Aborto causado por rinotraqueítis infecciosa bovina (IBR)
La rinotraqueítis infecciosa bovina (IBR) es una enfermedad altamente contagiosa del ganado, el herpes virus bovino tipo 1, de la familia Herpesviridae, es un patógeno muy importante en el desarrollo de la enfermedad. Existen diferentes cepas que pueden causar distintas formas de la enfermedad: VHB-...
- Autores:
-
Diaz Peña, Daniel Alejandro
Rojas Varon, Carlos Andres
- Tipo de recurso:
- Trabajo de grado de pregrado
- Fecha de publicación:
- 2021
- Institución:
- Universidad Cooperativa de Colombia
- Repositorio:
- Repositorio UCC
- Idioma:
- OAI Identifier:
- oai:repository.ucc.edu.co:20.500.12494/34676
- Acceso en línea:
- https://hdl.handle.net/20.500.12494/34676
- Palabra clave:
- IBR
Aborto
Bovinos
Infección
VHB-1
TG 2021 MVZ 34676
IBR
Abortion
Cattle
Infection
VHB-1
- Rights
- openAccess
- License
- Atribución
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Aborto causado por rinotraqueítis infecciosa bovina (IBR) |
| title |
Aborto causado por rinotraqueítis infecciosa bovina (IBR) |
| spellingShingle |
Aborto causado por rinotraqueítis infecciosa bovina (IBR) IBR Aborto Bovinos Infección VHB-1 TG 2021 MVZ 34676 IBR Abortion Cattle Infection VHB-1 |
| title_short |
Aborto causado por rinotraqueítis infecciosa bovina (IBR) |
| title_full |
Aborto causado por rinotraqueítis infecciosa bovina (IBR) |
| title_fullStr |
Aborto causado por rinotraqueítis infecciosa bovina (IBR) |
| title_full_unstemmed |
Aborto causado por rinotraqueítis infecciosa bovina (IBR) |
| title_sort |
Aborto causado por rinotraqueítis infecciosa bovina (IBR) |
| dc.creator.fl_str_mv |
Diaz Peña, Daniel Alejandro Rojas Varon, Carlos Andres |
| dc.contributor.advisor.none.fl_str_mv |
Bonilla León, Lilian |
| dc.contributor.author.none.fl_str_mv |
Diaz Peña, Daniel Alejandro Rojas Varon, Carlos Andres |
| dc.subject.spa.fl_str_mv |
IBR Aborto Bovinos Infección VHB-1 |
| topic |
IBR Aborto Bovinos Infección VHB-1 TG 2021 MVZ 34676 IBR Abortion Cattle Infection VHB-1 |
| dc.subject.classification.spa.fl_str_mv |
TG 2021 MVZ 34676 |
| dc.subject.other.spa.fl_str_mv |
IBR Abortion Cattle Infection VHB-1 |
| description |
La rinotraqueítis infecciosa bovina (IBR) es una enfermedad altamente contagiosa del ganado, el herpes virus bovino tipo 1, de la familia Herpesviridae, es un patógeno muy importante en el desarrollo de la enfermedad. Existen diferentes cepas que pueden causar distintas formas de la enfermedad: VHB-1.1 son cepas específicas de enfermedades respiratorias agudas, mientras que, VHB -1. 2.a y VHB-1.2. b son cepas causantes de enfermedad respiratoria y enfermedad reproductiva, por otro lado, también son responsables de infertilidad, muerte embrionaria y abortos. VHB-1. 3.a y VHB-1.3. b son causantes de enfermedades encefálicas, menos comunes. La infección primaria se acompaña de diversas manifestaciones clínicas, como rinotraqueítis infecciosa bovina, aborto, vulvovaginitis pustulosa infecciosa e infección sistémica en neonatos. Cuando los animales sobreviven a la patogenicidad del virus, se establece una infección latente de por vida en los ganglios nerviosos sensoriales, haciendo que cualquier variación inmunológica permita la reinfección y por ende que estímulos de reactivación, pueden conducir a la reexcreción viral, responsable del mantenimiento de VHB-1 dentro de un rebaño, durante periodos extensos de tiempo. Al ser un virus altamente contagioso, la manera más efectiva y confiable para combatir la enfermedad dentro de los hatos ganaderos, es instaurar un correcto plan sanitario, que permita la debida inmunización de los animales, contra el virus, evitando así, las consecuencias productivas, económicas y sanitarias, la presente revisión bibliográfica busca recopilar la información más actualizada e importante al respecto de la IBR a nivel mundial como nacional, dándola la importancia requerida como causante de abortos en bovinos. |
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2021 |
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2021-06-21T16:28:42Z |
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2021-06-17 |
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Trabajo de grado - Pregrado |
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Diaz Peña, D. A. y Rojas Varón, C. A. (2021). Aborto causado por rinotraqueítis infecciosa bovina. (IBR). [Tesis de pregrado, Universidad Cooperativa de Colombia]. Repositorio Institucional UCC. http://hdl.handle.net/20.500.12494/34676 |
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| identifier_str_mv |
Diaz Peña, D. A. y Rojas Varón, C. A. (2021). Aborto causado por rinotraqueítis infecciosa bovina. (IBR). [Tesis de pregrado, Universidad Cooperativa de Colombia]. Repositorio Institucional UCC. http://hdl.handle.net/20.500.12494/34676 |
| dc.relation.references.spa.fl_str_mv |
Ackermann M, Engels M. Pro and contra IBR-eradication. Vet Microbiol. 2006;113(3-4 SPEC. ISS.):293–302. STRAUB OC. Infectious Bovine Rhinotracheitis Virus [Internet]. Virus Infections of Ruminants. Elsevier B.V.; 1990. 71–108 p. Available from: http://dx.doi.org/10.1016/B978-0-444-87312-5.50020-5 Muylkens B, Thiry J, Kirten P, Schynts F, Thiry E. Bovine herpesvirus 1 infection and infectious bovine rhinotracheitis. Vet Res. 2007;38(2):181–209. Newman LE. Infectious Bovine Rhinotracheitis and Bovine Virus Diarrhea. J Dairy Sci [Internet]. 1976;59(6):1179–83. Available from: http://dx.doi.org/10.3168/jds.S0022-0302(76)84342-1 Zapata JC, Ossa JE, Zuluaga FN. Actualización de los viejos enigmas y visión de futuro de la RIB en Colombia. 2002;15:155–9. Wiedmamf M, Brando&’ R, Wagnera P, Dubovib EJ, Batta CA. Virological Methods Detection of bovine herpesvirus-l in bovine semen by a nested PCR assay. J Virol Methods. 1993;44:44. Wentink GH, van Oirschot JT, Verhoeff J. Risk of infection with bovine herpes virus 1 (BHV1): a review. Vet Q. 1993;15(1):30–3. Thiry J, Keuser V, Muylkens B, Meurens F, Gogev S, Vanderplasschen A, et al. Ruminant alphaherpesviruses related to bovine herpesvirus 1. Vet Res [Internet]. 2006;37:169–90. Available from: http://dx.doi.org/10.1051/vetres:2005052 Ollivier FJ, Brooks DE, Kallberg ME, Komaromy AM, Lassaline ME, Andrew SE, Gelatt KN, Stevens GR, Blalock TD, van Setten GB SG. Evaluation of various compounds to inhibit activity of matrix metalloproteinases in the tear film of horses with ulcerative keratitis. Am J Vet Res. 2003;64(9):1081– Straub OC. Infectious bovine rhinotracheitis virus. In: Dinter Z and Morein B (eds) Virus Infections ofRuminants. Oxford Elsevier Sci Publ BV, pp. 1990;71–108. Nardelli S, Farina G, Lucchini R, Valorz C, Moresco A, Dal Zotto R, et al. Dynamics of infection and immunity in a dairy cattle population undergoing an eradication programme for Infectious Bovine Rhinotracheitis (IBR). Prev Vet Med. 2008;85(1–2):68–80. A. E, Metzler; A. A SME. Archives of Virology Bovine Herpesvirus 1 : Molecular and Antigenic Characteristics of Variant Viruses Isolated from Calves with Neurological Disease. Inst Virol Univ Ziirieh, Ziirich, Switz. 1986;217:205–17. Zapata J, Ossa J, Bedoya G, Zuluaga F. Rinotraqueitis Infecciosa Bovina (RIB). Caracterización Molecular de una cepa Colombiana de Herpesvirus Bovino tipo 1. Rev Colomb Ciencias Pecu. 2002;15(1):92–9. Nettleton P, Russell G. Update on infectious bovine rhinotracheitis. In Pract. 2017;39(6):255–72. Durham PJK. Infectious bovine rhinotracheitis virus and its role in bovine abortion. N Z Vet J. 1974;22(10):175–80. Steukers L, Vandekerckhove AP, Van Den Broeck W, Glorieux S, Nauwynck HJ. Comparative analysis of replication characteristics of BoHV-1 subtypes in bovine respiratory and genital mucosa explants: A phylogenetic enlightenment. Vet Res. 2011;42(1):1–11. Dağalp SB, Babaoglu AR, Doğan F, Farzani TA, Alkan F. An assessment of bovine herpes virus 4 as a causative agent in abortions and neonatal death. Onderstepoort J Vet Res. 2020;87(1):1–5. Santman-Berends IMGA, Mars MH, Waldeck HWF, van Duijn L, Wever P, van den Broek KWH, et al. Quantification of the probability of reintroduction of IBR in the Netherlands through cattle imports. Prev Vet Med [Internet]. 2018;150(January):168–75. Available from: http://dx.doi.org/10.1016/j.prevetmed.2017.08.024 Sánchez T. G, Benito Z. A, Rivera G. H. Seroprevalencia Del Virus De La Rinotraqueitis Infecciosa Bovina En Ganado Lechero Del Valle De Lima. Rev Investig Vet del Perú. 2013;14(1):54–60. Raaperi K, Orro T, Viltrop A. Epidemiology and control of bovine herpesvirus 1 infection in Europe. Vet J [Internet]. 2014;201(3):249–56. Available from: http://dx.doi.org/10.1016/j.tvjl.2014.05.040 Handa Gustiawan. SEROPREVALENCIA DE LA RINOTRAQUEITIS INFECCIOSA BOVINA EN LOS MUNICIPIOS DE PATÍA Y MERCADERES – CAUCA. Αγαη. 2019;8(5):55. Betancur H C, González T M, Reza G. L. Seroepidemiología de la rinotraqueitis infecciosa bovina en el municipio de Montería, Colombia. Rev Mvz Córdoba. 2006;11(2):830–6. Ochoa X, Orbegozo M, Manrique-Abril F, Martín Pulido M, Ospina J. Seroprevalence of infectious bovine rhinotracheitis in dairy herds Toca - Boyaca. Rev MVZ Cordoba. 2012;17(2):2974–82. Piedrahita D, V RGV. Detección Y Caracterización Por Métodos Moleculares De Aislamientos Colombianos De Herpesvirus Bovino Tipo 1 Detection and Characterization By Molecular Methods of Colombian Isolations of Bovine Herpesvirus Type 1. 2005;120–7 Kaashoek M.J., Straver P.H., Van R.E., Quak J. van OJ. Virulence, im- munogenicity and reactivation of seven bovine herpesvirus 1.1 strains: clinical and virological aspects. Vet Rec. 1996;139:416–21. Nandi S, Kumar M, Manohar M, Chauhan RS. Bovine herpes virus infections in cattle. Anim Health Res Rev. 2009;10(1):85–98. Kamaraj G, Lakshmi Narasu M, Srinivasan VA. Validation of betapropiolactone (BPL) as an inactivant for infectious bovine rhinotracheitis (IBR) virus. Res Vet Sci. 2008;85(3):589–94. Hammerschmidt W, Lurz R, Ludwig H, Buhk HJ. Recombination of genomic terminus of bovine herpesvirus type 1 with cellular DNA. J Gen Virol. 1990;71(9):2043–51. Penny CD. Investigation of respiratory disease in IBR vaccinated dairy herds. Vet Rec. 2013;172(4):109–10. Zimmerman AD, Buterbaugh RE, Herbert JM, Hass JM, Frank NE, Luempert LG, et al. Efficacy of bovine herpesvirus-1 inactivated vaccine against abortion and stillbirth in pregnant heifers. J Am Vet Med Assoc. 2007;231(9):1386–9. Deas W. Non-brucella abortion in. Large Anim Clin. 1981;(March). Muylkens B., Meurens F., Schynts F., Farnir F., Pourchet A., Bardiau M., Gogev S., Thiry J., Cuisenaire A., Vanderplasschen A. TE. Intraspecific bovine herpesvirus 1 recombinants carry- ing glycoprotein E deletion as a vaccine marker are virulent in cattle, J. Gen Viro. 2006;87:2149–2154. Enrique Barrera Calva1 ACI y F de J de la O, Ramírez1. Diagnóstico de Rinotraqueítis Infecciosa Bovina mediante Inmunoperoxidasa (Diagnostic of Infectious Bovine Rhinotracheítis by means of Inmunoperoxidase). Redvet. 2005;V(11). Miller J.M., Whetstone C.A. V der MM. Abortifacient property of bovine herpesvirus type 1 isolates that rep- resent three subtypes determined by restriction endonuclease analysis of viral DNA. Am J Vet Res. 1991;52:458–461. Iga T. pathology of bovine abortion and newborn calf death caused by dual infection with chlamydia psittaci and infectious bovine rhinotracheitis virus. Chem Pharm Bull [Internet]. 1971;19(2):273–81. Available from: http://www.mendeley.com/research/geology-volcanic-history-eruptive-style-yakedake-volcano-group-central-japan/ Engels M, Ackermann M. Pathogenesis of ruminant herpesvirus infections. Vet Microbiol. 1996;53(1–2):3–15. Smith KC. Herpesviral abortion in domestic animals. Vet J. 1997;153(3):253–68. Graham DA. Bovine herpes virus-1 (BoHV-1) in cattle-a review with emphasis on reproductive impacts and the emergence of infection in Ireland and the United Kingdom. Ir Vet J. 2013;66(1). N. Lapierre SL et GM. L’INFLUENCE DE L’AGE DES VEAUX SUR UN PROGRAMME DE VACCINATION INTRA-NASALE CONTRE LA RHINO-TRACHEITE INFECTIEUSE BOVINE ET LE PARA-INFLUENZA 3. 1975;16(1). Van Oirschot JT. Bovine herpesvirus 1 in semen of bulls and the risk of transmission: a brief review. Vet Q. 1995;17:29–33. Edwards S NR and WH. The virulence of British isolates of BHV-1 in relationship to viral genotype. Br Vet J. 1991;47:216–31. Muratore E, Bertolotti L, Nogarol C, Caruso C, Lucchese L, Iotti B, et al. Surveillance of Infectious Bovine Rhinotracheitis in marker-vaccinated dairy herds: Application of a recombinant gE ELISA on bulk milk samples. Vet Immunol Immunopathol [Internet]. 2017;185:1–6. Available from: http://dx.doi.org/10.1016/j.vetimm.2017.01.003 Newcomer BW, Givens D. Diagnosis and Control of Viral Diseases of Reproductive Importance: Infectious Bovine Rhinotracheitis and Bovine Viral Diarrhea. Vet Clin North Am - Food Anim Pract. 2016;32(2):425–41. Mahajan V, Banga HS, Deka D, Filia G, Gupta A. Comparison of diagnostic tests for diagnosis of infectious bovine rhinotracheitis in natural cases of bovine abortion. J Comp Pathol [Internet]. 2013;149(4):391–401. Available from: http://dx.doi.org/10.1016/j.jcpa.2013.05.002 Bertolotti L, Muratore E, Nogarol C, Caruso C, Lucchese L, Profiti M, et al. Development and validation of an indirect ELISA as a confirmatory test for surveillance of infectious bovine rhinotracheitis in vaccinated herds. BMC Vet Res [Internet]. 2015;11(1):5–11. Available from: http://dx.doi.org/10.1186/s12917-015-0612-5 Zambrano Varon JL. Salud de hato definición y estrategias para el establecimiento de programas de medicina veterinaria preventiva. Rev la Fac Med Vet y Zootec. 2009;56(3):147–62. Newcomer BW, Cofield LG, Walz PH, Givens MD. Prevention of abortion in cattle following vaccination against bovine herpesvirus 1: A meta-analysis. Prev Vet Med [Internet]. 2017;138:1–8. Available from: http://dx.doi.org/10.1016/j.prevetmed.2017.01.005 Duque D, Ramón Estévez J, Abreu Velez A, Moncada Velasquez M, Durango J, Molina Palacios D. Aspectos sobre Rinotraqueítis Infecciosa Bovina. 2014;3(1). Ruiz-Saenz J, Jaime J, Vera V. Vacunas contra el herpesvirus bovino-1: Una mirada desde el pasado hacia el futuro de la inmunización. Acta Biol Colomb. 2009;14(2):3–20. Rocha MA, Barbosa EF, Guedes RMC, Lage AP, Leite RC, Gouveia AMG. Detection of BHV-1 in a Naturally Infected Bovine Fetus by a Nested PCR assay. Vet Res Commun. 1999;23(2):133–41. |
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Bonilla León, LilianDiaz Peña, Daniel AlejandroRojas Varon, Carlos Andres2021-06-21T16:28:42Z2021-06-21T16:28:42Z2021-06-17https://hdl.handle.net/20.500.12494/34676Diaz Peña, D. A. y Rojas Varón, C. A. (2021). Aborto causado por rinotraqueítis infecciosa bovina. (IBR). [Tesis de pregrado, Universidad Cooperativa de Colombia]. Repositorio Institucional UCC. http://hdl.handle.net/20.500.12494/34676La rinotraqueítis infecciosa bovina (IBR) es una enfermedad altamente contagiosa del ganado, el herpes virus bovino tipo 1, de la familia Herpesviridae, es un patógeno muy importante en el desarrollo de la enfermedad. Existen diferentes cepas que pueden causar distintas formas de la enfermedad: VHB-1.1 son cepas específicas de enfermedades respiratorias agudas, mientras que, VHB -1. 2.a y VHB-1.2. b son cepas causantes de enfermedad respiratoria y enfermedad reproductiva, por otro lado, también son responsables de infertilidad, muerte embrionaria y abortos. VHB-1. 3.a y VHB-1.3. b son causantes de enfermedades encefálicas, menos comunes. La infección primaria se acompaña de diversas manifestaciones clínicas, como rinotraqueítis infecciosa bovina, aborto, vulvovaginitis pustulosa infecciosa e infección sistémica en neonatos. Cuando los animales sobreviven a la patogenicidad del virus, se establece una infección latente de por vida en los ganglios nerviosos sensoriales, haciendo que cualquier variación inmunológica permita la reinfección y por ende que estímulos de reactivación, pueden conducir a la reexcreción viral, responsable del mantenimiento de VHB-1 dentro de un rebaño, durante periodos extensos de tiempo. Al ser un virus altamente contagioso, la manera más efectiva y confiable para combatir la enfermedad dentro de los hatos ganaderos, es instaurar un correcto plan sanitario, que permita la debida inmunización de los animales, contra el virus, evitando así, las consecuencias productivas, económicas y sanitarias, la presente revisión bibliográfica busca recopilar la información más actualizada e importante al respecto de la IBR a nivel mundial como nacional, dándola la importancia requerida como causante de abortos en bovinos.Infectious bovine rhinotracheitis (IBR) is a highly contagious disease of cattle. Bovine herpesvirus type 1, of the Herpesviridae family, is a very important pathogen in the development of the disease. There are different strains that can cause different forms of the disease: HBV-1.1 are strains specific to acute respiratory disease, while, HBV-1.2.a and HBV-1.2.b are strains causing respiratory disease and reproductive disease, on the other hand, they are also responsible for infertility, embryonic death and abortions. HBV-1. 3.a and HBV-1.3.b are less common causes of encephalic disease. Primary infection is accompanied by various clinical manifestations, such as infectious bovine rhinotracheitis, abortion, infectious pustular vulvovaginitis and systemic infection in neonates. When animals survive the pathogenicity of the virus, a lifelong latent infection is established in the sensory nerve ganglia, causing any immunological variation to allow reinfection and thus reactivation stimuli can lead to viral re-excretion, responsible for the maintenance of HBV-1 within a herd for extended periods of time. Being a highly contagious virus, the most effective and reliable way to combat the disease in cattle herds is to establish a correct sanitary plan that allows the proper immunization of animals against the virus, thus avoiding the productive, economic and sanitary consequences. The present bibliographic review seeks to compile the most updated and important information on IBR worldwide and nationally, giving it the required importance as a cause of abortions in cattle.daniel.diazp@campusucc.edu.cocarlos.rojasva@campusucc.edu.co24 p.Universidad Cooperativa de Colombia, Facultad de Ciencias de la Salud, Medicina Veterinaría y Zootecnia, IbaguéMedicina veterinaria y zootecniaIbaguéIBRAbortoBovinosInfecciónVHB-1TG 2021 MVZ 34676IBRAbortionCattleInfectionVHB-1Aborto causado por rinotraqueítis infecciosa bovina (IBR)Trabajo de grado - Pregradohttp://purl.org/coar/resource_type/c_7a1finfo:eu-repo/semantics/bachelorThesisinfo:eu-repo/semantics/acceptedVersionAtribucióninfo:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Ackermann M, Engels M. Pro and contra IBR-eradication. Vet Microbiol. 2006;113(3-4 SPEC. ISS.):293–302.STRAUB OC. Infectious Bovine Rhinotracheitis Virus [Internet]. Virus Infections of Ruminants. Elsevier B.V.; 1990. 71–108 p. Available from: http://dx.doi.org/10.1016/B978-0-444-87312-5.50020-5Muylkens B, Thiry J, Kirten P, Schynts F, Thiry E. Bovine herpesvirus 1 infection and infectious bovine rhinotracheitis. Vet Res. 2007;38(2):181–209.Newman LE. Infectious Bovine Rhinotracheitis and Bovine Virus Diarrhea. J Dairy Sci [Internet]. 1976;59(6):1179–83. Available from: http://dx.doi.org/10.3168/jds.S0022-0302(76)84342-1Zapata JC, Ossa JE, Zuluaga FN. Actualización de los viejos enigmas y visión de futuro de la RIB en Colombia. 2002;15:155–9.Wiedmamf M, Brando&’ R, Wagnera P, Dubovib EJ, Batta CA. Virological Methods Detection of bovine herpesvirus-l in bovine semen by a nested PCR assay. J Virol Methods. 1993;44:44.Wentink GH, van Oirschot JT, Verhoeff J. Risk of infection with bovine herpes virus 1 (BHV1): a review. Vet Q. 1993;15(1):30–3.Thiry J, Keuser V, Muylkens B, Meurens F, Gogev S, Vanderplasschen A, et al. Ruminant alphaherpesviruses related to bovine herpesvirus 1. Vet Res [Internet]. 2006;37:169–90. Available from: http://dx.doi.org/10.1051/vetres:2005052Ollivier FJ, Brooks DE, Kallberg ME, Komaromy AM, Lassaline ME, Andrew SE, Gelatt KN, Stevens GR, Blalock TD, van Setten GB SG. Evaluation of various compounds to inhibit activity of matrix metalloproteinases in the tear film of horses with ulcerative keratitis. Am J Vet Res. 2003;64(9):1081–Straub OC. Infectious bovine rhinotracheitis virus. In: Dinter Z and Morein B (eds) Virus Infections ofRuminants. Oxford Elsevier Sci Publ BV, pp. 1990;71–108.Nardelli S, Farina G, Lucchini R, Valorz C, Moresco A, Dal Zotto R, et al. Dynamics of infection and immunity in a dairy cattle population undergoing an eradication programme for Infectious Bovine Rhinotracheitis (IBR). Prev Vet Med. 2008;85(1–2):68–80.A. E, Metzler; A. A SME. Archives of Virology Bovine Herpesvirus 1 : Molecular and Antigenic Characteristics of Variant Viruses Isolated from Calves with Neurological Disease. Inst Virol Univ Ziirieh, Ziirich, Switz. 1986;217:205–17.Zapata J, Ossa J, Bedoya G, Zuluaga F. Rinotraqueitis Infecciosa Bovina (RIB). Caracterización Molecular de una cepa Colombiana de Herpesvirus Bovino tipo 1. Rev Colomb Ciencias Pecu. 2002;15(1):92–9.Nettleton P, Russell G. Update on infectious bovine rhinotracheitis. In Pract. 2017;39(6):255–72.Durham PJK. Infectious bovine rhinotracheitis virus and its role in bovine abortion. N Z Vet J. 1974;22(10):175–80.Steukers L, Vandekerckhove AP, Van Den Broeck W, Glorieux S, Nauwynck HJ. Comparative analysis of replication characteristics of BoHV-1 subtypes in bovine respiratory and genital mucosa explants: A phylogenetic enlightenment. Vet Res. 2011;42(1):1–11.Dağalp SB, Babaoglu AR, Doğan F, Farzani TA, Alkan F. An assessment of bovine herpes virus 4 as a causative agent in abortions and neonatal death. Onderstepoort J Vet Res. 2020;87(1):1–5.Santman-Berends IMGA, Mars MH, Waldeck HWF, van Duijn L, Wever P, van den Broek KWH, et al. Quantification of the probability of reintroduction of IBR in the Netherlands through cattle imports. Prev Vet Med [Internet]. 2018;150(January):168–75. Available from: http://dx.doi.org/10.1016/j.prevetmed.2017.08.024Sánchez T. G, Benito Z. A, Rivera G. H. Seroprevalencia Del Virus De La Rinotraqueitis Infecciosa Bovina En Ganado Lechero Del Valle De Lima. Rev Investig Vet del Perú. 2013;14(1):54–60.Raaperi K, Orro T, Viltrop A. Epidemiology and control of bovine herpesvirus 1 infection in Europe. Vet J [Internet]. 2014;201(3):249–56. Available from: http://dx.doi.org/10.1016/j.tvjl.2014.05.040Handa Gustiawan. SEROPREVALENCIA DE LA RINOTRAQUEITIS INFECCIOSA BOVINA EN LOS MUNICIPIOS DE PATÍA Y MERCADERES – CAUCA. Αγαη. 2019;8(5):55.Betancur H C, González T M, Reza G. L. Seroepidemiología de la rinotraqueitis infecciosa bovina en el municipio de Montería, Colombia. Rev Mvz Córdoba. 2006;11(2):830–6.Ochoa X, Orbegozo M, Manrique-Abril F, Martín Pulido M, Ospina J. Seroprevalence of infectious bovine rhinotracheitis in dairy herds Toca - Boyaca. Rev MVZ Cordoba. 2012;17(2):2974–82.Piedrahita D, V RGV. Detección Y Caracterización Por Métodos Moleculares De Aislamientos Colombianos De Herpesvirus Bovino Tipo 1 Detection and Characterization By Molecular Methods of Colombian Isolations of Bovine Herpesvirus Type 1. 2005;120–7Kaashoek M.J., Straver P.H., Van R.E., Quak J. van OJ. Virulence, im- munogenicity and reactivation of seven bovine herpesvirus 1.1 strains: clinical and virological aspects. Vet Rec. 1996;139:416–21.Nandi S, Kumar M, Manohar M, Chauhan RS. Bovine herpes virus infections in cattle. Anim Health Res Rev. 2009;10(1):85–98.Kamaraj G, Lakshmi Narasu M, Srinivasan VA. Validation of betapropiolactone (BPL) as an inactivant for infectious bovine rhinotracheitis (IBR) virus. Res Vet Sci. 2008;85(3):589–94.Hammerschmidt W, Lurz R, Ludwig H, Buhk HJ. Recombination of genomic terminus of bovine herpesvirus type 1 with cellular DNA. J Gen Virol. 1990;71(9):2043–51.Penny CD. Investigation of respiratory disease in IBR vaccinated dairy herds. Vet Rec. 2013;172(4):109–10.Zimmerman AD, Buterbaugh RE, Herbert JM, Hass JM, Frank NE, Luempert LG, et al. Efficacy of bovine herpesvirus-1 inactivated vaccine against abortion and stillbirth in pregnant heifers. J Am Vet Med Assoc. 2007;231(9):1386–9.Deas W. Non-brucella abortion in. Large Anim Clin. 1981;(March).Muylkens B., Meurens F., Schynts F., Farnir F., Pourchet A., Bardiau M., Gogev S., Thiry J., Cuisenaire A., Vanderplasschen A. TE. Intraspecific bovine herpesvirus 1 recombinants carry- ing glycoprotein E deletion as a vaccine marker are virulent in cattle, J. Gen Viro. 2006;87:2149–2154.Enrique Barrera Calva1 ACI y F de J de la O, Ramírez1. Diagnóstico de Rinotraqueítis Infecciosa Bovina mediante Inmunoperoxidasa (Diagnostic of Infectious Bovine Rhinotracheítis by means of Inmunoperoxidase). Redvet. 2005;V(11).Miller J.M., Whetstone C.A. V der MM. Abortifacient property of bovine herpesvirus type 1 isolates that rep- resent three subtypes determined by restriction endonuclease analysis of viral DNA. Am J Vet Res. 1991;52:458–461.Iga T. pathology of bovine abortion and newborn calf death caused by dual infection with chlamydia psittaci and infectious bovine rhinotracheitis virus. Chem Pharm Bull [Internet]. 1971;19(2):273–81. Available from: http://www.mendeley.com/research/geology-volcanic-history-eruptive-style-yakedake-volcano-group-central-japan/Engels M, Ackermann M. Pathogenesis of ruminant herpesvirus infections. Vet Microbiol. 1996;53(1–2):3–15.Smith KC. Herpesviral abortion in domestic animals. Vet J. 1997;153(3):253–68.Graham DA. Bovine herpes virus-1 (BoHV-1) in cattle-a review with emphasis on reproductive impacts and the emergence of infection in Ireland and the United Kingdom. Ir Vet J. 2013;66(1).N. Lapierre SL et GM. L’INFLUENCE DE L’AGE DES VEAUX SUR UN PROGRAMME DE VACCINATION INTRA-NASALE CONTRE LA RHINO-TRACHEITE INFECTIEUSE BOVINE ET LE PARA-INFLUENZA 3. 1975;16(1).Van Oirschot JT. Bovine herpesvirus 1 in semen of bulls and the risk of transmission: a brief review. Vet Q. 1995;17:29–33.Edwards S NR and WH. The virulence of British isolates of BHV-1 in relationship to viral genotype. Br Vet J. 1991;47:216–31.Muratore E, Bertolotti L, Nogarol C, Caruso C, Lucchese L, Iotti B, et al. Surveillance of Infectious Bovine Rhinotracheitis in marker-vaccinated dairy herds: Application of a recombinant gE ELISA on bulk milk samples. Vet Immunol Immunopathol [Internet]. 2017;185:1–6. Available from: http://dx.doi.org/10.1016/j.vetimm.2017.01.003Newcomer BW, Givens D. Diagnosis and Control of Viral Diseases of Reproductive Importance: Infectious Bovine Rhinotracheitis and Bovine Viral Diarrhea. Vet Clin North Am - Food Anim Pract. 2016;32(2):425–41.Mahajan V, Banga HS, Deka D, Filia G, Gupta A. Comparison of diagnostic tests for diagnosis of infectious bovine rhinotracheitis in natural cases of bovine abortion. J Comp Pathol [Internet]. 2013;149(4):391–401. Available from: http://dx.doi.org/10.1016/j.jcpa.2013.05.002Bertolotti L, Muratore E, Nogarol C, Caruso C, Lucchese L, Profiti M, et al. Development and validation of an indirect ELISA as a confirmatory test for surveillance of infectious bovine rhinotracheitis in vaccinated herds. BMC Vet Res [Internet]. 2015;11(1):5–11. Available from: http://dx.doi.org/10.1186/s12917-015-0612-5Zambrano Varon JL. Salud de hato definición y estrategias para el establecimiento de programas de medicina veterinaria preventiva. Rev la Fac Med Vet y Zootec. 2009;56(3):147–62.Newcomer BW, Cofield LG, Walz PH, Givens MD. Prevention of abortion in cattle following vaccination against bovine herpesvirus 1: A meta-analysis. Prev Vet Med [Internet]. 2017;138:1–8. Available from: http://dx.doi.org/10.1016/j.prevetmed.2017.01.005Duque D, Ramón Estévez J, Abreu Velez A, Moncada Velasquez M, Durango J, Molina Palacios D. Aspectos sobre Rinotraqueítis Infecciosa Bovina. 2014;3(1).Ruiz-Saenz J, Jaime J, Vera V. Vacunas contra el herpesvirus bovino-1: Una mirada desde el pasado hacia el futuro de la inmunización. Acta Biol Colomb. 2009;14(2):3–20.Rocha MA, Barbosa EF, Guedes RMC, Lage AP, Leite RC, Gouveia AMG. Detection of BHV-1 in a Naturally Infected Bovine Fetus by a Nested PCR assay. 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