Prevalencia de linfocitosis monoclonal de células b y factores asociados: Metaanálisis 2002-2012

Introduction: studies on monoclonal B-cell lymphocytosis show wide divergence prevalence and limitations in its internal and external validity since the specificities of the groups studied; the majority of researchers use non-probability sampling and do not explain the bias control. Magnitude by sex...

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Autores:: Villegas-Gracia R.
Jaramillo Arbeláez P.
Cardona Arias, Jaiberth Antonio

Tipo de recurso:: Article of journal

Fecha de publicación:: 2015

Institución:: Universidad Cooperativa de Colombia

Repositorio:: Repositorio UCC

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spelling	Villegas-Gracia R.Jaramillo Arbeláez P.Cardona Arias, Jaiberth Antonio2021-12-16T22:16:39Z2021-12-16T22:16:39Z2015https://doi.org/10.7705/biomedica.v36i1.2612http://gasturbinespower.asmedigitalcollection.asme.org/article.aspx?articleid=142841608640289https://hdl.handle.net/20.500.12494/42977Villegas R,Jaramillo P,Cardona JA. Prevalencia de linfocitosis monoclonal de células b y factores asociados: Metaanálisis 2002-2012. Rev. Cuba. Hematol. Imunol. Hemoterapia. 2015. 31. (2):p. 172-186. .Introduction: studies on monoclonal B-cell lymphocytosis show wide divergence prevalence and limitations in its internal and external validity since the specificities of the groups studied; the majority of researchers use non-probability sampling and do not explain the bias control. Magnitude by sex and age group has not been analyzed, which do not allow the consolidation of a hypothesis about associated factors. Objective: to estimate the overall and specific prevalence of monoclonal B-cell lymphocytosis for sex and age, 2002-2012. Methods: a meta-analysis search for original investigations published in six databases. The overall and specific prevalence of monoclonal B-cell lymphocytosis was calculated by sex and type of population. Intervals were calculated for the difference in proportions between the prevalence in men and women and in general and sick population and with family history of chronic lymphocytic leukemia. Results: A prevalence of 7, 8 % of monoclonal lymphocytosis was found in a population of 18 527 individuals included in this study and no difference of prevalence in men (8,7 %) and women (7,8 %) was found, while in the comparison of the three analyzed populations the prevalence was statistically higher in patients (24 %), lower in the general population (6,7 %) and in individuals with family history of chronic lymphocytic leukemia (15 %). The prevalence of monoclonal Bcell lymphocytosis was higher in adults over 40 years. Conclusion: the higher prevalence corresponds to individuals underlying base diseases followed by relatives in first degree of patients with chronic lymphocytic leukemia; sex did not represent an associated factor with the presentation of monoclonal B-cell lymphocytosis. © 2015, Editorial Ciencias Medicas. All rights reserved.0000-0002-7101-929Xjaiberth.cardona@campusucc.edu.co186-172Editorial Ciencias MedicasageArticlechronic lymphatic leukemiafamily historygenderhumanmeta analysismonoclonal b cell lymphocytosisprevalencerisk factorPrevalencia de linfocitosis monoclonal de células b y factores asociados: Metaanálisis 2002-2012Artículohttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionRevista Cubana de Hematologia, Inmunologia y Hemoterapiainfo:eu-repo/semantics/closedAccesshttp://purl.org/coar/access_right/c_14cbPublication20.500.12494/42977oai:repository.ucc.edu.co:20.500.12494/429772024-08-20 16:20:40.447metadata.onlyhttps://repository.ucc.edu.coRepositorio Institucional Universidad Cooperativa de Colombiabdigital@metabiblioteca.com
dc.title.spa.fl_str_mv	Prevalencia de linfocitosis monoclonal de células b y factores asociados: Metaanálisis 2002-2012
title	Prevalencia de linfocitosis monoclonal de células b y factores asociados: Metaanálisis 2002-2012
spellingShingle	Prevalencia de linfocitosis monoclonal de células b y factores asociados: Metaanálisis 2002-2012 age Article chronic lymphatic leukemia family history gender human meta analysis monoclonal b cell lymphocytosis prevalence risk factor
title_short	Prevalencia de linfocitosis monoclonal de células b y factores asociados: Metaanálisis 2002-2012
title_full	Prevalencia de linfocitosis monoclonal de células b y factores asociados: Metaanálisis 2002-2012
title_fullStr	Prevalencia de linfocitosis monoclonal de células b y factores asociados: Metaanálisis 2002-2012
title_full_unstemmed	Prevalencia de linfocitosis monoclonal de células b y factores asociados: Metaanálisis 2002-2012
title_sort	Prevalencia de linfocitosis monoclonal de células b y factores asociados: Metaanálisis 2002-2012
dc.creator.fl_str_mv	Villegas-Gracia R. Jaramillo Arbeláez P. Cardona Arias, Jaiberth Antonio
dc.contributor.author.none.fl_str_mv	Villegas-Gracia R. Jaramillo Arbeláez P. Cardona Arias, Jaiberth Antonio
dc.subject.spa.fl_str_mv	age Article chronic lymphatic leukemia family history gender human meta analysis monoclonal b cell lymphocytosis prevalence risk factor
topic	age Article chronic lymphatic leukemia family history gender human meta analysis monoclonal b cell lymphocytosis prevalence risk factor
description	Introduction: studies on monoclonal B-cell lymphocytosis show wide divergence prevalence and limitations in its internal and external validity since the specificities of the groups studied; the majority of researchers use non-probability sampling and do not explain the bias control. Magnitude by sex and age group has not been analyzed, which do not allow the consolidation of a hypothesis about associated factors. Objective: to estimate the overall and specific prevalence of monoclonal B-cell lymphocytosis for sex and age, 2002-2012. Methods: a meta-analysis search for original investigations published in six databases. The overall and specific prevalence of monoclonal B-cell lymphocytosis was calculated by sex and type of population. Intervals were calculated for the difference in proportions between the prevalence in men and women and in general and sick population and with family history of chronic lymphocytic leukemia. Results: A prevalence of 7, 8 % of monoclonal lymphocytosis was found in a population of 18 527 individuals included in this study and no difference of prevalence in men (8,7 %) and women (7,8 %) was found, while in the comparison of the three analyzed populations the prevalence was statistically higher in patients (24 %), lower in the general population (6,7 %) and in individuals with family history of chronic lymphocytic leukemia (15 %). The prevalence of monoclonal Bcell lymphocytosis was higher in adults over 40 years. Conclusion: the higher prevalence corresponds to individuals underlying base diseases followed by relatives in first degree of patients with chronic lymphocytic leukemia; sex did not represent an associated factor with the presentation of monoclonal B-cell lymphocytosis. © 2015, Editorial Ciencias Medicas. All rights reserved.
publishDate	2015
dc.date.issued.none.fl_str_mv	2015
dc.date.accessioned.none.fl_str_mv	2021-12-16T22:16:39Z
dc.date.available.none.fl_str_mv	2021-12-16T22:16:39Z
dc.type.none.fl_str_mv	Artículo
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dc.type.coarversion.none.fl_str_mv	http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.driver.none.fl_str_mv	info:eu-repo/semantics/article
dc.type.redcol.none.fl_str_mv	http://purl.org/redcol/resource_type/ART
dc.type.version.none.fl_str_mv	info:eu-repo/semantics/publishedVersion
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dc.identifier.none.fl_str_mv	https://doi.org/10.7705/biomedica.v36i1.2612 http://gasturbinespower.asmedigitalcollection.asme.org/article.aspx?articleid=1428416
dc.identifier.issn.spa.fl_str_mv	08640289
dc.identifier.uri.none.fl_str_mv	https://hdl.handle.net/20.500.12494/42977
dc.identifier.bibliographicCitation.spa.fl_str_mv	Villegas R,Jaramillo P,Cardona JA. Prevalencia de linfocitosis monoclonal de células b y factores asociados: Metaanálisis 2002-2012. Rev. Cuba. Hematol. Imunol. Hemoterapia. 2015. 31. (2):p. 172-186. .
url	https://doi.org/10.7705/biomedica.v36i1.2612 http://gasturbinespower.asmedigitalcollection.asme.org/article.aspx?articleid=1428416 https://hdl.handle.net/20.500.12494/42977
identifier_str_mv	08640289 Villegas R,Jaramillo P,Cardona JA. Prevalencia de linfocitosis monoclonal de células b y factores asociados: Metaanálisis 2002-2012. Rev. Cuba. Hematol. Imunol. Hemoterapia. 2015. 31. (2):p. 172-186. .
dc.relation.ispartofjournal.spa.fl_str_mv	Revista Cubana de Hematologia, Inmunologia y Hemoterapia
dc.rights.accessrights.none.fl_str_mv	info:eu-repo/semantics/closedAccess
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dc.format.extent.spa.fl_str_mv	186-172
dc.publisher.spa.fl_str_mv	Editorial Ciencias Medicas
institution	Universidad Cooperativa de Colombia
repository.name.fl_str_mv	Repositorio Institucional Universidad Cooperativa de Colombia
repository.mail.fl_str_mv	bdigital@metabiblioteca.com
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Prevalencia de linfocitosis monoclonal de células b y factores asociados: Metaanálisis 2002-2012

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