ucc.edu.co:20.500.12494/42212
Acceso en línea:
https://doi.org/10.25054/16576799.1925
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84949870876&doi=10.17533%2fudea.iatreia.v29n1a04&partnerID=40&md5=3ade9af3518d879e86ffcf3d541af2ce
https://hdl.handle.net/20.500.12494/42212
Palabra clave:
Binary mixtures
Ethanol
Extended Hildebrand solubility approach
Hildebrand solubility parameter
Sulfonamides
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closedAccess
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http://purl.org/coar/access_right/c_14cb
id COOPER2_b0dce3fa9a3278fdaa4712bd59fba7b0
oai_identifier_str oai:repository.ucc.edu.co:20.500.12494/42212
network_acronym_str COOPER2
network_name_str Repositorio UCC
repository_id_str
spelling Delgado, Daniel RicardoPeña M.Á.Martínez F.2021-12-16T22:16:06Z2021-12-16T22:16:06Z2016https://doi.org/10.25054/16576799.1925https://www.scopus.com/inward/record.uri?eid=2-s2.0-84949870876&doi=10.17533%2fudea.iatreia.v29n1a04&partnerID=40&md5=3ade9af3518d879e86ffcf3d541af2ce01202804https://hdl.handle.net/20.500.12494/42212Delgado DR,Peña MÁ,Martínez F. Extended Hildebrand solubility approach applied to some structurally related sulfonamides in ethanol + water mixtures. Rev. Colomb. Quim. 2016. 45. (1):p. 34-43. .Extended Hildebrand Solubility Approach (EHSA) was applied to evaluate the solubility of sulfadiazine, sulfamerazine, and sulfamethazine in some ethanol + water mixtures at 298.15 K. Reported experimental equilibrium solubilities and some fusion properties of these drugs were used for the calculations. In particular, a good predictive character of EHSA (with mean deviations lower than 3.0%) were found by using regular polynomials in order four correlating the interaction parameter W with the Hildebrand solubility parameter of solvent mixtures without drug. The predictive character of EHSA was the same as that obtained by direct correlation of drug solubilities with the same descriptor of polarity of the cosolvent mixtures. © 2016, Universidad Nacional de Colombia. All rights reserved.0000-0002-4835-9739danielr.delgado@campusucc.edu.co43-34Universidad Nacional de ColombiaBinary mixturesEthanolExtended Hildebrand solubility approachHildebrand solubility parameterSulfonamidesExtended Hildebrand solubility approach applied to some structurally related sulfonamides in ethanol + water mixturesArtículohttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionRevista Colombiana de Quimicainfo:eu-repo/semantics/closedAccesshttp://purl.org/coar/access_right/c_14cbPublication20.500.12494/42212oai:repository.ucc.edu.co:20.500.12494/422122024-08-20 16:18:56.526metadata.onlyhttps://repository.ucc.edu.coRepositorio Institucional Universidad Cooperativa de Colombiabdigital@metabiblioteca.com
dc.title.spa.fl_str_mv Extended Hildebrand solubility approach applied to some structurally related sulfonamides in ethanol + water mixtures
title Extended Hildebrand solubility approach applied to some structurally related sulfonamides in ethanol + water mixtures
spellingShingle Extended Hildebrand solubility approach applied to some structurally related sulfonamides in ethanol + water mixtures
Binary mixtures
Ethanol
Extended Hildebrand solubility approach
Hildebrand solubility parameter
Sulfonamides
title_short Extended Hildebrand solubility approach applied to some structurally related sulfonamides in ethanol + water mixtures
title_full Extended Hildebrand solubility approach applied to some structurally related sulfonamides in ethanol + water mixtures
title_fullStr Extended Hildebrand solubility approach applied to some structurally related sulfonamides in ethanol + water mixtures
title_full_unstemmed Extended Hildebrand solubility approach applied to some structurally related sulfonamides in ethanol + water mixtures
title_sort Extended Hildebrand solubility approach applied to some structurally related sulfonamides in ethanol + water mixtures
dc.creator.fl_str_mv Delgado, Daniel Ricardo
Peña M.Á.
Martínez F.
dc.contributor.author.none.fl_str_mv Delgado, Daniel Ricardo
Peña M.Á.
Martínez F.
dc.subject.spa.fl_str_mv Binary mixtures
Ethanol
Extended Hildebrand solubility approach
Hildebrand solubility parameter
Sulfonamides
topic Binary mixtures
Ethanol
Extended Hildebrand solubility approach
Hildebrand solubility parameter
Sulfonamides
description Extended Hildebrand Solubility Approach (EHSA) was applied to evaluate the solubility of sulfadiazine, sulfamerazine, and sulfamethazine in some ethanol + water mixtures at 298.15 K. Reported experimental equilibrium solubilities and some fusion properties of these drugs were used for the calculations. In particular, a good predictive character of EHSA (with mean deviations lower than 3.0%) were found by using regular polynomials in order four correlating the interaction parameter W with the Hildebrand solubility parameter of solvent mixtures without drug. The predictive character of EHSA was the same as that obtained by direct correlation of drug solubilities with the same descriptor of polarity of the cosolvent mixtures. © 2016, Universidad Nacional de Colombia. All rights reserved.
publishDate 2016
dc.date.issued.none.fl_str_mv 2016
dc.date.accessioned.none.fl_str_mv 2021-12-16T22:16:06Z
dc.date.available.none.fl_str_mv 2021-12-16T22:16:06Z
dc.type.none.fl_str_mv Artículo
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.coar.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.coarversion.none.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.driver.none.fl_str_mv info:eu-repo/semantics/article
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dc.type.version.none.fl_str_mv info:eu-repo/semantics/publishedVersion
format http://purl.org/coar/resource_type/c_6501
status_str publishedVersion
dc.identifier.none.fl_str_mv https://doi.org/10.25054/16576799.1925
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84949870876&doi=10.17533%2fudea.iatreia.v29n1a04&partnerID=40&md5=3ade9af3518d879e86ffcf3d541af2ce
dc.identifier.issn.spa.fl_str_mv 01202804
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12494/42212
dc.identifier.bibliographicCitation.spa.fl_str_mv Delgado DR,Peña MÁ,Martínez F. Extended Hildebrand solubility approach applied to some structurally related sulfonamides in ethanol + water mixtures. Rev. Colomb. Quim. 2016. 45. (1):p. 34-43. .
url https://doi.org/10.25054/16576799.1925
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84949870876&doi=10.17533%2fudea.iatreia.v29n1a04&partnerID=40&md5=3ade9af3518d879e86ffcf3d541af2ce
https://hdl.handle.net/20.500.12494/42212
identifier_str_mv 01202804
Delgado DR,Peña MÁ,Martínez F. Extended Hildebrand solubility approach applied to some structurally related sulfonamides in ethanol + water mixtures. Rev. Colomb. Quim. 2016. 45. (1):p. 34-43. .
dc.relation.ispartofjournal.spa.fl_str_mv Revista Colombiana de Quimica
dc.rights.accessrights.none.fl_str_mv info:eu-repo/semantics/closedAccess
dc.rights.coar.none.fl_str_mv http://purl.org/coar/access_right/c_14cb
eu_rights_str_mv closedAccess
rights_invalid_str_mv http://purl.org/coar/access_right/c_14cb
dc.format.extent.spa.fl_str_mv 43-34
dc.publisher.spa.fl_str_mv Universidad Nacional de Colombia
institution Universidad Cooperativa de Colombia
repository.name.fl_str_mv Repositorio Institucional Universidad Cooperativa de Colombia
repository.mail.fl_str_mv bdigital@metabiblioteca.com
_version_ 1814246912040108032

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