Differential expression of human beta defensins in placenta and detection of allelic variants in the DEFB1 gene from HIV-1 positive mothers.
Low infection rates in neonates born to HIV-1-seropositive mothers highlight the existence of natural defense mechanisms in the maternal-fetal interface. Human beta defensins (HBDs) inhibit HIV-1 replication in vitro and their variants are associated with HIV-1 resistance/susceptibility.
- Autores:
-
Aguilar-Jiménez W
Zapata Builes, Wildeman
Rugeles MT
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2023
- Institución:
- Universidad Cooperativa de Colombia
- Repositorio:
- Repositorio UCC
- Idioma:
- OAI Identifier:
- oai:repository.ucc.edu.co:20.500.12494/50281
- Acceso en línea:
- https://doi.org/10.1590/S0120-41572011000100007
https://hdl.handle.net/20.500.12494/50281
- Palabra clave:
- Rights
- openAccess
- License
- http://purl.org/coar/access_right/c_abf2
| Summary: | Low infection rates in neonates born to HIV-1-seropositive mothers highlight the existence of natural defense mechanisms in the maternal-fetal interface. Human beta defensins (HBDs) inhibit HIV-1 replication in vitro and their variants are associated with HIV-1 resistance/susceptibility. |
|---|