Neuropsychiatric Alterations in a Patient Diagnosed with Advanced Korsakoff’s Syndrome: Clinical Case of Low Incidence and Prevalence in Colombia

Korsakoff’s syndrome (KS) is an insidious and progressive neuropsychiatric disorder that affects specific neurocognitive functioning, especially in tasks that require sustained attention, memory, executive functions, and visuospatial functioning. Usually, this disease generates neuropsychiatric comp...

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Autores:
Hurtado González, Carlos Alberto
Ospina Otalvaro, Sebastian
Marmolejo Escobar, Carlos Steven
Quebrada Mera, Karen Julieth
Ortega Bolaños, Lucely
Gutiérrez Lenis, Paola Andrea
Herrera Montoya, Valentina
Saldarriaga Viveros, Luis Miguel
Beltrán Alomia, Juan Pablo
Ayala Rico, Juan Felipe
Torres Colorado, Luigui Andres
Tipo de recurso:
Article of investigation
Fecha de publicación:
2022
Institución:
Universidad Cooperativa de Colombia
Repositorio:
Repositorio UCC
Idioma:
eng
OAI Identifier:
oai:repository.ucc.edu.co:20.500.12494/54991
Acceso en línea:
https://hdl.handle.net/20.500.12494/54991
https://doi.org/10.1155/2022/2772594
Palabra clave:
Korsakoff’s syndrome (KS)
Neurocognitive functioning
Sustained attention
Memory
Executive functions
Visuospatial functioning
Alcoholism
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closedAccess
License
https://creativecommons.org/licenses/by-nc-nd/4.0/
id COOPER2_11328de935ef79f7d179f356299fa382
oai_identifier_str oai:repository.ucc.edu.co:20.500.12494/54991
network_acronym_str COOPER2
network_name_str Repositorio UCC
repository_id_str
dc.title.none.fl_str_mv Neuropsychiatric Alterations in a Patient Diagnosed with Advanced Korsakoff’s Syndrome: Clinical Case of Low Incidence and Prevalence in Colombia
title Neuropsychiatric Alterations in a Patient Diagnosed with Advanced Korsakoff’s Syndrome: Clinical Case of Low Incidence and Prevalence in Colombia
spellingShingle Neuropsychiatric Alterations in a Patient Diagnosed with Advanced Korsakoff’s Syndrome: Clinical Case of Low Incidence and Prevalence in Colombia
Korsakoff’s syndrome (KS)
Neurocognitive functioning
Sustained attention
Memory
Executive functions
Visuospatial functioning
Alcoholism
title_short Neuropsychiatric Alterations in a Patient Diagnosed with Advanced Korsakoff’s Syndrome: Clinical Case of Low Incidence and Prevalence in Colombia
title_full Neuropsychiatric Alterations in a Patient Diagnosed with Advanced Korsakoff’s Syndrome: Clinical Case of Low Incidence and Prevalence in Colombia
title_fullStr Neuropsychiatric Alterations in a Patient Diagnosed with Advanced Korsakoff’s Syndrome: Clinical Case of Low Incidence and Prevalence in Colombia
title_full_unstemmed Neuropsychiatric Alterations in a Patient Diagnosed with Advanced Korsakoff’s Syndrome: Clinical Case of Low Incidence and Prevalence in Colombia
title_sort Neuropsychiatric Alterations in a Patient Diagnosed with Advanced Korsakoff’s Syndrome: Clinical Case of Low Incidence and Prevalence in Colombia
dc.creator.fl_str_mv Hurtado González, Carlos Alberto
Ospina Otalvaro, Sebastian
Marmolejo Escobar, Carlos Steven
Quebrada Mera, Karen Julieth
Ortega Bolaños, Lucely
Gutiérrez Lenis, Paola Andrea
Herrera Montoya, Valentina
Saldarriaga Viveros, Luis Miguel
Beltrán Alomia, Juan Pablo
Ayala Rico, Juan Felipe
Torres Colorado, Luigui Andres
dc.contributor.author.none.fl_str_mv Hurtado González, Carlos Alberto
Ospina Otalvaro, Sebastian
Marmolejo Escobar, Carlos Steven
Quebrada Mera, Karen Julieth
Ortega Bolaños, Lucely
Gutiérrez Lenis, Paola Andrea
Herrera Montoya, Valentina
Saldarriaga Viveros, Luis Miguel
Beltrán Alomia, Juan Pablo
Ayala Rico, Juan Felipe
Torres Colorado, Luigui Andres
dc.subject.proposal.none.fl_str_mv Korsakoff’s syndrome (KS)
Neurocognitive functioning
Sustained attention
Memory
Executive functions
Visuospatial functioning
Alcoholism
topic Korsakoff’s syndrome (KS)
Neurocognitive functioning
Sustained attention
Memory
Executive functions
Visuospatial functioning
Alcoholism
description Korsakoff’s syndrome (KS) is an insidious and progressive neuropsychiatric disorder that affects specific neurocognitive functioning, especially in tasks that require sustained attention, memory, executive functions, and visuospatial functioning. Usually, this disease generates neuropsychiatric complications that worsen the quality of life (QOL) of patients in the medium term. We present a case of a 63-year-old male who presented with a diagnosis of advanced Korsakoff’s syndrome and has a clinical history of recurrent memory loss and a history of alcohol abuse. The patient showed difficulty manipulating immediate information, associated with a possible frontal lobe dysfunction, and inability to remember material given through the auditory pathway. The patient showed a psychiatric clinical picture which is constantly worsening his and his immediate caregiver’s QOL. The data obtained demonstrate that the patient presents a progressive cognitive impairment, which in the short term is correlated with Korsakoff-type dementia. It is suggested to carry out functional neurorehabilitation plans aimed at improving the QOL of the patient, his immediate caregiver, and future people with this type of diagnosis.
publishDate 2022
dc.date.issued.none.fl_str_mv 2022-12
dc.date.accessioned.none.fl_str_mv 2024-02-20T16:48:56Z
dc.date.available.none.fl_str_mv 2024-02-20T16:48:56Z
dc.type.none.fl_str_mv Artículos Científicos
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dc.identifier.citation.none.fl_str_mv Alberto Hurtado Gonzalez, C., Ospina Otalvaro, S., Marmolejo Escobar, C. S., Quebrada Mera, K. J., Arango de la Pava, P. M., Clavijo, C. A., Ortega Bolaños, L., Rátiva Hernández, N., Vidal Rosero, A. M., Gutierrez Lenis, P. A., Lucumí, A., Cappellaro Sánchez, J. P., Zamorano, A. A., Jacome, J. P., Herrera Montoya, V., Saldarriaga, L. M., Prado Salcedo, C., Alvarado Carranza, S. F., Marín Hoyos, C. A., … Arias Díaz, J. A. (2022). Neuropsychiatric Alterations in a Patient Diagnosed with Advanced Korsakoff’s Syndrome: Clinical Case of Low Incidence and Prevalence in Colombia. Case Reports in Medicine, 2022, 2772594–2772596. https://doi.org/10.1155/2022/2772594
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12494/54991
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1155/2022/2772594
dc.identifier.eissn.none.fl_str_mv 16879635
identifier_str_mv Alberto Hurtado Gonzalez, C., Ospina Otalvaro, S., Marmolejo Escobar, C. S., Quebrada Mera, K. J., Arango de la Pava, P. M., Clavijo, C. A., Ortega Bolaños, L., Rátiva Hernández, N., Vidal Rosero, A. M., Gutierrez Lenis, P. A., Lucumí, A., Cappellaro Sánchez, J. P., Zamorano, A. A., Jacome, J. P., Herrera Montoya, V., Saldarriaga, L. M., Prado Salcedo, C., Alvarado Carranza, S. F., Marín Hoyos, C. A., … Arias Díaz, J. A. (2022). Neuropsychiatric Alterations in a Patient Diagnosed with Advanced Korsakoff’s Syndrome: Clinical Case of Low Incidence and Prevalence in Colombia. Case Reports in Medicine, 2022, 2772594–2772596. https://doi.org/10.1155/2022/2772594
16879635
url https://hdl.handle.net/20.500.12494/54991
https://doi.org/10.1155/2022/2772594
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.citationvolume.none.fl_str_mv 12
dc.relation.ispartofjournal.none.fl_str_mv Case Reports in Medicin
dc.relation.references.none.fl_str_mv E. Isenberg-Grzeda, Y. Alici, V. Hatzoglou, C. Nelson, W. Breitbart, "Nonalcoholic thiamine-related encephalopathy (Wernicke-Korsakoff syndrome) among inpatients with cancer: a series of 18 cases," Psychosomatics, vol. 57 no. 1, pp. 71-81, DOI: 10.1016/j.psym.2015.10.001, 2016.
R. Schliebs, T. Arendt, "The cholinergic system in aging and neuronal degeneration," Behavioural Brain Research, vol. 221 no. 2, pp. 555-563, DOI: 10.1016/j.bbr.2010.11.058, 2011.
A. Anjum, "The amnestic syndrome," The Medical Basis of Psychiatry, pp. 43-51, 2016.
P. J. Langlais, L. M. Savage, "Thiamine deficiency in rats produces cognitive and memory deficits on spatial tasks that correlate with tissue loss in diencephalon, cortex and white matter," Behavioural Brain Research, vol. 68 no. 1, pp. 75-89, DOI: 10.1016/0166-4328(94)00162-9, 1995.
N. Butters, J. Brandt, "The continuity hypothesis the relationship of long-term alcoholism to the wernicke-korsakoff syndrome," Recent Developments in Alcoholism, pp. 207-226, 1985.
M. Oscar‐Berman, S. M. Kirkley, D. A. Gansler, A. Couture, "Comparisons of Korsakoff and non‐korsakoff alcoholics on neuropsychological tests of prefrontal brain functioning," Alcoholism: Clinical and Experimental Research, vol. 28 no. 4, pp. 667-675, DOI: 10.1097/01.alc.0000122761.09179.b9, 2004.
M. Oscar-Bemian, H. E. Schendan, "Asymmetries of brain function in alcoholism: relationship to aging," Neurobehavior of Language and Cognition, pp. 213-240, 2002.
K. M. Adams, S. Gilman, R. A. Koeppe, K. J. Kluin, J. A. Brunberg, D. Dede, S. Berent, P. D. Kroll, "Neuropsychological deficits are correlated with frontal hypometabolism in positron emission tomography studies of older alcoholic patients," Alcoholism: Clinical and Experimental Research, vol. 17 no. 2, pp. 205-210, DOI: 10.1111/j.1530-0277.1993.tb00750.x, 1993.
E. Oudman, T. C. Nijboer, A. Postma, J. W. Wijnia, S. Kerklaan, K. Lindsen, S. Van der Stigchel, "Acquisition of an instrumental activity of daily living in patients with Korsakoff’s syndrome: a comparison of trial and error and errorless learning," Neuropsychological Rehabilitation, vol. 23 no. 6, pp. 888-913, DOI: 10.1080/09602011.2013.835738, 2013.
M. Koch, A. L. Fitzpatrick, S. R. Rapp, R. L. Nahin, J. D. Williamson, O. L. Lopez, S. T. DeKosky, L. H. Kuller, R. H. Mackey, K. J. Mukamal, M. K. Jensen, K. M. Sink, "Alcohol consumption and risk of dementia and cognitive decline among older adults with or without mild cognitive impairment," JAMA Network Open, vol. 2 no. 9,DOI: 10.1001/jamanetworkopen.2019.10319, 2019.
P. T. Nunes, B. T. Kipp, N. L. Reitz, L. M. Savage, "Aging with alcohol-related brain damage: critical brain circuits associated with cognitive dysfunction," International Review of Neurobiology, vol. 148, pp. 101-168, DOI: 10.1016/bs.irn.2019.09.002, 2019.
M. Kivimäki, A. Singh-Manoux, G. D. Batty, S. Sabia, A. Sommerlad, S. Floud, M. Jokela, J. Vahtera, M. A. Beydoun, S. B. Suominen, A. Koskinen, A. Vaananen, M. Goldberg, M. Zins, L. Alfredsson, P. J. M. Westerholm, A. Knutsson, S. T. Nyberg, P. N. Sipila, J. V. Lindbohm, J. Pentti, G. Livingston, J. E. Ferrie, T. Strandberg, "Association of alcohol-induced loss of consciousness and overall alcohol consumption with risk for dementia," JAMA Network Open, vol. 3 no. 9,DOI: 10.1001/jamanetworkopen.2020.16084, 2020.
M. Schrader, S. Bamborschke, U. Lenk, A. Sterr, "Case Report: intensive inpatient neurorehabilitation achieves sustained real-world benefits in severe alcohol-related wernicke-korsakoff syndrome: a case study with 7-years follow-up," Frontiers in Psychology, vol. 12,DOI: 10.3389/fpsyg.2021.693920, 2021.
G. C. Hurtado, D. Rios, C. C. O. Dela, O. Trivino, BRI, L. Y. Mosquera, K. Bolanos, SEMINEC, K. Ordonez, L. P. Gutierrez, "Neurobehavioral disorders in a patient diagnosed with posttraumatic stress disorder and undifferentiated schizophrenia. clinical case of low prevalence and incidence in Colombia," Biomedical Research, vol. 29 no. 7,DOI: 10.4066/biomedicalresearch.29-17-1787, 2018.
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spelling Hurtado González, Carlos Alberto Ospina Otalvaro, SebastianMarmolejo Escobar, Carlos StevenQuebrada Mera, Karen JuliethOrtega Bolaños, LucelyGutiérrez Lenis, Paola Andrea Herrera Montoya, ValentinaSaldarriaga Viveros, Luis Miguel Beltrán Alomia, Juan Pablo Ayala Rico, Juan FelipeTorres Colorado, Luigui Andres2024-02-20T16:48:56Z2024-02-20T16:48:56Z2022-12Alberto Hurtado Gonzalez, C., Ospina Otalvaro, S., Marmolejo Escobar, C. S., Quebrada Mera, K. J., Arango de la Pava, P. M., Clavijo, C. A., Ortega Bolaños, L., Rátiva Hernández, N., Vidal Rosero, A. M., Gutierrez Lenis, P. A., Lucumí, A., Cappellaro Sánchez, J. P., Zamorano, A. A., Jacome, J. P., Herrera Montoya, V., Saldarriaga, L. M., Prado Salcedo, C., Alvarado Carranza, S. F., Marín Hoyos, C. A., … Arias Díaz, J. A. (2022). Neuropsychiatric Alterations in a Patient Diagnosed with Advanced Korsakoff’s Syndrome: Clinical Case of Low Incidence and Prevalence in Colombia. Case Reports in Medicine, 2022, 2772594–2772596. https://doi.org/10.1155/2022/2772594https://hdl.handle.net/20.500.12494/54991https://doi.org/10.1155/2022/277259416879635Korsakoff’s syndrome (KS) is an insidious and progressive neuropsychiatric disorder that affects specific neurocognitive functioning, especially in tasks that require sustained attention, memory, executive functions, and visuospatial functioning. Usually, this disease generates neuropsychiatric complications that worsen the quality of life (QOL) of patients in the medium term. We present a case of a 63-year-old male who presented with a diagnosis of advanced Korsakoff’s syndrome and has a clinical history of recurrent memory loss and a history of alcohol abuse. The patient showed difficulty manipulating immediate information, associated with a possible frontal lobe dysfunction, and inability to remember material given through the auditory pathway. The patient showed a psychiatric clinical picture which is constantly worsening his and his immediate caregiver’s QOL. The data obtained demonstrate that the patient presents a progressive cognitive impairment, which in the short term is correlated with Korsakoff-type dementia. It is suggested to carry out functional neurorehabilitation plans aimed at improving the QOL of the patient, his immediate caregiver, and future people with this type of diagnosis.El síndrome de Korsakoff (SK) es un trastorno neuropsiquiátrico insidioso y progresivo que afecta el funcionamiento neurocognitivo específico, especialmente en tareas que requieren atención sostenida, memoria, funciones ejecutivas y funcionamiento visuoespacial. Habitualmente, esta enfermedad genera complicaciones neuropsiquiátricas que empeoran la calidad de vida (CV) de los pacientes a medio plazo. Presentamos el caso de un varón de 63 años que presentó con diagnóstico de síndrome de Korsakoff avanzado y presenta antecedentes clínicos de pérdida de memoria recurrente y antecedentes de abuso de alcohol. El paciente presentaba dificultad para manipular información inmediata, asociada a una posible disfunción del lóbulo frontal, e incapacidad para recordar material transmitido a través de la vía auditiva. El paciente presenta un cuadro clínico psiquiátrico que empeora constantemente su calidad de vida y la de su cuidador inmediato. Los datos obtenidos demuestran que el paciente presenta un deterioro cognitivo progresivo, que a corto plazo se correlaciona con una demencia tipo Korsakoff. Se sugiere realizar planes de neurorrehabilitación funcional orientados a mejorar la CV del paciente, su cuidador inmediato y futuras personas con este tipo de diagnóstico.Patologías neurodegenerativas y neuropsiquíatricas6 p.application/pdfengUniversidad Cooperativa de Colombia, Facultad de Ciencias Sociales, Psicología, CaliCalihttps://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/closedAccessAtribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)http://purl.org/coar/access_right/c_14cbhttps://bbibliograficas.ucc.edu.co/login?url=https://www.proquest.com/scholarly-journals/neuropsychiatric-alterations-patient-diagnosed/docview/2761777083/se-2?accountid=44394Neuropsychiatric Alterations in a Patient Diagnosed with Advanced Korsakoff’s Syndrome: Clinical Case of Low Incidence and Prevalence in ColombiaArtículos Científicosinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersion12Case Reports in MedicinE. Isenberg-Grzeda, Y. Alici, V. Hatzoglou, C. Nelson, W. Breitbart, "Nonalcoholic thiamine-related encephalopathy (Wernicke-Korsakoff syndrome) among inpatients with cancer: a series of 18 cases," Psychosomatics, vol. 57 no. 1, pp. 71-81, DOI: 10.1016/j.psym.2015.10.001, 2016.R. Schliebs, T. Arendt, "The cholinergic system in aging and neuronal degeneration," Behavioural Brain Research, vol. 221 no. 2, pp. 555-563, DOI: 10.1016/j.bbr.2010.11.058, 2011.A. Anjum, "The amnestic syndrome," The Medical Basis of Psychiatry, pp. 43-51, 2016.P. J. Langlais, L. M. Savage, "Thiamine deficiency in rats produces cognitive and memory deficits on spatial tasks that correlate with tissue loss in diencephalon, cortex and white matter," Behavioural Brain Research, vol. 68 no. 1, pp. 75-89, DOI: 10.1016/0166-4328(94)00162-9, 1995.N. Butters, J. Brandt, "The continuity hypothesis the relationship of long-term alcoholism to the wernicke-korsakoff syndrome," Recent Developments in Alcoholism, pp. 207-226, 1985.M. Oscar‐Berman, S. M. Kirkley, D. A. Gansler, A. Couture, "Comparisons of Korsakoff and non‐korsakoff alcoholics on neuropsychological tests of prefrontal brain functioning," Alcoholism: Clinical and Experimental Research, vol. 28 no. 4, pp. 667-675, DOI: 10.1097/01.alc.0000122761.09179.b9, 2004.M. Oscar-Bemian, H. E. Schendan, "Asymmetries of brain function in alcoholism: relationship to aging," Neurobehavior of Language and Cognition, pp. 213-240, 2002.K. M. Adams, S. Gilman, R. A. Koeppe, K. J. Kluin, J. A. Brunberg, D. Dede, S. Berent, P. D. Kroll, "Neuropsychological deficits are correlated with frontal hypometabolism in positron emission tomography studies of older alcoholic patients," Alcoholism: Clinical and Experimental Research, vol. 17 no. 2, pp. 205-210, DOI: 10.1111/j.1530-0277.1993.tb00750.x, 1993.E. Oudman, T. C. Nijboer, A. Postma, J. W. Wijnia, S. Kerklaan, K. Lindsen, S. Van der Stigchel, "Acquisition of an instrumental activity of daily living in patients with Korsakoff’s syndrome: a comparison of trial and error and errorless learning," Neuropsychological Rehabilitation, vol. 23 no. 6, pp. 888-913, DOI: 10.1080/09602011.2013.835738, 2013.M. Koch, A. L. Fitzpatrick, S. R. Rapp, R. L. Nahin, J. D. Williamson, O. L. Lopez, S. T. DeKosky, L. H. Kuller, R. H. Mackey, K. J. Mukamal, M. K. Jensen, K. M. Sink, "Alcohol consumption and risk of dementia and cognitive decline among older adults with or without mild cognitive impairment," JAMA Network Open, vol. 2 no. 9,DOI: 10.1001/jamanetworkopen.2019.10319, 2019.P. T. Nunes, B. T. Kipp, N. L. Reitz, L. M. Savage, "Aging with alcohol-related brain damage: critical brain circuits associated with cognitive dysfunction," International Review of Neurobiology, vol. 148, pp. 101-168, DOI: 10.1016/bs.irn.2019.09.002, 2019.M. Kivimäki, A. Singh-Manoux, G. D. Batty, S. Sabia, A. Sommerlad, S. Floud, M. Jokela, J. Vahtera, M. A. Beydoun, S. B. Suominen, A. Koskinen, A. Vaananen, M. Goldberg, M. Zins, L. Alfredsson, P. J. M. Westerholm, A. Knutsson, S. T. Nyberg, P. N. Sipila, J. V. Lindbohm, J. Pentti, G. Livingston, J. E. Ferrie, T. Strandberg, "Association of alcohol-induced loss of consciousness and overall alcohol consumption with risk for dementia," JAMA Network Open, vol. 3 no. 9,DOI: 10.1001/jamanetworkopen.2020.16084, 2020.M. Schrader, S. Bamborschke, U. Lenk, A. Sterr, "Case Report: intensive inpatient neurorehabilitation achieves sustained real-world benefits in severe alcohol-related wernicke-korsakoff syndrome: a case study with 7-years follow-up," Frontiers in Psychology, vol. 12,DOI: 10.3389/fpsyg.2021.693920, 2021.G. C. Hurtado, D. Rios, C. C. O. Dela, O. Trivino, BRI, L. Y. Mosquera, K. Bolanos, SEMINEC, K. Ordonez, L. P. Gutierrez, "Neurobehavioral disorders in a patient diagnosed with posttraumatic stress disorder and undifferentiated schizophrenia. clinical case of low prevalence and incidence in Colombia," Biomedical Research, vol. 29 no. 7,DOI: 10.4066/biomedicalresearch.29-17-1787, 2018.Korsakoff’s syndrome (KS)Neurocognitive functioningSustained attentionMemoryExecutive functionsVisuospatial functioningAlcoholismPublicationLICENSElicense.txtlicense.txttext/plain; charset=utf-84334https://repository.ucc.edu.co/bitstreams/43c90c35-8121-426b-a35d-611b176c22e2/download3bce4f7ab09dfc588f126e1e36e98a45MD51ORIGINAL2022_neuropsychiatric_alterations2022_neuropsychiatric_alterationsapplication/pdf1092651https://repository.ucc.edu.co/bitstreams/3c8f5e2e-dfd1-4a26-bfee-4b478ee9982e/download226e061422bf81d21c25f32e584b60a3MD52TEXT2022_neuropsychiatric_alterations.txt2022_neuropsychiatric_alterations.txtExtracted 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