Time-course investigation of the gene expression profile during Fasciola hepatica infection: A microarray-based study

Fasciolosis is listed as one of the most important neglected tropical diseases according with the World Health Organization and is also considered as a reemerging disease in the human beings. Despite there are several studies describing the immune response induced by Fasciola hepatica in the mammali...

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Autores:
Rojas Caraballo, Jose Vicente
López-Abán J.
Fernández-Soto P.
Vicente B.
Collía F.
Muro A.
Tipo de recurso:
Article of journal
Fecha de publicación:
2015
Institución:
Universidad Cooperativa de Colombia
Repositorio:
Repositorio UCC
Idioma:
OAI Identifier:
oai:repository.ucc.edu.co:20.500.12494/41460
Acceso en línea:
https://doi.org/10.1016/j.molliq.2012.11.001
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85069887355&doi=10.1111%2fcid.12820&partnerID=40&md5=b176f90964e06234ee22b1c7d0cad748
https://hdl.handle.net/20.500.12494/41460
Palabra clave:
Fasciolosis
Microarrays
Gene expression
Immune response
Rights
closedAccess
License
http://purl.org/coar/access_right/c_14cb
Description
Summary:Fasciolosis is listed as one of the most important neglected tropical diseases according with the World Health Organization and is also considered as a reemerging disease in the human beings. Despite there are several studies describing the immune response induced by Fasciola hepatica in the mammalian host, investigations aimed at identifying the expression profile of genes involved in inducing hepatic injury are currently scarce. Data presented here belong to a time-course investigation of the gene expression profile in the liver of BALB/c mice infected with F. hepatica metacercariae at 7 and 21. days after experimental infection. The data published here have been deposited in NCBI's Gene Expression Omnibus and are accessible through GEO Series accession number GSE69588, previously published by Rojas-Caraballo et al. © 2015.