Phylogenetic evidence of the intercontinental circulation of a Canine distemper virus lineage in the Americas
Canine distemper virus (CDV) is the cause of a multisystem disease in domestic dogs and wild animals, infecting more than 20 carnivore and non-carnivore families and even infecting human cell lines in in vitro conditions. Phylogenetic classification based on the hemagglutinin gene shows 17 lineages...
- Autores:
-
Ruiz Sáenz, Julián
Duque Valencia, July
Forero Muñoz, Norma
Díaz, Francisco Javier
Martins, Elisabete
Barato, Paola
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2019
- Institución:
- Universidad Cooperativa de Colombia
- Repositorio:
- Repositorio UCC
- Idioma:
- OAI Identifier:
- oai:repository.ucc.edu.co:20.500.12494/15185
- Acceso en línea:
- https://hdl.handle.net/20.500.12494/15185
- Palabra clave:
- Viral epidemiology
Viral evolution
virus
disease
- Rights
- openAccess
- License
- Atribución
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Phylogenetic evidence of the intercontinental circulation of a Canine distemper virus lineage in the Americas |
| title |
Phylogenetic evidence of the intercontinental circulation of a Canine distemper virus lineage in the Americas |
| spellingShingle |
Phylogenetic evidence of the intercontinental circulation of a Canine distemper virus lineage in the Americas Viral epidemiology Viral evolution virus disease |
| title_short |
Phylogenetic evidence of the intercontinental circulation of a Canine distemper virus lineage in the Americas |
| title_full |
Phylogenetic evidence of the intercontinental circulation of a Canine distemper virus lineage in the Americas |
| title_fullStr |
Phylogenetic evidence of the intercontinental circulation of a Canine distemper virus lineage in the Americas |
| title_full_unstemmed |
Phylogenetic evidence of the intercontinental circulation of a Canine distemper virus lineage in the Americas |
| title_sort |
Phylogenetic evidence of the intercontinental circulation of a Canine distemper virus lineage in the Americas |
| dc.creator.fl_str_mv |
Ruiz Sáenz, Julián Duque Valencia, July Forero Muñoz, Norma Díaz, Francisco Javier Martins, Elisabete Barato, Paola |
| dc.contributor.author.none.fl_str_mv |
Ruiz Sáenz, Julián Duque Valencia, July Forero Muñoz, Norma Díaz, Francisco Javier Martins, Elisabete Barato, Paola |
| dc.subject.spa.fl_str_mv |
Viral epidemiology Viral evolution virus disease |
| topic |
Viral epidemiology Viral evolution virus disease |
| description |
Canine distemper virus (CDV) is the cause of a multisystem disease in domestic dogs and wild animals, infecting more than 20 carnivore and non-carnivore families and even infecting human cell lines in in vitro conditions. Phylogenetic classification based on the hemagglutinin gene shows 17 lineages with a phylogeographic distribution pattern. In Medellín (Colombia), the lineage South America-3 is considered endemic. Phylogenetic studies conducted in Ecuador using fragment coding for the fusion protein signal peptide (Fsp) characterized a new strain belonging to a different lineage. For understanding the distribution of the South America-3 lineage in the north of the South American continent, we characterized CDV from three Colombian cities (Medellín, Bucaramanga, and Bogotá). Using phylogenetic analysis of the hemagglutinin gene and the Fsp region, we confirmed the circulation of CDV South America-3 in different areas of Colombia. We also described, for the first time to our knowledge, the circulation of a new lineage in Medellín that presents a group monophyletic with strains previously characterized in dogs in Ecuador and in wildlife and domestic dogs in the United States, for which we propose the name “South America/North America-4” due its intercontinental distribution. In conclusion, our results indicated that there are at least four different CDV lineages circulating in domestic dogs in South America: the Europe/South America-1 lineage circulating in Brazil, Uruguay, and Argentina; the South America-2 lineage restricted to Argentina; the South America-3 lineage, which has only been reported in Colombia; and lastly an intercontinental lineage present in Colombia, Ecuador, and the United States, referred to here as the “South America/North America-4” lineage. |
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2019 |
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2019-11-22T14:58:13Z |
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2019-11-22T14:58:13Z |
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2019-10-31 |
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Artículo |
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Duque Valencia, J., Forero Muñoz, N. R., Díaz, F.J., Martins, E., Barato, P. y Ruiz Saenz, J. (2019) Phylogenetic evidence of the intercontinental circulation of a Canine distemper virus lineage in the Americas. Sci Rep. 2019 Oct 31;9(1):15747. doi: 10.1038/s41598-019-52345-9. |
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1. de Vries, R. D., Duprex, W. P. & de Swart, R. L. Morbillivirus infections: an introduction. Viruses 7, 699–706, https://doi.org/10.3390/v7020699 (2015). 2. Beineke, A., Baumgartner, W. & Wohlsein, P. Cross-species transmission of canine distemper virus-an update. One Health 1, 49–59, https://doi.org/10.1016/j.onehlt.2015.09.002 (2015). 3. Martinez-Gutierrez, M. & Ruiz-Saenz, J. Diversity of susceptible hosts in canine distemper virus infection: a systematic review and data synthesis. BMC Vet Res 12, 78, https://doi.org/10.1186/s12917-016-0702-z (2016). 4. McCarthy, A. J., Shaw, M. A. & Goodman, S. J. Pathogen evolution and disease emergence in carnivores. Proc Biol Sci 274, 3165–3174, https://doi.org/10.1098/rspb.2007.0884 (2007). 5. da Fontoura Budaszewski, R. & von Messling, V. Morbillivirus Experimental Animal Models: Measles Virus Pathogenesis Insights from Canine Distemper Virus. Viruses 8, https://doi.org/10.3390/v8100274 (2016). 6. Loots, A. K., Mitchell, E., Dalton, D. L., Kotze, A. & Venter, E. H. Advances in canine distemper virus pathogenesis research: a wildlife perspective. J Gen Virol 98, 311–321, https://doi.org/10.1099/jgv.0.000666 (2017). 7. Deem, S. L., Spelman, L. H., Yates, R. A. & Montali, R. J. Canine distemper in terrestrial carnivores: a review. J Zoo Wildl Med 31, 441–451, https://doi.org/10.1638/1042-7260(2000)031[0441:CDITCA]2.0.CO;2 (2000). 8. Sawatsky, B. & von Messling, V. Canine distemper viruses expressing a hemagglutinin without N-glycans lose virulence but retain immunosuppression. J Virol 84, 2753–2761, https://doi.org/10.1128/JVI.01813-09 (2010). 9. Iwatsuki, K. et al. Antigenic differences in the H proteins of canine distemper viruses. Vet Microbiol 71, 281–286 (2000). 10. Sarute, N. et al. The fusion protein signal-peptide-coding region of canine distemper virus: a useful tool for phylogenetic reconstruction and lineage identification. PLoS One 8, e63595, https://doi.org/10.1371/journal.pone.0063595 (2013). 11. Sarute, N. et al. Molecular typing of canine distemper virus strains reveals the presence of a new genetic variant in South America. Virus Genes 48, 474–478, https://doi.org/10.1007/s11262-014-1054-z (2014). 12. Romanutti, C., Gallo Calderon, M., Keller, L., Mattion, N. & La Torre, J. RT-PCR and sequence analysis of the full-length fusion protein of Canine Distemper Virus from domestic dogs. J Virol Methods 228, 79–83, https://doi.org/10.1016/j.jviromet.2015.11.011 (2016). 13. Panzera, Y., Sarute, N., Carrau, L., Aldaz, J. & Perez, R. Genetic diversity of canine distemper virus in South America. Br J Virol 1, 48 (2014). 14. Freitas, L. A., Leme, R. A., Saporiti, V., Alfieri, A. A. & Alfieri, A. F. Molecular analysis of the full-length F gene of Brazilian strains of canine distemper virus shows lineage co-circulation and variability between field and vaccine strains. Virus Res 264, 8–15, https://doi.org/10.1016/j.virusres.2019.02.009 (2019). 15. Anis, E., Newell, T. K., Dyer, N. & Wilkes, R. P. Phylogenetic analysis of the wild-type strains of canine distemper virus circulating in the United States. Virol J 15, 118, https://doi.org/10.1186/s12985-018-1027-2 (2018). 16. Blixenkrone-Møller, M. et al. Antigenic relationships between field isolates of morbilliviruses from different carnivores. Arch Virol 123, 279–294 (1992). 17. Espinal, M. A., Diaz, F. J. & Ruiz-Saenz, J. Phylogenetic evidence of a new canine distemper virus lineage among domestic dogs in Colombia, South America. Vet Microbiol 172, 168–176, https://doi.org/10.1016/j.vetmic.2014.05.019 (2014). 18. Haas, L. et al. Analysis of the haemagglutinin gene of current wild-type canine distemper virus isolates from Germany. Virus Res 48, 165–171 (1997). 19. Harder, T. C. et al. Canine distemper virus from diseased large felids: biological properties and phylogenetic relationships. J Gen Virol 77(Pt 3), 397–405, https://doi.org/10.1099/0022-1317-77-3-397 (1996). 20. Panzera, Y. et al. Evidence of two co-circulating genetic lineages of canine distemper virus in South America. Virus Res 163, 401–404, https://doi.org/10.1016/j.virusres.2011.10.008 (2012). 21. Riley, M. C. & Wilkes, R. P. Sequencing of emerging canine distemper virus strain reveals new distinct genetic lineage in the United States associated with disease in wildlife and domestic canine populations. Virol J 12, 219, https://doi.org/10.1186/s12985-015-0445-7 (2015). 22. Nikolin, V. M. et al. Canine distemper virus in the Serengeti ecosystem: molecular adaptation to different carnivore species. Mol Ecol 26, 2111–2130, https://doi.org/10.1111/mec.13902 (2017). Zhao, J. J. et al. Phylogenetic analysis of the haemagglutinin gene of canine distemper virus strains detected from breeding foxes, raccoon dogs and minks in China. Vet Microbiol 140, 34–42, https://doi.org/10.1016/j.vetmic.2009.07.010 (2010). |
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Ruiz Sáenz, JuliánDuque Valencia, JulyForero Muñoz, NormaDíaz, Francisco Javier Martins, ElisabeteBarato, Paola9(1)2019-11-22T14:58:13Z2019-11-22T14:58:13Z2019-10-312045-2322doi: 10.1038/s41598-019-52345-9.https://hdl.handle.net/20.500.12494/15185Duque Valencia, J., Forero Muñoz, N. R., Díaz, F.J., Martins, E., Barato, P. y Ruiz Saenz, J. (2019) Phylogenetic evidence of the intercontinental circulation of a Canine distemper virus lineage in the Americas. Sci Rep. 2019 Oct 31;9(1):15747. doi: 10.1038/s41598-019-52345-9.Canine distemper virus (CDV) is the cause of a multisystem disease in domestic dogs and wild animals, infecting more than 20 carnivore and non-carnivore families and even infecting human cell lines in in vitro conditions. Phylogenetic classification based on the hemagglutinin gene shows 17 lineages with a phylogeographic distribution pattern. In Medellín (Colombia), the lineage South America-3 is considered endemic. Phylogenetic studies conducted in Ecuador using fragment coding for the fusion protein signal peptide (Fsp) characterized a new strain belonging to a different lineage. For understanding the distribution of the South America-3 lineage in the north of the South American continent, we characterized CDV from three Colombian cities (Medellín, Bucaramanga, and Bogotá). Using phylogenetic analysis of the hemagglutinin gene and the Fsp region, we confirmed the circulation of CDV South America-3 in different areas of Colombia. We also described, for the first time to our knowledge, the circulation of a new lineage in Medellín that presents a group monophyletic with strains previously characterized in dogs in Ecuador and in wildlife and domestic dogs in the United States, for which we propose the name “South America/North America-4” due its intercontinental distribution. In conclusion, our results indicated that there are at least four different CDV lineages circulating in domestic dogs in South America: the Europe/South America-1 lineage circulating in Brazil, Uruguay, and Argentina; the South America-2 lineage restricted to Argentina; the South America-3 lineage, which has only been reported in Colombia; and lastly an intercontinental lineage present in Colombia, Ecuador, and the United States, referred to here as the “South America/North America-4” lineage.http://scienti.colciencias.gov.co:8081/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0000153095https://orcid.org/0000-0002-1447-1458julian.ruizs@campusucc.edu.cohttps://scholar.google.com/citations?user=o3Y7mZwAAAAJ&hl=esUniversidad Cooperativa de Colombia, Facultad de Ciencias de la Salud, Medicina Veterinaría y Zootecnia, BucaramangaNatureMedicina veterinaria y zootecniaBucaramangahttps://www.nature.com/articles/s41598-019-52345-9Scientific reports.1. de Vries, R. D., Duprex, W. P. & de Swart, R. L. Morbillivirus infections: an introduction. Viruses 7, 699–706, https://doi.org/10.3390/v7020699 (2015).2. Beineke, A., Baumgartner, W. & Wohlsein, P. Cross-species transmission of canine distemper virus-an update. One Health 1, 49–59, https://doi.org/10.1016/j.onehlt.2015.09.002 (2015).3. Martinez-Gutierrez, M. & Ruiz-Saenz, J. Diversity of susceptible hosts in canine distemper virus infection: a systematic review and data synthesis. BMC Vet Res 12, 78, https://doi.org/10.1186/s12917-016-0702-z (2016).4. McCarthy, A. J., Shaw, M. A. & Goodman, S. J. Pathogen evolution and disease emergence in carnivores. Proc Biol Sci 274, 3165–3174, https://doi.org/10.1098/rspb.2007.0884 (2007).5. da Fontoura Budaszewski, R. & von Messling, V. Morbillivirus Experimental Animal Models: Measles Virus Pathogenesis Insights from Canine Distemper Virus. Viruses 8, https://doi.org/10.3390/v8100274 (2016).6. Loots, A. K., Mitchell, E., Dalton, D. L., Kotze, A. & Venter, E. H. Advances in canine distemper virus pathogenesis research: a wildlife perspective. J Gen Virol 98, 311–321, https://doi.org/10.1099/jgv.0.000666 (2017).7. Deem, S. L., Spelman, L. H., Yates, R. A. & Montali, R. J. Canine distemper in terrestrial carnivores: a review. J Zoo Wildl Med 31, 441–451, https://doi.org/10.1638/1042-7260(2000)031[0441:CDITCA]2.0.CO;2 (2000).8. Sawatsky, B. & von Messling, V. Canine distemper viruses expressing a hemagglutinin without N-glycans lose virulence but retain immunosuppression. J Virol 84, 2753–2761, https://doi.org/10.1128/JVI.01813-09 (2010).9. Iwatsuki, K. et al. Antigenic differences in the H proteins of canine distemper viruses. Vet Microbiol 71, 281–286 (2000).10. Sarute, N. et al. The fusion protein signal-peptide-coding region of canine distemper virus: a useful tool for phylogenetic reconstruction and lineage identification. PLoS One 8, e63595, https://doi.org/10.1371/journal.pone.0063595 (2013).11. Sarute, N. et al. Molecular typing of canine distemper virus strains reveals the presence of a new genetic variant in South America. Virus Genes 48, 474–478, https://doi.org/10.1007/s11262-014-1054-z (2014).12. Romanutti, C., Gallo Calderon, M., Keller, L., Mattion, N. & La Torre, J. RT-PCR and sequence analysis of the full-length fusion protein of Canine Distemper Virus from domestic dogs. J Virol Methods 228, 79–83, https://doi.org/10.1016/j.jviromet.2015.11.011 (2016).13. Panzera, Y., Sarute, N., Carrau, L., Aldaz, J. & Perez, R. Genetic diversity of canine distemper virus in South America. Br J Virol 1, 48 (2014).14. Freitas, L. A., Leme, R. A., Saporiti, V., Alfieri, A. A. & Alfieri, A. F. Molecular analysis of the full-length F gene of Brazilian strains of canine distemper virus shows lineage co-circulation and variability between field and vaccine strains. Virus Res 264, 8–15, https://doi.org/10.1016/j.virusres.2019.02.009 (2019).15. Anis, E., Newell, T. K., Dyer, N. & Wilkes, R. P. Phylogenetic analysis of the wild-type strains of canine distemper virus circulating in the United States. Virol J 15, 118, https://doi.org/10.1186/s12985-018-1027-2 (2018).16. Blixenkrone-Møller, M. et al. Antigenic relationships between field isolates of morbilliviruses from different carnivores. Arch Virol 123, 279–294 (1992).17. Espinal, M. A., Diaz, F. J. & Ruiz-Saenz, J. Phylogenetic evidence of a new canine distemper virus lineage among domestic dogs in Colombia, South America. Vet Microbiol 172, 168–176, https://doi.org/10.1016/j.vetmic.2014.05.019 (2014).18. Haas, L. et al. Analysis of the haemagglutinin gene of current wild-type canine distemper virus isolates from Germany. Virus Res 48, 165–171 (1997).19. Harder, T. C. et al. Canine distemper virus from diseased large felids: biological properties and phylogenetic relationships. J Gen Virol 77(Pt 3), 397–405, https://doi.org/10.1099/0022-1317-77-3-397 (1996).20. Panzera, Y. et al. Evidence of two co-circulating genetic lineages of canine distemper virus in South America. Virus Res 163, 401–404, https://doi.org/10.1016/j.virusres.2011.10.008 (2012).21. Riley, M. C. & Wilkes, R. P. Sequencing of emerging canine distemper virus strain reveals new distinct genetic lineage in the United States associated with disease in wildlife and domestic canine populations. Virol J 12, 219, https://doi.org/10.1186/s12985-015-0445-7 (2015).22. Nikolin, V. M. et al. Canine distemper virus in the Serengeti ecosystem: molecular adaptation to different carnivore species. Mol Ecol 26, 2111–2130, https://doi.org/10.1111/mec.13902 (2017).Zhao, J. J. et al. Phylogenetic analysis of the haemagglutinin gene of canine distemper virus strains detected from breeding foxes, raccoon dogs and minks in China. Vet Microbiol 140, 34–42, https://doi.org/10.1016/j.vetmic.2009.07.010 (2010).Viral epidemiologyViral evolutionvirusdiseasePhylogenetic evidence of the intercontinental circulation of a Canine distemper virus lineage in the AmericasArtículohttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAtribucióninfo:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2PublicationORIGINALDuque-Valencia Scient Rep 2019.pdfDuque-Valencia Scient Rep 2019.pdfArticuloapplication/pdf3305220https://repository.ucc.edu.co/bitstreams/6c106538-c9b9-4afe-831d-44f8a94c93f3/download62c7520345965da8516efd82e291080aMD51Licencia_de_uso_Phylogenetic.pdfLicencia_de_uso_Phylogenetic.pdfFormato de 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