Sulfasalazine as an Immunomodulator of the Inflammatory Process during HIV-1 Infection.

HIV-1 induces an uncontrolled inflammatory response of several immune components, such as inflammasomes. These molecular complexes, associated with Toll-like receptor (TLR) activity, induce the maturation and release of IL-1 and IL-18 and eventually induce pyroptosis. It has been previously demonstr...

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Autores:
Feria-Garzón, Manuel G
Rugeles, María T
Hernández López, Juan Carlos
Lujan, Jorge A
Taborda, Natalia A
Tipo de recurso:
Article of journal
Fecha de publicación:
2019
Institución:
Universidad Cooperativa de Colombia
Repositorio:
Repositorio UCC
Idioma:
OAI Identifier:
oai:repository.ucc.edu.co:20.500.12494/42850
Acceso en línea:
https://doi.org/10.5944/rppc.vol.21.num.3.2016.15711
https://www.scielo.br/scielo.php?pid=S0103-84782012000400017&script=sci_abstract
https://hdl.handle.net/20.500.12494/42850
Palabra clave:
HIV
inflammasomes
inflammation
sulfasalazine
toll-like receptors
Rights
closedAccess
License
http://purl.org/coar/access_right/c_14cb
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oai_identifier_str oai:repository.ucc.edu.co:20.500.12494/42850
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repository_id_str
spelling Feria-Garzón, Manuel GRugeles, María THernández López, Juan Carlos Lujan, Jorge ATaborda, Natalia A2021-12-16T22:16:34Z2021-12-16T22:16:34Z2019https://doi.org/10.5944/rppc.vol.21.num.3.2016.15711https://www.scielo.br/scielo.php?pid=S0103-84782012000400017&script=sci_abstract16616596https://hdl.handle.net/20.500.12494/42850Feria MG,Rugeles MT,Hernandez JC,Lujan JA,Taborda NA. Sulfasalazine as an Immunomodulator of the Inflammatory Process during HIV-1 Infection. Int. J. Mol. Sci. 2019. 20. (18):4476. .HIV-1 induces an uncontrolled inflammatory response of several immune components, such as inflammasomes. These molecular complexes, associated with Toll-like receptor (TLR) activity, induce the maturation and release of IL-1 and IL-18 and eventually induce pyroptosis. It has been previously demonstrated that HIV induces inflammasome activation, which is significantly lower in the gastrointestinal tissue and blood from people living with HIV-1 with spontaneous control of viral replication. Therefore, immunomodulatory agents could be useful in improving HIV prognosis.0000-0002-9200-5698juanc.hernandezl@campusucc.edu.co-Multidisciplinary Digital Publishing Institute (MDPI)HIVinflammasomesinflammationsulfasalazinetoll-like receptorsSulfasalazine as an Immunomodulator of the Inflammatory Process during HIV-1 Infection.Artículohttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionINT J MOL SCIinfo:eu-repo/semantics/closedAccesshttp://purl.org/coar/access_right/c_14cbPublication20.500.12494/42850oai:repository.ucc.edu.co:20.500.12494/428502024-08-20 16:22:24.7metadata.onlyhttps://repository.ucc.edu.coRepositorio Institucional Universidad Cooperativa de Colombiabdigital@metabiblioteca.com
dc.title.spa.fl_str_mv Sulfasalazine as an Immunomodulator of the Inflammatory Process during HIV-1 Infection.
title Sulfasalazine as an Immunomodulator of the Inflammatory Process during HIV-1 Infection.
spellingShingle Sulfasalazine as an Immunomodulator of the Inflammatory Process during HIV-1 Infection.
HIV
inflammasomes
inflammation
sulfasalazine
toll-like receptors
title_short Sulfasalazine as an Immunomodulator of the Inflammatory Process during HIV-1 Infection.
title_full Sulfasalazine as an Immunomodulator of the Inflammatory Process during HIV-1 Infection.
title_fullStr Sulfasalazine as an Immunomodulator of the Inflammatory Process during HIV-1 Infection.
title_full_unstemmed Sulfasalazine as an Immunomodulator of the Inflammatory Process during HIV-1 Infection.
title_sort Sulfasalazine as an Immunomodulator of the Inflammatory Process during HIV-1 Infection.
dc.creator.fl_str_mv Feria-Garzón, Manuel G
Rugeles, María T
Hernández López, Juan Carlos
Lujan, Jorge A
Taborda, Natalia A
dc.contributor.author.none.fl_str_mv Feria-Garzón, Manuel G
Rugeles, María T
Hernández López, Juan Carlos
Lujan, Jorge A
Taborda, Natalia A
dc.subject.spa.fl_str_mv HIV
inflammasomes
inflammation
sulfasalazine
toll-like receptors
topic HIV
inflammasomes
inflammation
sulfasalazine
toll-like receptors
description HIV-1 induces an uncontrolled inflammatory response of several immune components, such as inflammasomes. These molecular complexes, associated with Toll-like receptor (TLR) activity, induce the maturation and release of IL-1 and IL-18 and eventually induce pyroptosis. It has been previously demonstrated that HIV induces inflammasome activation, which is significantly lower in the gastrointestinal tissue and blood from people living with HIV-1 with spontaneous control of viral replication. Therefore, immunomodulatory agents could be useful in improving HIV prognosis.
publishDate 2019
dc.date.issued.none.fl_str_mv 2019
dc.date.accessioned.none.fl_str_mv 2021-12-16T22:16:34Z
dc.date.available.none.fl_str_mv 2021-12-16T22:16:34Z
dc.type.none.fl_str_mv Artículo
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.coar.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
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dc.type.driver.none.fl_str_mv info:eu-repo/semantics/article
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dc.type.version.none.fl_str_mv info:eu-repo/semantics/publishedVersion
format http://purl.org/coar/resource_type/c_6501
status_str publishedVersion
dc.identifier.none.fl_str_mv https://doi.org/10.5944/rppc.vol.21.num.3.2016.15711
https://www.scielo.br/scielo.php?pid=S0103-84782012000400017&script=sci_abstract
dc.identifier.issn.spa.fl_str_mv 16616596
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12494/42850
dc.identifier.bibliographicCitation.spa.fl_str_mv Feria MG,Rugeles MT,Hernandez JC,Lujan JA,Taborda NA. Sulfasalazine as an Immunomodulator of the Inflammatory Process during HIV-1 Infection. Int. J. Mol. Sci. 2019. 20. (18):4476. .
url https://doi.org/10.5944/rppc.vol.21.num.3.2016.15711
https://www.scielo.br/scielo.php?pid=S0103-84782012000400017&script=sci_abstract
https://hdl.handle.net/20.500.12494/42850
identifier_str_mv 16616596
Feria MG,Rugeles MT,Hernandez JC,Lujan JA,Taborda NA. Sulfasalazine as an Immunomodulator of the Inflammatory Process during HIV-1 Infection. Int. J. Mol. Sci. 2019. 20. (18):4476. .
dc.relation.ispartofjournal.spa.fl_str_mv INT J MOL SCI
dc.rights.accessrights.none.fl_str_mv info:eu-repo/semantics/closedAccess
dc.rights.coar.none.fl_str_mv http://purl.org/coar/access_right/c_14cb
eu_rights_str_mv closedAccess
rights_invalid_str_mv http://purl.org/coar/access_right/c_14cb
dc.format.extent.spa.fl_str_mv -
dc.publisher.spa.fl_str_mv Multidisciplinary Digital Publishing Institute (MDPI)
institution Universidad Cooperativa de Colombia
repository.name.fl_str_mv Repositorio Institucional Universidad Cooperativa de Colombia
repository.mail.fl_str_mv bdigital@metabiblioteca.com
_version_ 1814247247276146688

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