Time-course investigation of the gene expression profile during Fasciola hepatica infection: A microarray-based study

Fasciolosis is listed as one of the most important neglected tropical diseases according with the World Health Organization and is also considered as a reemerging disease in the human beings. Despite there are several studies describing the immune response induced by Fasciola hepatica in the mammali...

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Autores:
Rojas Caraballo, José Vicente
López Aban, Julio
Fernández Soto, Pedro
Vicente, Belén
Collia, Francisco
Muro, Antonio
Tipo de recurso:
Article of journal
Fecha de publicación:
2015
Institución:
Universidad Cooperativa de Colombia
Repositorio:
Repositorio UCC
Idioma:
OAI Identifier:
oai:repository.ucc.edu.co:20.500.12494/998
Acceso en línea:
https://hdl.handle.net/20.500.12494/998
Palabra clave:
Fasciolosis
Gene expression
Rights
openAccess
License
Licencia CC
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dc.title.spa.fl_str_mv Time-course investigation of the gene expression profile during Fasciola hepatica infection: A microarray-based study
title Time-course investigation of the gene expression profile during Fasciola hepatica infection: A microarray-based study
spellingShingle Time-course investigation of the gene expression profile during Fasciola hepatica infection: A microarray-based study
Fasciolosis
Gene expression
title_short Time-course investigation of the gene expression profile during Fasciola hepatica infection: A microarray-based study
title_full Time-course investigation of the gene expression profile during Fasciola hepatica infection: A microarray-based study
title_fullStr Time-course investigation of the gene expression profile during Fasciola hepatica infection: A microarray-based study
title_full_unstemmed Time-course investigation of the gene expression profile during Fasciola hepatica infection: A microarray-based study
title_sort Time-course investigation of the gene expression profile during Fasciola hepatica infection: A microarray-based study
dc.creator.fl_str_mv Rojas Caraballo, José Vicente
López Aban, Julio
Fernández Soto, Pedro
Vicente, Belén
Collia, Francisco
Muro, Antonio
dc.contributor.author.none.fl_str_mv Rojas Caraballo, José Vicente
López Aban, Julio
Fernández Soto, Pedro
Vicente, Belén
Collia, Francisco
Muro, Antonio
dc.subject.spa.fl_str_mv Fasciolosis
Gene expression
topic Fasciolosis
Gene expression
description Fasciolosis is listed as one of the most important neglected tropical diseases according with the World Health Organization and is also considered as a reemerging disease in the human beings. Despite there are several studies describing the immune response induced by Fasciola hepatica in the mammalian host, investigations aimed at identifying the expression profile of genes involved in inducing hepatic injury are currently scarce. Data presented here belong to a time-course investigation of the gene expression profile in the liver of BALB/c mice infected with F. hepatica metacercariae at 7 and 21 days after experimental infection. The data published here have been deposited in NCBI's Gene Expression Omnibus and are accessible through GEO Series accession number GSE69588, previously published by Rojas-Caraballo et al. (2015) in PLoS One
publishDate 2015
dc.date.issued.none.fl_str_mv 2015-08-22
dc.date.accessioned.none.fl_str_mv 2017-08-10T00:23:29Z
dc.date.available.none.fl_str_mv 2017-08-10T00:23:29Z
dc.type.none.fl_str_mv Artículo
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dc.identifier.bibliographicCitation.spa.fl_str_mv Rojas Caraballo, J. et al. (2015). Time-course investigation of the gene expression profile during Fasciola hepatica infection: A microarray-based study. / Genomics Data 6 (2015) 89–91
url https://hdl.handle.net/20.500.12494/998
identifier_str_mv Rojas Caraballo, J. et al. (2015). Time-course investigation of the gene expression profile during Fasciola hepatica infection: A microarray-based study. / Genomics Data 6 (2015) 89–91
dc.relation.isversionof.spa.fl_str_mv https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664735/
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eu_rights_str_mv openAccess
dc.publisher.spa.fl_str_mv Universidad Cooperativa de Colombia, Facultad de Ciencias de la Salud, Programa de Medicina, Santa Marta, Colombia
institution Universidad Cooperativa de Colombia
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spelling Rojas Caraballo, José VicenteLópez Aban, JulioFernández Soto, PedroVicente, BelénCollia, FranciscoMuro, Antonio2017-08-10T00:23:29Z2017-08-10T00:23:29Z2015-08-22https://hdl.handle.net/20.500.12494/998Rojas Caraballo, J. et al. (2015). Time-course investigation of the gene expression profile during Fasciola hepatica infection: A microarray-based study. / Genomics Data 6 (2015) 89–91Fasciolosis is listed as one of the most important neglected tropical diseases according with the World Health Organization and is also considered as a reemerging disease in the human beings. Despite there are several studies describing the immune response induced by Fasciola hepatica in the mammalian host, investigations aimed at identifying the expression profile of genes involved in inducing hepatic injury are currently scarce. Data presented here belong to a time-course investigation of the gene expression profile in the liver of BALB/c mice infected with F. hepatica metacercariae at 7 and 21 days after experimental infection. The data published here have been deposited in NCBI's Gene Expression Omnibus and are accessible through GEO Series accession number GSE69588, previously published by Rojas-Caraballo et al. (2015) in PLoS Onejosev.rojas@campusucc.edu.cojlaban@usal.espfsoto@usal.esbelvi25@usal.esama@usal.esUniversidad Cooperativa de Colombia, Facultad de Ciencias de la Salud, Programa de Medicina, Santa Marta, Colombiahttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664735/FasciolosisGene expressionTime-course investigation of the gene expression profile during Fasciola hepatica infection: A microarray-based studyArtículohttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionLicencia CCinfo:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2PublicationORIGINAL1.pdf1.pdfapplication/pdf248802https://repository.ucc.edu.co/bitstreams/43ecd13c-0d03-41bf-95d5-fb6d67a4bc78/downloadab3cdda08253e85b75227fe79335af06MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repository.ucc.edu.co/bitstreams/1209842d-6a9d-4e13-9436-9a5539e74ab4/download8a4605be74aa9ea9d79846c1fba20a33MD52TEXT1.pdf.txt1.pdf.txtExtracted texttext/plain11949https://repository.ucc.edu.co/bitstreams/15447978-be5c-47e9-931e-13b3015a7786/download10dbac54230e1244d6e030c65a7e6230MD53THUMBNAIL1.pdf.jpg1.pdf.jpgIM Thumbnailimage/jpeg18785https://repository.ucc.edu.co/bitstreams/f086298c-708c-4cb5-8011-8bc393714660/download18a921d95a215cb316b19fb696d6576cMD5420.500.12494/998oai:repository.ucc.edu.co:20.500.12494/9982024-08-10 22:46:25.054open.accesshttps://repository.ucc.edu.coRepositorio Institucional Universidad Cooperativa de Colombiabdigital@metabiblioteca.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