Mutational analysis of BRCA1 and BRCA2 genes in women with familial breast cancer from different regions of Colombia.
The main risk factor for familial breast cancer is the presence of mutations in BRCA1 and BRCA2 genes. The prevalence of mutations in these genes is heterogeneous and varies according to geographical origin of studied families. In Colombia mutations in these genes have been mainly studied on patient...
- Autores:
-
Cortés C
Rivera AL
Trochez D
Solarte M
Gómez D
Cifuentes Cardona, Laura Fernanda
Barreto G
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2023
- Institución:
- Universidad Cooperativa de Colombia
- Repositorio:
- Repositorio UCC
- Idioma:
- OAI Identifier:
- oai:repository.ucc.edu.co:20.500.12494/50842
- Acceso en línea:
- https://doi.org/10.1186/s13053-019-0120-x
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85069179967&doi=10.1186%2fs13053-019-0120-x&partnerID=40&md5=5ed95ca87792f3d7a218c82536fdb3d1
https://hdl.handle.net/20.500.12494/50842
- Palabra clave:
- BRCA1
BRCA2
BREAST CANCER
FAMILIAL CANCER
GERMLINE MUTATIONS
- Rights
- openAccess
- License
- http://purl.org/coar/access_right/c_abf2
| Summary: | The main risk factor for familial breast cancer is the presence of mutations in BRCA1 and BRCA2 genes. The prevalence of mutations in these genes is heterogeneous and varies according to geographical origin of studied families. In Colombia mutations in these genes have been mainly studied on patients from Andean region. Bogot and Medellin presented its own battery of mutations. This study aims to identify mutations in BRCA1-2 genes in women with familial breast cancer from different regions of Colombia. |
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