Sociodemographic and clinical profile of a population with acute heart failure: MED-ICA cohort

Objective: To determine the epidemiological characteristics of adults with acute heart failure admitted to a University Hospital. Method: A retrospective, descriptive cohort study conducted by reviewing the medical notes of patients over 18 years-old and admitted between July and December 2015 to a hospital in Medellin, Colombia. Results: The study included 361 patients with acute heart failure, with a mean age of 76 years, and of whom 193 (53.4%) were women. A reduced ejection fraction (LVEF) was observed in 183 (50.6%) patients, 19 (5.2%) with an intermediate LVEF, and 148 (40.9%) with normal LEVF. The pharmacological treatment prior to admission included angiotensin-converting-enzyme (ACE) inhibitors / angiotensin II receptor antagonists (ARA2) in 253 (70%) patients, a beta-blocker in 212 (58.7%), and spironolactone in 92 (25.4%). The main cause of acute heart failure was the presence of tachy-brady-arrhythmias (17.5%), followed by infection (17.2%), and exacerbation of chronic pulmonary disease (16.3%). The clinical classification of the decompensation was Stevenson B in 335 (92.7%) patients, Stevenson C in 20 (5.5%), and Stevenson L in 6 (1.6%). The mean admission time was 6 (4-9) days. There were 30 (8.3%) deaths, 50% due to infections associated with cardiac decompensation and 20% due to acute coronary syndrome. Conclusion: Similarities were found with international studies, but there was a higher mortality mainly linked to infection as a decompensation precipitating factor. The triggering factors and aetiology are presented, which are useful data in clinical practice. There was a high level of comorbidities, and their decompensation had a significant impact on the exacerbation of heart failure. The sub-group with the intermediate ejection fraction had features that require further characterisation. © 2018 Sociedad Colombiana de Cardiología y Cirugía Cardiovascular

• Autores: Muñoz Mejia, Oscar Arlex; Sierra Varga, Elsy Cristina; Zapata-Cárdenas A.; Isaza-Montoya M.; Muñoz-Cifuentes M.A.; Sánchez-Echavarría J.D.; Echeverri-García J.; En Nombre Del Grupo De Investigacion En Medicina Interna (Gimi); Facultad De Medicina; Universidad De Antioquia-Ips Universitaria
• Tipo de recurso: Article of journal
• Fecha de publicación: 2018
• Institución: Universidad Cooperativa de Colombia
• Repositorio: Repositorio UCC
• OAI Identifier: oai:repository.ucc.edu.co:20.500.12494/41576
• Acceso en línea: https://doi.org/10.1108/WWOP-04-2017-0010; https://www.scopus.com/inward/record.uri?eid=2-s2.0-85054099058&doi=10.3303%2fCET1867094&partnerID=40&md5=1875a; https://hdl.handle.net/20.500.12494/41576
• Palabra clave: Acute heart failure; Mortality; Risk factors
• Rights: closedAccess
• License: http://purl.org/coar/access_right/c_14cb