Using Brain spect with trodat in the Diagnosis of Substance Addiction
Introduction: the implementation of functional neuroimaging in the study of various neurological and psychiatric disorders allowed the use thereof as technique in the study of substance-related disorders. This research included the use of nuclear medicine tools in order to contribute to the diagnosi...
- Autores:
-
Franco Londoño, Jairo
Villa, Hooverman
Ocampo Serna, Sabina
Sierra Martelo, Carlos
Medina Osorio, Juan Carlos
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2016
- Institución:
- Universidad Cooperativa de Colombia
- Repositorio:
- Repositorio UCC
- Idioma:
- spa
- OAI Identifier:
- oai:repository.ucc.edu.co:20.500.12494/44325
- Acceso en línea:
- https://revistas.ucc.edu.co/index.php/ml/article/view/1587
https://hdl.handle.net/20.500.12494/44325
- Palabra clave:
- functional neuroimaging
forensic psychiatry
computer tomography for single photon emission
substance-related disorders
neuroimagen funcional
psiquiatría forense
tomografía computarizada de emisión de fotón único
trastornos relacionados con sustancias
neuroimagem funcional
psiquiatria forense
tomografia compudotarizada de emissão de fóton único
distúrbios relacionados com substâncias
- Rights
- openAccess
- License
- Derechos de autor 2016 Colombia Forense
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|
dc.title.eng.fl_str_mv |
Using Brain spect with trodat in the Diagnosis of Substance Addiction |
dc.title.spa.fl_str_mv |
Utilización de spect cerebral con trodat en el diagnóstico de adicción a sustancias |
dc.title.por.fl_str_mv |
Utilização de spect cerebral com trodat no diagnóstico de dependência a substâncias |
title |
Using Brain spect with trodat in the Diagnosis of Substance Addiction |
spellingShingle |
Using Brain spect with trodat in the Diagnosis of Substance Addiction functional neuroimaging forensic psychiatry computer tomography for single photon emission substance-related disorders neuroimagen funcional psiquiatría forense tomografía computarizada de emisión de fotón único trastornos relacionados con sustancias neuroimagem funcional psiquiatria forense tomografia compudotarizada de emissão de fóton único distúrbios relacionados com substâncias |
title_short |
Using Brain spect with trodat in the Diagnosis of Substance Addiction |
title_full |
Using Brain spect with trodat in the Diagnosis of Substance Addiction |
title_fullStr |
Using Brain spect with trodat in the Diagnosis of Substance Addiction |
title_full_unstemmed |
Using Brain spect with trodat in the Diagnosis of Substance Addiction |
title_sort |
Using Brain spect with trodat in the Diagnosis of Substance Addiction |
dc.creator.fl_str_mv |
Franco Londoño, Jairo Villa, Hooverman Ocampo Serna, Sabina Sierra Martelo, Carlos Medina Osorio, Juan Carlos |
dc.contributor.author.none.fl_str_mv |
Franco Londoño, Jairo Villa, Hooverman Ocampo Serna, Sabina Sierra Martelo, Carlos Medina Osorio, Juan Carlos |
dc.subject.eng.fl_str_mv |
functional neuroimaging forensic psychiatry computer tomography for single photon emission substance-related disorders |
topic |
functional neuroimaging forensic psychiatry computer tomography for single photon emission substance-related disorders neuroimagen funcional psiquiatría forense tomografía computarizada de emisión de fotón único trastornos relacionados con sustancias neuroimagem funcional psiquiatria forense tomografia compudotarizada de emissão de fóton único distúrbios relacionados com substâncias |
dc.subject.spa.fl_str_mv |
neuroimagen funcional psiquiatría forense tomografía computarizada de emisión de fotón único trastornos relacionados con sustancias |
dc.subject.por.fl_str_mv |
neuroimagem funcional psiquiatria forense tomografia compudotarizada de emissão de fóton único distúrbios relacionados com substâncias |
description |
Introduction: the implementation of functional neuroimaging in the study of various neurological and psychiatric disorders allowed the use thereof as technique in the study of substance-related disorders. This research included the use of nuclear medicine tools in order to contribute to the diagnosis of people with illegal psychoactive substance dependence. Materials and methods: A descriptive cross-sectional study was conducted on eight cases of patients between 18 and 44 years with known clinical disorder diagnosis due to dependence to multiple psychoactive substances, according to the dsm iv-tr criteria, which used the outpatient service of Clínica San Miguel Arcángel in Cartago, Colombia, in 2011. A perfusion brain spect imaging was implemented with trodat - 99mtc and the presence of different toxins in urine was confirmed through a multi drug method. Results: In the studies made with perfusion brain spect imaging with trodat - 99mtc, a reduction was found in the uptake of radiopharmaceutical in the base cores, in a bilateral and asymmetric manner with greater involvement of the putamen, compared to studies made in healthy individuals. Conclusion: The findings in this population of patients with substance dependence showed hypocaptation in the base nuclei through the implementation perfusion brain spect imaging with trodat - 99mtc, suggesting that this methodology could provide technical and scientific arguments to make positive or negative diagnoses on substance addiction. |
publishDate |
2016 |
dc.date.accessioned.none.fl_str_mv |
2022-03-02T16:45:20Z |
dc.date.available.none.fl_str_mv |
2022-03-02T16:45:20Z |
dc.date.none.fl_str_mv |
2016-04-01 |
dc.type.none.fl_str_mv |
Artículo |
dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
dc.type.coar.none.fl_str_mv |
http://purl.org/coar/resource_type/c_6501 |
dc.type.coarversion.none.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
dc.type.driver.none.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.redcol.none.fl_str_mv |
http://purl.org/redcol/resource_type/ART |
dc.type.version.none.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
http://purl.org/coar/resource_type/c_6501 |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
https://revistas.ucc.edu.co/index.php/ml/article/view/1587 10.16925/cf.v3i1.1587 |
dc.identifier.uri.none.fl_str_mv |
https://hdl.handle.net/20.500.12494/44325 |
url |
https://revistas.ucc.edu.co/index.php/ml/article/view/1587 https://hdl.handle.net/20.500.12494/44325 |
identifier_str_mv |
10.16925/cf.v3i1.1587 |
dc.language.none.fl_str_mv |
spa |
language |
spa |
dc.relation.none.fl_str_mv |
https://revistas.ucc.edu.co/index.php/ml/article/view/1587/1876 |
dc.rights.none.fl_str_mv |
Derechos de autor 2016 Colombia Forense |
dc.rights.accessrights.none.fl_str_mv |
info:eu-repo/semantics/openAccess |
dc.rights.coar.none.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
rights_invalid_str_mv |
Derechos de autor 2016 Colombia Forense http://purl.org/coar/access_right/c_abf2 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.spa.fl_str_mv |
Universidad Cooperativa de Colombia / Instituto Nacional de Medicina Legal y Ciencias Forenses |
dc.source.eng.fl_str_mv |
Colombia Forense; Vol. 3 No. 1; 23-30 |
dc.source.spa.fl_str_mv |
Colombia Forense; Vol. 3 Núm. 1; 23-30 |
dc.source.por.fl_str_mv |
Colombia Forense; v. 3 n. 1; 23-30 |
dc.source.none.fl_str_mv |
2145-9649 2145-0684 |
institution |
Universidad Cooperativa de Colombia |
repository.name.fl_str_mv |
Repositorio Institucional Universidad Cooperativa de Colombia |
repository.mail.fl_str_mv |
bdigital@metabiblioteca.com |
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1814246868403617792 |
spelling |
Franco Londoño, JairoVilla, HoovermanOcampo Serna, SabinaSierra Martelo, CarlosMedina Osorio, Juan Carlos2016-04-012022-03-02T16:45:20Z2022-03-02T16:45:20Zhttps://revistas.ucc.edu.co/index.php/ml/article/view/158710.16925/cf.v3i1.1587https://hdl.handle.net/20.500.12494/44325Introduction: the implementation of functional neuroimaging in the study of various neurological and psychiatric disorders allowed the use thereof as technique in the study of substance-related disorders. This research included the use of nuclear medicine tools in order to contribute to the diagnosis of people with illegal psychoactive substance dependence. Materials and methods: A descriptive cross-sectional study was conducted on eight cases of patients between 18 and 44 years with known clinical disorder diagnosis due to dependence to multiple psychoactive substances, according to the dsm iv-tr criteria, which used the outpatient service of Clínica San Miguel Arcángel in Cartago, Colombia, in 2011. A perfusion brain spect imaging was implemented with trodat - 99mtc and the presence of different toxins in urine was confirmed through a multi drug method. Results: In the studies made with perfusion brain spect imaging with trodat - 99mtc, a reduction was found in the uptake of radiopharmaceutical in the base cores, in a bilateral and asymmetric manner with greater involvement of the putamen, compared to studies made in healthy individuals. Conclusion: The findings in this population of patients with substance dependence showed hypocaptation in the base nuclei through the implementation perfusion brain spect imaging with trodat - 99mtc, suggesting that this methodology could provide technical and scientific arguments to make positive or negative diagnoses on substance addiction.Resumen. Introducción: la implementación de la neuroimagen funcional en el estudio de diferentes patologías neurológicas y psiquiátricas permitió que se usaran como técnicas en el estudio de los trastornos relacionados con sustancias. Esta investigación tomó herramientas de la medicina nuclear con el fin de aportar al diagnóstico de personas con dependencia a sustancias psicoactivas ilegales. Materiales y métodos: se realizó un estudio descriptivo y transversal de ocho casos de pacientes entre 18 y 44 años con diagnóstico clínico conocido de trastorno por dependencia a múltiples sustancias psicoactivas, de acuerdo con los criterios diagnósticos del dsm iv-tr, que utilizaron el servicio de consulta externa de la Clínica San Miguel Arcángel, en Cartago, Colombia, durante el 2011. Se implementó el procedimiento Gammagrafía spect de perfusión cerebral con trodat - 99mTc, y se confirmó la presencia de diferentes tóxicos en orina a través del método multi drug. Resultados: se encontró en los estudios realizados con gammagrafía spect de perfusión cerebral con trodat - 99mTc disminución en la captación del radio-fármaco en los núcleos de la base de manera bilateral y asimétrica, con mayor compromiso del putamen, comparado con estudios realizados en individuos sanos. Conclusión: los hallazgos en estapoblación de pacientes con dependencia a sustancias evidenció hipocaptación en los núcleos de la base mediante la implementación de gammagrafía spect de perfusión cerebral con trodat - 99mTc, lo cual sugiere que esta metodología podría aportar argumentos técnico-científicos para realizar diagnósticos positivos o negativos sobre adicción a sustancias.Introdução: a implementação da neuroimagem funcional no estudo de diferentes patologias neurológicas e psiquiátricas permitiu que fossem usadas como técnicas no estudo dos distúrbios relacionados com substâncias. Esta pesquisa usou ferramentas da medicina nuclear visando contribuir com o diagnóstico de pessoas com dependência a substâncias psicoativas ilícitas. Materiais e métodos: realizou-se um estudo descritivo e transversal de oito casos de pacientes entre 18 e 44 anos com diagnóstico clínico conhecido como distúrbio por dependência a múltiplas substancias psicoativas, de acordo com os critérios diagnósticos do dsm iv-tr, que utilizaram o serviço de consulta externa da Clínica San Miguel Arcángel, em Cartago, Colômbia, durante 2011. Implementou-se o procedimento Cintilografia spect cerebral com trodat - 99mtc, e foi confirmada a presença de diferentes tóxicos em urina através do método multi drug. Resultados: nos estudos realizados com cintilografia spect cerebral com trodat - 99mtc encontrou-se uma diminuição na captação do rádiofármaco nos núcleos da base de maneira bilateral e assimétrica, com maior comprometimento do putâmen, comparado com estudos realizados em sujeitos sadios. Conclusão: os achados nesta população de pacientes com dependência a substancias evidenciou hipocaptação nos núcleos da base mediante a implementação de cintilografia spect cerebral com trodat - 99mtc, sugerindo que esta metodologia poderia aportar argumentos técnico-científicos para realizar diagnósticos positivos ou negativos sobre dependência a substâncias.application/pdfspaUniversidad Cooperativa de Colombia / Instituto Nacional de Medicina Legal y Ciencias Forenseshttps://revistas.ucc.edu.co/index.php/ml/article/view/1587/1876Derechos de autor 2016 Colombia Forenseinfo:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Colombia Forense; Vol. 3 No. 1; 23-30Colombia Forense; Vol. 3 Núm. 1; 23-30Colombia Forense; v. 3 n. 1; 23-302145-96492145-0684functional neuroimagingforensic psychiatrycomputer tomography for single photon emissionsubstance-related disordersneuroimagen funcionalpsiquiatría forensetomografía computarizada de emisión de fotón únicotrastornos relacionados con sustanciasneuroimagem funcionalpsiquiatria forensetomografia compudotarizada de emissão de fóton únicodistúrbios relacionados com substânciasUsing Brain spect with trodat in the Diagnosis of Substance AddictionUtilización de spect cerebral con trodat en el diagnóstico de adicción a sustanciasUtilização de spect cerebral com trodat no diagnóstico de dependência a substânciasArtículohttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionPublication20.500.12494/44325oai:repository.ucc.edu.co:20.500.12494/443252024-07-16 13:25:17.055metadata.onlyhttps://repository.ucc.edu.coRepositorio Institucional Universidad Cooperativa de Colombiabdigital@metabiblioteca.com |