HLA genes in Barranquilla (North Colombia): Searching for cryptic Amerindian genes

America First Inhabitants population (Amerindians, Na Dene and Eskimos) underwent a drastic population reduction and gene exchange after Europeans and Africans arrival after 1492 AD. Barranquilla population may be a good model to study present day population admixture in South America. HLA-A, -B and...

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Autores:
Arnaiz-Villena A.
Bayona B.
Palacio-Gruber J.
Hernandez Aguirre, Enio Armando
Muñiz E.
Campos C.
Juarez I.
Gomez-Casado E.
Martín-Villa J.M.
Silvera C.
Tipo de recurso:
Article of journal
Fecha de publicación:
2017
Institución:
Universidad Cooperativa de Colombia
Repositorio:
Repositorio UCC
Idioma:
OAI Identifier:
oai:repository.ucc.edu.co:20.500.12494/41466
Acceso en línea:
https://doi.org/10.1016/j.molliq.2014.06.006
https://hdl.handle.net/20.500.12494/41466
Palabra clave:
African
Amerindian
Barranquilla
Caucasoid
Colombia
Cuba
HLA
Rights
closedAccess
License
http://purl.org/coar/access_right/c_14cb
Description
Summary:America First Inhabitants population (Amerindians, Na Dene and Eskimos) underwent a drastic population reduction and gene exchange after Europeans and Africans arrival after 1492 AD. Barranquilla population may be a good model to study present day population admixture in South America. HLA-A, -B and -DRB1 DNA typing has been performed in 188 unrelated individuals originated in the area and speak Spanish language; they showed apparent European/African and mixed characters. HLA genetic European/African features were found and only 1.85% Amerindian one. This contrasts with neighboring Cuban population where 10% HLA Amerindian characters appear. © 2017.