Solution thermodynamics and preferential solvation of sulfamethazine in (methanol + water) mixtures

Artículo de investigación

Autores:
Delgado, Daniel Ricardo
Almanza Montero, Ovidio Amado
Martínez, Fleming
Peña, María A.
Jouyban, Abolghasem
Acree Jr, William Eugene
Tipo de recurso:
Article of journal
Fecha de publicación:
2016
Institución:
Universidad Cooperativa de Colombia
Repositorio:
Repositorio UCC
Idioma:
OAI Identifier:
oai:repository.ucc.edu.co:20.500.12494/1015
Acceso en línea:
https://hdl.handle.net/20.500.12494/1015
Palabra clave:
Sulfamethazine
Methanol
Solubility
Jouyban–Acree model
Activity coefficient
Solution thermodynamic quantities
Preferential solvation
Rights
closedAccess
License
Licencia CC
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repository_id_str
dc.title.spa.fl_str_mv Solution thermodynamics and preferential solvation of sulfamethazine in (methanol + water) mixtures
title Solution thermodynamics and preferential solvation of sulfamethazine in (methanol + water) mixtures
spellingShingle Solution thermodynamics and preferential solvation of sulfamethazine in (methanol + water) mixtures
Sulfamethazine
Methanol
Solubility
Jouyban–Acree model
Activity coefficient
Solution thermodynamic quantities
Preferential solvation
title_short Solution thermodynamics and preferential solvation of sulfamethazine in (methanol + water) mixtures
title_full Solution thermodynamics and preferential solvation of sulfamethazine in (methanol + water) mixtures
title_fullStr Solution thermodynamics and preferential solvation of sulfamethazine in (methanol + water) mixtures
title_full_unstemmed Solution thermodynamics and preferential solvation of sulfamethazine in (methanol + water) mixtures
title_sort Solution thermodynamics and preferential solvation of sulfamethazine in (methanol + water) mixtures
dc.creator.fl_str_mv Delgado, Daniel Ricardo
Almanza Montero, Ovidio Amado
Martínez, Fleming
Peña, María A.
Jouyban, Abolghasem
Acree Jr, William Eugene
dc.contributor.author.none.fl_str_mv Delgado, Daniel Ricardo
Almanza Montero, Ovidio Amado
Martínez, Fleming
Peña, María A.
Jouyban, Abolghasem
Acree Jr, William Eugene
dc.subject.spa.fl_str_mv Sulfamethazine
Methanol
Solubility
Jouyban–Acree model
Activity coefficient
Solution thermodynamic quantities
Preferential solvation
topic Sulfamethazine
Methanol
Solubility
Jouyban–Acree model
Activity coefficient
Solution thermodynamic quantities
Preferential solvation
description Artículo de investigación
publishDate 2016
dc.date.issued.none.fl_str_mv 2016-02-08
dc.date.accessioned.none.fl_str_mv 2017-08-10T20:30:48Z
dc.date.available.none.fl_str_mv 2017-08-10T20:30:48Z
dc.type.none.fl_str_mv Artículo
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dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12494/1015
dc.identifier.bibliographicCitation.spa.fl_str_mv Daniel R. Delgado, Ovidio A. Almanza , Fleming Martínez, María A. Peña, Abolghasem Jouyban, William E. Acree Jr. Solution thermodynamics and preferential solvation of sulfamethazine in (methanol + water) mixtures. J. Chem. Thermodynamics 97 (2016) 264–276
url https://hdl.handle.net/20.500.12494/1015
identifier_str_mv Daniel R. Delgado, Ovidio A. Almanza , Fleming Martínez, María A. Peña, Abolghasem Jouyban, William E. Acree Jr. Solution thermodynamics and preferential solvation of sulfamethazine in (methanol + water) mixtures. J. Chem. Thermodynamics 97 (2016) 264–276
dc.relation.isversionof.spa.fl_str_mv http://www.sciencedirect.com/science/article/pii/S0021961416000525
dc.rights.cc.none.fl_str_mv Licencia CC
dc.rights.accessrights.none.fl_str_mv info:eu-repo/semantics/closedAccess
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rights_invalid_str_mv Licencia CC
http://purl.org/coar/access_right/c_14cb
eu_rights_str_mv closedAccess
dc.publisher.spa.fl_str_mv Universidad Cooperativa de Colombia, Facultad de Ingenierías, Programa de Ingeniería Industrial, Neiva, Colombia, 00000
dc.publisher.program.spa.fl_str_mv Ingeniería Industrial
dc.publisher.place.spa.fl_str_mv Neiva
institution Universidad Cooperativa de Colombia
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spelling Delgado, Daniel RicardoAlmanza Montero, Ovidio AmadoMartínez, FlemingPeña, María A.Jouyban, AbolghasemAcree Jr, William Eugene2017-08-10T20:30:48Z2017-08-10T20:30:48Z2016-02-08https://hdl.handle.net/20.500.12494/1015Daniel R. Delgado, Ovidio A. Almanza , Fleming Martínez, María A. Peña, Abolghasem Jouyban, William E. Acree Jr. Solution thermodynamics and preferential solvation of sulfamethazine in (methanol + water) mixtures. J. Chem. Thermodynamics 97 (2016) 264–276Artículo de investigaciónThe solubility of sulfamethazine (SMT) in {methanol (1) + water (2)} co-solvent mixtures was determined at five different temperatures from (293.15 to 313.15) K. The sulfonamide exhibited its highest mole frac- tion solubility in pure methanol (d1 = 29.6 MPa1/2) and its lowest mole fraction solubility in water (d2 = 47.8 MPa1/2) at each of the five temperatures studied. The Jouyban–Acree model was used to corre- late/predict the solubility values. The respective apparent thermodynamic functions Gibbs energy, enthalpy, and entropy of solution were obtained from the solubility data through the van’t Hoff and Gibbs equations. Apparent thermodynamic quantities of mixing were also calculated for this drug using values of the ideal solubility reported in the literature. A non-linear enthalpy–entropy relationship was noted for SMT in plots of both the enthalpy vs. Gibbs energy of mixing and the enthalpy vs. entropy of mixing. These plots suggest two different trends according to the slopes obtained when the composition of the mixtures changes. Accordingly, the mechanism for SMT transfer processes in water-rich mixtures from water to the mixture with 0.70 in mass fraction of methanol is entropy driven. Conversely, the mechanism is enthalpy driven in mixtures whenever the methanol composition exceeds 0.70 mol frac- tion. An inverse Kirkwood–Buff integral analysis of the preferential solvation of SMT indicated that the drug is preferentially solvated by water in water-rich mixtures but is preferentially solvated by methanol in methanol-rich mixtures.1. Introduction. 2. Experimental. 2.1. Reagents. 2.2. Preparation of solvent mixtures. 2.3. Solubility determinations. 2.4. Calorimetric study. 2.5. X-ray diffraction analysis. 3. Results and discussion. 3.1. Equilibrium solubility of SMT. 3.2. Log-linear model of Yalkowsky. 3.3. Jouyban–Acree model. 3.4. Activity coefficients of SMT. 3.5. Apparent thermodynamic quantities of SMT dissolution. 3.6. Apparent thermodynamic quantities of SMT mixing. 3.7. Enthalpy–entropy compensation analysis of SMT. 3.8. Preferential solvation of SMT. 4. Conclusions. Acknowledgments. References.danielr.delgado@campusucc.edu.coUniversidad Cooperativa de Colombia, Facultad de Ingenierías, Programa de Ingeniería Industrial, Neiva, Colombia, 00000Ingeniería IndustrialNeivahttp://www.sciencedirect.com/science/article/pii/S0021961416000525SulfamethazineMethanolSolubilityJouyban–Acree modelActivity coefficientSolution thermodynamic quantitiesPreferential solvationSolution thermodynamics and preferential solvation of sulfamethazine in (methanol + water) mixturesArtículohttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionLicencia CCinfo:eu-repo/semantics/closedAccesshttp://purl.org/coar/access_right/c_14cbPublicationORIGINAL2016_Solution thermodynamics and preferential solvation of sulfamethazine.pdf2016_Solution thermodynamics and preferential solvation of 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