Target-Specificity in scorpions; comparing lethality of scorpion venoms across arthropods and vertebrates
Artículo científico
- Autores:
-
Van der Meijden, Arie
Koch, Bjørn
Van der Valk, Tom
Vargas Muñoz, Leidy Johana
Estrada Gómez, Sebastián
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2017
- Institución:
- Universidad Cooperativa de Colombia
- Repositorio:
- Repositorio UCC
- Idioma:
- OAI Identifier:
- oai:repository.ucc.edu.co:20.500.12494/3368
- Acceso en línea:
- https://hdl.handle.net/20.500.12494/3368
- Palabra clave:
- Scorpions
Chicken
Venom
LD50
Zebrafish
Mealworm
Waxworm
- Rights
- openAccess
- License
- Licencia CC
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Target-Specificity in scorpions; comparing lethality of scorpion venoms across arthropods and vertebrates |
| title |
Target-Specificity in scorpions; comparing lethality of scorpion venoms across arthropods and vertebrates |
| spellingShingle |
Target-Specificity in scorpions; comparing lethality of scorpion venoms across arthropods and vertebrates Scorpions Chicken Venom LD50 Zebrafish Mealworm Waxworm |
| title_short |
Target-Specificity in scorpions; comparing lethality of scorpion venoms across arthropods and vertebrates |
| title_full |
Target-Specificity in scorpions; comparing lethality of scorpion venoms across arthropods and vertebrates |
| title_fullStr |
Target-Specificity in scorpions; comparing lethality of scorpion venoms across arthropods and vertebrates |
| title_full_unstemmed |
Target-Specificity in scorpions; comparing lethality of scorpion venoms across arthropods and vertebrates |
| title_sort |
Target-Specificity in scorpions; comparing lethality of scorpion venoms across arthropods and vertebrates |
| dc.creator.fl_str_mv |
Van der Meijden, Arie Koch, Bjørn Van der Valk, Tom Vargas Muñoz, Leidy Johana Estrada Gómez, Sebastián |
| dc.contributor.author.none.fl_str_mv |
Van der Meijden, Arie Koch, Bjørn Van der Valk, Tom Vargas Muñoz, Leidy Johana Estrada Gómez, Sebastián |
| dc.subject.spa.fl_str_mv |
Scorpions Chicken Venom LD50 Zebrafish Mealworm Waxworm |
| topic |
Scorpions Chicken Venom LD50 Zebrafish Mealworm Waxworm |
| description |
Artículo científico |
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2017 |
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2017-10-04 |
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2018-04-10T20:05:51Z |
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2018-04-10T20:05:51Z |
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Artículo |
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Van der Meijden, A., Koch, B., Van der Valk, T., Vargas Muñoz, L. J., y Estrada Gómez, S., (2017). Target-Specificity in Scorpions; Comparing Lethality of Scorpion Venoms across Arthropods and Vertebrates. Toxins 2017, 1-10, 312; doi:10.3390/toxins9100312 |
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https://hdl.handle.net/20.500.12494/3368 |
| identifier_str_mv |
Van der Meijden, A., Koch, B., Van der Valk, T., Vargas Muñoz, L. J., y Estrada Gómez, S., (2017). Target-Specificity in Scorpions; Comparing Lethality of Scorpion Venoms across Arthropods and Vertebrates. Toxins 2017, 1-10, 312; doi:10.3390/toxins9100312 |
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666359/ |
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Licencia CC |
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openAccess |
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Universidad Cooperativa de Colombia, Facultad de Ciencias de la Salud, Medicina, Medellín y Envigado |
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Medicina |
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Medellín |
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Universidad Cooperativa de Colombia |
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Van der Meijden, ArieKoch, BjørnVan der Valk, TomVargas Muñoz, Leidy JohanaEstrada Gómez, Sebastián2018-04-10T20:05:51Z2018-04-10T20:05:51Z2017-10-04https://hdl.handle.net/20.500.12494/3368Van der Meijden, A., Koch, B., Van der Valk, T., Vargas Muñoz, L. J., y Estrada Gómez, S., (2017). Target-Specificity in Scorpions; Comparing Lethality of Scorpion Venoms across Arthropods and Vertebrates. Toxins 2017, 1-10, 312; doi:10.3390/toxins9100312Artículo científicoScorpions use their venom in defensive situations as well as for subduing prey. Since some species of scorpion use their venom more in defensive situations than others, this may have led to selection for differences in effectiveness in defensive situations. Here, we compared the LD50 of the venom of 10 species of scorpions on five different species of target organisms; two insects and three vertebrates. We found little correlation between the target species in the efficacy of the different scorpion venoms. Only the two insects showed a positive correlation, indicating that they responded similarly to the panel of scorpion venoms. We discuss the lack of positive correlation between the vertebrate target species in the light of their evolution and development. When comparing the responses of the target systems to individual scorpion venoms pairwise, we found that closely related scorpion species tend to elicit a similar response pattern across the target species. This was further reflected in a significant phylogenetic signal across the scorpion phylogeny for the LD50 in mice and in zebrafish. We also provide the first mouse LD50 value for Grosphus grandidieri.leidy.vargasmu@campusucc.edu.coUniversidad Cooperativa de Colombia, Facultad de Ciencias de la Salud, Medicina, Medellín y EnvigadoMedicinaMedellínhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666359/ScorpionsChickenVenomLD50ZebrafishMealwormWaxwormTarget-Specificity in scorpions; comparing lethality of scorpion venoms across arthropods and vertebratesArtículohttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionLicencia CCinfo:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2PublicationTEXTTarget-Specificity in Scorpions; Comparing Lethality of Scorpion Venoms across Arthropods and Vertebrates.pdf.txtTarget-Specificity in Scorpions; Comparing Lethality of Scorpion Venoms across Arthropods and Vertebrates.pdf.txtExtracted texttext/plain40250https://repository.ucc.edu.co/bitstreams/8057e3cb-271e-47db-b729-f1334bc9a7f7/downloadfd933895346b3d7548c9ab6870c12635MD54Formato Licencia de uso.pdf.txtFormato Licencia de uso.pdf.txtExtracted texttext/plain4392https://repository.ucc.edu.co/bitstreams/7ffcd57d-2120-4e78-a96e-114a9bb98360/download2c43f0d1167c388d6994b2d4b0bd22efMD56THUMBNAILTarget-Specificity in Scorpions; Comparing Lethality of Scorpion Venoms across Arthropods and Vertebrates.pdf.jpgTarget-Specificity in Scorpions; Comparing Lethality of Scorpion Venoms across Arthropods and Vertebrates.pdf.jpgIM Thumbnailimage/jpeg6860https://repository.ucc.edu.co/bitstreams/5cc3551b-3ba8-4194-a5cf-5ee5ab252a0b/download26c24d2fa343234ec89e6985069d22b9MD55Formato Licencia de uso.pdf.jpgFormato Licencia de uso.pdf.jpgIM Thumbnailimage/jpeg5313https://repository.ucc.edu.co/bitstreams/7ba35314-d7aa-4937-a2e5-255d6c38897b/downloadcfb79eba048755a48755b0af7d620784MD57ORIGINALTarget-Specificity in Scorpions; Comparing Lethality of Scorpion Venoms across Arthropods and Vertebrates.pdfTarget-Specificity in Scorpions; Comparing Lethality of Scorpion Venoms across Arthropods and Vertebrates.pdfapplication/pdf326223https://repository.ucc.edu.co/bitstreams/4f40551a-b41b-46c1-aa45-953826ba19cb/download863b6393d4a5534f8d2b65e307b60d25MD51Formato Licencia de uso.pdfFormato Licencia de uso.pdfapplication/pdf215914https://repository.ucc.edu.co/bitstreams/d274365d-5e75-4f7b-b92f-c416bfe5d233/downloadb9be3f3834de28f7c374f809ae0bd756MD53LICENSElicense.txtlicense.txttext/plain; charset=utf-84514https://repository.ucc.edu.co/bitstreams/e5a732cd-7ebe-45ba-bdb3-2bec683bb542/downloadf3f5e184cacb7496a3e3345ca148d0f7MD5220.500.12494/3368oai:repository.ucc.edu.co:20.500.12494/33682024-08-10 22:44:58.81open.accesshttps://repository.ucc.edu.coRepositorio Institucional Universidad Cooperativa de Colombiabdigital@metabiblioteca.com |