Study of Colombia North Wiwa El Encanto Amerindians HLA- genes: Pacific Islanders relatedness

We have studied Wiwa/Sanja Amerindians HLA-A, -B, -C, -DRB1 and DQB1 allele frequencies and extended haplotypes in 52 unrelated individuals from “El Encanto” town at Guanachaca riverside. High frequency alleles were in general present in other Amerindian populations. Also, three extended haplotypes...

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Autores:
Arnaiz Villena, Antonio
Palacio Grüber, Jose
Juarez, Ignacio
Muñiz, Ester
Hernández Aguirre, Enio Armando
Bayona, Brayan
Campos, Cristina
Nuñez, Jorge
Lopez Nares, Adrian
Martin Villa, Manuel
Silvera Redondo, Carlos
Tipo de recurso:
Article of journal
Fecha de publicación:
2018
Institución:
Universidad Cooperativa de Colombia
Repositorio:
Repositorio UCC
Idioma:
OAI Identifier:
oai:repository.ucc.edu.co:20.500.12494/4649
Acceso en línea:
https://hdl.handle.net/20.500.12494/4649
Palabra clave:
HLA
Wiwa
Amerindians
Colombia
South America
America Peopling
Pharmacogenomics
Transplantation
Epidemiology
Rights
openAccess
License
Licencia CC
id COOPER2_1320f22884ba713627433a126cf8bf8d
oai_identifier_str oai:repository.ucc.edu.co:20.500.12494/4649
network_acronym_str COOPER2
network_name_str Repositorio UCC
repository_id_str
dc.title.spa.fl_str_mv Study of Colombia North Wiwa El Encanto Amerindians HLA- genes: Pacific Islanders relatedness
title Study of Colombia North Wiwa El Encanto Amerindians HLA- genes: Pacific Islanders relatedness
spellingShingle Study of Colombia North Wiwa El Encanto Amerindians HLA- genes: Pacific Islanders relatedness
HLA
Wiwa
Amerindians
Colombia
South America
America Peopling
Pharmacogenomics
Transplantation
Epidemiology
title_short Study of Colombia North Wiwa El Encanto Amerindians HLA- genes: Pacific Islanders relatedness
title_full Study of Colombia North Wiwa El Encanto Amerindians HLA- genes: Pacific Islanders relatedness
title_fullStr Study of Colombia North Wiwa El Encanto Amerindians HLA- genes: Pacific Islanders relatedness
title_full_unstemmed Study of Colombia North Wiwa El Encanto Amerindians HLA- genes: Pacific Islanders relatedness
title_sort Study of Colombia North Wiwa El Encanto Amerindians HLA- genes: Pacific Islanders relatedness
dc.creator.fl_str_mv Arnaiz Villena, Antonio
Palacio Grüber, Jose
Juarez, Ignacio
Muñiz, Ester
Hernández Aguirre, Enio Armando
Bayona, Brayan
Campos, Cristina
Nuñez, Jorge
Lopez Nares, Adrian
Martin Villa, Manuel
Silvera Redondo, Carlos
dc.contributor.author.none.fl_str_mv Arnaiz Villena, Antonio
Palacio Grüber, Jose
Juarez, Ignacio
Muñiz, Ester
Hernández Aguirre, Enio Armando
Bayona, Brayan
Campos, Cristina
Nuñez, Jorge
Lopez Nares, Adrian
Martin Villa, Manuel
Silvera Redondo, Carlos
dc.subject.spa.fl_str_mv HLA
Wiwa
Amerindians
Colombia
South America
America Peopling
Pharmacogenomics
Transplantation
Epidemiology
topic HLA
Wiwa
Amerindians
Colombia
South America
America Peopling
Pharmacogenomics
Transplantation
Epidemiology
description We have studied Wiwa/Sanja Amerindians HLA-A, -B, -C, -DRB1 and DQB1 allele frequencies and extended haplotypes in 52 unrelated individuals from “El Encanto” town at Guanachaca riverside. High frequency alleles were in general present in other Amerindian populations. Also, three extended haplotypes and eight ones were respectively both “new found” and already described in Amerindians from North, Central and South America, including Lakota-Sioux, Mayas, Teeneks, Quechua and Aymaras. Analyses of HLA-A*24:02 and -C*01:02 Wiwa high frequency alleles suggested a specific relatedness with another Amerindian and Pacific Islander ethnic groups (these two particular alleles bearing in high frequencies); they include New Zealand Maoris, Taiwanese, Japanese, Papua New Guinea, and Samoans among others. This may indicate that selective forces are maintaining these two alleles high frequency within this wide American/Pacific area.
publishDate 2018
dc.date.accessioned.none.fl_str_mv 2018-06-29T22:01:42Z
dc.date.available.none.fl_str_mv 2018-06-29T22:01:42Z
dc.date.issued.none.fl_str_mv 2018-07
dc.type.none.fl_str_mv Artículo
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
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dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12494/4649
dc.identifier.bibliographicCitation.spa.fl_str_mv Arnaiz, V. A., Palacio,G. J., Juareza, I., Hernández, E., Muñiz, E., Bayona, B., Campos, C., et al. (2018). Study of Colombia North Wiwa El Encanto Amerindians HLA- genes: Pacific Islanders relatedness. Human Immunology, 79, 530–531
url https://hdl.handle.net/20.500.12494/4649
identifier_str_mv Arnaiz, V. A., Palacio,G. J., Juareza, I., Hernández, E., Muñiz, E., Bayona, B., Campos, C., et al. (2018). Study of Colombia North Wiwa El Encanto Amerindians HLA- genes: Pacific Islanders relatedness. Human Immunology, 79, 530–531
dc.relation.isversionof.spa.fl_str_mv https://doi.org/10.1016/j.humimm.2018.04.016
dc.rights.cc.none.fl_str_mv Licencia CC
dc.rights.accessrights.none.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.coar.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
rights_invalid_str_mv Licencia CC
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.publisher.spa.fl_str_mv Universidad Cooperativa de Colombia, Facultad de Ciencias de la Salud, Medicina, Santa Marta
dc.publisher.program.spa.fl_str_mv Medicina
dc.publisher.place.spa.fl_str_mv Santa Marta
institution Universidad Cooperativa de Colombia
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spelling Arnaiz Villena, AntonioPalacio Grüber, JoseJuarez, IgnacioMuñiz, EsterHernández Aguirre, Enio ArmandoBayona, BrayanCampos, CristinaNuñez, JorgeLopez Nares, AdrianMartin Villa, ManuelSilvera Redondo, Carlos2018-06-29T22:01:42Z2018-06-29T22:01:42Z2018-07https://hdl.handle.net/20.500.12494/4649Arnaiz, V. A., Palacio,G. J., Juareza, I., Hernández, E., Muñiz, E., Bayona, B., Campos, C., et al. (2018). Study of Colombia North Wiwa El Encanto Amerindians HLA- genes: Pacific Islanders relatedness. Human Immunology, 79, 530–531We have studied Wiwa/Sanja Amerindians HLA-A, -B, -C, -DRB1 and DQB1 allele frequencies and extended haplotypes in 52 unrelated individuals from “El Encanto” town at Guanachaca riverside. High frequency alleles were in general present in other Amerindian populations. Also, three extended haplotypes and eight ones were respectively both “new found” and already described in Amerindians from North, Central and South America, including Lakota-Sioux, Mayas, Teeneks, Quechua and Aymaras. Analyses of HLA-A*24:02 and -C*01:02 Wiwa high frequency alleles suggested a specific relatedness with another Amerindian and Pacific Islander ethnic groups (these two particular alleles bearing in high frequencies); they include New Zealand Maoris, Taiwanese, Japanese, Papua New Guinea, and Samoans among others. This may indicate that selective forces are maintaining these two alleles high frequency within this wide American/Pacific area.aarnaiz@med.ucm.esenio.hernandez@campusucc.edu.coUniversidad Cooperativa de Colombia, Facultad de Ciencias de la Salud, Medicina, Santa MartaMedicinaSanta Martahttps://doi.org/10.1016/j.humimm.2018.04.016HLAWiwaAmerindiansColombiaSouth AmericaAmerica PeoplingPharmacogenomicsTransplantationEpidemiologyStudy of Colombia North Wiwa El Encanto Amerindians HLA- genes: Pacific Islanders relatednessArtículohttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionLicencia CCinfo:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2http://orcid.org/0000-0003-1196-3956PublicationLICENSElicense.txtlicense.txttext/plain; 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