HLA in North Colombia Chimila Amerindians.
HLA-A,-B,-C,-DRB1 and -DQB1 alleles have been studied in Chimila Amerindians from Sabana de San Angel (North Colombian Coast) by using high resolution molecular typing. A frequent extended haplotype was found:HLA-A*24:02-B*51:10-C*15:02-BRB1*04:07-DQB1*03:02 (28.7%) which has also been described in...
- Autores:
-
Arnaiz Villena, Antonio
Palacio Grüber, Jose
Juarez, Ignacio
Hernandez Aguirre, Enio
Muñiz, Ester
Bayona, Brayan
Camposa, Cristina
Nietoa, Jorge
Martin Villa, Manuel
Silvera, Carlos
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2023
- Institución:
- Universidad Cooperativa de Colombia
- Repositorio:
- Repositorio UCC
- Idioma:
- OAI Identifier:
- oai:repository.ucc.edu.co:20.500.12494/50756
- Acceso en línea:
- https://doi.org/10.1016/j.humimm.2018.02.004
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85044515264&doi=10.1016%2fj.humimm.2018.02.004&partnerID=40&md5=b3c51e06066bc446dcb4f3be52f358ad
https://hdl.handle.net/20.500.12494/50756
- Palabra clave:
- AMERICAN INDIAN
ARTICLE
AUSTRALIA
BOLIVIA
COLOMBIA
EVOLUTION
GENE FREQUENCY
GENETICS
GEOGRAPHIC DISTRIBUTION
HAPLOTYPE
HAPLOTYPES
HLA A24 ANTIGEN
HLA ANTIGEN
HLA ANTIGENS
HLA B51 ANTIGEN
HLA DQB1 ANTIGEN
HUMAN
HUMANS
INDIANS, SOUTH AMERICAN
INDIGENOUS PEOPLE
MAORI (PEOPLE)
MEXICO
MOLECULAR TYPING
NEW CALEDONIAN
NEW ZEALAND
PERU
PRIORITY JOURNAL
TAIWAN
UNITED STATES
- Rights
- openAccess
- License
- http://purl.org/coar/access_right/c_abf2
Summary: | HLA-A,-B,-C,-DRB1 and -DQB1 alleles have been studied in Chimila Amerindians from Sabana de San Angel (North Colombian Coast) by using high resolution molecular typing. A frequent extended haplotype was found:HLA-A*24:02-B*51:10-C*15:02-BRB1*04:07-DQB1*03:02 (28.7%) which has also been described in Amerinndian Mayos Mexican population (Mexico, California Gulf, Pacific Ocean). Other haplotypes had already been found in Amerindians from Mexico (Pacific and Atlantic Coast), Peru (highlands and Amazon Basin), Bolivia and North USA. A geographic pattern according to HLA allele or haplotype frequencies is lacking in Amerindians, as already known. Also, five new extended haplotypes were found in Chimila Amerindians. Their HLA-A*24:02 high frequencies characteristic is shared with aboriginal populations of Taiwan; also, HLA-C*01:02 high frequencies are found in New Zealand Maoris, New Caledonians and Kimberly Aborigines from Australia. Finally, this study may show a model of evolutionary factors acting and rising one HLA allele frequency (-A*24:02), but not in others that belong to the same or different HLA loci. © 2018 |
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