Inflammatory status and severity of disease in dengue patients are associated with lipoprotein alterations.

The triggering of severe dengue has been associated with an exacerbated inflammatory process characterized by the production of pro-inflammatory cytokines such as IL-1/IL-18, which are the product of inflammasome activation. Furthermore, alteration in the levels of high-density (HDL) and low-density...

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Autores:
Marin Palma, D.
Sirois, C. M.
Urcuqui Inchima, S.
Hernández López, Juan Carlos
Tipo de recurso:
Article of journal
Fecha de publicación:
2023
Institución:
Universidad Cooperativa de Colombia
Repositorio:
Repositorio UCC
Idioma:
OAI Identifier:
oai:repository.ucc.edu.co:20.500.12494/50853
Acceso en línea:
https://doi.org/10.1371/journal.pone.0214245
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85063347774&doi=10.1371%2fjournal.pone.0214245&partnerID=40&md5=b4d6ec08f46c6220b903b5a197f62148
https://hdl.handle.net/20.500.12494/50853
Palabra clave:
ADULT
ARTICLE
C REACTIVE PROTEIN
CARRIER PROTEINS AND BINDING PROTEINS
CLINICAL ARTICLE
CONTROLLED STUDY
CROSS-SECTIONAL STUDY
CRYOPYRIN
DENGUE
DISEASE SEVERITY
FEMALE
GENE EXPRESSION
HIGH DENSITY LIPOPROTEIN
HUMAN
HUMAN CELL
INFLAMMASOME
INFLAMMATION
INTERLEUKIN 10
INTERLEUKIN 18
INTERLEUKIN 1BETA
INTERLEUKIN 1BETA CONVERTING ENZYME
INTERLEUKIN 6
LIPOPROTEIN
LOW DENSITY LIPOPROTEIN
MALE
MESSENGER RNA
PERIPHERAL BLOOD MONONUCLEAR CELL
PROTEIN BLOOD LEVEL
PROTEIN NLRC4
PROTEIN NLRP1
TUMOR NECROSIS FACTOR
UNCLASSIFIED DRUG
Rights
openAccess
License
http://purl.org/coar/access_right/c_abf2
id COOPER2_49fe24b0e9108bd1b8da4c17af46fe11
oai_identifier_str oai:repository.ucc.edu.co:20.500.12494/50853
network_acronym_str COOPER2
network_name_str Repositorio UCC
repository_id_str
spelling Marin Palma, D.Sirois, C. M.Urcuqui Inchima, S.Hernández López, Juan Carlos 2023-05-24T16:30:09Z2023-05-24T16:30:09Z22/03/2019https://doi.org/10.1371/journal.pone.0214245https://www.scopus.com/inward/record.uri?eid=2-s2.0-85063347774&doi=10.1371%2fjournal.pone.0214245&partnerID=40&md5=b4d6ec08f46c6220b903b5a197f6214819326203https://hdl.handle.net/20.500.12494/50853Marin-Palma D,Sirois CM,Urcuqui-Inchima S,Hernandez Lopez Juan carlos.Inflammatory status and severity of disease in dengue patients are associated with lipoprotein alterations..Plos One. 2019. 14. (3): e0214245The triggering of severe dengue has been associated with an exacerbated inflammatory process characterized by the production of pro-inflammatory cytokines such as IL-1/IL-18, which are the product of inflammasome activation. Furthermore, alteration in the levels of high-density (HDL) and low-density lipoproteins (LDL) has been observed; and HDL are known to have immunomodulatory properties, including the regulation of inflammasomes. While HDL would be expected to counteract hyperactivation of the inflammasome, the relationship between HDL and dengue severity, has not previously been explored.0000-0002-9200-5698juanc.hernandezl@campusucc.edu.coe0214245Public Library of ScienceADULTARTICLEC REACTIVE PROTEINCARRIER PROTEINS AND BINDING PROTEINSCLINICAL ARTICLECONTROLLED STUDYCROSS-SECTIONAL STUDYCRYOPYRINDENGUEDISEASE SEVERITYFEMALEGENE EXPRESSIONHIGH DENSITY LIPOPROTEINHUMANHUMAN CELLINFLAMMASOMEINFLAMMATIONINTERLEUKIN 10INTERLEUKIN 18INTERLEUKIN 1BETAINTERLEUKIN 1BETA CONVERTING ENZYMEINTERLEUKIN 6LIPOPROTEINLOW DENSITY LIPOPROTEINMALEMESSENGER RNAPERIPHERAL BLOOD MONONUCLEAR CELLPROTEIN BLOOD LEVELPROTEIN NLRC4PROTEIN NLRP1TUMOR NECROSIS FACTORUNCLASSIFIED DRUGInflammatory status and severity of disease in dengue patients are associated with lipoprotein alterations.Artículohttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionPlos Oneinfo:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Publication20.500.12494/50853oai:repository.ucc.edu.co:20.500.12494/508532024-08-20 16:16:56.386metadata.onlyhttps://repository.ucc.edu.coRepositorio Institucional Universidad Cooperativa de Colombiabdigital@metabiblioteca.com
dc.title.spa.fl_str_mv Inflammatory status and severity of disease in dengue patients are associated with lipoprotein alterations.
title Inflammatory status and severity of disease in dengue patients are associated with lipoprotein alterations.
spellingShingle Inflammatory status and severity of disease in dengue patients are associated with lipoprotein alterations.
ADULT
ARTICLE
C REACTIVE PROTEIN
CARRIER PROTEINS AND BINDING PROTEINS
CLINICAL ARTICLE
CONTROLLED STUDY
CROSS-SECTIONAL STUDY
CRYOPYRIN
DENGUE
DISEASE SEVERITY
FEMALE
GENE EXPRESSION
HIGH DENSITY LIPOPROTEIN
HUMAN
HUMAN CELL
INFLAMMASOME
INFLAMMATION
INTERLEUKIN 10
INTERLEUKIN 18
INTERLEUKIN 1BETA
INTERLEUKIN 1BETA CONVERTING ENZYME
INTERLEUKIN 6
LIPOPROTEIN
LOW DENSITY LIPOPROTEIN
MALE
MESSENGER RNA
PERIPHERAL BLOOD MONONUCLEAR CELL
PROTEIN BLOOD LEVEL
PROTEIN NLRC4
PROTEIN NLRP1
TUMOR NECROSIS FACTOR
UNCLASSIFIED DRUG
title_short Inflammatory status and severity of disease in dengue patients are associated with lipoprotein alterations.
title_full Inflammatory status and severity of disease in dengue patients are associated with lipoprotein alterations.
title_fullStr Inflammatory status and severity of disease in dengue patients are associated with lipoprotein alterations.
title_full_unstemmed Inflammatory status and severity of disease in dengue patients are associated with lipoprotein alterations.
title_sort Inflammatory status and severity of disease in dengue patients are associated with lipoprotein alterations.
dc.creator.fl_str_mv Marin Palma, D.
Sirois, C. M.
Urcuqui Inchima, S.
Hernández López, Juan Carlos
dc.contributor.author.none.fl_str_mv Marin Palma, D.
Sirois, C. M.
Urcuqui Inchima, S.
Hernández López, Juan Carlos
dc.subject.spa.fl_str_mv ADULT
ARTICLE
C REACTIVE PROTEIN
CARRIER PROTEINS AND BINDING PROTEINS
CLINICAL ARTICLE
CONTROLLED STUDY
CROSS-SECTIONAL STUDY
CRYOPYRIN
DENGUE
DISEASE SEVERITY
FEMALE
GENE EXPRESSION
HIGH DENSITY LIPOPROTEIN
HUMAN
HUMAN CELL
INFLAMMASOME
INFLAMMATION
INTERLEUKIN 10
INTERLEUKIN 18
INTERLEUKIN 1BETA
INTERLEUKIN 1BETA CONVERTING ENZYME
INTERLEUKIN 6
LIPOPROTEIN
LOW DENSITY LIPOPROTEIN
MALE
MESSENGER RNA
PERIPHERAL BLOOD MONONUCLEAR CELL
PROTEIN BLOOD LEVEL
PROTEIN NLRC4
PROTEIN NLRP1
TUMOR NECROSIS FACTOR
UNCLASSIFIED DRUG
topic ADULT
ARTICLE
C REACTIVE PROTEIN
CARRIER PROTEINS AND BINDING PROTEINS
CLINICAL ARTICLE
CONTROLLED STUDY
CROSS-SECTIONAL STUDY
CRYOPYRIN
DENGUE
DISEASE SEVERITY
FEMALE
GENE EXPRESSION
HIGH DENSITY LIPOPROTEIN
HUMAN
HUMAN CELL
INFLAMMASOME
INFLAMMATION
INTERLEUKIN 10
INTERLEUKIN 18
INTERLEUKIN 1BETA
INTERLEUKIN 1BETA CONVERTING ENZYME
INTERLEUKIN 6
LIPOPROTEIN
LOW DENSITY LIPOPROTEIN
MALE
MESSENGER RNA
PERIPHERAL BLOOD MONONUCLEAR CELL
PROTEIN BLOOD LEVEL
PROTEIN NLRC4
PROTEIN NLRP1
TUMOR NECROSIS FACTOR
UNCLASSIFIED DRUG
description The triggering of severe dengue has been associated with an exacerbated inflammatory process characterized by the production of pro-inflammatory cytokines such as IL-1/IL-18, which are the product of inflammasome activation. Furthermore, alteration in the levels of high-density (HDL) and low-density lipoproteins (LDL) has been observed; and HDL are known to have immunomodulatory properties, including the regulation of inflammasomes. While HDL would be expected to counteract hyperactivation of the inflammasome, the relationship between HDL and dengue severity, has not previously been explored.
publishDate 2023
dc.date.accessioned.none.fl_str_mv 2023-05-24T16:30:09Z
dc.date.available.none.fl_str_mv 2023-05-24T16:30:09Z
dc.date.issued.none.fl_str_mv 22/03/2019
dc.type.none.fl_str_mv Artículo
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.coar.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.coarversion.none.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.driver.none.fl_str_mv info:eu-repo/semantics/article
dc.type.redcol.none.fl_str_mv http://purl.org/redcol/resource_type/ART
dc.type.version.none.fl_str_mv info:eu-repo/semantics/publishedVersion
format http://purl.org/coar/resource_type/c_6501
status_str publishedVersion
dc.identifier.none.fl_str_mv https://doi.org/10.1371/journal.pone.0214245
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85063347774&doi=10.1371%2fjournal.pone.0214245&partnerID=40&md5=b4d6ec08f46c6220b903b5a197f62148
dc.identifier.issn.spa.fl_str_mv 19326203
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12494/50853
dc.identifier.bibliographicCitation.spa.fl_str_mv Marin-Palma D,Sirois CM,Urcuqui-Inchima S,Hernandez Lopez Juan carlos.Inflammatory status and severity of disease in dengue patients are associated with lipoprotein alterations..Plos One. 2019. 14. (3): e0214245
url https://doi.org/10.1371/journal.pone.0214245
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85063347774&doi=10.1371%2fjournal.pone.0214245&partnerID=40&md5=b4d6ec08f46c6220b903b5a197f62148
https://hdl.handle.net/20.500.12494/50853
identifier_str_mv 19326203
Marin-Palma D,Sirois CM,Urcuqui-Inchima S,Hernandez Lopez Juan carlos.Inflammatory status and severity of disease in dengue patients are associated with lipoprotein alterations..Plos One. 2019. 14. (3): e0214245
dc.relation.ispartofjournal.spa.fl_str_mv Plos One
dc.rights.accessrights.none.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.coar.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
rights_invalid_str_mv http://purl.org/coar/access_right/c_abf2
dc.format.extent.spa.fl_str_mv e0214245
dc.publisher.spa.fl_str_mv Public Library of Science
institution Universidad Cooperativa de Colombia
repository.name.fl_str_mv Repositorio Institucional Universidad Cooperativa de Colombia
repository.mail.fl_str_mv bdigital@metabiblioteca.com
_version_ 1814246693760139264

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