Evidence of over-dominance for sickle cell trait in a population sample from Buenaventura, Colombia

Sickle cell disease is a hereditary disease caused by a hemoglobin variant, known as hemoglobin S.This hemoglobin variant has a high frequency in areas where malaria is prevalent, because heterozygous genotype has a protective action against malaria infec

Autores:
Fong Reales, Cristian javier
Tipo de recurso:
Article of journal
Fecha de publicación:
2023
Institución:
Universidad Cooperativa de Colombia
Repositorio:
Repositorio UCC
Idioma:
OAI Identifier:
oai:repository.ucc.edu.co:20.500.12494/50243
Acceso en línea:
https://doi.org/10.5897/IJGMB2014.0106
https://academicjournals.org/journal/IJGMB/article-abstract/8E4460450921
https://hdl.handle.net/20.500.12494/50243
Palabra clave:
BUENAVENTURA
FITNESS
HEMOGLOBIN S
MLARIA RESISTANT
OVER-DOMINANCE
SELECTION COEFFICIENT.
Rights
openAccess
License
http://purl.org/coar/access_right/c_abf2
Description
Summary:Sickle cell disease is a hereditary disease caused by a hemoglobin variant, known as hemoglobin S.This hemoglobin variant has a high frequency in areas where malaria is prevalent, because heterozygous genotype has a protective action against malaria infec