Thermodynamic study of the solubility of ethylparaben in acetonitrile + water cosolvent mixtures at different temperatures
The thermodynamic analysis of the solubility of ethylparaben (1) in acetonitrile (1) + water (2) cosolvent mixtures at 9 temperatures, 10 cosolvent mixtures and the 2 pure solvents, water and acetonitrile, is reported herein. The solution thermodynamic functions were calculated from the experimental...
- Autores:
-
Romero Nieto, Alba Miledy
Cerquera, Néstor Enrique
Martínez, Fleming
Delgado, Daniel Ricardo
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2019
- Institución:
- Universidad Cooperativa de Colombia
- Repositorio:
- Repositorio UCC
- Idioma:
- OAI Identifier:
- oai:repository.ucc.edu.co:20.500.12494/15766
- Acceso en línea:
- https://doi.org/10.1016/j.molliq.2019.110894
https://hdl.handle.net/20.500.12494/15766
- Palabra clave:
- Thermodynamic analysis
Cosolvent mixture
Ethylparaben
Acetonitrile
Solubility
Thermodynamic analysis
Cosolvent mixture
Ethylparaben
Acetonitrile
Solubility
- Rights
- closedAccess
- License
- Atribución – No comercial – Sin Derivar
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Thermodynamic study of the solubility of ethylparaben in acetonitrile + water cosolvent mixtures at different temperatures |
| title |
Thermodynamic study of the solubility of ethylparaben in acetonitrile + water cosolvent mixtures at different temperatures |
| spellingShingle |
Thermodynamic study of the solubility of ethylparaben in acetonitrile + water cosolvent mixtures at different temperatures Thermodynamic analysis Cosolvent mixture Ethylparaben Acetonitrile Solubility Thermodynamic analysis Cosolvent mixture Ethylparaben Acetonitrile Solubility |
| title_short |
Thermodynamic study of the solubility of ethylparaben in acetonitrile + water cosolvent mixtures at different temperatures |
| title_full |
Thermodynamic study of the solubility of ethylparaben in acetonitrile + water cosolvent mixtures at different temperatures |
| title_fullStr |
Thermodynamic study of the solubility of ethylparaben in acetonitrile + water cosolvent mixtures at different temperatures |
| title_full_unstemmed |
Thermodynamic study of the solubility of ethylparaben in acetonitrile + water cosolvent mixtures at different temperatures |
| title_sort |
Thermodynamic study of the solubility of ethylparaben in acetonitrile + water cosolvent mixtures at different temperatures |
| dc.creator.fl_str_mv |
Romero Nieto, Alba Miledy Cerquera, Néstor Enrique Martínez, Fleming Delgado, Daniel Ricardo |
| dc.contributor.author.none.fl_str_mv |
Romero Nieto, Alba Miledy Cerquera, Néstor Enrique Martínez, Fleming Delgado, Daniel Ricardo |
| dc.subject.spa.fl_str_mv |
Thermodynamic analysis Cosolvent mixture Ethylparaben Acetonitrile Solubility |
| topic |
Thermodynamic analysis Cosolvent mixture Ethylparaben Acetonitrile Solubility Thermodynamic analysis Cosolvent mixture Ethylparaben Acetonitrile Solubility |
| dc.subject.other.spa.fl_str_mv |
Thermodynamic analysis Cosolvent mixture Ethylparaben Acetonitrile Solubility |
| description |
The thermodynamic analysis of the solubility of ethylparaben (1) in acetonitrile (1) + water (2) cosolvent mixtures at 9 temperatures, 10 cosolvent mixtures and the 2 pure solvents, water and acetonitrile, is reported herein. The solution thermodynamic functions were calculated from the experimental solubility data, using the van't Hoff and Gibbs equations, following the approach proposed by Krug et al. Thus, the solubility of ethylparaben is thermo-dependent, reaching its minimum value in pure water at 278.15 K and its maximum value in the cosolvent mixture w1 = 0.90 at 318.18 K. The enthalpy of solution is positive in all cases, which is an indication of the endothermic process, with an enthalpy-driven mixing process in mixtures rich in water and by entropy mixtures rich in acetonitrile. |
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2019 |
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2019-12-16T22:57:43Z |
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2019-12-16T22:57:43Z |
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2019-08-01 |
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Artículo |
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https://hdl.handle.net/20.500.12494/15766 |
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Alba Miledy Romero-Nieto, Nestor Enrique Cerquera, Fleming Martínez, Daniel Ricardo Delgado, Thermodynamic study of the solubility of ethylparaben in acetonitrile+ water cosolvent mixtures at different temperatures, Journal of Molecular Liquids Volume 287, 1 August 2019, 110894 |
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Alba Miledy Romero-Nieto, Nestor Enrique Cerquera, Fleming Martínez, Daniel Ricardo Delgado, Thermodynamic study of the solubility of ethylparaben in acetonitrile+ water cosolvent mixtures at different temperatures, Journal of Molecular Liquids Volume 287, 1 August 2019, 110894 |
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https://www.sciencedirect.com/science/article/abs/pii/S0167732219313078 |
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Journal of Molecular Liquids |
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J.F. Gomes, A. Lopes, M. Gmureka, R.M. Quinta-Ferreira, R.C. Martins Study of the influence of the matrix characteristics over the photocatalytic ozonation of parabens using Ag-TiO2 Sci. Total Environ., 646 (2019), pp. 1468-1477 T. Benijts, W. Lambert, A. Leenheer Analysis of multiple endocrine disruptors in environmental waters via wide-spectrum solid-phase extraction and dual-polarity ionization LC-Ion Trap-MS/MS Anal. Chem., 76 (2004), pp. 704-711 E.J. Routledge, J. Parker, J. Odum, J. Ashby, J.P. Sumpter Some alkyl hydroxy benzoate preservatives (parabens) are estrogenic Toxicol. Appl. Pharmacol., 153 (1998), pp. 12-19 P.D. Darbre, A. Aljarrah, W.R. Miller, N.G. Coldham, M.J. Sauer, G.S. Pope Concentrations of parabens in human breast tumours J. Appl. Toxicol., 24 (2004), pp. 5-13 A. Jouyban Handbook of Solubility Data for Pharmaceuticals CRC Press, Boca Raton, FL (2010) A.N. Martin, P. Bustamante, A.H.C. Chun Physical Pharmacy: Physical Chemical Principles in the Pharmaceutical Sciences (4th ed.), Lea & Febiger, Philadelphia (1993) J.K.H. Ma, B.W. Hadzija Basic Physical Pharmacy Jones & Bartlett Learning, Burlington (2013) D. Bledzka, J. Gromadzińska, W. Wasowicz Parabens. From environmental studies to human health Environ. Int., 67 (2014), pp. 27-42 D.I. Caviedes Rubio, D.R. Delgado Regulación ambiental sobre los productos farmacéuticos residuales en ambientes acuáticos Entornos, 28 (2015), pp. 76-80 D.I. Caviedes Rubio, D.M. Camacho Feria, D.R. Delgado Tratamientos para la remoción de antibacteriales y agentes antimicrobiales presentes en aguas residuales Rev. Logos Cienc. Tecnol., 9 (2017), pp. 43-62 Z.J. Cárdenas, D.M. Jiménez, D.R. Delgado, O.A. Almanza, A. Jouyban, F. Martínez, W.E. Acree Jr. Solubility and preferential solvation of some n-alkyl-parabens in methanol + water mixtures at 298.15 K J. Chem. Thermodyn., 108 (2017), pp. 26-37 T. Higuchi, K.A. Connors Phase-solubility techniques Advances in Analytical Chemistry and Instrumentation, vol. 4, John Wiley & Sons, Inc, New York (1965) D.M. Jiménez, Z.J. Cárdenas, D.R. Delgado, M.Á. Peña, F. Martínez Solubility temperature dependence and preferential solvation of sulfadiazine in 1, 4-dioxane+ water co-solvent mixtures Fluid Phase Equilib., 397 (2015), pp. 26-36 D.R. Delgado, E.F. Vargas, F. Martínez Thermodynamic study of the solubility of procaine HCl in some ethanol+ water cosolvent mixtures J. Chem. Eng. Data, 55 (2010), pp. 2900-2904 A.J. Parker The effects of solvation on the properties of anions in dipolar aprotic solvents Q. Rev. Chem. Soc. (2) (1962), pp. 163-187 A.N. Paruta, B.B. Sheth Solubility of parabens in syrup vehicles J. Pharm. Sci., 55 (1966), pp. 1208-1211 A.E. Beezer, S. Forster, W.-B. Park, G.J. Rimmer, G. Buckton Solution thermodynamics of 4-hydroxybenzoates in water, 95% ethanol-water, 1-octanol and hexane Thermochim. Acta, 178 (1991), pp. 59-65 A.F.M. Barton Solubility parameter Chem. Rev., 75 (1975), pp. 731-753 S.H. Yalkowsky Solubility and Solubilization in Aqueous Media American Chemical Society and Oxford University Press, New York (1999) A.N. Paruta, B.J. Sciarrone, N.G. Lordi Solubility of salicylic acid as a function of dielectric constant J. Pharm. Sci., 53 (1964), pp. 1349-1353 A.N. Paruta, B.J. Sciarrone, N.G. Lordi Solubility profiles for the xanthines in dioxane-water mixtures J. Pharm. Sci., 54 (1965), pp. 838-841 A.N. Paruta Solubility of the parabens in dioxane-water mixtures J. Pharm. Sci., 58 (1969), pp. 204-206 M.A. Peña, P. Bustamante, B. Escalera, A. Reíllo, J.M. Bosque-Sendra Solubility and phase separation of benzocaine and salicylic acid in 1,4-dioxane–water mixtures at several temperatures J. Pharm. Biomed. Anal., 36 (2004), pp. 571-578 J.H. Hildebrand The term “regular solution” Nature, 168 (1951), p. 868 J.H. Hildebrand, J.M. Prausnitz, R.L. Scott Regular and Related Solutions Van Nostrand Reinhold, New York (1970) G.L. Perlovich, S.V. Rodionov, A. Bauer-Brandl Thermodynamics of solubility, sublimation and solvation processes of parabens Eur. J. Pharm. Sci., 24 (2005), pp. 25-33 R.J. Prankerd Solid-state properties of drugs. I. Estimation of heat capacities for fusion and thermodynamic functions for solution from aqueous solubility-temperature dependence measurements Int. J. Pharm., 84 (1992), pp. 233-244 |
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Romero Nieto, Alba MiledyCerquera, Néstor EnriqueMartínez, FlemingDelgado, Daniel RicardoVol. 2872019-12-16T22:57:43Z2019-12-16T22:57:43Z2019-08-01https://doi.org/10.1016/j.molliq.2019.110894https://hdl.handle.net/20.500.12494/15766Alba Miledy Romero-Nieto, Nestor Enrique Cerquera, Fleming Martínez, Daniel Ricardo Delgado, Thermodynamic study of the solubility of ethylparaben in acetonitrile+ water cosolvent mixtures at different temperatures, Journal of Molecular Liquids Volume 287, 1 August 2019, 110894The thermodynamic analysis of the solubility of ethylparaben (1) in acetonitrile (1) + water (2) cosolvent mixtures at 9 temperatures, 10 cosolvent mixtures and the 2 pure solvents, water and acetonitrile, is reported herein. The solution thermodynamic functions were calculated from the experimental solubility data, using the van't Hoff and Gibbs equations, following the approach proposed by Krug et al. Thus, the solubility of ethylparaben is thermo-dependent, reaching its minimum value in pure water at 278.15 K and its maximum value in the cosolvent mixture w1 = 0.90 at 318.18 K. The enthalpy of solution is positive in all cases, which is an indication of the endothermic process, with an enthalpy-driven mixing process in mixtures rich in water and by entropy mixtures rich in acetonitrile.The thermodynamic analysis of the solubility of ethylparaben (1) in acetonitrile (1) + water (2) cosolvent mixtures at 9 temperatures, 10 cosolvent mixtures and the 2 pure solvents, water and acetonitrile, is reported herein. The solution thermodynamic functions were calculated from the experimental solubility data, using the van't Hoff and Gibbs equations, following the approach proposed by Krug et al. Thus, the solubility of ethylparaben is thermo-dependent, reaching its minimum value in pure water at 278.15 K and its maximum value in the cosolvent mixture w1 = 0.90 at 318.18 K. The enthalpy of solution is positive in all cases, which is an indication of the endothermic process, with an enthalpy-driven mixing process in mixtures rich in water and by entropy mixtures rich in acetonitrile.Highlights. -- Abstract. -- Keywords. -- 1. Introduction. -- 2. Experimental. -- 2.1. Reagents. -- 2.2. Preparation of the solvent mixture. -- 2.3. Determination of solubility. -- 3. Results and discussion. -- 3.1. Solubility of ethyl paraben in cosolvent mixtures of acetonitrile + water. -- 3.2. Activity coefficients of ethylparaben. -- 3.3. Thermodynamic functions of solution. -- 3.4. Thermodynamic functions of ethylparaben transfer. -- 3.5. Thermodynamic functions of the ethylparaben mixture. -- 3.6. Enthalpy–entropy compensation. -- 4. Conclusions. -- Acknowledgements. -- Declaration of competing interest. -- References.http://scienti.colciencias.gov.co:8081/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0001402116https://orcid.org/0000-0002-4835-9739https://scienti.colciencias.gov.co/gruplac/jsp/visualiza/visualizagr.jsp?nro=00000000004151danielr.delgado@campusucc.edu.cohttps://scholar.google.com/citations?hl=es&user=OW0mejcAAAAJ&view_op=list_works10El sevierUniversidad Cooperativa de Colombia, Facultad de Ingenierías, Ingeniería Industrial, NeivaIngeniería IndustrialNeivahttps://www.sciencedirect.com/science/article/abs/pii/S0167732219313078Journal of Molecular LiquidsJ.F. Gomes, A. Lopes, M. Gmureka, R.M. Quinta-Ferreira, R.C. Martins Study of the influence of the matrix characteristics over the photocatalytic ozonation of parabens using Ag-TiO2 Sci. Total Environ., 646 (2019), pp. 1468-1477T. Benijts, W. Lambert, A. Leenheer Analysis of multiple endocrine disruptors in environmental waters via wide-spectrum solid-phase extraction and dual-polarity ionization LC-Ion Trap-MS/MS Anal. Chem., 76 (2004), pp. 704-711E.J. Routledge, J. Parker, J. Odum, J. Ashby, J.P. Sumpter Some alkyl hydroxy benzoate preservatives (parabens) are estrogenic Toxicol. Appl. Pharmacol., 153 (1998), pp. 12-19P.D. Darbre, A. Aljarrah, W.R. Miller, N.G. Coldham, M.J. Sauer, G.S. Pope Concentrations of parabens in human breast tumours J. Appl. Toxicol., 24 (2004), pp. 5-13A. Jouyban Handbook of Solubility Data for Pharmaceuticals CRC Press, Boca Raton, FL (2010)A.N. Martin, P. Bustamante, A.H.C. Chun Physical Pharmacy: Physical Chemical Principles in the Pharmaceutical Sciences (4th ed.), Lea & Febiger, Philadelphia (1993)J.K.H. Ma, B.W. Hadzija Basic Physical Pharmacy Jones & Bartlett Learning, Burlington (2013)D. Bledzka, J. Gromadzińska, W. Wasowicz Parabens. From environmental studies to human health Environ. Int., 67 (2014), pp. 27-42D.I. Caviedes Rubio, D.R. Delgado Regulación ambiental sobre los productos farmacéuticos residuales en ambientes acuáticos Entornos, 28 (2015), pp. 76-80D.I. Caviedes Rubio, D.M. Camacho Feria, D.R. Delgado Tratamientos para la remoción de antibacteriales y agentes antimicrobiales presentes en aguas residuales Rev. Logos Cienc. Tecnol., 9 (2017), pp. 43-62Z.J. Cárdenas, D.M. Jiménez, D.R. Delgado, O.A. Almanza, A. Jouyban, F. Martínez, W.E. Acree Jr. Solubility and preferential solvation of some n-alkyl-parabens in methanol + water mixtures at 298.15 K J. Chem. Thermodyn., 108 (2017), pp. 26-37T. Higuchi, K.A. Connors Phase-solubility techniques Advances in Analytical Chemistry and Instrumentation, vol. 4, John Wiley & Sons, Inc, New York (1965)D.M. Jiménez, Z.J. Cárdenas, D.R. Delgado, M.Á. Peña, F. Martínez Solubility temperature dependence and preferential solvation of sulfadiazine in 1, 4-dioxane+ water co-solvent mixtures Fluid Phase Equilib., 397 (2015), pp. 26-36D.R. Delgado, E.F. Vargas, F. Martínez Thermodynamic study of the solubility of procaine HCl in some ethanol+ water cosolvent mixtures J. Chem. Eng. Data, 55 (2010), pp. 2900-2904A.J. Parker The effects of solvation on the properties of anions in dipolar aprotic solvents Q. Rev. Chem. Soc. (2) (1962), pp. 163-187A.N. Paruta, B.B. Sheth Solubility of parabens in syrup vehicles J. Pharm. Sci., 55 (1966), pp. 1208-1211A.E. Beezer, S. Forster, W.-B. Park, G.J. Rimmer, G. Buckton Solution thermodynamics of 4-hydroxybenzoates in water, 95% ethanol-water, 1-octanol and hexane Thermochim. Acta, 178 (1991), pp. 59-65A.F.M. Barton Solubility parameter Chem. Rev., 75 (1975), pp. 731-753S.H. Yalkowsky Solubility and Solubilization in Aqueous Media American Chemical Society and Oxford University Press, New York (1999)A.N. Paruta, B.J. Sciarrone, N.G. Lordi Solubility of salicylic acid as a function of dielectric constant J. Pharm. Sci., 53 (1964), pp. 1349-1353A.N. Paruta, B.J. Sciarrone, N.G. Lordi Solubility profiles for the xanthines in dioxane-water mixtures J. Pharm. Sci., 54 (1965), pp. 838-841A.N. Paruta Solubility of the parabens in dioxane-water mixtures J. Pharm. Sci., 58 (1969), pp. 204-206M.A. Peña, P. Bustamante, B. Escalera, A. Reíllo, J.M. Bosque-Sendra Solubility and phase separation of benzocaine and salicylic acid in 1,4-dioxane–water mixtures at several temperatures J. Pharm. Biomed. Anal., 36 (2004), pp. 571-578J.H. Hildebrand The term “regular solution” Nature, 168 (1951), p. 868J.H. Hildebrand, J.M. Prausnitz, R.L. Scott Regular and Related Solutions Van Nostrand Reinhold, New York (1970)G.L. Perlovich, S.V. Rodionov, A. Bauer-Brandl Thermodynamics of solubility, sublimation and solvation processes of parabens Eur. J. Pharm. Sci., 24 (2005), pp. 25-33R.J. Prankerd Solid-state properties of drugs. I. Estimation of heat capacities for fusion and thermodynamic functions for solution from aqueous solubility-temperature dependence measurements Int. J. Pharm., 84 (1992), pp. 233-244Thermodynamic analysisCosolvent mixtureEthylparabenAcetonitrileSolubilityThermodynamic analysisCosolvent mixtureEthylparabenAcetonitrileSolubilityThermodynamic study of the solubility of ethylparaben in acetonitrile + water cosolvent mixtures at different temperaturesArtículohttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAtribución – No comercial – Sin Derivarinfo:eu-repo/semantics/closedAccesshttp://purl.org/coar/access_right/c_14cbPublicationLICENSElicense.txtlicense.txttext/plain; charset=utf-84334https://repository.ucc.edu.co/bitstreams/2d68f2d2-f495-460c-90f0-aaccf65965d6/download3bce4f7ab09dfc588f126e1e36e98a45MD52ORIGINALThermodynamic study of the solubility of ethylparaben in acetonitrile + water cosolvent mixtures at different temperatures.pdfThermodynamic study of the solubility of ethylparaben in acetonitrile + water cosolvent mixtures at different temperatures.pdfArtículo Científicoapplication/pdf1432612https://repository.ucc.edu.co/bitstreams/ce905ab1-510c-432c-9292-a8a43619076a/downloadb17dd01bc7f9c9ccc6027f71447125b5MD51TEXTThermodynamic study of the solubility of ethylparaben in acetonitrile + water cosolvent mixtures at different temperatures.pdf.txtThermodynamic study of the solubility of ethylparaben in acetonitrile + water cosolvent mixtures at different temperatures.pdf.txtExtracted texttext/plain43750https://repository.ucc.edu.co/bitstreams/7030e4fc-fb33-4129-89d8-97b51bb57a96/download122095b9ade4eeea8c8ebc3f4882e655MD53THUMBNAILThermodynamic study of the solubility of ethylparaben in acetonitrile + water cosolvent mixtures at different temperatures.pdf.jpgThermodynamic study of the solubility of ethylparaben in acetonitrile + water cosolvent mixtures at different temperatures.pdf.jpgGenerated 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