Time-course investigation of the gene expression profile during Fasciola hepatica infection: A microarray-based study

Fasciolosis is listed as one of the most important neglected tropical diseases according with the World Health Organization and is also considered as a reemerging disease in the human beings. Despite there are several studies describing the immune response induced by Fasciola hepatica in the mammali...

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Autores:
Rojas Caraballo, José Vicente
López Aban, Julio
Fernández Soto, Pedro
Vicente, Belén
Collia, Francisco
Muro, Antonio
Tipo de recurso:
Article of journal
Fecha de publicación:
2015
Institución:
Universidad Cooperativa de Colombia
Repositorio:
Repositorio UCC
Idioma:
OAI Identifier:
oai:repository.ucc.edu.co:20.500.12494/998
Acceso en línea:
https://hdl.handle.net/20.500.12494/998
Palabra clave:
Fasciolosis
Gene expression
Rights
openAccess
License
Licencia CC
Description
Summary:Fasciolosis is listed as one of the most important neglected tropical diseases according with the World Health Organization and is also considered as a reemerging disease in the human beings. Despite there are several studies describing the immune response induced by Fasciola hepatica in the mammalian host, investigations aimed at identifying the expression profile of genes involved in inducing hepatic injury are currently scarce. Data presented here belong to a time-course investigation of the gene expression profile in the liver of BALB/c mice infected with F. hepatica metacercariae at 7 and 21 days after experimental infection. The data published here have been deposited in NCBI's Gene Expression Omnibus and are accessible through GEO Series accession number GSE69588, previously published by Rojas-Caraballo et al. (2015) in PLoS One