Sulfasalazine as an Immunomodulator of the Inflammatory Process during HIV-1 Infection.

HIV-1 induces an uncontrolled inflammatory response of several immune components, such as inflammasomes. These molecular complexes, associated with Toll-like receptor (TLR) activity, induce the maturation and release of IL-1 and IL-18 and eventually induce pyroptosis. It has been previously demonstr...

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Autores:
Feria Garzón, M. G.
Rugeles, M. T.
Hernández López, Juan Carlos
Lujan, J. A.
Taborda, N. A
Tipo de recurso:
Article of journal
Fecha de publicación:
2023
Institución:
Universidad Cooperativa de Colombia
Repositorio:
Repositorio UCC
Idioma:
OAI Identifier:
oai:repository.ucc.edu.co:20.500.12494/50852
Acceso en línea:
https://doi.org/10.3390/ijms20184476
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85072150393&doi=10.3390%2fijms20184476&partnerID=40&md5=6b30345a684c5d474f3c2271bcde9352
https://hdl.handle.net/20.500.12494/50852
Palabra clave:
HIV
INFLAMMASOMES
INFLAMMATION
SULFASALAZINE
TOLL-LIKE RECEPTORS
Rights
openAccess
License
http://purl.org/coar/access_right/c_abf2
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oai_identifier_str oai:repository.ucc.edu.co:20.500.12494/50852
network_acronym_str COOPER2
network_name_str Repositorio UCC
repository_id_str
spelling Feria Garzón, M. G.Rugeles, M. T.Hernández López, Juan Carlos Lujan, J. A.Taborda, N. A2023-05-24T16:30:09Z2023-05-24T16:30:09Z11/09/2019https://doi.org/10.3390/ijms20184476https://www.scopus.com/inward/record.uri?eid=2-s2.0-85072150393&doi=10.3390%2fijms20184476&partnerID=40&md5=6b30345a684c5d474f3c2271bcde935216616596https://hdl.handle.net/20.500.12494/50852Feria-Garzón MG,Rugeles MT,Hernandez Lopez Juan carlos,Lujan JA,Taborda NA.Sulfasalazine as an Immunomodulator of the Inflammatory Process during HIV-1 Infection..INT J MOL SCI. 2019. 20. (18): 4476HIV-1 induces an uncontrolled inflammatory response of several immune components, such as inflammasomes. These molecular complexes, associated with Toll-like receptor (TLR) activity, induce the maturation and release of IL-1 and IL-18 and eventually induce pyroptosis. It has been previously demonstrated that HIV induces inflammasome activation, which is significantly lower in the gastrointestinal tissue and blood from people living with HIV-1 with spontaneous control of viral replication. Therefore, immunomodulatory agents could be useful in improving HIV prognosis.0000-0002-9200-5698juanc.hernandezl@campusucc.edu.co4476Multidisciplinary Digital Publishing Institute (MDPI)HIVINFLAMMASOMESINFLAMMATIONSULFASALAZINETOLL-LIKE RECEPTORSSulfasalazine as an Immunomodulator of the Inflammatory Process during HIV-1 Infection.Artículohttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionINT J MOL SCIinfo:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Publication20.500.12494/50852oai:repository.ucc.edu.co:20.500.12494/508522024-08-20 16:21:58.457metadata.onlyhttps://repository.ucc.edu.coRepositorio Institucional Universidad Cooperativa de Colombiabdigital@metabiblioteca.com
dc.title.spa.fl_str_mv Sulfasalazine as an Immunomodulator of the Inflammatory Process during HIV-1 Infection.
title Sulfasalazine as an Immunomodulator of the Inflammatory Process during HIV-1 Infection.
spellingShingle Sulfasalazine as an Immunomodulator of the Inflammatory Process during HIV-1 Infection.
HIV
INFLAMMASOMES
INFLAMMATION
SULFASALAZINE
TOLL-LIKE RECEPTORS
title_short Sulfasalazine as an Immunomodulator of the Inflammatory Process during HIV-1 Infection.
title_full Sulfasalazine as an Immunomodulator of the Inflammatory Process during HIV-1 Infection.
title_fullStr Sulfasalazine as an Immunomodulator of the Inflammatory Process during HIV-1 Infection.
title_full_unstemmed Sulfasalazine as an Immunomodulator of the Inflammatory Process during HIV-1 Infection.
title_sort Sulfasalazine as an Immunomodulator of the Inflammatory Process during HIV-1 Infection.
dc.creator.fl_str_mv Feria Garzón, M. G.
Rugeles, M. T.
Hernández López, Juan Carlos
Lujan, J. A.
Taborda, N. A
dc.contributor.author.none.fl_str_mv Feria Garzón, M. G.
Rugeles, M. T.
Hernández López, Juan Carlos
Lujan, J. A.
Taborda, N. A
dc.subject.spa.fl_str_mv HIV
INFLAMMASOMES
INFLAMMATION
SULFASALAZINE
TOLL-LIKE RECEPTORS
topic HIV
INFLAMMASOMES
INFLAMMATION
SULFASALAZINE
TOLL-LIKE RECEPTORS
description HIV-1 induces an uncontrolled inflammatory response of several immune components, such as inflammasomes. These molecular complexes, associated with Toll-like receptor (TLR) activity, induce the maturation and release of IL-1 and IL-18 and eventually induce pyroptosis. It has been previously demonstrated that HIV induces inflammasome activation, which is significantly lower in the gastrointestinal tissue and blood from people living with HIV-1 with spontaneous control of viral replication. Therefore, immunomodulatory agents could be useful in improving HIV prognosis.
publishDate 2023
dc.date.issued.none.fl_str_mv 11/09/2019
dc.date.accessioned.none.fl_str_mv 2023-05-24T16:30:09Z
dc.date.available.none.fl_str_mv 2023-05-24T16:30:09Z
dc.type.none.fl_str_mv Artículo
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.coar.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.coarversion.none.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.driver.none.fl_str_mv info:eu-repo/semantics/article
dc.type.redcol.none.fl_str_mv http://purl.org/redcol/resource_type/ART
dc.type.version.none.fl_str_mv info:eu-repo/semantics/publishedVersion
format http://purl.org/coar/resource_type/c_6501
status_str publishedVersion
dc.identifier.none.fl_str_mv https://doi.org/10.3390/ijms20184476
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85072150393&doi=10.3390%2fijms20184476&partnerID=40&md5=6b30345a684c5d474f3c2271bcde9352
dc.identifier.issn.spa.fl_str_mv 16616596
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12494/50852
dc.identifier.bibliographicCitation.spa.fl_str_mv Feria-Garzón MG,Rugeles MT,Hernandez Lopez Juan carlos,Lujan JA,Taborda NA.Sulfasalazine as an Immunomodulator of the Inflammatory Process during HIV-1 Infection..INT J MOL SCI. 2019. 20. (18): 4476
url https://doi.org/10.3390/ijms20184476
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85072150393&doi=10.3390%2fijms20184476&partnerID=40&md5=6b30345a684c5d474f3c2271bcde9352
https://hdl.handle.net/20.500.12494/50852
identifier_str_mv 16616596
Feria-Garzón MG,Rugeles MT,Hernandez Lopez Juan carlos,Lujan JA,Taborda NA.Sulfasalazine as an Immunomodulator of the Inflammatory Process during HIV-1 Infection..INT J MOL SCI. 2019. 20. (18): 4476
dc.relation.ispartofjournal.spa.fl_str_mv INT J MOL SCI
dc.rights.accessrights.none.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.coar.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
rights_invalid_str_mv http://purl.org/coar/access_right/c_abf2
dc.format.extent.spa.fl_str_mv 4476
dc.publisher.spa.fl_str_mv Multidisciplinary Digital Publishing Institute (MDPI)
institution Universidad Cooperativa de Colombia
repository.name.fl_str_mv Repositorio Institucional Universidad Cooperativa de Colombia
repository.mail.fl_str_mv bdigital@metabiblioteca.com
_version_ 1814247203897606144

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