Diferencias de sexo en severidad y factores de riesgo para caries dental y enfermedad periodontal

Introducción: el objetivo de este estudio fue determinar si existen diferencias de sexo en la severidad y factores de riesgo en la aparición de caries dental y enfermedad periodontal. Métodos: realizamos un estudio retrospectivo transversal a través de la revisión de historias clínicas de 621 pacien...

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Autores:
Mafla, Ana Cristina
Patiño, Mauricio Alexander
Tipo de recurso:
http://purl.org/coar/resource_type/c_f744
Fecha de publicación:
2019
Institución:
Universidad Cooperativa de Colombia
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Repositorio UCC
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oai:repository.ucc.edu.co:20.500.12494/16334
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https://hdl.handle.net/20.500.12494/16334
Palabra clave:
caries dental
enfermedad periodontal
caracteres sexuales
factores de riesgo
epidemiología
dental caries
periodontal disease
sexual characteristics
risk factors
epidemiolog
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oai_identifier_str oai:repository.ucc.edu.co:20.500.12494/16334
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network_name_str Repositorio UCC
repository_id_str
dc.title.spa.fl_str_mv Diferencias de sexo en severidad y factores de riesgo para caries dental y enfermedad periodontal
title Diferencias de sexo en severidad y factores de riesgo para caries dental y enfermedad periodontal
spellingShingle Diferencias de sexo en severidad y factores de riesgo para caries dental y enfermedad periodontal
caries dental
enfermedad periodontal
caracteres sexuales
factores de riesgo
epidemiología
dental caries
periodontal disease
sexual characteristics
risk factors
epidemiolog
title_short Diferencias de sexo en severidad y factores de riesgo para caries dental y enfermedad periodontal
title_full Diferencias de sexo en severidad y factores de riesgo para caries dental y enfermedad periodontal
title_fullStr Diferencias de sexo en severidad y factores de riesgo para caries dental y enfermedad periodontal
title_full_unstemmed Diferencias de sexo en severidad y factores de riesgo para caries dental y enfermedad periodontal
title_sort Diferencias de sexo en severidad y factores de riesgo para caries dental y enfermedad periodontal
dc.creator.fl_str_mv Mafla, Ana Cristina
Patiño, Mauricio Alexander
dc.contributor.advisor.none.fl_str_mv Mafla, Ana Cristina
dc.contributor.author.none.fl_str_mv Mafla, Ana Cristina
Patiño, Mauricio Alexander
dc.subject.spa.fl_str_mv caries dental
enfermedad periodontal
caracteres sexuales
factores de riesgo
epidemiología
topic caries dental
enfermedad periodontal
caracteres sexuales
factores de riesgo
epidemiología
dental caries
periodontal disease
sexual characteristics
risk factors
epidemiolog
dc.subject.other.spa.fl_str_mv dental caries
periodontal disease
sexual characteristics
risk factors
epidemiolog
description Introducción: el objetivo de este estudio fue determinar si existen diferencias de sexo en la severidad y factores de riesgo en la aparición de caries dental y enfermedad periodontal. Métodos: realizamos un estudio retrospectivo transversal a través de la revisión de historias clínicas de 621 pacientes de la clínica de la Facultad de Odontología de la Universidad Cooperativa de Colombia en Pasto, Colombia, durante 2008 y 2013. Se obtuvo el índice Copd e Icdas II para determinar la severidad de caries dental y el Índice Cpitn para evaluar enfermedad periodontal. Se realizó un análisis descriptivo y la asociación entre caries dental y enfermedad periodontal y los factores de riesgo se evaluaron mediante modelos lineales generalizados. Resultados: La media de Copd fue levemente mayor en mujeres (20,97±6,01) que en hombres (20,59±5,47) (P=0,191). Existió diferencia con respecto a dientes perdidos en hombres (4,85±4,54) y mujeres (6,12±5,64) (P=0,020). Encontramos que 12,8 % de hombres y 10,2 % de mujeres tenían bolsas periodontales ≥6mm (P=0,136). La presencia de diastemas (OR=2,881; IC al 95 %: 1,479-5,613; P=0,002) y sangrado gingival (OR=40,263; ic al 95 %: 7,851-206,484; P<0,001) se asociaron significativamente con la enfermedad periodontal en hombres y tener apiñamiento (OR=2,059; IC al 95 %: 1,387-3,055; P<0,001) y estar casada (OR=1,859; IC al 95 %: 1,046-3,304; P<0,034) influyó en esta enfermedad en mujeres. Conclusión: el diseño de estudio retrospectivo transversal es limitado, pero ofrece una vía prometedora para futuras exploraciones. Los resultados tienen implicaciones para la promoción de diferencias en sexo en cuidados de salud oral.
publishDate 2019
dc.date.issued.none.fl_str_mv 2019-03-20
dc.date.accessioned.none.fl_str_mv 2020-01-24T15:45:29Z
dc.date.available.none.fl_str_mv 2020-01-24T15:45:29Z
dc.type.none.fl_str_mv Acta de memorias
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dc.identifier.uri.spa.fl_str_mv 10.16925/2357-4607.2019.01.03
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dc.identifier.bibliographicCitation.spa.fl_str_mv Mafla, A. C. y Patiño, M. A. (2019). Diferencias de sexo en severidad y factores de riesgo para caries dental y enfermedad periodontal. Rev Nac Odontol. 2019;15(28):1-19. Recuperado de: https://revistas.ucc.edu.co/index.php/od/article/view/2596/2629
identifier_str_mv 1900-3080
10.16925/2357-4607.2019.01.03
Mafla, A. C. y Patiño, M. A. (2019). Diferencias de sexo en severidad y factores de riesgo para caries dental y enfermedad periodontal. Rev Nac Odontol. 2019;15(28):1-19. Recuperado de: https://revistas.ucc.edu.co/index.php/od/article/view/2596/2629
url https://hdl.handle.net/20.500.12494/16334
dc.relation.isversionof.spa.fl_str_mv https://revistas.ucc.edu.co/index.php/od/article/view/2596/2629
dc.relation.ispartofjournal.spa.fl_str_mv Revista Nacional de Odontología
dc.relation.references.spa.fl_str_mv 1. Legato MJ. Por qué los hombres nunca recuerdan y las mujeres nunca olvidan. Barcelona: Urano; 2006. 268 p.
2. Gur RC, Mozley LH, Mozley PD, Resnick SM, Karp JS, A Alavi, et al. Sex differences in regional cerebral glucose metabolism during a resting state. Science. 1995; 267: 528-53. Recuperado en: https://www.ncbi.nlm.nih.gov/pubmed/7824953.
3. Petersen PE. The world oral health report 2003: continuous improvement of oral health in the 21st century-the approach of the WHO Global Oral Health Programme. Community Dent Oral Epidemiol. 2003; 31(1): 3-23. Recuperado en: https://www.ncbi.nlm.nih.gov/ pubmed/15015736.
4. Skinner J, Johnson G, Phelan C, Blinkhorn A. Dental caries in 14- and 15-year-olds in New South Wales, Australia. BMC Public Health. 2013; 13: 1060. doi: 10.1186/1471-2458-13-1060.
5. Al-Darwish M, El Ansari W, Bener A. Prevalence of dental caries among 12-14 year old children in Qatar. Saudi Dent J. 2014; 26(3): 115-25. doi: 10.1016/j.sdentj.2014.03.006.
6. Silva AE, Menezes AM, Assunção MC, Gonçalves H, Demarco FF, Vargas-Ferreira F, et al. Validation of self-reported information on dental caries in a birth cohort at 18 years of age. PLoS One. 2014; 9(9): 106382. doi: 10.1371/journal.pone.0106382.
7. Žemaitienė M, Grigalauskienė R, Vasiliauskienė I, Saldūnaitė K, Razmienė J, Slabšinskienė E. Prevalence and severity of dental caries among 18-year-old Lithuanian adolescents. Medicina (Kaunas). 2016; 52(1): 54-60. doi: 10.1016/j.medici.2016.01.006.
8. Kutesa A, Kasangaki A, Nkamba M, Muwazi L, Okullo I, Rwenyonyi CM. Prevalence and factors associated with dental caries among children and adults in selected districts in Uganda. Afr Health Sci. 2015; 15(4): 1302-7. doi: 10.4314/ahs.v15i4.33.
9. Edman K, Öhrn K, Nordström B, Holmlund A, Hellberg D. Trends over 30 years in the prevalence and severity of alveolar bone loss and the influence of smoking and socio-economic factors - based on epidemiological surveys in Sweden 1983-2013. Int J Dent Hyg. 2015; 13(4): 283-91. doi: 10.1111/idh.12164.
10. Aimetti M, Perotto S, Castiglione A, Mariani GM, Ferrarotti F, Romano F. Prevalence of periodontitis in an adult population from an urban area in North Italy: findings from a cross-sectional population-based epidemiological survey. J Clin Periodontol. 2015; 42(7): 622-31. doi: 10.1111/jcpe.12420.
11. Torrungruang K, Tamsailom S, Rojanasomsith K, Sutdhibhisal S, Nisapakultorn K, Vanichjakvong O, et al. Risk indicators of periodontal disease in older Thai adults. J Periodontol. 2005; 76(4): 558-65.
12. Balaji SK, Lavu V, Rao S. Chronic periodontitis prevalence and the inflammatory burden in a sample population from South India. Indian J Dent Res. 2018; 29(2): 254-9. doi: 10.4103/ijdr. IJDR_335_17.
13. Idrees M, Hammad M, Faden A, Kujan O. Influence of body mass index on severity of dental caries: cross-sectional study in healthy adults. Ann Saudi Med. 2017; 37(6): 444-8. doi: 10.5144/0256-4947.2017.444.
14. Ramírez-Puerta BS, Viñas-Sarmiento Y, López-Camacho V, Morales-Flórez JL. Línea de base en caries dental, Antioquia (Colombia), 2011. Rev Nac Odontol. 2012; 8(15): 9-20. doi: 10.16925.issn.1900-3080.
15. Wang L, Cheng L, Yuan B, Hong X, Hu T. Association between socio-economic status and dental caries in elderly people in Sichuan Province, China: a cross-sectional study. BMJ Open. 2017; 7(9): 016557. doi: 10.1136/bmjopen-2017-016557.
16. He S, Thomson WM. An oral epidemiological comparison of Chinese and New Zealand adults in 2 key age groups. Community Dent Oral Epidemiol. 2018; 46(2): 154-160. doi: 10.1111/ cdoe.12348.
17. Lorenzo SM, Álvarez R, Andrade E, Piccardo V, Francia A, Massa Fernando, et al. Periodontal conditions and associated factors among adults and the elderly: findings from the first National Oral Health Survey in Uruguay. Cad. Saúde Pública. 2015; 31(11): 2425-36. doi: 10.1590/0102-311X00012115
18. Vlassoff C. Gender differences in determinants and consequences of health and illness. J Health Popul Nutr. 2007; 25(1): 47-61. Recuperado en: https://www.ncbi.nlm.nih.gov/ pubmed/17615903.
19. Vano M, Gennai S, Karapetsa D, Miceli M, Giuca MR, Gabriele M, et al. The influence of educational level and oral hygiene behaviours on DMFT index and CPITN index in an adult Italian population: An epidemiological study. Int J Dent Hyg. 2015; 13(2): 151-7. doi: 10.1111/idh.12098.
20. Álvarez L, Liberman J, Abreu S, Mangarelli C, Correa MB, Demarco FF, et al. Dental caries in Uruguayan adults and elders: Findings from the first Uruguayan National Oral Health Survey. Cad Saude Publica. 2015; 31(8): 1663-72. doi: 10.1590/0102-311X00132214.
21. Ajayi DM, Abiodun-Solanke IM, Gbadebo SO. A 5-year retrospective study of rampant dental caries among adult patients in a Nigerian Teaching Hospital. Indian J Dent Res. 2015; 26(3): 267-70. doi: 10.4103/0970-9290.162885.
22. Rojas-Gutiérrez WJ, Vivares-Builes AM, Agudelo-Suárez AA. Caries dental e higiene bucal en escolares de la zona rural del municipio de Jericó, Antioquia, 2013. Rev Nac Odontol. 2013; 9(17): 27-34. doi: 10.16925/od.v9i17.569.
23. Lukacs JR, Largaespada LL. Explaining sex differences in dental caries prevalence: saliva, hormones, and ‘‘Life-History’’ etiologies. American Journal of Human Biology. 2006; 18(4): 540-55. Recuperado en: https://www.ncbi.nlm.nih.gov/pubmed/16788889.
24. Stock C, Jürges H, Shen J, Bozorgmehr K, Listl S. A comparison of tooth retention and replacement across 15 countries in the over-50s. Community Dent Oral Epidemiol. 2016; 44(3): 223-31. doi: 10.1111/cdoe.12209.
25. Tsai SJ, Lin MS, Chiu WN, Jane SW, Tu LT, Chen MY. Factors associated with having less than 20 natural teeth in rural adults: a cross-sectional study. BMC Oral Health. 2015; 15(1): 158. doi: 10.1186/s12903-015-0147-y.
26. Tiwari T, Scarbro S, Bryant LL, Puma J. Factors associated with tooth loss in older adults in rural Colorado. J Community Health. 2016; 41(3): 476-81. doi: 10.1007/s10900-015-0117-y.
27. Roohafza H, Afghari P, Keshteli AH, Vali A, Shirani M, Adibi P, Afshar H. The relationship between tooth loss and psychological factors. Community Dent Health. 2015; 32(1): 16-9. Recuperado en: https://www.ncbi.nlm.nih.gov/pubmed/26263587.
28. Bansal M, Mittal N, Singh TB. Assessment of the prevalence of periodontal diseases and treatment needs: A hospital-based study. J Indian Soc Periodontol. 2015; 19(2): 211-5. doi: 10.4103/0972-124X.145810.
29. García-Conde G, Espinosa de Santillana A, Martínez F, Huerta-Herrera N, Islas-Márquez AJ, Medina-Solís E. Periodontal treatment needs in adults from Mixteca rural area in Puebla State, Mexico. Rev. Salud Pública. 2010; 12(4): 647-57. Recuperado en: https://www.ncbi.nlm.nih.gov/ pubmed/21340129.
30. Oertelt-Prigione S. The influence of sex and gender on the immune response. Autoimmun Rev. 2012; 11(6-7): 479-85. doi: 10.1016/j.autrev.2011.11.022. Recuperado en: https://www. ncbi.nlm.nih.gov/pubmed/22155201.
31. Whitacre CC, Reingold SC, O’Looney PA. A gender gap in autoimmunity. Science. 1999; 283(5406): 1277-1278. Recuperado en: https://www.ncbi.nlm.nih.gov/pubmed/10084932
32. Kanda N, Tsuchida T, Tamaki K. Testosterone inhibits immunoglobulin production by human peripheral blood mononuclear cells. Clin Exp Immunol. 1996; 106(2): 410-5. doi: 10.1046/ j.1365-2249.1996.d01-842.x.
33. Haytac MC, Ozcelik O, Mariotti A. Periodontal disease in men. Periodontol 2000. 2013; 61(1): 252-65. doi: 10.1111/j.1600-0757.2011.00410.x.
34. Orwoll ES, Chan BK, Lambert LC, Marshall LM, Lewis C, Phipps KR. Sex steroids, periodontal health, and tooth loss in older men. J Dent Res. 2009; 88(8): 704-8. doi: 10.1177/0022034509341013.
35. Raber-Durlacher J, Steenbergen T, Velden U, Graaf J, Abraham L. Experimental gingivitis during pregnancy and post-partum: Clinical, endocrinological, and microbiological aspects. J Clin Periodontol. 1994; 21(8): 549-58. Recuperado en: https://www.ncbi.nlm.nih.gov/ pubmed/7989619.
36. Tilakaratne A, Soory M, Ranasinghe A, Corea S, Ekanayake S, De Silva M. Periodontal disease status during pregnancy and 3 months post-partum, in a rural population of Sri-Lankan women. J Clin Periodontol. 2000; 27(10): 787-92. Recuperado en: https://www.ncbi.nlm.nih. gov/pubmed/11034128.
37. Goyal S, Gupta G, Thomas B, Bhat KM, Bhat GS. Stress and periodontal disease: The link and logic!! Ind Psychiatry J. 2013; 22(1): 4-11. doi: 10.4103/0972-6748.123585
38. González-Díaz ME, Toledo Pimentel B, Nazco Ríos C. Enfermedad periodontal y factores locales y sistémicos asociados. Rev Cubana Estomatol. 2002; 39(3): 374-395.
39. Broadbent JM, Williams KB, Thomson WM, Williams SM. Dental restorations: a risk factor for periodontal attachment loss? J Clin Periodontol. 2006; 33(11): 803-10. doi: 10.1111/j.1600-051X.2006.00988.x.
40. American Psychological Association (apa). Gender and stress. [Internet]. 2016 [citado el 14 de enero de 2018]. Recuperado en: http://www.apa.org/news/press/releases/stress/2010/ gender-stress.aspx
41. Bansal J, Bansal A, Shahi M, Kedige S, Narula R. Periodontal emotional stress syndrome: review of basic concepts, mechanism and management. Open Journal of Medical Psychology. 2014; 3(3): 250-61. Recuperado en: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=45252].
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spelling Mafla, Ana CristinaMafla, Ana CristinaPatiño, Mauricio Alexander15 (28)2020-01-24T15:45:29Z2020-01-24T15:45:29Z2019-03-201900-308010.16925/2357-4607.2019.01.03https://hdl.handle.net/20.500.12494/16334Mafla, A. C. y Patiño, M. A. (2019). Diferencias de sexo en severidad y factores de riesgo para caries dental y enfermedad periodontal. Rev Nac Odontol. 2019;15(28):1-19. Recuperado de: https://revistas.ucc.edu.co/index.php/od/article/view/2596/2629Introducción: el objetivo de este estudio fue determinar si existen diferencias de sexo en la severidad y factores de riesgo en la aparición de caries dental y enfermedad periodontal. Métodos: realizamos un estudio retrospectivo transversal a través de la revisión de historias clínicas de 621 pacientes de la clínica de la Facultad de Odontología de la Universidad Cooperativa de Colombia en Pasto, Colombia, durante 2008 y 2013. Se obtuvo el índice Copd e Icdas II para determinar la severidad de caries dental y el Índice Cpitn para evaluar enfermedad periodontal. Se realizó un análisis descriptivo y la asociación entre caries dental y enfermedad periodontal y los factores de riesgo se evaluaron mediante modelos lineales generalizados. Resultados: La media de Copd fue levemente mayor en mujeres (20,97±6,01) que en hombres (20,59±5,47) (P=0,191). Existió diferencia con respecto a dientes perdidos en hombres (4,85±4,54) y mujeres (6,12±5,64) (P=0,020). Encontramos que 12,8 % de hombres y 10,2 % de mujeres tenían bolsas periodontales ≥6mm (P=0,136). La presencia de diastemas (OR=2,881; IC al 95 %: 1,479-5,613; P=0,002) y sangrado gingival (OR=40,263; ic al 95 %: 7,851-206,484; P<0,001) se asociaron significativamente con la enfermedad periodontal en hombres y tener apiñamiento (OR=2,059; IC al 95 %: 1,387-3,055; P<0,001) y estar casada (OR=1,859; IC al 95 %: 1,046-3,304; P<0,034) influyó en esta enfermedad en mujeres. Conclusión: el diseño de estudio retrospectivo transversal es limitado, pero ofrece una vía prometedora para futuras exploraciones. Los resultados tienen implicaciones para la promoción de diferencias en sexo en cuidados de salud oral.Introduction: The objective of this study was to determine if there are sex differences in severity and risk factors in the development of dental caries and periodontal disease. Methods: We performed a retrospective cross-sectional study by reviewing medical records of 621 patients at the Faculty of Dentistry of the Universidad Cooperativa de Colombia in Pasto, Colombia, during 2008 and 2013. The COPD and ICDAS II index were obtained to determine the severity of dental caries and the CPITN index to evaluate periodontal disease. A descriptive analysis was performed, and the association between dental caries and periodontal disease as well as the risk factors were evaluated using generalized linear models. Results: the mean COPD was slightly higher in women (20.97 ± 6.01) than in men (20.59 ± 5.47) (P = 0.191). There was difference in teeth lost in males (4.85 ± 4.54) and females (6.12 ± 5.64) (P = 0.020). We found that 12.8% of men and 10.2% of women had periodontal pockets ≥6mm (P = 0.136). The presence of diastemas (OR = 2.881, 95% CI: 1.479-5.613, P = 0.002) and gingival bleeding (OR = 40.263, 95% CI: 7.851-206.484, P <0.001) were significantly associated with periodontal disease (OR = 2.859, 95% CI: 1.046-3.304, P <0.034) had an influence on this disease in women (OR = 2.059, 95% CI: 1.387-3.055, P <0.001). Conclusion: the retrospective cross-sectional study design is limited, but offers a promising avenue for future explorations. The results have implications for promoting differences in sex in oral health care.Introducción. -- Materiales y Métodos. -- Resultados. -- Discusión. -- Conclusioneshttps://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=00006766160000-0002-2805-7901https://scienti.minciencias.gov.co/gruplac/jsp/visualiza/visualizagr.jsp?nro=00000000002911ana.mafla@campusucc.edu.cohttps://scholar.google.com/citations?user=MSFc5YoAAAAJ&hl=es1-19Eliana PinedaUniversidad Cooperativa de Colombia, Facultad de Ciencias de la Salud, Odontología, PastoOdontologíaPastohttps://revistas.ucc.edu.co/index.php/od/article/view/2596/2629Revista Nacional de Odontología1. Legato MJ. Por qué los hombres nunca recuerdan y las mujeres nunca olvidan. Barcelona: Urano; 2006. 268 p.2. Gur RC, Mozley LH, Mozley PD, Resnick SM, Karp JS, A Alavi, et al. Sex differences in regional cerebral glucose metabolism during a resting state. Science. 1995; 267: 528-53. Recuperado en: https://www.ncbi.nlm.nih.gov/pubmed/7824953.3. Petersen PE. The world oral health report 2003: continuous improvement of oral health in the 21st century-the approach of the WHO Global Oral Health Programme. Community Dent Oral Epidemiol. 2003; 31(1): 3-23. Recuperado en: https://www.ncbi.nlm.nih.gov/ pubmed/15015736.4. Skinner J, Johnson G, Phelan C, Blinkhorn A. Dental caries in 14- and 15-year-olds in New South Wales, Australia. BMC Public Health. 2013; 13: 1060. doi: 10.1186/1471-2458-13-1060.5. Al-Darwish M, El Ansari W, Bener A. Prevalence of dental caries among 12-14 year old children in Qatar. Saudi Dent J. 2014; 26(3): 115-25. doi: 10.1016/j.sdentj.2014.03.006.6. Silva AE, Menezes AM, Assunção MC, Gonçalves H, Demarco FF, Vargas-Ferreira F, et al. Validation of self-reported information on dental caries in a birth cohort at 18 years of age. PLoS One. 2014; 9(9): 106382. doi: 10.1371/journal.pone.0106382.7. Žemaitienė M, Grigalauskienė R, Vasiliauskienė I, Saldūnaitė K, Razmienė J, Slabšinskienė E. Prevalence and severity of dental caries among 18-year-old Lithuanian adolescents. Medicina (Kaunas). 2016; 52(1): 54-60. doi: 10.1016/j.medici.2016.01.006.8. Kutesa A, Kasangaki A, Nkamba M, Muwazi L, Okullo I, Rwenyonyi CM. Prevalence and factors associated with dental caries among children and adults in selected districts in Uganda. Afr Health Sci. 2015; 15(4): 1302-7. doi: 10.4314/ahs.v15i4.33.9. Edman K, Öhrn K, Nordström B, Holmlund A, Hellberg D. Trends over 30 years in the prevalence and severity of alveolar bone loss and the influence of smoking and socio-economic factors - based on epidemiological surveys in Sweden 1983-2013. Int J Dent Hyg. 2015; 13(4): 283-91. doi: 10.1111/idh.12164.10. Aimetti M, Perotto S, Castiglione A, Mariani GM, Ferrarotti F, Romano F. Prevalence of periodontitis in an adult population from an urban area in North Italy: findings from a cross-sectional population-based epidemiological survey. J Clin Periodontol. 2015; 42(7): 622-31. doi: 10.1111/jcpe.12420.11. Torrungruang K, Tamsailom S, Rojanasomsith K, Sutdhibhisal S, Nisapakultorn K, Vanichjakvong O, et al. Risk indicators of periodontal disease in older Thai adults. J Periodontol. 2005; 76(4): 558-65.12. Balaji SK, Lavu V, Rao S. Chronic periodontitis prevalence and the inflammatory burden in a sample population from South India. Indian J Dent Res. 2018; 29(2): 254-9. doi: 10.4103/ijdr. IJDR_335_17.13. Idrees M, Hammad M, Faden A, Kujan O. Influence of body mass index on severity of dental caries: cross-sectional study in healthy adults. Ann Saudi Med. 2017; 37(6): 444-8. doi: 10.5144/0256-4947.2017.444.14. Ramírez-Puerta BS, Viñas-Sarmiento Y, López-Camacho V, Morales-Flórez JL. Línea de base en caries dental, Antioquia (Colombia), 2011. Rev Nac Odontol. 2012; 8(15): 9-20. doi: 10.16925.issn.1900-3080.15. Wang L, Cheng L, Yuan B, Hong X, Hu T. Association between socio-economic status and dental caries in elderly people in Sichuan Province, China: a cross-sectional study. BMJ Open. 2017; 7(9): 016557. doi: 10.1136/bmjopen-2017-016557.16. He S, Thomson WM. An oral epidemiological comparison of Chinese and New Zealand adults in 2 key age groups. Community Dent Oral Epidemiol. 2018; 46(2): 154-160. doi: 10.1111/ cdoe.12348.17. Lorenzo SM, Álvarez R, Andrade E, Piccardo V, Francia A, Massa Fernando, et al. Periodontal conditions and associated factors among adults and the elderly: findings from the first National Oral Health Survey in Uruguay. Cad. Saúde Pública. 2015; 31(11): 2425-36. doi: 10.1590/0102-311X0001211518. Vlassoff C. Gender differences in determinants and consequences of health and illness. J Health Popul Nutr. 2007; 25(1): 47-61. Recuperado en: https://www.ncbi.nlm.nih.gov/ pubmed/17615903.19. Vano M, Gennai S, Karapetsa D, Miceli M, Giuca MR, Gabriele M, et al. The influence of educational level and oral hygiene behaviours on DMFT index and CPITN index in an adult Italian population: An epidemiological study. Int J Dent Hyg. 2015; 13(2): 151-7. doi: 10.1111/idh.12098.20. Álvarez L, Liberman J, Abreu S, Mangarelli C, Correa MB, Demarco FF, et al. Dental caries in Uruguayan adults and elders: Findings from the first Uruguayan National Oral Health Survey. Cad Saude Publica. 2015; 31(8): 1663-72. doi: 10.1590/0102-311X00132214.21. Ajayi DM, Abiodun-Solanke IM, Gbadebo SO. A 5-year retrospective study of rampant dental caries among adult patients in a Nigerian Teaching Hospital. Indian J Dent Res. 2015; 26(3): 267-70. doi: 10.4103/0970-9290.162885.22. Rojas-Gutiérrez WJ, Vivares-Builes AM, Agudelo-Suárez AA. Caries dental e higiene bucal en escolares de la zona rural del municipio de Jericó, Antioquia, 2013. Rev Nac Odontol. 2013; 9(17): 27-34. doi: 10.16925/od.v9i17.569.23. Lukacs JR, Largaespada LL. Explaining sex differences in dental caries prevalence: saliva, hormones, and ‘‘Life-History’’ etiologies. American Journal of Human Biology. 2006; 18(4): 540-55. Recuperado en: https://www.ncbi.nlm.nih.gov/pubmed/16788889.24. Stock C, Jürges H, Shen J, Bozorgmehr K, Listl S. A comparison of tooth retention and replacement across 15 countries in the over-50s. Community Dent Oral Epidemiol. 2016; 44(3): 223-31. doi: 10.1111/cdoe.12209.25. Tsai SJ, Lin MS, Chiu WN, Jane SW, Tu LT, Chen MY. Factors associated with having less than 20 natural teeth in rural adults: a cross-sectional study. BMC Oral Health. 2015; 15(1): 158. doi: 10.1186/s12903-015-0147-y.26. Tiwari T, Scarbro S, Bryant LL, Puma J. Factors associated with tooth loss in older adults in rural Colorado. J Community Health. 2016; 41(3): 476-81. doi: 10.1007/s10900-015-0117-y.27. Roohafza H, Afghari P, Keshteli AH, Vali A, Shirani M, Adibi P, Afshar H. The relationship between tooth loss and psychological factors. Community Dent Health. 2015; 32(1): 16-9. Recuperado en: https://www.ncbi.nlm.nih.gov/pubmed/26263587.28. Bansal M, Mittal N, Singh TB. Assessment of the prevalence of periodontal diseases and treatment needs: A hospital-based study. J Indian Soc Periodontol. 2015; 19(2): 211-5. doi: 10.4103/0972-124X.145810.29. García-Conde G, Espinosa de Santillana A, Martínez F, Huerta-Herrera N, Islas-Márquez AJ, Medina-Solís E. Periodontal treatment needs in adults from Mixteca rural area in Puebla State, Mexico. Rev. Salud Pública. 2010; 12(4): 647-57. Recuperado en: https://www.ncbi.nlm.nih.gov/ pubmed/21340129.30. Oertelt-Prigione S. The influence of sex and gender on the immune response. Autoimmun Rev. 2012; 11(6-7): 479-85. doi: 10.1016/j.autrev.2011.11.022. Recuperado en: https://www. ncbi.nlm.nih.gov/pubmed/22155201.31. Whitacre CC, Reingold SC, O’Looney PA. A gender gap in autoimmunity. Science. 1999; 283(5406): 1277-1278. Recuperado en: https://www.ncbi.nlm.nih.gov/pubmed/1008493232. Kanda N, Tsuchida T, Tamaki K. Testosterone inhibits immunoglobulin production by human peripheral blood mononuclear cells. Clin Exp Immunol. 1996; 106(2): 410-5. doi: 10.1046/ j.1365-2249.1996.d01-842.x.33. Haytac MC, Ozcelik O, Mariotti A. Periodontal disease in men. Periodontol 2000. 2013; 61(1): 252-65. doi: 10.1111/j.1600-0757.2011.00410.x.34. Orwoll ES, Chan BK, Lambert LC, Marshall LM, Lewis C, Phipps KR. Sex steroids, periodontal health, and tooth loss in older men. J Dent Res. 2009; 88(8): 704-8. doi: 10.1177/0022034509341013.35. Raber-Durlacher J, Steenbergen T, Velden U, Graaf J, Abraham L. Experimental gingivitis during pregnancy and post-partum: Clinical, endocrinological, and microbiological aspects. J Clin Periodontol. 1994; 21(8): 549-58. Recuperado en: https://www.ncbi.nlm.nih.gov/ pubmed/7989619.36. Tilakaratne A, Soory M, Ranasinghe A, Corea S, Ekanayake S, De Silva M. Periodontal disease status during pregnancy and 3 months post-partum, in a rural population of Sri-Lankan women. J Clin Periodontol. 2000; 27(10): 787-92. Recuperado en: https://www.ncbi.nlm.nih. gov/pubmed/11034128.37. Goyal S, Gupta G, Thomas B, Bhat KM, Bhat GS. Stress and periodontal disease: The link and logic!! Ind Psychiatry J. 2013; 22(1): 4-11. doi: 10.4103/0972-6748.12358538. González-Díaz ME, Toledo Pimentel B, Nazco Ríos C. Enfermedad periodontal y factores locales y sistémicos asociados. Rev Cubana Estomatol. 2002; 39(3): 374-395.39. Broadbent JM, Williams KB, Thomson WM, Williams SM. Dental restorations: a risk factor for periodontal attachment loss? J Clin Periodontol. 2006; 33(11): 803-10. doi: 10.1111/j.1600-051X.2006.00988.x.40. American Psychological Association (apa). Gender and stress. [Internet]. 2016 [citado el 14 de enero de 2018]. Recuperado en: http://www.apa.org/news/press/releases/stress/2010/ gender-stress.aspx41. Bansal J, Bansal A, Shahi M, Kedige S, Narula R. Periodontal emotional stress syndrome: review of basic concepts, mechanism and management. Open Journal of Medical Psychology. 2014; 3(3): 250-61. 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