Solution thermodynamics and preferential solvation of sulfamethazine in (methanol + water) mixtures
The solubility of sulfamethazine (SMT) in {methanol (1) + water (2)} co-solvent mixtures was determined at five different temperatures from (293.15 to 313.15) K. The sulfonamide exhibited its highest mole fraction solubility in pure methanol (d1 = 29.6 MPa1/2) and its lowest mole fraction solubility...
- Autores:
-
Delgado, Daniel ricardo
Almanza O.A.
Martínez F.
Peña M.A.
Jouyban A.
Acree W.E.
Jr.
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2023
- Institución:
- Universidad Cooperativa de Colombia
- Repositorio:
- Repositorio UCC
- Idioma:
- OAI Identifier:
- oai:repository.ucc.edu.co:20.500.12494/49561
- Acceso en línea:
- https://doi.org/10.1016/j.jct.2016.02.002
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84958568243&doi=10.1016%2fj.jct.2016.02.002&partnerID=40&md5=81f4b62178ba7fcb1f827db4f14a587b
https://hdl.handle.net/20.500.12494/49561
- Palabra clave:
- ACTIVITY COEFFICIENTS
ENTHALPY
ENTHALPY-ENTROPY RELATIONSHIP
ENTROPY
GIBBS FREE ENERGY
JOUYBAN-ACREE MODEL
KIRKWOOD-BUFF INTEGRALS
METHANOL
MIXING
MIXTURES
ORGANIC SOLVENTS
PREFERENTIAL SOLVATION
SOLUBILITY
SOLUTION THERMODYNAMICS
SOLVATION
SULFAMETHAZINE
SULFUR COMPOUNDS
THERMODYNAMIC FUNCTIONS
THERMODYNAMIC QUANTITIES
THERMODYNAMICS
- Rights
- openAccess
- License
- http://purl.org/coar/access_right/c_abf2
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Delgado, Daniel ricardoAlmanza O.A.Martínez F.Peña M.A.Jouyban A.Acree W.E.Jr.2023-05-24T16:21:31Z2023-05-24T16:21:31Z01/01/2016https://doi.org/10.1016/j.jct.2016.02.002https://www.scopus.com/inward/record.uri?eid=2-s2.0-84958568243&doi=10.1016%2fj.jct.2016.02.002&partnerID=40&md5=81f4b62178ba7fcb1f827db4f14a587b00219614https://hdl.handle.net/20.500.12494/49561Delgado Daniel ricardo,Almanza O.A.,Martínez F.,Peña M.A.,Jouyban A.,Acree W.E.,Jr..Solution thermodynamics and preferential solvation of sulfamethazine in (methanol + water) mixtures.J CHEM THERMODYN. 2016. 97.:p. 264-276The solubility of sulfamethazine (SMT) in {methanol (1) + water (2)} co-solvent mixtures was determined at five different temperatures from (293.15 to 313.15) K. The sulfonamide exhibited its highest mole fraction solubility in pure methanol (d1 = 29.6 MPa1/2) and its lowest mole fraction solubility in water (d2 = 47.8 MPa1/2) at each of the five temperatures studied. The Jouyban-Acree model was used to correlate/predict the solubility values. The respective apparent thermodynamic functions Gibbs energy, enthalpy, and entropy of solution were obtained from the solubility data through the van't Hoff and Gibbs equations. Apparent thermodynamic quantities of mixing were also calculated for this drug using values of the ideal solubility reported in the literature. A non-linear enthalpy-entropy relationship was noted for SMT in plots of both the enthalpy vs. Gibbs energy of mixing and the enthalpy vs. entropy of mixing. These plots suggest two different trends according to the slopes obtained when the composition of the mixtures changes. Accordingly, the mechanism for SMT transfer processes in water-rich mixtures from water to the mixture with 0.70 in mass fraction of methanol is entropy driven. Conversely, the mechanism is enthalpy driven in mixtures whenever the methanol composition exceeds 0.70 mol fraction. An inverse Kirkwood-Buff integral analysis of the preferential solvation of SMT indicated that the drug is preferentially solvated by water in water-rich mixtures but is preferentially solvated by methanol in methanol-rich mixtures. © 2016 Elsevier Ltd. All rights reserved.0000-0002-4835-9739danielr.delgado@campusucc.edu.co264-276Academic PressACTIVITY COEFFICIENTSENTHALPYENTHALPY-ENTROPY RELATIONSHIPENTROPYGIBBS FREE ENERGYJOUYBAN-ACREE MODELKIRKWOOD-BUFF INTEGRALSMETHANOLMIXINGMIXTURESORGANIC SOLVENTSPREFERENTIAL SOLVATIONSOLUBILITYSOLUTION THERMODYNAMICSSOLVATIONSULFAMETHAZINESULFUR COMPOUNDSTHERMODYNAMIC FUNCTIONSTHERMODYNAMIC QUANTITIESTHERMODYNAMICSSolution thermodynamics and preferential solvation of sulfamethazine in (methanol + water) mixturesArtículohttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionJ CHEM THERMODYNinfo:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Publication20.500.12494/49561oai:repository.ucc.edu.co:20.500.12494/495612024-08-20 16:20:29.728metadata.onlyhttps://repository.ucc.edu.coRepositorio Institucional Universidad Cooperativa de Colombiabdigital@metabiblioteca.com |
dc.title.spa.fl_str_mv |
Solution thermodynamics and preferential solvation of sulfamethazine in (methanol + water) mixtures |
title |
Solution thermodynamics and preferential solvation of sulfamethazine in (methanol + water) mixtures |
spellingShingle |
Solution thermodynamics and preferential solvation of sulfamethazine in (methanol + water) mixtures ACTIVITY COEFFICIENTS ENTHALPY ENTHALPY-ENTROPY RELATIONSHIP ENTROPY GIBBS FREE ENERGY JOUYBAN-ACREE MODEL KIRKWOOD-BUFF INTEGRALS METHANOL MIXING MIXTURES ORGANIC SOLVENTS PREFERENTIAL SOLVATION SOLUBILITY SOLUTION THERMODYNAMICS SOLVATION SULFAMETHAZINE SULFUR COMPOUNDS THERMODYNAMIC FUNCTIONS THERMODYNAMIC QUANTITIES THERMODYNAMICS |
title_short |
Solution thermodynamics and preferential solvation of sulfamethazine in (methanol + water) mixtures |
title_full |
Solution thermodynamics and preferential solvation of sulfamethazine in (methanol + water) mixtures |
title_fullStr |
Solution thermodynamics and preferential solvation of sulfamethazine in (methanol + water) mixtures |
title_full_unstemmed |
Solution thermodynamics and preferential solvation of sulfamethazine in (methanol + water) mixtures |
title_sort |
Solution thermodynamics and preferential solvation of sulfamethazine in (methanol + water) mixtures |
dc.creator.fl_str_mv |
Delgado, Daniel ricardo Almanza O.A. Martínez F. Peña M.A. Jouyban A. Acree W.E. Jr. |
dc.contributor.author.none.fl_str_mv |
Delgado, Daniel ricardo Almanza O.A. Martínez F. Peña M.A. Jouyban A. Acree W.E. Jr. |
dc.subject.spa.fl_str_mv |
ACTIVITY COEFFICIENTS ENTHALPY ENTHALPY-ENTROPY RELATIONSHIP ENTROPY GIBBS FREE ENERGY JOUYBAN-ACREE MODEL KIRKWOOD-BUFF INTEGRALS METHANOL MIXING MIXTURES ORGANIC SOLVENTS PREFERENTIAL SOLVATION SOLUBILITY SOLUTION THERMODYNAMICS SOLVATION SULFAMETHAZINE SULFUR COMPOUNDS THERMODYNAMIC FUNCTIONS THERMODYNAMIC QUANTITIES THERMODYNAMICS |
topic |
ACTIVITY COEFFICIENTS ENTHALPY ENTHALPY-ENTROPY RELATIONSHIP ENTROPY GIBBS FREE ENERGY JOUYBAN-ACREE MODEL KIRKWOOD-BUFF INTEGRALS METHANOL MIXING MIXTURES ORGANIC SOLVENTS PREFERENTIAL SOLVATION SOLUBILITY SOLUTION THERMODYNAMICS SOLVATION SULFAMETHAZINE SULFUR COMPOUNDS THERMODYNAMIC FUNCTIONS THERMODYNAMIC QUANTITIES THERMODYNAMICS |
description |
The solubility of sulfamethazine (SMT) in {methanol (1) + water (2)} co-solvent mixtures was determined at five different temperatures from (293.15 to 313.15) K. The sulfonamide exhibited its highest mole fraction solubility in pure methanol (d1 = 29.6 MPa1/2) and its lowest mole fraction solubility in water (d2 = 47.8 MPa1/2) at each of the five temperatures studied. The Jouyban-Acree model was used to correlate/predict the solubility values. The respective apparent thermodynamic functions Gibbs energy, enthalpy, and entropy of solution were obtained from the solubility data through the van't Hoff and Gibbs equations. Apparent thermodynamic quantities of mixing were also calculated for this drug using values of the ideal solubility reported in the literature. A non-linear enthalpy-entropy relationship was noted for SMT in plots of both the enthalpy vs. Gibbs energy of mixing and the enthalpy vs. entropy of mixing. These plots suggest two different trends according to the slopes obtained when the composition of the mixtures changes. Accordingly, the mechanism for SMT transfer processes in water-rich mixtures from water to the mixture with 0.70 in mass fraction of methanol is entropy driven. Conversely, the mechanism is enthalpy driven in mixtures whenever the methanol composition exceeds 0.70 mol fraction. An inverse Kirkwood-Buff integral analysis of the preferential solvation of SMT indicated that the drug is preferentially solvated by water in water-rich mixtures but is preferentially solvated by methanol in methanol-rich mixtures. © 2016 Elsevier Ltd. All rights reserved. |
publishDate |
2023 |
dc.date.issued.none.fl_str_mv |
01/01/2016 |
dc.date.accessioned.none.fl_str_mv |
2023-05-24T16:21:31Z |
dc.date.available.none.fl_str_mv |
2023-05-24T16:21:31Z |
dc.type.none.fl_str_mv |
Artículo |
dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
dc.type.coar.none.fl_str_mv |
http://purl.org/coar/resource_type/c_6501 |
dc.type.coarversion.none.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
dc.type.driver.none.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.redcol.none.fl_str_mv |
http://purl.org/redcol/resource_type/ART |
dc.type.version.none.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
http://purl.org/coar/resource_type/c_6501 |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
https://doi.org/10.1016/j.jct.2016.02.002 https://www.scopus.com/inward/record.uri?eid=2-s2.0-84958568243&doi=10.1016%2fj.jct.2016.02.002&partnerID=40&md5=81f4b62178ba7fcb1f827db4f14a587b |
dc.identifier.issn.spa.fl_str_mv |
00219614 |
dc.identifier.uri.none.fl_str_mv |
https://hdl.handle.net/20.500.12494/49561 |
dc.identifier.bibliographicCitation.spa.fl_str_mv |
Delgado Daniel ricardo,Almanza O.A.,Martínez F.,Peña M.A.,Jouyban A.,Acree W.E.,Jr..Solution thermodynamics and preferential solvation of sulfamethazine in (methanol + water) mixtures.J CHEM THERMODYN. 2016. 97.:p. 264-276 |
url |
https://doi.org/10.1016/j.jct.2016.02.002 https://www.scopus.com/inward/record.uri?eid=2-s2.0-84958568243&doi=10.1016%2fj.jct.2016.02.002&partnerID=40&md5=81f4b62178ba7fcb1f827db4f14a587b https://hdl.handle.net/20.500.12494/49561 |
identifier_str_mv |
00219614 Delgado Daniel ricardo,Almanza O.A.,Martínez F.,Peña M.A.,Jouyban A.,Acree W.E.,Jr..Solution thermodynamics and preferential solvation of sulfamethazine in (methanol + water) mixtures.J CHEM THERMODYN. 2016. 97.:p. 264-276 |
dc.relation.ispartofjournal.spa.fl_str_mv |
J CHEM THERMODYN |
dc.rights.accessrights.none.fl_str_mv |
info:eu-repo/semantics/openAccess |
dc.rights.coar.none.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
http://purl.org/coar/access_right/c_abf2 |
dc.format.extent.spa.fl_str_mv |
264-276 |
dc.publisher.spa.fl_str_mv |
Academic Press |
institution |
Universidad Cooperativa de Colombia |
repository.name.fl_str_mv |
Repositorio Institucional Universidad Cooperativa de Colombia |
repository.mail.fl_str_mv |
bdigital@metabiblioteca.com |
_version_ |
1814247065218187264 |