Factores de riesgo para infección por Pseudomonas aeruginosa multi-resistente en un hospital de alta complejidad

Introduction: Multi-resistant Pseudomonas aeruginosa (MR) is frequently associated with healthcare infections. Its epidemiology is complex and few studies help to understand it. A study about risk factors associated with this type of bacteria is needed. Objective: To determine risk factors associated with MR P. aeruginosa infection in hospitalized patients from the Hospital Universitario San Vicente Foundation-Medellin. Materials and Methods: case-control study to identify risk factors associated with infection by MR P. aeruginosa. Results: 140 patients were included, 70 in each group. Bivariate analysis found association with previous use of carbapenems (OR 3.12 - IC 1.21 to 8.03, p = 0.02), aminoglycosides (OR 5.09 - CI: 1.38 to 18, 77, p = 0.01) and days of stay prior to isolation of the organism (OR 1.03 - CI: 1.01-1.05, p = 0.01). In multivariate analysis MR P. aeruginosa infection was associated with hospital stay (OR 1.03 - IC 1.01 to 1.05), use of aminoglycosides (OR 1.30 to 19.28) and treatment with two or more antimicrobials in the last 30 days (OR 3.09 - CI: 1.26 to 7.58). The risk of developing infection was 3% per day of hospital stay prior to isolation of the agent. Conclusion: Developing MR P. aeruginosa infection was associated with prior use of antimicrobials and prior hospital stay. © 2014, Sociedad Chilena de Infectologia. All rights reserved.

• Autores: Ossa Giraldo, Ana Claudia; Echeverri-Toro L.M.; Santos Z.M.; García M.G.; Agudelo Y.; Ramírez F.; Ospina S.
• Tipo de recurso: Article of journal
• Fecha de publicación: 2014
• Institución: Universidad Cooperativa de Colombia
• Repositorio: Repositorio UCC
• OAI Identifier: oai:repository.ucc.edu.co:20.500.12494/41267
• Acceso en línea: https://doi.org/10.4067/S0716-10182014000400003; https://www.scopus.com/inward/record.uri?eid=2-s2.0-85082739018&doi=10.3303%2fCET2079037&partnerID=40&md5=156899e95eafc30168736c0e5e9e1fb1; https://hdl.handle.net/20.500.12494/41267
• Palabra clave: adult; aged; case control study; Colombia; cross infection; female; human; length of stay; male; microbiology; middle aged; multidrug resistance; Pseudomonas aeruginosa; Pseudomonas Infections; risk factor; tertiary care center; Adult; Aged; Case-Control Studies; Colombia; Cross Infection; Drug Resistance; Multiple; Bacterial; Female; Humans; Length of Stay; Male; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Risk Factors; Tertiary Care Centers
• Rights: closedAccess
• License: http://purl.org/coar/access_right/c_14cb