Abnormal position of lymph nodes in a freemartin sheep.

In this freemartin case report the authors present the clinical and morphological findings of a freemartin ewe with an abnormal position of two lymph nodes. Freemartins, infertile females from mixed-sex twin pregnancies, are chimeras, having two cell populations: one of their own (XX DNA) and one fr...

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Autores:
Gonella Diaza, Angela María
Duarte Rodriguez, Luz Zoraya
Dominguez, Sergio
Salazar Sanchez, Pedro Alvaro
Tipo de recurso:
Article of journal
Fecha de publicación:
2012
Institución:
Universidad Cooperativa de Colombia
Repositorio:
Repositorio UCC
Idioma:
OAI Identifier:
oai:repository.ucc.edu.co:20.500.12494/42153
Acceso en línea:
https://doi.org/10.22354/in.v22i4.736
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84960460550&doi=10.1007%2fs10562-016-1699-4&partnerID=40&md5=d54cb93e44a108409e666d717e6717d6
https://hdl.handle.net/20.500.12494/42153
Palabra clave:
chimera
ewe
freemartinism
testes
vulva
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closedAccess
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http://purl.org/coar/access_right/c_14cb
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network_name_str Repositorio UCC
repository_id_str
spelling Gonella Diaza, Angela MaríaDuarte Rodriguez, Luz ZorayaDominguez, SergioSalazar Sanchez, Pedro Alvaro2021-12-16T22:16:03Z2021-12-16T22:16:03Z2012https://doi.org/10.22354/in.v22i4.736https://www.scopus.com/inward/record.uri?eid=2-s2.0-84960460550&doi=10.1007%2fs10562-016-1699-4&partnerID=40&md5=d54cb93e44a108409e666d717e6717d622302034https://hdl.handle.net/20.500.12494/42153Gonella AM,Duarte LZ,Dominguez S,Salazar PA. Abnormal position of lymph nodes in a freemartin sheep. Vet Med (Auckl). 2012. 3. p. 1-6. .In this freemartin case report the authors present the clinical and morphological findings of a freemartin ewe with an abnormal position of two lymph nodes. Freemartins, infertile females from mixed-sex twin pregnancies, are chimeras, having two cell populations: one of their own (XX DNA) and one from their male twin (XY DNA). Freemartins can have varying degrees of phenotypic masculinization, including, in some cases, having active male gonads and exhibiting male behaviors such as heat detection and aggressiveness. During the clinical examination of the freemartin ewe, a morphological abnormality of the vulva, the presence of scrotal sacs, and a lack of mammary tissue development were noted. On inspection of the vaginal channel, an extremely enlarged clitoris, resembling a penis, was found. The clinical evidence suggested freemartinism. After the karyotyping diagnosis confirmation, a necropsy was performed and samples were taken for histology and immunohistochemistry. There were two structures found in the scrotal sacs; however, these were found to be lymph nodes, not testicles, and this was confirmed by CD3 lymph protein coloration. On histological study, the phallic structure showed corpus cavernosum and tunica albuginea. The testicles were found retained inside the abdominal cavity, with the presence of atrophic seminiferous tubules. Although the position of the testicles in freemartins has been reported as highly variable, this is the first time, to the best of the authors' knowledge, that a case has been reported where lymph nodes have been found inside the scrotal sacs. It is possible that these were the inguinal lymph nodes, trapped inside the scrotum during fetal growth and development.luz.duarte@campusucc.edu.co6-1chimeraewefreemartinismtestesvulvaAbnormal position of lymph nodes in a freemartin sheep.Artículohttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionVeterinary Medicine (auckland, N.Z.)info:eu-repo/semantics/closedAccesshttp://purl.org/coar/access_right/c_14cbPublication20.500.12494/42153oai:repository.ucc.edu.co:20.500.12494/421532024-08-20 16:15:55.86metadata.onlyhttps://repository.ucc.edu.coRepositorio Institucional Universidad Cooperativa de Colombiabdigital@metabiblioteca.com
dc.title.spa.fl_str_mv Abnormal position of lymph nodes in a freemartin sheep.
title Abnormal position of lymph nodes in a freemartin sheep.
spellingShingle Abnormal position of lymph nodes in a freemartin sheep.
chimera
ewe
freemartinism
testes
vulva
title_short Abnormal position of lymph nodes in a freemartin sheep.
title_full Abnormal position of lymph nodes in a freemartin sheep.
title_fullStr Abnormal position of lymph nodes in a freemartin sheep.
title_full_unstemmed Abnormal position of lymph nodes in a freemartin sheep.
title_sort Abnormal position of lymph nodes in a freemartin sheep.
dc.creator.fl_str_mv Gonella Diaza, Angela María
Duarte Rodriguez, Luz Zoraya
Dominguez, Sergio
Salazar Sanchez, Pedro Alvaro
dc.contributor.author.none.fl_str_mv Gonella Diaza, Angela María
Duarte Rodriguez, Luz Zoraya
Dominguez, Sergio
Salazar Sanchez, Pedro Alvaro
dc.subject.spa.fl_str_mv chimera
ewe
freemartinism
testes
vulva
topic chimera
ewe
freemartinism
testes
vulva
description In this freemartin case report the authors present the clinical and morphological findings of a freemartin ewe with an abnormal position of two lymph nodes. Freemartins, infertile females from mixed-sex twin pregnancies, are chimeras, having two cell populations: one of their own (XX DNA) and one from their male twin (XY DNA). Freemartins can have varying degrees of phenotypic masculinization, including, in some cases, having active male gonads and exhibiting male behaviors such as heat detection and aggressiveness. During the clinical examination of the freemartin ewe, a morphological abnormality of the vulva, the presence of scrotal sacs, and a lack of mammary tissue development were noted. On inspection of the vaginal channel, an extremely enlarged clitoris, resembling a penis, was found. The clinical evidence suggested freemartinism. After the karyotyping diagnosis confirmation, a necropsy was performed and samples were taken for histology and immunohistochemistry. There were two structures found in the scrotal sacs; however, these were found to be lymph nodes, not testicles, and this was confirmed by CD3 lymph protein coloration. On histological study, the phallic structure showed corpus cavernosum and tunica albuginea. The testicles were found retained inside the abdominal cavity, with the presence of atrophic seminiferous tubules. Although the position of the testicles in freemartins has been reported as highly variable, this is the first time, to the best of the authors' knowledge, that a case has been reported where lymph nodes have been found inside the scrotal sacs. It is possible that these were the inguinal lymph nodes, trapped inside the scrotum during fetal growth and development.
publishDate 2012
dc.date.issued.none.fl_str_mv 2012
dc.date.accessioned.none.fl_str_mv 2021-12-16T22:16:03Z
dc.date.available.none.fl_str_mv 2021-12-16T22:16:03Z
dc.type.none.fl_str_mv Artículo
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dc.identifier.none.fl_str_mv https://doi.org/10.22354/in.v22i4.736
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dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12494/42153
dc.identifier.bibliographicCitation.spa.fl_str_mv Gonella AM,Duarte LZ,Dominguez S,Salazar PA. Abnormal position of lymph nodes in a freemartin sheep. Vet Med (Auckl). 2012. 3. p. 1-6. .
url https://doi.org/10.22354/in.v22i4.736
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84960460550&doi=10.1007%2fs10562-016-1699-4&partnerID=40&md5=d54cb93e44a108409e666d717e6717d6
https://hdl.handle.net/20.500.12494/42153
identifier_str_mv 22302034
Gonella AM,Duarte LZ,Dominguez S,Salazar PA. Abnormal position of lymph nodes in a freemartin sheep. Vet Med (Auckl). 2012. 3. p. 1-6. .
dc.relation.ispartofjournal.spa.fl_str_mv Veterinary Medicine (auckland, N.Z.)
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institution Universidad Cooperativa de Colombia
repository.name.fl_str_mv Repositorio Institucional Universidad Cooperativa de Colombia
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