Variantes genéticas asociadas con niveles de hemoglobina fetal muestran diversos orígenes étnicos en pacientes colombianos con anemia falciforme

etal hemoglobin is an important factor in modulating the severity of sickle cell anemia. Its level in peripheral blood underlies strong genetic determination. Associated loci with increased levels of fetal hemoglobin display population-specific allele

Autores:
Fong Reales, Cristian Javier
Menzel, Stephan
Lizarralde, María Alejandra
Barreto, Guillermo
Tipo de recurso:
Article of journal
Fecha de publicación:
2015
Institución:
Universidad Cooperativa de Colombia
Repositorio:
Repositorio UCC
Idioma:
OAI Identifier:
oai:repository.ucc.edu.co:20.500.12494/41339
Acceso en línea:
https://doi.org/10.7705/biomedica.v35i3.2573
https://hdl.handle.net/20.500.12494/41339
Palabra clave:
Fetal hemoglobin
polymorphism
single nucleotide
anemia
sickle cell
admixture
beta-globin cluster
BCL11A
HBS1L-MYB
Rights
closedAccess
License
http://purl.org/coar/access_right/c_14cb
Description
Summary:etal hemoglobin is an important factor in modulating the severity of sickle cell anemia. Its level in peripheral blood underlies strong genetic determination. Associated loci with increased levels of fetal hemoglobin display population-specific allele