Uso terapéutico de plasma rico en plaquetas (prp) en endometritis persistente inducida por reproducción

La endometritis persistente después de la reproducción (PMIE) es una de las causas más frecuentes de subfertilidad en yeguas. Considerando que la inflamación persistente del endometrio lleva a un entorno uterino no apropiado para el descenso de un embrión. El plasma rico en plaquetas (PRP) es una op...

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Autores:: Verdugo Martínez, Laura Victoria
Melo Sánchez, Core Esmeralda

Tipo de recurso:: Trabajo de grado de pregrado

Fecha de publicación:: 2022

Institución:: Universidad Cooperativa de Colombia

Repositorio:: Repositorio UCC

Idioma:

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oai_identifier_str	oai:repository.ucc.edu.co:20.500.12494/44432
network_acronym_str	COOPER2
network_name_str	Repositorio UCC
repository_id_str
dc.title.spa.fl_str_mv	Uso terapéutico de plasma rico en plaquetas (prp) en endometritis persistente inducida por reproducción
title	Uso terapéutico de plasma rico en plaquetas (prp) en endometritis persistente inducida por reproducción
spellingShingle	Uso terapéutico de plasma rico en plaquetas (prp) en endometritis persistente inducida por reproducción Plasma rico en plaquetas Inflamación Inmunomodulación Endometritis TG 2022 MVZ 44432 Platelet-rich plasma Inflammation Immunomodulation Endometritis
title_short	Uso terapéutico de plasma rico en plaquetas (prp) en endometritis persistente inducida por reproducción
title_full	Uso terapéutico de plasma rico en plaquetas (prp) en endometritis persistente inducida por reproducción
title_fullStr	Uso terapéutico de plasma rico en plaquetas (prp) en endometritis persistente inducida por reproducción
title_full_unstemmed	Uso terapéutico de plasma rico en plaquetas (prp) en endometritis persistente inducida por reproducción
title_sort	Uso terapéutico de plasma rico en plaquetas (prp) en endometritis persistente inducida por reproducción
dc.creator.fl_str_mv	Verdugo Martínez, Laura Victoria Melo Sánchez, Core Esmeralda
dc.contributor.author.none.fl_str_mv	Verdugo Martínez, Laura Victoria Melo Sánchez, Core Esmeralda
dc.subject.spa.fl_str_mv	Plasma rico en plaquetas Inflamación Inmunomodulación Endometritis
topic	Plasma rico en plaquetas Inflamación Inmunomodulación Endometritis TG 2022 MVZ 44432 Platelet-rich plasma Inflammation Immunomodulation Endometritis
dc.subject.classification.spa.fl_str_mv	TG 2022 MVZ 44432
dc.subject.other.spa.fl_str_mv	Platelet-rich plasma Inflammation Immunomodulation Endometritis
description	La endometritis persistente después de la reproducción (PMIE) es una de las causas más frecuentes de subfertilidad en yeguas. Considerando que la inflamación persistente del endometrio lleva a un entorno uterino no apropiado para el descenso de un embrión. El plasma rico en plaquetas (PRP) es una opción terapéutica para yeguas susceptibles a PBIE en vista de su aplicación ascendente en la regeneración tisular por la concentración de factores de crecimiento (FC) con capacidades antiinflamatorias. La metodología de búsqueda de literatura incluyo el uso de términos relacionados con el tema en base de datos PubMed y ScienceDirect. Esta revisión, contextualiza los mecanismos de defensa uterina describiendo la respuesta inmune innata. También se revisa la endometritis, agentes asociados al desencadenamiento de la misma. Métodos diagnósticos y tratamientos tradicionales. En los últimos años se han implementado diferentes terapias alternativas, entre ellas el plasma rico en plaquetas. En este documento se aborda el plasma rico en plaquetas desde su concepto, mecanismos en la modulación inflamatoria y estudios de éxito en la aplicación en yeguas susceptibles a PBIE.
publishDate	2022
dc.date.accessioned.none.fl_str_mv	2022-03-18T16:10:13Z
dc.date.available.none.fl_str_mv	2022-03-18T16:10:13Z 2022-02-09
dc.date.issued.none.fl_str_mv	2022-02-09
dc.type.none.fl_str_mv	Trabajo de grado - Pregrado
dc.type.coar.none.fl_str_mv	http://purl.org/coar/resource_type/c_7a1f
dc.type.driver.none.fl_str_mv	info:eu-repo/semantics/bachelorThesis
dc.type.version.none.fl_str_mv	info:eu-repo/semantics/acceptedVersion
format	http://purl.org/coar/resource_type/c_7a1f
status_str	acceptedVersion
dc.identifier.uri.none.fl_str_mv	https://hdl.handle.net/20.500.12494/44432
dc.identifier.bibliographicCitation.spa.fl_str_mv	Verdugo Martínez, L. V. y Melo Sánchez, C. E. (2022). Uso terapéutico de plasma rico en plaquetas (prp) en endometritis persistente inducida por reproducción. [Tesis de pregrado, Universidad Cooperativa de Colombia]. Repositorio Institucional UCC. http://hdl.handle.net/20.500.12494/44432
url	https://hdl.handle.net/20.500.12494/44432
identifier_str_mv	Verdugo Martínez, L. V. y Melo Sánchez, C. E. (2022). Uso terapéutico de plasma rico en plaquetas (prp) en endometritis persistente inducida por reproducción. [Tesis de pregrado, Universidad Cooperativa de Colombia]. Repositorio Institucional UCC. http://hdl.handle.net/20.500.12494/44432
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spelling	Verdugo Martínez, Laura VictoriaMelo Sánchez, Core Esmeralda2022-03-18T16:10:13Z2022-03-18T16:10:13Z2022-02-092022-02-09https://hdl.handle.net/20.500.12494/44432Verdugo Martínez, L. V. y Melo Sánchez, C. E. (2022). Uso terapéutico de plasma rico en plaquetas (prp) en endometritis persistente inducida por reproducción. [Tesis de pregrado, Universidad Cooperativa de Colombia]. Repositorio Institucional UCC. http://hdl.handle.net/20.500.12494/44432La endometritis persistente después de la reproducción (PMIE) es una de las causas más frecuentes de subfertilidad en yeguas. Considerando que la inflamación persistente del endometrio lleva a un entorno uterino no apropiado para el descenso de un embrión. El plasma rico en plaquetas (PRP) es una opción terapéutica para yeguas susceptibles a PBIE en vista de su aplicación ascendente en la regeneración tisular por la concentración de factores de crecimiento (FC) con capacidades antiinflamatorias. La metodología de búsqueda de literatura incluyo el uso de términos relacionados con el tema en base de datos PubMed y ScienceDirect. Esta revisión, contextualiza los mecanismos de defensa uterina describiendo la respuesta inmune innata. También se revisa la endometritis, agentes asociados al desencadenamiento de la misma. Métodos diagnósticos y tratamientos tradicionales. En los últimos años se han implementado diferentes terapias alternativas, entre ellas el plasma rico en plaquetas. En este documento se aborda el plasma rico en plaquetas desde su concepto, mecanismos en la modulación inflamatoria y estudios de éxito en la aplicación en yeguas susceptibles a PBIE.Persistent endometritis after reproduction (PMIE) is one of the most common causes of subfertility in mares. Whereas persistent inflammation of the endometrium leads to a uterine environment not suitable for the descent of an embryo. Platelet-rich plasma (PRP) is a therapeutic option for mares susceptible to PBIE in view of its upward application in tissue regeneration by the concentration of growth factors (CF) with anti-inflammatory capabilities. The literature search methodology included the use of terms related to the topic in the PubMed and ScienceDirect database. This review contextualizes uterine defense mechanisms by describing the innate immune response. Endometritis, agents associated with triggering it, are also reviewed. Traditional diagnostic methods and treatments. In recent years, different alternative therapies have been implemented, including platelet-rich plasma. This paper addresses platelet-rich plasma, from its concept, mechanisms in inflammatory modulation and successful studies in the application in mares susceptible to PBIE.core.melo@campusucc.edu.colauraverdugo2911@gmail.com58 p.AraucaUniversidad Cooperativa de Colombia, Facultad de Ciencias de la Salud, Medicina Veterinaría y Zootecnia, AraucaMedicina veterinaria y zootecniaPlasma rico en plaquetasInflamaciónInmunomodulaciónEndometritisTG 2022 MVZ 44432Platelet-rich plasmaInflammationImmunomodulationEndometritisUso terapéutico de plasma rico en plaquetas (prp) en endometritis persistente inducida por reproducciónTrabajo de grado - Pregradohttp://purl.org/coar/resource_type/c_7a1finfo:eu-repo/semantics/bachelorThesisinfo:eu-repo/semantics/acceptedVersionAtribución – Sin Derivarinfo:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Abel, Margaret H., and D. T. 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DePalo. 2000. “Anti-Inflammatory Cytokines.” Chest 117(4). doi: 10.1378/chest.117.4.1162.PublicationLICENSElicense.txtlicense.txttext/plain; charset=utf-84334https://repository.ucc.edu.co/bitstreams/b85fb205-40fd-4f5e-80e8-3d8c56542a7b/download3bce4f7ab09dfc588f126e1e36e98a45MD54ORIGINAL2022_uso_terapeutico_plasma.pdf2022_uso_terapeutico_plasma.pdfTrabajo de gradoapplication/pdf603511https://repository.ucc.edu.co/bitstreams/8178739e-1130-4996-b752-6b79570b42ee/downloadaad6a39e104eb42c87bc95b3951eba30MD512022_uso_terapeutico_plasma-FormatoLicenciaUso.pdf2022_uso_terapeutico_plasma-FormatoLicenciaUso.pdfLicencia de 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12:47:06.69open.accesshttps://repository.ucc.edu.coRepositorio Institucional Universidad Cooperativa de Colombiabdigital@metabiblioteca.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Uso terapéutico de plasma rico en plaquetas (prp) en endometritis persistente inducida por reproducción

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